Aberrant methylation in promoter-associated CpG islands of multiple genes in chronic myelogenous leukemia blast crisis

Oncology Letters

Volumn 3, Issue 1, 2012, Pages 190-192

  Uehara, Eisuke ^a   Yang, Yang ^b   Fukumoto, Tetsuya ^a   Seisho, Takeuchi ^b   Matsuhashi, Yoshiko ^a   Tamura, Takahiro ^c   Matsushita, Masahide ^b   Nagai, Masami ^d   Koeffler, H Phillip ^e   Tasaka, Taizo ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b Department of Internal Medicine Kochi Medical School ^*  (India)

^c KAGAWA PREFECTURAL CENTRAL HOSPITAL   (Japan)

^d TOKUSHIMA PREFECTURAL CENTRAL HOSPITAL   (Japan)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Blast crisis; Cell cycle control genes; Chronic myelogenous leukemia; DNA repair genes; Epigenetics; Promoter hypermethylation

Indexed keywords

ACTIVATED PROTEIN C; DEATH ASSOCIATED PROTEIN KINASE; DNA; FRAGILE HISTIDINE TRIAD PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN MLH1; PROTEIN MSH2; PROTEIN P14; PROTEIN P15; PROTEIN P16; RETINOBLASTOMA PROTEIN; RETINOIC ACID RECEPTOR BETA; SUPPRESSOR OF CYTOKINE SIGNALING 1;

APOPTOSIS; ARTICLE; BASE MISPAIRING; BLAST CELL CRISIS; CANCER GROWTH; CANCER PATIENT; CELL CYCLE REGULATION; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA REPAIR; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LEUKEMOGENESIS; POLYMERASE CHAIN REACTION; PROMOTER REGION; SIGNAL TRANSDUCTION;

EID: 84855241107     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2011.419     Document Type: Article

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