메뉴 건너뛰기




Volumn 2, Issue 2, 2011, Pages 151-169

Epigenetic regulation of prostate cancer

Author keywords

DNA methylation; Epigenetics; Histone acetylation; MicroRNA; Prostate cancer

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; BICALUTAMIDE; BIOLOGICAL MARKER; DOCETAXEL; ENTINOSTAT; EPIGALLOCATECHIN GALLATE; GENISTEIN; GLUTATHIONE TRANSFERASE; HERMES ANTIGEN; HISTONE H3; HISTONE H4; HISTONE METHYLTRANSFERASE; HYDRALAZINE; LYSINE SPECIFIC DEMETHYLASE 1; MESSENGER RNA; MICRORNA; MICRORNA 221; MICRORNA 222; ONCOPROTEIN; PANOBINOSTAT; PROCAINAMIDE; ROMIDEPSIN; TRANSCRIPTION FACTOR EZH2; TRICHOSTATIN A; UNCLASSIFIED DRUG; UVOMORULIN; VALPROIC ACID; VORINOSTAT;

EID: 84856277683     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1007/s13148-011-0041-7     Document Type: Review
Times cited : (36)

References (189)
  • 1
    • 34247571817 scopus 로고    scopus 로고
    • RASSFIA promoter methylation is frequently detected in both pre-malignant and non-malignant microdissected prostatic epithelial tissues
    • DOI 10.1002/pros.20475
    • Aitchison A, Warren A, Neal D, Rabbitts P (2007) RASSF1A promoter methylation is frequently detected in both premalignant and non-malignant microdissected prostatic epithelial tissues. Prostate 67(6):638-644 (Pubitemid 46685284)
    • (2007) Prostate , vol.67 , Issue.6 , pp. 638-644
    • Aitchison, A.1    Warren, A.2    Neal, D.3    Rabbitts, P.4
  • 6
    • 2942596061 scopus 로고    scopus 로고
    • Die GSTP1-CpG-insel-hypermethylierung als molekularer marker des prostatakarzinoms
    • DOI 10.1007/s00120-004-0540-7
    • Bastian PJ, Nakayama M, De Marzo AM, Nelson WG (2004) GSTP1 CpG island hypermethylation as a molecular marker of prostate cancer. Urologe A 43(5):573-579 (Pubitemid 38756570)
    • (2004) Urologe - Ausgabe A , vol.43 , Issue.5 , pp. 573-579
    • Bastian, P.J.1    Nakayama, M.2    De Marzo, A.M.3    Nelson, W.G.4
  • 7
    • 20344366824 scopus 로고    scopus 로고
    • Preoperative serum DNA GSTP1 CpG island hypermethylation and the risk of early prostate-specific antigen recurrence following radical prostatectomy
    • DOI 10.1158/1078-0432.CCR-04-2446
    • Bastian PJ, Palapattu GS, Lin X, Yegnasubramanian S, Mangold LA, Trock B, Eisenberger MA, Partin AW, Nelson WG (2005) Preoperative serum DNA GSTP1 CpG island hypermethylation and the risk of early prostate-specific antigen recurrence following radical prostatectomy. Clin Cancer Res 11(11):4037-4043 (Pubitemid 40791567)
    • (2005) Clinical Cancer Research , vol.11 , Issue.11 , pp. 4037-4043
    • Bastian, P.J.1    Palapattu, G.S.2    Lin, X.3    Yegnasubramanian, S.4    Mangold, L.A.5    Trock, B.6    Eisenberger, M.A.7    Partin, A.W.8    Nelson, W.G.9
  • 8
    • 33846221516 scopus 로고    scopus 로고
    • Prognostic Value of CpG Island Hypermethylation at PTGS2, RAR-beta, EDNRB, and Other Gene Loci in Patients Undergoing Radical Prostatectomy
    • DOI 10.1016/j.eururo.2006.08.008, PII S0302283806009304
    • Bastian PJ, Ellinger J, Heukamp LC, Kahl P, Muller SC, von Rucker A (2007) Prognostic value of CpG island hypermethylation at PTGS2, RAR-beta, EDNRB, and other gene loci in patients undergoing radical prostatectomy. Eur Urol 51(3):665-674 (Pubitemid 46097267)
    • (2007) European Urology , vol.51 , Issue.3 , pp. 665-674
    • Bastian, P.J.1    Ellinger, J.2    Heukamp, L.C.3    Kahl, P.4    Muller, S.C.5    Von Rucker, A.6
  • 9
    • 79953788698 scopus 로고    scopus 로고
    • Pretreatment with anti-oxidants sensitizes oxidatively stressed human cancer cells to growth inhibitory effect of suberoylanilide hydroxamic acid (SAHA)
    • Basu HS, Mahlum A, Mehraein-Ghomi F, Kegel SJ, Guo S, Peters NR, Wilding G (2011) Pretreatment with anti-oxidants sensitizes oxidatively stressed human cancer cells to growth inhibitory effect of suberoylanilide hydroxamic acid (SAHA). Cancer Chemother Pharmacol 67(3):705-715
    • (2011) Cancer Chemother Pharmacol , vol.67 , Issue.3 , pp. 705-715
    • Basu, H.S.1    Mahlum, A.2    Mehraein-Ghomi, F.3    Kegel, S.J.4    Guo, S.5    Peters, N.R.6    Wilding, G.7
  • 11
    • 0023230209 scopus 로고
    • Hypomethylation of DNA in pathological conditions of the human prostate
    • Bedford MT, van Helden PD (1987) Hypomethylation of DNA in pathological conditions of the human prostate. Cancer Res 47 (20):5274-5276 (Pubitemid 17152932)
    • (1987) Cancer Research , vol.47 , Issue.20 , pp. 5274-5276
    • Bedford, M.T.1    Van Helden, P.D.2
  • 14
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • DOI 10.1101/gad.947102
    • Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16(1):6-21 (Pubitemid 34049633)
    • (2002) Genes and Development , vol.16 , Issue.1 , pp. 6-21
    • Bird, A.1
  • 22
    • 77952160818 scopus 로고    scopus 로고
    • MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta
    • Cao P, Deng Z, Wan M, Huang W, Cramer SD, Xu J, Lei M, Sui G (2010) MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta. Mol Cancer 9:108-120
    • (2010) Mol Cancer , vol.9 , pp. 108-120
    • Cao, P.1    Deng, Z.2    Wan, M.3    Huang, W.4    Cramer, S.D.5    Xu, J.6    Lei, M.7    Sui, G.8
  • 23
    • 39749155114 scopus 로고    scopus 로고
    • Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)
    • DOI 10.1007/s00280-007-0531-7
    • Cashen AF, Shah AK, Todt L, Fisher N, DiPersio J (2008) Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Cancer Chemother Pharmacol 61 (5):759-766 (Pubitemid 351302031)
    • (2008) Cancer Chemotherapy and Pharmacology , vol.61 , Issue.5 , pp. 759-766
    • Cashen, A.F.1    Shah, A.K.2    Todt, L.3    Fisher, N.4    DiPersio, J.5
  • 24
    • 79955513100 scopus 로고    scopus 로고
    • Aberrations of EZH2 in cancer
    • Chase A, Cross NC (2011) Aberrations of EZH2 in Cancer. Clin Cancer Res 17(9):2613-2618
    • (2011) Clin Cancer Res , vol.17 , Issue.9 , pp. 2613-2618
    • Chase, A.1    Cross, N.C.2
  • 25
    • 0030792699 scopus 로고    scopus 로고
    • Frequent alteration of CDKN2 (p16(INK4A)/MTS1) expression in human primary prostate carcinomas
    • Chi SG, deVere White RW, Muenzer JT, Gumerlock PH (1997) Frequent alteration of CDKN2 (p16(INK4A)/MTS1) expression in human primary prostate carcinomas. Clin Cancer Res 3 (10):1889-1897 (Pubitemid 27444732)
    • (1997) Clinical Cancer Research , vol.3 , Issue.10 , pp. 1889-1897
    • Chi, S.-G.1    DeVere White, R.W.2    Muenzer, J.T.3    Gumerlock, P.H.4
  • 27
    • 0036128290 scopus 로고    scopus 로고
    • The use of real-time quantitative polymerase chain reaction to detect hypermethylation of the CpG islands in the promoter region flanking the GSTP1 gene to diagnose prostate carcinoma
    • Chu DC, Chuang CK, Fu JB, Huang HS, Tseng CP, Sun CF (2002) The use of real-time quantitative polymerase chain reaction to detect hypermethylation of the CpG islands in the promoter region flanking the GSTP1 gene to diagnose prostate carcinoma. J Urol 167(4):1854-1858
    • (2002) J Urol , vol.167 , Issue.4 , pp. 1854-1858
    • Chu, D.C.1    Chuang, C.K.2    Fu, J.B.3    Huang, H.S.4    Tseng, C.P.5    Sun, C.F.6
  • 28
    • 27644597195 scopus 로고    scopus 로고
    • Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine
    • DOI 10.1158/1535-7163.MCT-05-0172
    • Chuang JC, Yoo CB, Kwan JM, Li TW, Liang G, Yang AS, Jones PA (2005) Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine. Mol Cancer Ther 4(10):1515-1520 (Pubitemid 41556433)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.10 , pp. 1515-1520
    • Chuang, J.C.1    Yoo, C.B.2    Kwan, J.M.3    Li, T.W.H.4    Liang, G.5    Yang, A.S.6    Jones, P.A.7
  • 29
    • 33847646837 scopus 로고    scopus 로고
    • Hypermethylation of the CpG islands in the promoter region flanking GSTP1 gene is a potential plasma DNA biomarker for detecting prostate carcinoma
    • Chuang CK, Chu DC, Tzou RD, Liou SI, Chia JH, Sun CF (2007) Hypermethylation of the CpG islands in the promoter region flanking GSTP1 gene is a potential plasma DNA biomarker for detecting prostate carcinoma. Cancer Detect Prev 31(1):59-63
    • (2007) Cancer Detect Prev , vol.31 , Issue.1 , pp. 59-63
    • Chuang, C.K.1    Chu, D.C.2    Tzou, R.D.3    Liou, S.I.4    Chia, J.H.5    Sun, C.F.6
  • 30
    • 77952203695 scopus 로고    scopus 로고
    • S110, a 5-Aza-2′-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth
    • Chuang JC, Warner SL, Vollmer D, Vankayalapati H, Redkar S, Bearss DJ, Qiu X, Yoo CB, Jones PA (2010) S110, a 5-Aza-2′-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. Mol Cancer Ther 9(5):1443-1450
    • (2010) Mol Cancer Ther , vol.9 , Issue.5 , pp. 1443-1450
    • Chuang, J.C.1    Warner, S.L.2    Vollmer, D.3    Vankayalapati, H.4    Redkar, S.5    Bearss, D.J.6    Qiu, X.7    Yoo, C.B.8    Jones, P.A.9
  • 31
    • 0016240205 scopus 로고
    • Biological effects of 5-azacytidine in eukaryotes
    • Cihak A (1974) Biological effects of 5-azacytidine in eukaryotes. Oncology 30(5):405-422
    • (1974) Oncology , vol.30 , Issue.5 , pp. 405-422
    • Cihak, A.1
  • 32
    • 79955119487 scopus 로고    scopus 로고
    • Pharmacologic disruption of polycomb repressive complex 2 inhibits tumorigenicity and tumor progression in prostate cancer
    • doi:10.1186/1476-4598-10-40
    • Crea F, Hurt EM, Mathews LA, Cabarcas SM, Sun L, Marquez VE, Danesi R, Farrar WL (2011) Pharmacologic disruption of polycomb repressive complex 2 inhibits tumorigenicity and tumor progression in prostate cancer. Mol Cancer 10(1):40. doi:10.1186/1476-4598-10-40
    • (2011) Mol Cancer , vol.10 , Issue.1 , pp. 40
    • Crea, F.1    Hurt, E.M.2    Mathews, L.A.3    Cabarcas, S.M.4    Sun, L.5    Marquez, V.E.6    Danesi, R.7    Farrar, W.L.8
  • 34
  • 37
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • Eden A, Gaudet F, Waghmare A, Jaenisch R (2003) Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300(5618):455-455
    • (2003) Science , vol.300 , Issue.5618 , pp. 455-455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 40
    • 38649101553 scopus 로고    scopus 로고
    • CpG Island Hypermethylation at Multiple Gene Sites in Diagnosis and Prognosis of Prostate Cancer
    • DOI 10.1016/j.urology.2007.09.056, PII S0090429507021929
    • Ellinger J, Bastian PJ, Jurgan T, Biermann K, Kahl P, Heukamp LC, Wernert N, Muller SC, von Ruecker A (2008c) CpG island hypermethylation at multiple gene sites in diagnosis and prognosis of prostate cancer. Urology 71(1):161-167 (Pubitemid 351173282)
    • (2008) Urology , vol.71 , Issue.1 , pp. 161-167
    • Ellinger, J.1    Bastian, P.J.2    Jurgan, T.3    Biermann, K.4    Kahl, P.5    Heukamp, L.C.6    Wernert, N.7    Muller, S.C.8    Von Ruecker, A.9
  • 42
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M (2008) Epigenetics in cancer. N Engl J Med 358(11):1148
    • (2008) N Engl J Med , vol.358 , Issue.11 , pp. 1148
    • Esteller, M.1
  • 43
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • DOI 10.1038/nrg1748
    • Feinberg A, Ohlsson R, Henikoff S (2006) The epigenetic progenitor origin of human cancer. Nature Rev Genet 7(1):21-33 (Pubitemid 41828945)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.1 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 48
    • 79955473684 scopus 로고    scopus 로고
    • Operating on chromatin, a colorful language where context matters
    • Gardner KE, Allis CD, Strahl BD (2011) Operating on chromatin, a colorful language where context matters. J Mol Biol 409(1):36-46
    • (2011) J Mol Biol , vol.409 , Issue.1 , pp. 36-46
    • Gardner, K.E.1    Allis, C.D.2    Strahl, B.D.3
  • 50
    • 40949102209 scopus 로고    scopus 로고
    • Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts
    • DOI 10.1016/j.bmc.2007.12.007, PII S0968089607010577
    • Gediya LK, Belosay A, Khandelwal A, Purushottamachar P, Njar VC (2008) Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts. Bioorg Med Chem 16(6):3352-3360 (Pubitemid 351418177)
    • (2008) Bioorganic and Medicinal Chemistry , vol.16 , Issue.6 , pp. 3352-3360
    • Gediya, L.K.1    Belosay, A.2    Khandelwal, A.3    Purushottamachar, P.4    Njar, V.C.O.5
  • 51
    • 0034872916 scopus 로고    scopus 로고
    • DNA-based detection of prostate cancer in urine after prostatic massage
    • DOI 10.1016/S0090-4295(01)01268-7, PII S0090429501012687
    • Goessl C, Muller M, Heicappell R, Krause H, Straub B, Schrader M, Miller K (2001) DNA-based detection of prostate cancer in urine after prostatic massage. Urology 58(3):335-338 (Pubitemid 32816344)
    • (2001) Urology , vol.58 , Issue.3 , pp. 335-338
    • Goessl, C.1    Muller, M.2    Heicappell, R.3    Krause, H.4    Straub, B.5    Schrader, M.6    Miller, K.7
  • 53
    • 77955975878 scopus 로고    scopus 로고
    • 5 Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors
    • Gravina G, Marampon F, Di Staso M, Bonfili P, Vitturini A, Jannini E, Pestell R, Tombolini V, Festuccia C (2010) 5 Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors. Prostate 70(11):1166-1178
    • (2010) Prostate , vol.70 , Issue.11 , pp. 1166-1178
    • Gravina, G.1    Marampon, F.2    Di Staso, M.3    Bonfili, P.4    Vitturini, A.5    Jannini, E.6    Pestell, R.7    Tombolini, V.8    Festuccia, C.9
  • 54
    • 1642358490 scopus 로고    scopus 로고
    • Linking the epigenetic 'language' of covalent histone modifications to cancer
    • DOI 10.1038/sj.bjc.6601575
    • Hake SB, Xiao A, Allis CD (2004) Linking the epigenetic 'language' of covalent histone modifications to cancer. Br J Cancer 90 (4):761-769 (Pubitemid 38406583)
    • (2004) British Journal of Cancer , vol.90 , Issue.4 , pp. 761-769
    • Hake, S.B.1    Xiao, A.2    Allis, C.D.3
  • 55
    • 1842631408 scopus 로고    scopus 로고
    • Upregulation and Nuclear Recruitment of HDACl in Hormone Refractory Prostate Cancer
    • DOI 10.1002/pros.20022
    • Halkidou K, Gaughan L, Cook S, Leung HY, Neal DE, Robson CN (2004) Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer. Prostate 59(2):177-189 (Pubitemid 38481229)
    • (2004) Prostate , vol.59 , Issue.2 , pp. 177-189
    • Halkidou, K.1    Gaughan, L.2    Cook, S.3    Leung, H.Y.4    Neal, D.E.5    Robson, C.N.6
  • 56
    • 33745013111 scopus 로고    scopus 로고
    • Oxidative stress and neurodegeneration: Where are we now?
