Histone deacetylation: An important mechanism in inflammatory lung diseases

COPD: Journal of Chronic Obstructive Pulmonary Disease

Volumn 2, Issue 4, 2005, Pages 445-455

  Adcock, Ian M ^a   Ito, Kazuhiro ^a   Barnes, Peter J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Chromatin; Histone acetylation; Histone acetyltransferase; Histone deacetylate; Transcription factor

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUTATHIONE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HYDROCORTISONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE SYNTHASE INHIBITOR; SUPEROXIDE DISMUTASE; THEOPHYLLINE;

ANTIINFLAMMATORY ACTIVITY; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CYSTIC FIBROSIS; DEACETYLATION; DISEASE SEVERITY; DNA BINDING; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; DRUG POTENTIATION; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE ACTIVATION; GENE EXPRESSION; GENE INDUCTION; GENE REPRESSION; GENE SWITCHING; GENETIC TRANSCRIPTION; HEADACHE; HEART ARRHYTHMIA; HUMAN; LOW DRUG DOSE; NAUSEA; NITRATION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PNEUMONIA; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REVIEW; SEIZURE; SMOOTH MUSCLE RELAXATION; UNSPECIFIED SIDE EFFECT; VIRUS INFECTION;

ACETYLATION; ANTI-INFLAMMATORY AGENTS; ASTHMA; BRONCHODILATOR AGENTS; GENE EXPRESSION; GLUCOCORTICOIDS; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASES; HISTONES; HUMANS; LUNG DISEASES; OXIDATIVE STRESS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REPRESSOR PROTEINS; THEOPHYLLINE;

EID: 33745099273     PISSN: 15412555     EISSN: 15412563     Source Type: Journal    
DOI: 10.1080/15412550500346683     Document Type: Review

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