-
1
-
-
84891747382
-
The machinery of macroautophagy
-
PMID: 24366339
-
Feng Y, He D, Yao Z, Klionsky DJ. The machinery of macroautophagy. Cell Res 2014; 24: 24-41; PMID: 24366339; http://dx. doi. org/10. 1038/cr. 2013. 168.
-
(2014)
Cell Res
, vol.24
, pp. 24-41
-
-
Feng, Y.1
He, D.2
Yao, Z.3
Klionsky, D.J.4
-
2
-
-
84888627184
-
Location andmembrane sources for autophagosome formation-from ER-mitochondria contact sites to Golgi-endosome-derived carriers
-
PMID: 24175710
-
Chan SN, Tang BL. Location andmembrane sources for autophagosome formation-from ER-mitochondria contact sites to Golgi-endosome-derived carriers. Mol Membr Biol 2013; 30: 394-402; PMID: 24175710; http://dx. doi. org/10. 3109/09687688. 2013. 850178.
-
(2013)
Mol Membr Biol
, vol.30
, pp. 394-402
-
-
Chan, S.N.1
Tang, B.L.2
-
3
-
-
84883452831
-
Up-to-date membrane biogenesis in the autophagosome formation
-
PMID: 23578367
-
Hamasaki M, Shibutani ST, Yoshimori T. Up-to-date membrane biogenesis in the autophagosome formation. Curr Opin Cell Biol 2013; 25: 455-60; PMID: 23578367; http://dx. doi. org/10. 1016/j. ceb. 2013. 03. 004.
-
(2013)
Curr Opin Cell Biol
, vol.25
, pp. 455-460
-
-
Hamasaki, M.1
Shibutani, S.T.2
Yoshimori, T.3
-
4
-
-
53549100450
-
Dynamics and function of PtdIns(3) P in autophagy
-
PMID: 18769109
-
ObaraK, Ohsumi, Y. Dynamics and function of PtdIns(3) P in autophagy. Autophagy 2008; 4: 952-4; PMID: 18769109; http://dx. doi. org/10. 4161/auto. 6790.
-
(2008)
Autophagy
, vol.4
, pp. 952-954
-
-
Obara, K.1
Ohsumi, Y.2
-
5
-
-
70349919804
-
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
-
PMID: 19797076
-
Simonsen A, Tooze SA. Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol 2009; 186: 773-82; PMID: 19797076; http://dx. doi. org/10. 1083/jcb. 200907014.
-
(2009)
J Cell Biol
, vol.186
, pp. 773-782
-
-
Simonsen, A.1
Tooze, S.A.2
-
6
-
-
0346503885
-
The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure
-
PMID: 14723849
-
Reggiori F, Tucker KA, Stromhaug PE, Klionsky DJ. The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 2004; 6: 79-90; PMID: 14723849; http://dx. doi. org/10. 1016/S1534-5807(03)00402-7.
-
(2004)
Dev Cell
, vol.6
, pp. 79-90
-
-
Reggiori, F.1
Tucker, K.A.2
Stromhaug, P.E.3
Klionsky, D.J.4
-
7
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
PMID: 20811354
-
Mizushima N, Levine B. Autophagy in mammalian development and differentiation. Nat Cell Biol 2010; 12: 823-30; PMID: 20811354; http://dx. doi. org/10. 1038/ncb0910-823.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
8
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
PMID: 21189453
-
Johansen T, Lamark T. Selective autophagy mediated by autophagic adapter proteins. Autophagy 2011; 7: 279-96; PMID: 21189453; http://dx. doi. org/10. 4161/auto. 7. 3. 14487.
-
(2011)
Autophagy
, vol.7
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
9
-
-
84870730914
-
Autophagic lysosome reformation
-
PMID: 22999865
-
Chen Y, Yu L. Autophagic lysosome reformation. Exp Cell Res 2012; 319: 142-6; PMID: 22999865; http://dx. doi. org/10. 1016/j. yexcr. 2012. 09. 004.