    • DOI 10.1111/j.1471-4159.2006.03907.x
    • Halliwell B (2006) Oxidative stress and neurodegeneration: where are we now? J Neurochem 97(6):1634-1658 (Pubitemid 43873658)
    • (2006) Journal of Neurochemistry , vol.97 , Issue.6 , pp. 1634-1658
    • Halliwell, B.1
  • 58
    • 79953795978 scopus 로고    scopus 로고
    • Improvement of prostate cancer detection by integrating the PSA test with miRNA expression profiling
    • Hao Y, Zhao Y, Zhao X, He C, Pang X, Wu TC, Califano JA, Gu X (2011) Improvement of prostate cancer detection by integrating the PSA test with miRNA expression profiling. Cancer Invest 29 (4):318-324
    • (2011) Cancer Invest , vol.29 , Issue.4 , pp. 318-324
    • Hao, Y.1    Zhao, Y.2    Zhao, X.3    He, C.4    Pang, X.5    Wu, T.C.6    Califano, J.A.7    Gu, X.8
  • 59
    • 0037364371 scopus 로고    scopus 로고
    • Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma
    • DOI 10.1097/01.ju.0000049627.90307.4d
    • Harden SV, Guo Z, Epstein JI, Sidransky D (2003) Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma. J Urol 169(3):1138-1142 (Pubitemid 36188189)
    • (2003) Journal of Urology , vol.169 , Issue.3 , pp. 1138-1142
    • Harden, S.V.1    Guo, Z.2    Epstein, J.I.3    Sidransky, D.4
  • 60
    • 0034713275 scopus 로고    scopus 로고
    • CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
    • DOI 10.1038/35013106
    • Hark AT, Schoenherr CJ, Katz DJ, Ingram RS, Levorse JM, Tilghman SM (2000) CTCF mediates methylation-sensitive enhancerblocking activity at the H19/Igf2 locus. Nature 405(6785):486-489 (Pubitemid 30367428)
    • (2000) Nature , vol.405 , Issue.6785 , pp. 486-489
    • Hark, A.T.1    Schoenherr, C.J.2    Katz, D.J.3    Ingram, R.S.4    Levorse, J.M.5    Tilghman, S.M.6
  • 62
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • DOI 10.1038/nrg1379
    • He L, Hannon GJ (2004) MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5(7):522-531 (Pubitemid 38868508)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 65
    • 33847358769 scopus 로고    scopus 로고
    • The role of RASSF1A methylation in cancer
    • Epigenetic Markers
    • Hesson LB, Cooper WN, Latif F (2007) The role of RASSF1A methylation in cancer. Dis Markers 23(1-2):73-87 (Pubitemid 46333640)
    • (2007) Disease Markers , vol.23 , Issue.1-2 , pp. 73-87
    • Hesson, L.B.1    Cooper, W.N.2    Latif, F.3
  • 66
    • 0033564458 scopus 로고    scopus 로고
    • Carboxypeptidase A3 (CPA3): A novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells
    • Huang H, Reed CP, Zhang JS, Shridhar V, Wang L, Smith DI (1999) Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. Cancer Res 59(12):2981-2988 (Pubitemid 29283141)
    • (1999) Cancer Research , vol.59 , Issue.12 , pp. 2981-2988
    • Huang, H.1    Reed, C.P.2    Zhang, J.-S.3    Shridhar, V.4    Wang, L.5    Smith, D.I.6
  • 67
    • 33749260689 scopus 로고    scopus 로고
    • Quantitative analysis of plasma circulating DNA at diagnosis and during follow-up of breast cancer patients
    • DOI 10.1016/j.canlet.2005.11.027, PII S0304383505010281
    • Huang ZH, Li LH, Hua D (2006) Quantitative analysis of plasma circulating DNA at diagnosis and during follow-up of breast cancer patients. Cancer Lett 243(1):64-70 (Pubitemid 44485325)
    • (2006) Cancer Letters , vol.243 , Issue.1 , pp. 64-70
    • Huang, Z.H.1    Li, L.H.2    Hua, D.3
  • 68
    • 0033028789 scopus 로고    scopus 로고
    • Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis
    • DOI 10.1038/10525
    • Hulett MD, Freeman C, Hamdorf BJ, Baker RT, Harris MJ, Parish CR (1999) Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis. Nat Med 5(7):803-809 (Pubitemid 29318615)
    • (1999) Nature Medicine , vol.5 , Issue.7 , pp. 803-809
    • Hulett, M.D.1    Freeman, C.2    Hamdorf, B.J.3    Baker, R.T.4    Harris, M.J.5    Parish, C.R.6
  • 69
    • 67349255210 scopus 로고    scopus 로고
    • CpG islands-'a rough guide
    • Illingworth R, Bird A (2009) CpG islands-'a rough guide'. FEBS Lett 583(11):1713-1720
    • (2009) FEBS Lett , vol.583 , Issue.11 , pp. 1713-1720
    • Illingworth, R.1    Bird, A.2
  • 70
    • 0031001563 scopus 로고    scopus 로고
    • Mutagenicity of 5-aza-2′-deoxycytidine is mediated by the mammalian DNA methyltransferase
    • Jackson-Grusby L, Laird PW, Magge SN, Moeller BJ, Jaenisch R (1997) Mutagenicity of 5-aza-2′-deoxycytidine is mediated by the mammalian DNA methyltransferase. Proc Natl Acad Sci USA 94(9):4681-4685
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.9 , pp. 4681-4685
    • Jackson-Grusby, L.1    Laird, P.W.2    Magge, S.N.3    Moeller, B.J.4    Jaenisch, R.5
  • 71
    • 0035866393 scopus 로고    scopus 로고
    • DNA fragments in the blood plasma of cancer patients: Quantitations and evidence for their origin from apoptotic and necrotic cells
    • Jahr S, Hentze H, Englisch S, Hardt D, Fackelmayer FO, Hesch RD, Knippers R (2001) DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res 61(4):1659-1665 (Pubitemid 34292602)
    • (2001) Cancer Research , vol.61 , Issue.4 , pp. 1659-1665
    • Jahr, S.1    Hentze, H.2    Englisch, S.3    Hardt, D.4    Fackelmayer, F.O.5    Hesch, R.-D.6    Knippers, R.7
  • 73
    • 0032403081 scopus 로고    scopus 로고
    • Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells
    • Jarrard DF, Kinoshita H, Shi Y, Sandefur C, Hoff D, Meisner LF, Chang C, Herman JG, Isaacs WB, Nassif N (1998) Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells. Cancer Res 58(23):5310-5314 (Pubitemid 28551106)
    • (1998) Cancer Research , vol.58 , Issue.23 , pp. 5310-5314
    • Jarrard, D.F.1    Kinoshita, H.2    Shi, Y.3    Sandefur, C.4    Hoff, D.5    Meisner, L.F.6    Chang, C.7    Herman, J.G.8    Isaacs, W.B.9    Nassif, N.10
  • 74
    • 0032827195 scopus 로고    scopus 로고
    • The role of the androgen receptor in the development and progression of prostate cancer
    • Jenster G (1999) The role of the androgen receptor in the development and progression of prostate cancer. Semin Oncol 26(4):407-421 (Pubitemid 29411449)
    • (1999) Seminars in Oncology , vol.26 , Issue.4 , pp. 407-421
    • Jenster, G.1
  • 75
    • 0036899057 scopus 로고    scopus 로고
    • Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer
    • DOI 10.1016/S0090-4295(02)01949-0, PII S0090429502019490
    • Jeronimo C, Usadel H, Henrique R, Silva C, Oliveira J, Lopes C, Sidransky D (2002) Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer. Urology 60 (6):1131-1135 (Pubitemid 35447593)
