Parvovirus B19 DNA CpG dinucleotide methylation and epigenetic regulation of viral expression

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Bonvicini, Francesca ^a   Manaresi, Elisabetta ^a   Di Furio, Francesca ^a   de Falco, Luisa ^a   Gallinella, Giorgio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; VIRUS DNA;

ARTICLE; CONTROLLED STUDY; CPG ISLAND; DISEASE ASSOCIATION; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; GENE EXPRESSION PROFILING; GENE SILENCING; GENETIC REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN PARVOVIRUS B19; HUMAN TISSUE; NONHUMAN; NUCLEOTIDE SEQUENCE; QUANTITATIVE REAL TIME POLYMERASE CHAIN REACTION; REAL TIME POLYMERASE CHAIN REACTION; VIRUS EXPRESSION; VIRUS GENOME; VIRUS INFECTION; VIRUS REPLICATION; CELL LINE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; PARVOVIRUS INFECTION; VIROLOGY; VIRUS LOAD;

DNA VIRUSES; PARVOVIRUS;

CELL LINE; CPG ISLANDS; DNA METHYLATION; DNA, VIRAL; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, VIRAL; GENOME, VIRAL; HUMANS; PARVOVIRIDAE INFECTIONS; PARVOVIRUS B19, HUMAN; VIRAL LOAD;

EID: 84857824527     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033316     Document Type: Article

References (42)