-
(2012)
Exp Cell Res
, vol.319
, pp. 142-146
-
-
Chen, Y.1
Yu, L.2
-
10
-
-
62949091373
-
Autophagy: A lysosomal degradation pathway with a central role in health and disease
-
PMID: 18706940
-
Eskelinen EL, Saftig P. Autophagy: a lysosomal degradation pathway with a central role in health and disease. Biochim Biophys Acta 2009; 1793: 664-73; PMID: 18706940; http://dx. doi. org/10. 1016/j. bbamcr. 2008. 07. 014.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 664-673
-
-
Eskelinen, E.L.1
Saftig, P.2
-
11
-
-
80052303130
-
Autophagy and aging
-
PMID: 21884931
-
Rubinsztein DC, Marino G, Kroemer G. Autophagy and aging. Cell 2011; 146: 682-95; PMID: 21884931; http://dx. doi. org/10. 1016/j. cell. 2011. 07. 030.
-
(2011)
Cell
, vol.146
, pp. 682-695
-
-
Rubinsztein, D.C.1
Marino, G.2
Kroemer, G.3
-
12
-
-
77954116814
-
Autophagy gone awry in neurodegenerative diseases
-
PMID: 20581817
-
Wong E, Cuervo AM. Autophagy gone awry in neurodegenerative diseases. Nat Neurosci 2010; 13: 805-11; PMID: 20581817; http://dx. doi. org/10. 1038/nn. 2575.
-
(2010)
Nat Neurosci
, vol.13
, pp. 805-811
-
-
Wong, E.1
Cuervo, A.M.2
-
13
-
-
84859778293
-
mTOR signaling in growth control and disease
-
PMID: 22500797
-
Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell 2012; 149: 274-93; PMID: 22500797; http://dx. doi. org/10. 1016/j. cell. 2012. 03. 017.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
14
-
-
69449087583
-
Evolution of Atg1 function and regulation
-
PMID: 19411825
-
Chan EY, Tooze, SA. Evolution of Atg1 function and regulation. Autophagy 2009; 5: 758-65; PMID: 19411825; http://dx. doi. org/10. 4161/auto. 8709.
-
(2009)
Autophagy
, vol.5
, pp. 758-765
-
-
Chan, E.Y.1
Tooze, S.A.2
-
15
-
-
45849105156
-
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
PMID: 18497260
-
Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 2008; 320: 1496-501; PMID: 18497260; http://dx. doi. org/10. 1126/science. 1157535.
-
(2008)
Science
, vol.320
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
16
-
-
77951768486
-
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
-
PMID: 20381137
-
Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 2010; 141: 290-303; PMID: 20381137; http://dx. doi. org/10. 1016/j. cell. 2010. 02. 024.
-
(2010)
Cell
, vol.141
, pp. 290-303
-
-
Sancak, Y.1
Bar-Peled, L.2
Zoncu, R.3
Markhard, A.L.4
Nada, S.5
Sabatini, D.M.6
-
17
-
-
80555143078
-
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(C)-ATPase
-
PMID: 22053050
-
Zoncu R, Bar-Peled L, Efeyan A, Wang S, Sancak Y, Sabatini DM. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(C)-ATPase. Science 2011; 334: 678-83; PMID: 22053050; http://dx. doi. org/10. 1126/science. 1207056.