    • (2002) Urology , vol.60 , Issue.6 , pp. 1131-1135
    • Jeronimo, C.1    Usadel, H.2    Henrique, R.3    Silva, C.4    Oliveira, J.5    Lopes, C.6    Sidransky, D.7
  • 77
    • 33847065486 scopus 로고    scopus 로고
    • The Epigenomics of Cancer
    • DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
    • Jones PA, Baylin SB (2007) The epigenomics of cancer. Cell 128 (4):683-692 (Pubitemid 46273572)
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 78
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • Jones P, Taylor S (1980) Cellular differentiation, cytidine analogs and DNA methylation. Cell 20(1):85-93 (Pubitemid 10117303)
    • (1980) Cell , vol.20 , Issue.1 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 82
    • 0035576259 scopus 로고    scopus 로고
    • Decreased expression of catenins (α and β), p120 CTN, and E-cadherin cell adhesion proteins and E-cadherin gene promoter methylation in prostatic adenocarcinomas
    • DOI 10.1002/1097-0142(20011201)92:11<2786::AID-CNCR10128>3.0.CO;2-I
    • Kallakury BV, Sheehan CE, Winn-Deen E, Oliver J, Fisher HA, Kaufman RP Jr, Ross JS (2001) Decreased expression of catenins (alpha and beta), p120 CTN, and E-cadherin cell adhesion proteins and E-cadherin gene promoter methylation in prostatic adenocarcinomas. Cancer 92(11):2786-2795 (Pubitemid 33091915)
    • (2001) Cancer , vol.92 , Issue.11 , pp. 2786-2795
    • Kallakury, B.V.S.1    Sheehan, C.E.2    Winn-Deen, E.3    Oliver, J.4    Fisher, H.A.G.5    Kaufman Jr., R.P.6    Ross, J.S.7
  • 84
    • 1142275110 scopus 로고    scopus 로고
    • Aberrant CpG island hypermethylation of multiple genes in prostate cancer and prostatic intraepithelial neoplasia
    • DOI 10.1002/path.1503
    • Kang GH, Lee S, Lee HJ, Hwang KS (2004) Aberrant CpG island hypermethylation of multiple genes in prostate cancer and prostatic intraepithelial neoplasia. J Pathol 202(2):233-240 (Pubitemid 38208661)
    • (2004) Journal of Pathology , vol.202 , Issue.2 , pp. 233-240
    • Kang, G.H.1    Lee, S.2    Lee, H.J.3    Hwang, K.S.4
  • 86
    • 77950874502 scopus 로고    scopus 로고
    • Comprehensive evaluation of the role of EZH2 in the growth, invasion, and aggression of a panel of prostate cancer cell lines
    • Karanikolas B, Figueiredo M, Wu L (2010) Comprehensive evaluation of the role of EZH2 in the growth, invasion, and aggression of a panel of prostate cancer cell lines. Prostate 70(6):675-688
    • (2010) Prostate , vol.70 , Issue.6 , pp. 675-688
    • Karanikolas, B.1    Figueiredo, M.2    Wu, L.3
  • 88
    • 0033529565 scopus 로고    scopus 로고
    • Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
    • DOI 10.1016/S0092-8674(00)81958-3
    • Kornberg RD, Lorch Y (1999) Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome. Cell 98 (3):285-294 (Pubitemid 29380564)
    • (1999) Cell , vol.98 , Issue.3 , pp. 285-294
    • Kornberg, R.D.1    Lorch, Y.2
  • 89
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin Modifications and Their Function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • Kouzarides T (2007) Chromatin modifications and their function. Cell 128(4):693-705 (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 90
    • 0033169062 scopus 로고    scopus 로고
    • Differential effects of vitamin D on normal human prostate epithelial and stromal cells in primary culture
    • DOI 10.1016/S0090-4295(99)00103-X, PII S009042959900103X
    • Krill D, Stoner J, Konety BR, Becich MJ, Getzenberg RH (1999) Differential effects of vitamin D on normal human prostate epithelial and stromal cells in primary culture. Urology 54 (1):171-177 (Pubitemid 29323353)
    • (1999) Urology , vol.54 , Issue.1 , pp. 171-177
    • Krill, D.1    Stoner, J.2    Konety, B.R.3    Becich, M.J.4    Getzenberg, R.H.5
  • 91
    • 33749029926 scopus 로고    scopus 로고
    • Antitumor effects of a novel phenylbutyrate-based histone deacetylase inhibitor, (S)-HDAC-42, in prostate cancer
    • DOI 10.1158/1078-0432.CCR-06-0429
    • Kulp SK, Chen CS, Wang DS, Chen CY (2006) Antitumor effects of a novel phenylbutyrate-based histone deacetylase inhibitor, (S)-HDAC-42, in prostate cancer. Clin Cancer Res 12(17):5199-5206 (Pubitemid 44453349)
    • (2006) Clinical Cancer Research , vol.12 , Issue.17 , pp. 5199-5206
    • Kulp, S.K.1    Chen, C.-S.2    Wang, D.-S.3    Chen, C.-Y.4    Chen, C.-S.5
  • 92
    • 39649083125 scopus 로고    scopus 로고
    • Depsipeptide (FK228) inhibits growth of human prostate cancer cells
    • Lai MT, Yang CC, Lin TY, Tsai FJ, Chen WC (2008) Depsipeptide (FK228) inhibits growth of human prostate cancer cells. Urol Oncol 26(2):182-189
    • (2008) Urol Oncol , vol.26 , Issue.2 , pp. 182-189
    • Lai, M.T.1    Yang, C.C.2    Lin, T.Y.3    Tsai, F.J.4    Chen, W.C.5
  • 93
    • 33646517941 scopus 로고    scopus 로고
    • SAHA-sensitized prostate cancer cells to TNFalpha-related apoptosis-inducing ligand (TRAIL): Mechanisms leading to synergistic apoptosis
    • Lakshmikanthan V, Kaddour-Djebbar I, Lewis RW, Kumar MV (2006) SAHA-sensitized prostate cancer cells to TNFalpha-related apoptosis-inducing ligand (TRAIL): mechanisms leading to synergistic apoptosis. Int J Cancer 119(1):221-228
    • (2006) Int J Cancer , vol.119 , Issue.1 , pp. 221-228
    • Lakshmikanthan, V.1    Kaddour-Djebbar, I.2    Lewis, R.W.3    Kumar, M.V.4
  • 95
    • 34250897975 scopus 로고    scopus 로고
    • GSTP1 promoter hypermethylation is an early event in breast carcinogenesis
    • DOI 10.1007/s00428-007-0421-8
    • Lee J (2007) GSTP1 promoter hypermethylation is an early event in breast carcinogenesis. Virchows Arch 450(6):637-642 (Pubitemid 46986235)
    • (2007) Virchows Archiv , vol.450 , Issue.6 , pp. 637-642
    • Lee, J.S.1
  • 97
    • 28844497663 scopus 로고    scopus 로고
    • Procainamide is a specific inhibitor of DNA methyltransferase 1
    • DOI 10.1074/jbc.M505593200
    • Lee BH, Yegnasubramanian S, Lin X, Nelson WG (2005) Procainamide is a specific inhibitor of DNA methyltransferase 1. J Biol Chem 280 (49):40749-40756 (Pubitemid 41780565)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.49 , pp. 40749-40756
    • Lee, B.H.1    Yegnasubramanian, S.2    Lin, X.3    Nelson, W.G.4
  • 98
    • 79953888351 scopus 로고    scopus 로고
    • Percentage of free prostate-specific antigen: Implications in modern extended scheme prostate biopsy
    • Lee B, Moussa A, Li J, Fareed K, Jones J (2011) Percentage of Free Prostate-specific Antigen: Implications in Modern Extended Scheme Prostate Biopsy. Urology 77(4):899-903