1. Berns KI, Parrish CR, (2007) Parvoviruses. In: Knipe DM, Howley PM, editors. Fields Virology. 4th ed Philadelphia Lippincott Williams & Wilkins pp. 2437-2477.
2. Young NS, Brown KE, (2004) Parvovirus B19. N Engl J Med 350: 586-597.
3. Broliden K, Tolfvenstam T, Norbeck O, (2006) Clinical aspects of parvovirus B19 infection. J Intern Med 260: 285-304.
4. Chisaka H, Morita E, Yaegashi N, Sugamura K, (2003) Parvovirus B19 and the pathogenesis of anaemia. Rev Med Virol 13: 347-359.
5. Tolfvenstam T, Broliden K, (2009) Parvovirus B19 infection. Semin Fetal Neonatal Med 14: 218-221.
6. von Landenberg P, Lehmann HW, Modrow S, (2007) Human parvovirus B19 infection and antiphospholipid antibodies. Autoimmun Rev 6: 278-285.
7. Norja P, Hokynar K, Aaltonen LM, Chen R, Ranki A, et al. (2006) Bioportfolio: lifelong persistence of variant and prototypic erythrovirus DNA genomes in human tissue. Proc Natl Acad Sci U S A 103: 7450-7453.
8. Servant-Delmas A, Lefrere JJ, Morinet F, Pillet S, (2010) Advances in human B19 erythrovirus biology. J Virol 84: 9658-9665.
9. Cotmore SF, Tattersall P, (1984) Characterization and molecular cloning of a human parvovirus genome. Science 226: 1161-1165.
10. Deiss V, Tratschin JD, Weitz M, Siegl G, (1990) Cloning of the human parvovirus B19 genome and structural analysis of its palindromic termini. Virology 175: 247-254.
11. Ozawa K, Kurtzman G, Young N, (1987) Productive infection by B19 parvovirus of human erythroid bone marrow cells in vitro. Blood 70: 384-391.
12. Zhi N, Mills IP, Lu J, Wong S, Filippone C, et al. (2006) Molecular and functional analyses of a human parvovirus B19 infectious clone demonstrates essential roles for NS1, VP1, and the 11-kilodalton protein in virus replication and infectivity. J Virol 80: 5941-5950.
13. Ozawa K, Ayub J, Hao YS, Kurtzman G, Shimada T, et al. (1987) Novel transcription map for the B19 (human) pathogenic parvovirus. J Virol 61: 2395-2406.
14. Ozawa K, Young N, (1987) Characterization of capsid and noncapsid proteins of B19 parvovirus propagated in human erythroid bone marrow cell cultures. J Virol 61: 2627-2630.
15. Bonvicini F, Filippone C, Delbarba S, Manaresi E, Zerbini M, et al. (2006) Parvovirus B19 genome as a single, two-state replicative and transcriptional unit. Virology 347: 447-454.
16. Bonvicini F, Filippone C, Manaresi E, Zerbini M, Musiani M, et al. (2008) Functional analysis and quantitative determination of the expression profile of human parvovirus B19. Virology 381: 168-177.
17. Chen AY, Guan W, Lou S, Liu Z, Kleiboeker S, et al. (2011) Role of erythropoietin receptor signaling in parvovirus B19 replication in human erythroid progenitor cells. J Virol 84: 12385-12396.
18. Gallinella G, Manaresi E, Zuffi E, Venturoli S, Bonsi L, et al. (2000) Different patterns of restriction to B19 parvovirus replication in human blast cell lines. Virology 278: 361-367.
19. Guan W, Wong S, Zhi N, Qiu J, (2009) The genome of human parvovirus B19 can replicate in nonpermissive cells with the help of adenovirus genes and produces infectious virus. J Virol 83: 9541-9553.
20. Raab U, Bauer B, Gigler A, Beckenlehner K, Wolf H, et al. (2001) Cellular transcription factors that interact with p6 promoter elements of parvovirus B19. J Gen Virol 82: 1473-1480.
21. Raab U, Beckenlehner K, Lowin T, Niller HH, Doyle S, et al. (2002) NS1 protein of parvovirus B19 interacts directly with DNA sequences of the p6 promoter and with the cellular transcription factors Sp1/Sp3. Virology 293: 86-93.
22. Wan Z, Zhi N, Wong S, Keyvanfar K, Liu D, et al. (2010) Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors. J Clin Invest 120: 3530-3544.
23. Portela A, Esteller M, (2010) Epigenetic modifications and human disease. Nat Biotechnol 28: 1057-1068.
24. Hoelzer K, Shackelton LA, Parrish CR, (2008) Presence and role of cytosine methylation in DNA viruses of animals. Nucleic Acids Res 36: 2825-2837.
25. Larsen F, Gundersen G, Lopez R, Prydz H, (1992) CpG islands as gene markers in the human genome. Genomics 13: 1095-1107.
26. Zhi N, Zadori Z, Brown KE, Tijssen P, (2004) Construction and sequencing of an infectious clone of the human parvovirus B19. Virology 318: 142-152.
27. Morita E, Nakashima A, Asao H, Sato H, Sugamura K, (2003) Human parvovirus B19 nonstructural protein (NS1) induces cell cycle arrest at G(1) phase. J Virol 77: 2915-2921.
28. Sundstrom C, Nilsson K, (1976) Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int J Cancer 17: 565-577.
29. Gallinella G, Bonvicini F, Filippone C, Delbarba S, Manaresi E, et al. (2004) Calibrated real-time PCR for evaluation of parvovirus B19 viral load. Clin Chem 50: 759-762.
30. Munakata Y, Kato I, Saito T, Kodera T, Ishii KK, et al. (2006) Human parvovirus B19 infection of monocytic cell line U937 and antibody-dependent enhancement. Virology 345: 251-257.
31. Pasquinelli G, Bonvicini F, Foroni L, Salfi N, Gallinella G, (2009) Placental endothelial cells can be productively infected by Parvovirus B19. J Clin Virol 44: 33-38.
32. Tassinari D, Gallinella G, Salfi NC, Elleri D, Forti S, et al. (2009) Gastrointestinal lesions in parvovirus B19 infection. BMJ Case Rep 2009.
33. Pironi L, Bonvicini F, Gionchetti P, D'Errico A, Rizzello F, et al. (2009) Parvovirus B19 infection localized in the intestinal mucosa and associated with severe inflammatory bowel disease. J Clin Microbiol 47: 1591-1595.
34. Bonvicini F, La Placa M, Manaresi E, Gallinella G, Gentilomi GA, et al. (2010) Parvovirus B19 DNA is commonly harboured in human skin. Dermatology 220: 138-142.
35. Fernandez AF, Esteller M, (2010) Viral epigenomes in human tumorigenesis. Oncogene 29: 1405-1420.
36. Gareus R, Gigler A, Hemauer A, Leruez-Ville M, Morinet F, et al. (1998) Characterization of cis-acting and NS1 protein-responsive elements in the p6 promoter of parvovirus B19. J Virol 72: 609-616.
37. Slotkin RK, Martienssen R, (2007) Transposable elements and the epigenetic regulation of the genome. Nat Rev Genet 8: 272-285.
38. Filippone C, Franssila R, Kumar A, Saikko L, Kovanen PE, et al. (2010) Erythroid progenitor cells expanded from peripheral blood without mobilization or preselection: molecular characteristics and functional competence. PLoS One 5: e9496.
39. Cotmore SF, Tattersall P, (2007) Parvoviral host range and cell entry mechanisms. Adv Virus Res 70: 183-232.
40. Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, et al. (2010) Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol 28: 1097-1105.
41. Deaton AM, Bird A, (2011) CpG islands and the regulation of transcription. Genes Dev 25: 1010-1022.
42. Guo YM, Ishii K, Hirokawa M, Tagawa H, Ohyagi H, et al. (2010) CpG-ODN 2006 and human parvovirus B19 genome consensus sequences selectively inhibit growth and development of erythroid progenitor cells. Blood 115: 4569-4579.