-
(2011)
Science
, vol.334
, pp. 678-683
-
-
Zoncu, R.1
Bar-Peled, L.2
Efeyan, A.3
Wang, S.4
Sancak, Y.5
Sabatini, D.M.6
-
18
-
-
0038643484
-
Rheb promotes cell growth as a component of the insulin/TOR signalling network
-
PMID: 12766776
-
Saucedo LJ, Gao X, Chiarelli DA, Li L, Pan D, Edgar BA. Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nat Cell Biol 2003; 5: 566-71; PMID: 12766776; http://dx. doi. org/10. 1038/ncb996.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 566-571
-
-
Saucedo, L.J.1
Gao, X.2
Chiarelli, D.A.3
Li, L.4
Pan, D.5
Edgar, B.A.6
-
19
-
-
84875423993
-
Amino acid signalling upstream of mTOR
-
PMID: 23361334
-
Jewell JL, Russell RC, Guan KL. Amino acid signalling upstream of mTOR. Nat Rev Mol Cell Biol 2013; 14: 133-9; PMID: 23361334; http://dx. doi. org/10. 1038/nrm3522.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 133-139
-
-
Jewell, J.L.1
Russell, R.C.2
Guan, K.L.3
-
20
-
-
77950200010
-
The genetics of ageing
-
PMID: 20336132
-
Kenyon CJ. The genetics of ageing. Nature 2010; 464: 504-12; PMID: 20336132; http://dx. doi. org/10. 1038/nature08980.
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
21
-
-
0038141979
-
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
-
PMID: 12771962
-
Zhang Y, Gao X, Saucedo LJ, Ru B, Edgar BA, Pan D. Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins. Nat Cell Biol 2003; 5: 578-81; PMID: 12771962; http://dx. doi. org/10. 1038/ncb999.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 578-581
-
-
Zhang, Y.1
Gao, X.2
Saucedo, L.J.3
Ru, B.4
Edgar, B.A.5
Pan, D.6
-
22
-
-
78649348967
-
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
-
PMID: 20965424
-
Sengupta S, Peterson TR, Sabatini DM. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol Cell 2010; 40: 310-22; PMID: 20965424; http://dx. doi. org/10. 1016/j. molcel. 2010. 09. 026.
-
(2010)
Mol Cell
, vol.40
, pp. 310-322
-
-
Sengupta, S.1
Peterson, T.R.2
Sabatini, D.M.3
-
23
-
-
84891745585
-
Autophagy regulation by nutrient signaling
-
PMID: 24343578
-
Russell RC, Yuan HX, Guan KL. Autophagy regulation by nutrient signaling. Cell Res 2013; 24: 42-57; PMID: 24343578; http://dx. doi. org/10. 1038/cr. 2013. 166.
-
(2013)
Cell Res
, vol.24
, pp. 42-57
-
-
Russell, R.C.1
Yuan, H.X.2
Guan, K.L.3
-
24
-
-
84904038165
-
AMPK at the Nexus of Energetics and Aging
-
PMID: 24726383
-
Burkewitz K, Zhang Y, Mair WB. AMPK at the Nexus of Energetics and Aging. Cell Metab 2014; 20 (1): 10-25. PMID: 24726383.
-
(2014)
Cell Metab
, vol.20
, Issue.1
, pp. 10-25
-
-
Burkewitz, K.1
Zhang, Y.2
Mair, W.B.3
-
26
-
-
3142594193
-
The LKB1 tumor suppressor negatively regulates mTOR signaling
-
PMID: 15261145
-
Shaw RJ, Bardeesy N, Manning BD, Lopez L, Kosmatka M, DePinho RA, Cantley LC. The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell 2004; 6: 91-9; PMID: 15261145; http://dx. doi. org/10. 1016/j. ccr. 2004. 06. 007.
-
(2004)
Cancer Cell
, vol.6
, pp. 91-99
-
-
Shaw, R.J.1
Bardeesy, N.2
Manning, B.D.3
Lopez, L.4
Kosmatka, M.5
DePinho, R.A.6
Cantley, L.C.7
-
27
-
-
84856800302
-
Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: Cross talk, shortcuts, and feedbacks
-
PMID: 22025673
-
Alers S, Loffler AS, Wesselborg S, Stork B. Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks. Mol Cell Biol 2011; 32: 2-11; PMID: 22025673; http://dx. doi. org/10. 1128/MCB. 06159-11.