    • (2011) Urology , vol.77 , Issue.4 , pp. 899-903
    • Lee, B.1    Moussa, A.2    Li, J.3    Fareed, K.4    Jones, J.5
  • 101
    • 0035893767 scopus 로고    scopus 로고
    • Reversal of GSTP1 CpG island hypermethylation and reactivation of π-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide
    • Lin X, Asgari K, Putzi MJ, Gage WR, Yu X, Cornblatt BS, Kumar A, Piantadosi S, DeWeese TL, De Marzo AM, Nelson WG (2001a) Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide. Cancer Res 61(24):8611-8616 (Pubitemid 34013864)
    • (2001) Cancer Research , vol.61 , Issue.24 , pp. 8611-8616
    • Lin, X.1    Asgari, K.2    Putzi, M.J.3    Gage, W.R.4    Yu, X.5    Cornblatt, B.S.6    Kumar, A.7    Piantadosi, S.8    DeWeese, T.L.9    De Marzo, A.M.10    Nelson, W.G.11
  • 103
    • 0037015688 scopus 로고    scopus 로고
    • Frequent hypermethylation of the RASSF1A gene in prostate cancer
    • DOI 10.1038/sj.onc.1205814
    • Liu L, Yoon JH, Dammann R, Pfeifer GP (2002) Frequent hypermethylation of the RASSF1A gene in prostate cancer. Oncogene 21(44):6835-6840 (Pubitemid 35221926)
    • (2002) Oncogene , vol.21 , Issue.44 , pp. 6835-6840
    • Liu, L.1    Yoon, J.-H.2    Dammann, R.3    Pfeifer, G.P.4
  • 107
    • 0001746766 scopus 로고    scopus 로고
    • Role of p27 in prostate carcinogenesis
    • DOI 10.1023/A:1006133620914
    • Macri E, Loda M (1998) Role of p27 in prostate carcinogenesis. Cancer Metastasis Rev 17(4):337-344 (Pubitemid 29331783)
    • (1999) Cancer and Metastasis Reviews , vol.17 , Issue.4 , pp. 337-344
    • Macri, E.1    Loda, M.2
  • 108
    • 33846839622 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation
    • DOI 10.1158/1535-7163.MCT-06-0144
    • Marrocco DL, Tilley WD, Bianco-Miotto T, Evdokiou A, Scher HI, Rifkind RA, Marks PA, Richon VM, Butler LM (2007) Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation. Mol Cancer Ther 6(1):51-60 (Pubitemid 46209918)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.1 , pp. 51-60
    • Marrocco, D.L.1    Tilley, W.D.2    Bianco-Miotto, T.3    Evdokiou, A.4    Scher, H.I.5    Rifkind, R.A.6    Marks, P.A.7    Richon, V.M.8    Butler, L.M.9
  • 110
    • 24144462170 scopus 로고    scopus 로고
    • LSD1 demethylates repressive histone marks to promote androgen-receptor- dependent transcription
    • DOI 10.1038/nature04020, PII N04020
    • Metzger E, Wissmann M, Yin N, Muller JM, Schneider R, Peters AH, Gunther T, Buettner R, Schule R (2005) LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 437(7057):436-439 (Pubitemid 41613508)
    • (2005) Nature , vol.437 , Issue.7057 , pp. 436-439
    • Metzger, E.1    Wissmann, M.2    Yin, N.3    Muller, J.M.4    Schneider, R.5    Peters, A.H.F.M.6    Gunther, T.7    Buettner, R.8    Schule, R.9
  • 111
    • 0029096145 scopus 로고
    • Vitamin D receptor expression, 24-hydroxylase activity, and inhibition of growth by 1alpha, 25-dihydroxyvitamin D3 in seven human prostatic carcinoma cell lines
    • Miller GJ, Stapleton GE, Hedlund TE, Moffat KA (1995) Vitamin D receptor expression, 24-hydroxylase activity, and inhibition of growth by 1alpha, 25-dihydroxyvitamin D3 in seven human prostatic carcinoma cell lines. Clin Cancer Res 1(9):997-1003
    • (1995) Clin Cancer Res , vol.1 , Issue.9 , pp. 997-1003
    • Miller, G.J.1    Stapleton, G.E.2    Hedlund, T.E.3    Moffat, K.A.4
  • 112
    • 67649371461 scopus 로고    scopus 로고
    • DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
    • Miranda TB, Cortez CC, Yoo CB, Liang G, Abe M, Kelly TK, Marquez VE, Jones PA (2009) DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Mol Cancer Ther 8(6):1579-1588
    • (2009) Mol Cancer Ther , vol.8 , Issue.6 , pp. 1579-1588
    • Miranda, T.B.1    Cortez, C.C.2    Yoo, C.B.3    Liang, G.4    Abe, M.5    Kelly, T.K.6    Marquez, V.E.7    Jones, P.A.8
  • 116
    • 0041924823 scopus 로고    scopus 로고
    • Hypermethylation of the human glutathione S-transferase-π gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: A detailed study using laser-capture microdissection
    • Nakayama M, Bennett CJ, Hicks JL, Epstein JI, Platz EA, Nelson WG, De Marzo AM (2003) Hypermethylation of the human glutathione S-transferase-pi gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: a detailed study using laser-capture microdissection. Am J Pathol 163 (3):923-933 (Pubitemid 37040128)
    • (2003) American Journal of Pathology , vol.163 , Issue.3 , pp. 923-933
    • Nakayama, M.1    Bennett, C.J.2    Hicks, J.L.3    Epstein, J.I.4    Platz, E.A.5    Nelson, W.G.6    De Marzo, A.M.7
  • 117
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • DOI 10.1038/30764
    • Nan X, Ng H, Johnson C, Laherty C, Turner B, Eisenman R, Bird A (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393(6683):386-389 (Pubitemid 28269714)
    • (1998) Nature , vol.393 , Issue.6683 , pp. 386-389
    • Nan, X.1    Ng, H.-H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 118
    • 0037083757 scopus 로고    scopus 로고
    • Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation
    • DOI 10.1101/gad.967202
    • Nishioka K, Chuikov S, Sarma K, Erdjument-Bromage H, Allis CD, Tempst P, Reinberg D (2002) Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev 16(4):479-489 (Pubitemid 34165104)
    • (2002) Genes and Development , vol.16 , Issue.4 , pp. 479-489
    • Nishioka, K.1    Chuikov, S.2    Sarma, K.3    Erdjument-Bromage, H.4    Allis, C.D.5    Tempst, P.6    Reinberg, D.7
  • 122
    • 0037709969 scopus 로고    scopus 로고
    • Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo
    • DOI 10.1096/fj.02-0973com
    • Pakneshan P, Xing R, Rabbani S (2003) Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo. FASEB J 17(9):1081-1088 (Pubitemid 36676394)
    • (2003) FASEB Journal , vol.17 , Issue.9 , pp. 1081-1088
    • Pakneshan, P.1    Xing, R.H.2    Rabbani, S.A.3
  • 126
    • 34547128128 scopus 로고    scopus 로고
    • + cell population is enriched in tumor-initiating cells
    • DOI 10.1158/0008-5472.CAN-07-0490
    • Patrawala L, Calhoun-Davis T, Schneider-Broussard R, Tang DG (2007) Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells. Cancer Res 67(14):6796-6805 (Pubitemid 47105527)
    • (2007) Cancer Research , vol.67 , Issue.14 , pp. 6796-6805
    • Patrawala, L.1    Calhoun-Davis, T.2    Schneider-Broussard, R.3    Tang, D.G.4
  • 127
