Activation of the ubiquitin-proteasome pathway in the diaphragm in chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 174, Issue 9, 2006, Pages 997-1002

  Ottenheijm, Coen A C ^a   Heunks, Leo M A ^b   Li, Yi Ping ^b   Jin, Bingwen ^b   Minnaard, Ronnie ^b   Van Hees, Hieronymus W H ^b   Dekhuijzen, P N Richard ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

Caspase 3; Chronic obstructive pulmonary disease; Diaphragm function; Myosin; Proteolysis

Indexed keywords

CASPASE 3; MESSENGER RNA; MYOSIN HEAVY CHAIN; PROTEASOME; UBIQUITIN PROTEIN LIGASE;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAPHRAGM MUSCLE; DISEASE SEVERITY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; HYDROLYSIS; MALE; MUSCLE BIOPSY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN DETERMINATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AGED; CASPASE 3; DIAPHRAGM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUSCLE CONTRACTION; MUSCLE PROTEINS; MYOSINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 33750600130     PISSN: 1073449X     EISSN: 1073449X     Source Type: Journal    
DOI: 10.1164/rccm.200605-721OC     Document Type: Article

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