-
(2011)
Mol Cell Biol
, vol.32
, pp. 2-11
-
-
Alers, S.1
Loffler, A.S.2
Wesselborg, S.3
Stork, B.4
-
28
-
-
77955747346
-
With TOR, less is more: A key role for the conserved nutrient-sensing TOR pathway in aging
-
PMID: 20519118
-
Kapahi P, Chen D, Rogers AN, Katewa SD, Li PW, Thomas EL, Kockel L. With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab 2010; 11: 453-65; PMID: 20519118; http://dx. doi. org/10. 1016/j. cmet. 2010. 05. 001.
-
(2010)
Cell Metab
, vol.11
, pp. 453-465
-
-
Kapahi, P.1
Chen, D.2
Rogers, A.N.3
Katewa, S.D.4
Li, P.W.5
Thomas, E.L.6
Kockel, L.7
-
29
-
-
69449106873
-
Autophagy is required for extension of yeast chronological life span by rapamycin
-
PMID: 19458476
-
Alvers AL, Wood MS, Hu D, Kaywell AC, Dunn WA Jr, Aris JP. Autophagy is required for extension of yeast chronological life span by rapamycin. Autophagy 2009; 5: 847-9; PMID: 19458476; http://dx. doi. org/10. 4161/auto. 8824.
-
(2009)
Autophagy
, vol.5
, pp. 847-849
-
-
Alvers, A.L.1
Wood, M.S.2
Hu, D.3
Kaywell, A.C.4
Dunn, W.A.5
Aris, J.P.6
-
30
-
-
41449102024
-
Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans
-
PMID: 18219227
-
Toth ML, Sigmond T, Borsos E, Barna J, Erdélyi P, Takács-Vellai K, Orosz L, Kovács AL, Csikós G, Sass M, et al. Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans. Autophagy 2008; 4: 330-8; PMID: 18219227; http://dx. doi. org/10. 4161/auto. 5618.
-
(2008)
Autophagy
, vol.4
, pp. 330-338
-
-
Toth, M.L.1
Sigmond, T.2
Borsos, E.3
Barna, J.4
Erdélyi, P.5
Takács-Vellai, K.6
Orosz, L.7
Kovács, A.L.8
Csikós, G.9
Sass, M.10
-
31
-
-
40149105890
-
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans
-
Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C. A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet 2008; 4: e24; http://dx. doi. org/10. 1371/journal. pgen. 0040024.
-
(2008)
PLoS Genet
, vol.4
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
Onken, B.4
Driscoll, M.5
Kenyon, C.6
-
32
-
-
72649091698
-
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
-
PMID: 20074526
-
Bjedov I, Toivonen JM, Kerr F, Slack C, Jacobson J, Foley A, Partridge L. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metab 2010; 11: 35-46; PMID: 20074526; http://dx. doi. org/10. 1016/j. cmet. 2009. 11. 010.
-
(2010)
Cell Metab
, vol.11
, pp. 35-46
-
-
Bjedov, I.1
Toivonen, J.M.2
Kerr, F.3
Slack, C.4
Jacobson, J.5
Foley, A.6
Partridge, L.7
-
33
-
-
53549131963
-
A life-span extending form of autophagy employs the vacuolevacuole fusion machinery
-
PMID: 18690010
-
Tang F, Watkins JW, Bermudez M, Gray R, Gaban A, Portie K, Grace S, Kleve M, Craciun G. A life-span extending form of autophagy employs the vacuolevacuole fusion machinery. Autophagy 2008; 4: 874-86; PMID: 18690010; http://dx. doi. org/10. 4161/auto. 6556.
-
(2008)
Autophagy
, vol.4
, pp. 874-886
-
-
Tang, F.1
Watkins, J.W.2
Bermudez, M.3
Gray, R.4
Gaban, A.5
Portie, K.6
Grace, S.7
Kleve, M.8
Craciun, G.9
-
34
-
-
84901615928
-
Lifespan extension by methionine restriction requires autophagydependent vacuolar acidification
-
PMID: 24785424
-
Ruckenstuhl C, Netzberger C, Entfellner I, Carmona-Gutierrez D, Kickenweiz T, Stekovic S, Gleixner C, Schmid C, Klug L, Sorgo AG, et al. Lifespan extension by methionine restriction requires autophagydependent vacuolar acidification. PLoS Genet 2014; 10: e1004347; PMID: 24785424; http://dx. doi. org/10. 1371/journal. pgen. 1004347.