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • DOI 10.1038/32433
    • Perl A, Wilgenbus P, Dahl U, Semb H, Christofori G (1998) A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392(6672):190-193 (Pubitemid 28162793)
    • (1998) Nature , vol.392 , Issue.6672 , pp. 190-193
    • Peri, A.-K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 128
    • 13844322498 scopus 로고
    • Induction of gene amplification by 5-aza-2′-deoxycytidine
    • Perry ME, Rolfe M, McIntyre P, Commane M, Stark GR (1992) Induction of gene amplification by 5-aza-2′-deoxycytidine. Mutat Res 276(3):189-197
    • (1992) Mutat Res , vol.276 , Issue.3 , pp. 189-197
    • Perry, M.E.1    Rolfe, M.2    McIntyre, P.3    Commane, M.4    Stark, G.R.5
  • 129
    • 21544483241 scopus 로고    scopus 로고
    • Methylation of the tumor suppressor gene RASSF1A in human tumors
    • DOI 10.1007/s10541-005-0151-y
    • Pfeifer GP, Dammann R (2005) Methylation of the tumor suppressor gene RASSF1A in human tumors. Biochemistry (Mosc) 70 (5):576-583 (Pubitemid 40920802)
    • (2005) Biochemistry (Moscow) , vol.70 , Issue.5 , pp. 576-583
    • Pfeifer, G.P.1    Dammann, R.2
  • 130
    • 77951748989 scopus 로고    scopus 로고
    • Methylated genes as potential biomarkers in prostate cancer
    • Phé V, Cussenot O, Rouprêt M (2010) Methylated genes as potential biomarkers in prostate cancer. BJUI 105(10):1364-1370
    • (2010) BJUI , vol.105 , Issue.10 , pp. 1364-1370
    • Phé, V.1    Cussenot, O.2    Rouprêt, M.3
  • 132
    • 19544386612 scopus 로고    scopus 로고
    • In vivo imaging of retinoic acid receptor β2 transcriptional activation by the histone deacetylase inhibitor MS-275 in retinoid-resistant prostate cancer cells
    • DOI 10.1002/pros.20209
    • Qian DZ, Ren M, Wei Y, Wang X, van de Geijn F, Rasmussen C, Nakanishi O, Sacchi N, Pili R (2005) In vivo imaging of retinoic acid receptor beta2 transcriptional activation by the histone deacetylase inhibitor MS-275 in retinoid-resistant prostate cancer cells. Prostate 64(1):20-28 (Pubitemid 40734735)
    • (2005) Prostate , vol.64 , Issue.1 , pp. 20-28
    • Qian, D.Z.1    Ren, M.2    Wei, Y.3    Wang, X.4    Van De Geijn, F.5    Rasmussen, C.6    Nakanishi, O.7    Sacchi, N.8    Pili, R.9
  • 134
    • 34547662889 scopus 로고    scopus 로고
    • Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models
    • DOI 10.1002/pros.20611
    • Qian DZ, Wei YF, Wang X, Kato Y, Cheng L, Pili R (2007) Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models. Prostate 67(11):1182-1193 (Pubitemid 47221885)
    • (2007) Prostate , vol.67 , Issue.11 , pp. 1182-1193
    • Qian, D.Z.1    Wei, Y.-F.2    Wang, X.3    Kato, Y.4    Cheng, L.5    Pili, R.6
  • 135
    • 0035810045 scopus 로고    scopus 로고
    • 3 and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A
    • DOI 10.1038/sj.onc.1204269
    • Rashid SF, Moore JS, Walker E, Driver PM, Engel J, Edwards CE, Brown G, Uskokovic MR, Campbell MJ (2001) Synergistic growth inhibition of prostate cancer cells by 1 alpha, 25 dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. Oncogene 20(15):1860-1872 (Pubitemid 32458696)
    • (2001) Oncogene , vol.20 , Issue.15 , pp. 1860-1872
    • Rashid, S.F.1    Moore, J.S.2    Walker, E.3    Driver, P.M.4    Engel, J.5    Edwards, C.E.6    Brown, G.7    Uskokovic, M.R.8    Campbell, M.J.9
  • 137
    • 33847386223 scopus 로고    scopus 로고
    • Promoter hypermethylation of GSTP1, AR, and 14-3-3σ in serum of prostate cancer patients and its clinical relevance
    • DOI 10.1002/pros.20533
    • Reibenwein J, Pils D, Horak P, Tomicek B, Goldner G, Worel N, Elandt K, Krainer M (2007) Promoter hypermethylation of GSTP1, AR, and 14-3-3sigma in serum of prostate cancer patients and its clinical relevance. Prostate 67(4):427-432 (Pubitemid 46341084)
    • (2007) Prostate , vol.67 , Issue.4 , pp. 427-432
    • Reibenwein, J.1    Pils, D.2    Horak, P.3    Tomicek, B.4    Goldner, G.5    Worel, N.6    Elandt, K.7    Krainer, M.8
  • 139
    • 28544442448 scopus 로고    scopus 로고
    • Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy
    • DOI 10.1158/1078-0432.CCR-05-1183
    • Rosenbaum E, Hoque MO, Cohen Y, Zahurak M, Eisenberger MA, Epstein JI, Partin AW, Sidransky D (2005) Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy. Clin Cancer Res 11(23):8321-8325 (Pubitemid 41746943)
    • (2005) Clinical Cancer Research , vol.11 , Issue.23 , pp. 8321-8325
    • Rosenbaum, E.1    Hoque, M.O.2    Cohen, Y.3    Zahurak, M.4    Eisenberger, M.A.5    Epstein, J.I.6    Partin, A.W.7    Sidransky, D.8
  • 142
    • 0033135573 scopus 로고    scopus 로고
    • High frequency of alterations in DNA methylation in adenocarcinoma of the prostate
    • DOI 10.1002/(SICI)1097-0045(19990515)39:3<166::AID-PROS4>3.0.CO;2-J
    • Santourlidis S, Florl A, Ackermann R, Wirtz HC, Schulz WA (1999) High frequency of alterations in DNA methylation in adenocarcinoma of the prostate. Prostate 39(3):166-174 (Pubitemid 29203403)
    • (1999) Prostate , vol.39 , Issue.3 , pp. 166-174
    • Santourlidis, S.1    Florl, A.2    Ackermann, R.3    Wirtz, H.-C.4    Schulz, W.A.5
  • 143
    • 10744231450 scopus 로고    scopus 로고
    • Effects of 5-aza-2′-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease
    • DOI 10.1182/blood-2003-05-1738
    • Saunthararajah Y, Hillery C, Lavelle D, Molokie R, Dorn L, Bressler L, Gavazova S, Chen Y, Hoffman R, DeSimone J (2003) Effects of 5-aza-2′- deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease. Blood 102(12):3865-3870 (Pubitemid 37486964)
    • (2003) Blood , vol.102 , Issue.12 , pp. 3865-3870
    • Saunthararajah, Y.1    Hillery, C.A.2    Lavelle, D.3    Molokie, R.4    Dorn, L.5    Bressler, L.6    Gavazova, S.7    Chen, Y.-H.8    Hoffman, R.9    DeSimone, J.10
  • 145
    • 78650710470 scopus 로고    scopus 로고
    • Sustained exposure to the DNA demethylating agent, 2′-deoxy-5- azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy
    • Schnekenburger M, Grandjenette C, Ghelfi J, Karius T, Foliguet B, Dicato M, Diederich M (2011) Sustained exposure to the DNA demethylating agent, 2′-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy. Biochem Pharmacol 81(3):364-378
    • (2011) Biochem Pharmacol , vol.81 , Issue.3 , pp. 364-378
    • Schnekenburger, M.1    Grandjenette, C.2    Ghelfi, J.3    Karius, T.4    Foliguet, B.5    Dicato, M.6    Diederich, M.7
  • 148
    • 0025187312 scopus 로고
    • Is vitamin D deficiency a risk factor for prostate cancer?
    • Schwartz G, Hulka B (1990) Is vitamin D deficiency a risk factor for prostate cancer? Anticancer Res 10(5A):1307-1311
    • (1990) Anticancer Res , vol.10 , Issue.5 , pp. 1307-1311
    • Schwartz, G.1    Hulka, B.2
  • 149
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • DOI 10.1038/nature03672
    • Seligson D, Horvath S, Shi T, Yu H, Tze S, Grunstein M, Kurdistani S (2005) Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435(7046):1262-1266 (Pubitemid 40943093)
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3    Yu, H.4    Tze, S.5    Grunstein, M.6    Kurdistani, S.K.7
  • 150
    • 34250872780 scopus 로고    scopus 로고
    • Multiple molecular pathways explain the anti-proliferative effect of valproic acid on prostate cancer cells in vitro and in vivo
    • DOI 10.1002/pros.20587
    • Shabbeer S, Kortenhorst MS, Kachhap S, Galloway N, Rodriguez R, Carducci MA (2007) Multiple molecular pathways explain the anti-proliferative effect of valproic acid on prostate cancer cells in vitro and in vivo. Prostate 67(10):1099-1110 (Pubitemid 46983339)
    • (2007) Prostate , vol.67 , Issue.10 , pp. 1099-1110
    • Shabbeer, S.1    Kortenhorst, M.S.Q.2    Kachhap, S.3    Galloway, N.4    Rodriguez, R.5    Carducci, M.A.6
  • 152
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • DOI 10.1016/j.cell.2004.12.012, PII S0092867404011997
    • Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA (2004) Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119(7):941-953 (Pubitemid 40037608)
    • (2004) Cell , vol.119 , Issue.7 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3    Mulligan, P.4    Whetstine, J.R.5    Cole, P.A.6    Casero, R.A.7    Shi, Y.8
  • 153
    • 33749483782 scopus 로고    scopus 로고
    • Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo
    • DOI 10.1158/0008-5472.CAN-06-1954
    • Shukeir N, Pakneshan P, Chen G, Szyf M, Rabbani S (2006) Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo. Cancer Res 66(18):9202-9210 (Pubitemid 44521141)
    • (2006) Cancer Research , vol.66 , Issue.18 , pp. 9202-9210
    • Shukeir, N.1    Pakneshan, P.2    Chen, G.3    Szyf, M.4    Rabbani, S.A.5
  • 154
    • 0035874991 scopus 로고    scopus 로고
    • Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells
    • Singal R, van Wert J, Bashambu M (2001) Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. Cancer Res 61(12):4820-4826 (Pubitemid 32691897)
    • (2001) Cancer Research , vol.61 , Issue.12 , pp. 4820-4826
    • Singal, R.1    Van Wert, J.2    Bashambu, M.3
  • 155
    • 0035875037 scopus 로고    scopus 로고
    • Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients
    • Sozzi G, Conte D, Mariani L, Lo Vullo S, Roz L, Lombardo C, Pierotti MA, Tavecchio L (2001) Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients. Cancer Res 61(12):4675-4678 (Pubitemid 32691874)
    • (2001) Cancer Research , vol.61 , Issue.12 , pp. 4675-4678
    • Sozzi, G.1    Conte, D.2    Mariani, L.3    Lo Vullo, S.4    Roz, L.5    Lombardo, C.6    Pierotti, M.A.7    Tavecchio, L.8
  • 157
    • 0037599536 scopus 로고    scopus 로고
    • Androgen receptor involvement in the progression of prostate cancer
    • DOI 10.1677/erc.0.0100209
    • Suzuki H, Ueda T, Ichikawa T, Ito H (2003) Androgen receptor involvement in the progression of prostate cancer. Endocr Relat Cancer 10(2):209-216 (Pubitemid 36758650)
    • (2003) Endocrine-Related Cancer , vol.10 , Issue.2 , pp. 209-216
    • Suzuki, H.1    Ueda, T.2    Ichikawa, T.3    Ito, H.4
  • 158
    • 0036604404 scopus 로고    scopus 로고
    • DNA methylation in the androgen receptor gene promoter region in rat prostate cancers
    • DOI 10.1002/pros.10099
    • Takahashi S, Inaguma S, Sakakibara M, Cho YM, Suzuki S, Ikeda Y, Cui L, Shirai T (2002) DNA methylation in the androgen receptor gene promoter region in rat prostate cancers. Prostate 52(1):82-88 (Pubitemid 34553194)
    • (2002) Prostate , vol.52 , Issue.1 , pp. 82-88
    • Takahashi, S.1    Inaguma, S.2    Sakakibara, M.3    Cho, Y.-M.4    Suzuki, S.5    Ikeda, Y.6    Cui, L.7    Shirai, T.8
  • 159
    • 34247625135 scopus 로고    scopus 로고
    • Pharmacologic disruption of polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
    • DOI 10.1101/gad.1524107
    • Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET, Yu Q (2007) Pharmacologic disruption of polycombrepressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev 21(9):1050-1063 (Pubitemid 46686474)
    • (2007) Genes and Development , vol.21 , Issue.9 , pp. 1050-1063
    • Tan, J.1    Yang, X.2    Zhuang, L.3    Jiang, X.4    Chen, W.5    Puay, L.L.6    Karuturi, R.K.M.7    Tan, P.B.O.8    Liu, E.T.9    Yu, Q.10
  • 160
    • 79959315262 scopus 로고    scopus 로고
    • Detection of microRNAs in prostate cancer cells by microRNA array
    • Tang X, Gal J, Kyprianou N, Zhu H, Tang G (2011) Detection of microRNAs in prostate cancer cells by microRNA array. Methods Mol Biol 732:69-88
    • (2011) Methods Mol Biol , vol.732 , pp. 69-88
    • Tang, X.1    Gal, J.2    Kyprianou, N.3    Zhu, H.4    Tang, G.5
  • 161
    • 0034746440 scopus 로고    scopus 로고
    • Expression of RFG/ELE1α/ARA70 in normal and malignant prostatic epithelial cell cultures and lines: Regulation by methylation and sex steroids
    • DOI 10.1002/1098-2744(200101)30:1<1::AID-MC1008>3.0.CO;2-X
    • Tekur S, Lau KM, Long J, Burnstein K, Ho SM (2001) Expression of RFG/ELE1alpha/ARA70 in normal and malignant prostatic epithelial cell cultures and lines: regulation by methylation and sex steroids. Mol Carcinogen 30(1):1-13 (Pubitemid 32127345)
    • (2001) Molecular Carcinogenesis , vol.30 , Issue.1 , pp. 1-13
    • Tekur, S.1    Lau, K.-M.2    Long, J.3    Burnstein, K.4    Ho, S.-M.5
  • 162
    • 0031945210 scopus 로고    scopus 로고
    • A phase II study of 5-aza-2'deoxycytidine (decitabine) in hormone independent metastatic (D2) prostate cancer
    • Thibault A, Figg WD, Bergan RC, Lush RM, Myers CE, Tompkins A, Reed E, Samid D (1998) A phase II study of 5-aza-2′ deoxycytidine (decitabine) in hormone independent metastatic (D2) prostate cancer. Tumori 84(1):87-89 (Pubitemid 28221854)
    • (1998) Tumori , vol.84 , Issue.1 , pp. 87-89
    • Thibault, A.1    Figg, W.D.2    Bergan, R.C.3    Lush, R.M.4    Myers, C.E.5    Tompkins, A.6    Reed, E.7    Samid, D.8
  • 169
    • 0032932869 scopus 로고    scopus 로고
    • Down-regulation of CD44 expression in human prostatic carcinoma cell lines is correlated with DNA hypermethylation
    • DOI 10.1002/(SICI)1097-0215(19990129)80:3<439::AID-IJC17>3.0.CO;2-V
    • Verkaik NS, Trapman J, Romijn JC, Van der Kwast TH, Van Steenbrugge GJ (1999) Down-regulation of CD44 expression in human prostatic carcinoma cell lines is correlated with DNA hypermethylation. Int J Cancer 80(3):439-443 (Pubitemid 29019633)
    • (1999) International Journal of Cancer , vol.80 , Issue.3 , pp. 439-443
    • Verkaik, N.S.1    Trapman, J.2    Romijn, J.C.3    Van Der Kwast, T.H.4    Van Steenbrugge, G.J.5
  • 171
    • 0036604399 scopus 로고    scopus 로고
    • Silencing of π-class glutathione S-transferase in MDA PCa 2a and MDA PCa 2b cells
    • DOI 10.1002/pros.10093
    • Vidanes GM, Paton V, Wallen E, Peehl DM, Navone N, Brooks JD (2002) Silencing of pi-class glutathione S-transferase in MDA PCa 2a and MDA PCa 2b cells. Prostate 51(4):225-230 (Pubitemid 34556372)
    • (2002) Prostate , vol.51 , Issue.4 , pp. 225-230
    • Vidanes, G.M.1    Paton, V.2    Wallen, E.3    Peehl, D.M.4    Navone, N.5    Brooks, J.D.6
  • 172
    • 1542485339 scopus 로고    scopus 로고
    • Dépistage du cancer de la prostate (III) : Facteurs de risque, histoire naturelle, évolution sans traitement. Caractéristiques des cancers dépistés
    • Villers A, Soulie M, Haillot O, Boccon-Gibod L (1997) Prostate cancer screening (III): risk factors, natural history, course without treatment. Characteristics of detected cancers. Prog Urol 7 (4):655-661 (Pubitemid 127525813)
    • (1997) Progres en Urologie , vol.7 , Issue.4 , pp. 655-661
    • Villers, A.1    Soulie, M.2    Haillot, O.3    Boccon-Gibod, L.4
  • 173
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8(10):755-768
    • (2008) Nat Rev Cancer , vol.8 , Issue.10 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 177
    • 0022854396 scopus 로고
    • In vitro transformation of primary rat tracheal epithelial cells by 5-azacytidine
    • Walker C, Nettesheim P (1986) In vitro transformation of primary rat tracheal epithelial cells by 5-azacytidine. Cancer Res 46(12 Pt 1):6433-6437 (Pubitemid 17221797)
    • (1986) Cancer Research , vol.46 , Issue.12 , pp. 6433-6437
    • Walker, C.1    Nettesheim, P.2
  • 178
    • 16644369899 scopus 로고    scopus 로고
    • Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class i HDAC profiles between epithelial and stromal cells
    • Waltregny D, North B, Van Mellaert F, de Leval J, Verdin E, Castronovo V (2004) Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells. Eur J Histochem 48(3):273-290
    • (2004) Eur J Histochem , vol.48 , Issue.3 , pp. 273-290
    • Waltregny, D.1    North, B.2    Van Mellaert, F.3    De Leval, J.4    Verdin, E.5    Castronovo, V.6
  • 179
    • 31544449414 scopus 로고    scopus 로고
    • Induction of metastasis by S100P in a rat mammary model and its association with poor survival of breast cancer patients
    • DOI 10.1158/0008-5472.CAN-05-2605
    • Wang G, Platt-Higgins A, Carroll J, de Silva RS, Winstanley J, Barraclough R, Rudland P (2006) Induction of metastasis by S100P in a rat mammary model and its association with poor survival of breast cancer patients. Cancer Res 66(2):1199-1207 (Pubitemid 43165991)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 1199-1207
    • Wang, G.1    Platt-Higgins, A.2    Carroll, J.3    De Silva Rudland, S.4    Winstanley, J.5    Barraclough, R.6    Rudland, P.S.7
  • 183
    • 78649802141 scopus 로고    scopus 로고
    • Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing
    • Xu G, Wu J, Zhou L, Chen B, Sun Z, Zhao F, Tao Z (2010) Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing. PLoS One 5(11):e15519
    • (2010) PLoS One , vol.5 , Issue.11
    • Xu, G.1    Wu, J.2    Zhou, L.3    Chen, B.4    Sun, Z.5    Zhao, F.6    Tao, Z.7
  • 184
    • 33646138230 scopus 로고    scopus 로고
    • JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor
    • Yamane K, Toumazou C, Tsukada Y, Erdjument-Bromage H, Tempst P, Wong J, Zhang Y (2006) JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 125(3):483-495
    • (2006) Cell , vol.125 , Issue.3 , pp. 483-495
    • Yamane, K.1    Toumazou, C.2    Tsukada, Y.3    Erdjument-Bromage, H.4    Tempst, P.5    Wong, J.6    Zhang, Y.7
  • 188
    • 34548438593 scopus 로고    scopus 로고
    • Enhanced Therapeutic Effect on Androgen-Independent Prostate Cancer by Depsipeptide (FK228), a Histone Deacetylase Inhibitor, in Combination with Docetaxel
    • DOI 10.1016/j.urology.2007.03.052, PII S0090429507004050
    • Zhang Z, Stanfield J, Frenkel E, Kabbani W, Hsieh JT (2007) Enhanced therapeutic effect on androgen-independent prostate cancer by depsipeptide (FK228), a histone deacetylase inhibitor, in combination with docetaxel. Urology 70(2):396-401 (Pubitemid 47362245)
    • (2007) Urology , vol.70 , Issue.2 , pp. 396-401
    • Zhang, Z.1    Stanfield, J.2    Frenkel, E.3    Kabbani, W.4    Hsieh, J.-T.5
  • 189
    • 34247506661 scopus 로고    scopus 로고
    • 5-Aza-2′-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer
    • DOI 10.1158/1078-0432.CCR-06-2381
    • Zorn CS, Wojno KJ, McCabe MT, Kuefer R, Gschwend JE, Day ML (2007) 5-Aza-2′-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer. Clin Cancer Res 13(7):2136-2143 (Pubitemid 46649883)
    • (2007) Clinical Cancer Research , vol.13 , Issue.7 , pp. 2136-2143
    • Zorn, C.S.1    Wojno, K.J.2    McCabe, M.T.3    Kuefer, R.4    Gschwend, J.E.5    Day, M.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.