-
(2014)
PLoS Genet
, vol.10
-
-
Ruckenstuhl, C.1
Netzberger, C.2
Entfellner, I.3
Carmona-Gutierrez, D.4
Kickenweiz, T.5
Stekovic, S.6
Gleixner, C.7
Schmid, C.8
Klug, L.9
Sorgo, A.G.10
-
35
-
-
35848937781
-
Autophagy is required for dietary restriction-mediated life span extension in C. elegans
-
PMID: 17912023
-
Jia K, Levine B. Autophagy is required for dietary restriction-mediated life span extension in C. elegans. Autophagy 2007; 3: 597-9; PMID: 17912023; http://dx. doi. org/10. 4161/auto. 4989.
-
(2007)
Autophagy
, vol.3
, pp. 597-599
-
-
Jia, K.1
Levine, B.2
-
36
-
-
84883114523
-
Overexpression of Atg5 in mice activates autophagy and extends lifespan
-
PMID: 23939249
-
Pyo JO, Yoo SM, Ahn HH, Nah J, Hong SH, Kam TI, Jung S, Jung YK. Overexpression of Atg5 in mice activates autophagy and extends lifespan. Nat Commun 2013; 4: 2300; PMID: 23939249; http://dx. doi. org/10. 1038/ncomms3300.
-
(2013)
Nat Commun
, vol.4
, pp. 2300
-
-
Pyo, J.O.1
Yoo, S.M.2
Ahn, H.H.3
Nah, J.4
Hong, S.H.5
Kam, T.I.6
Jung, S.7
Jung, Y.K.8
-
37
-
-
38949099761
-
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
-
PMID: 18059160
-
Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD. Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy 2008; 4: 176-84; PMID: 18059160; http://dx. doi. org/10. 4161/auto. 5269.
-
(2008)
Autophagy
, vol.4
, pp. 176-184
-
-
Simonsen, A.1
Cumming, R.C.2
Brech, A.3
Isakson, P.4
Schubert, D.R.5
Finley, K.D.6
-
38
-
-
84888225099
-
Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila
-
PMID: 24244197
-
Bai H, Kang P, Hernandez AM, Tatar M. Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila. PLoS Genet 2013; 9: e1003941; PMID: 24244197; http://dx. doi. org/10. 1371/journal. pgen. 1003941.
-
(2013)
PLoS Genet
, vol.9
-
-
Bai, H.1
Kang, P.2
Hernandez, A.M.3
Tatar, M.4
-
39
-
-
84907393377
-
AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner
-
PMID: 25199830
-
Ulgherait M, Rana A, Rera M, Graniel J, Walker DW. AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner. Cell Rep 2014; 8: 1767-80; PMID: 25199830; http://dx. doi. org/10. 1016/j. celrep. 2014. 08. 006.
-
(2014)
Cell Rep
, vol.8
, pp. 1767-1780
-
-
Ulgherait, M.1
Rana, A.2
Rera, M.3
Graniel, J.4
Walker, D.W.5
-
40
-
-
78650918920
-
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
-
PMID: 21111239
-
Demontis F, Perrimon N. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 2010; 143: 813-25; PMID: 21111239; http://dx. doi. org/10. 1016/j. cell. 2010. 10. 007.
-
(2010)
Cell
, vol.143
, pp. 813-825
-
-
Demontis, F.1
Perrimon, N.2
-
41
-
-
84922545106
-
Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious aging
-
PMID: 25176656
-
Carnio S, LoVerso F, Baraibar MA, Longa E, Khan MM, Maffei M, Reischl M, Canepari M, Loefler S, Kern H, et al. Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious aging. Cell Rep 2014; 8: 1509-21; PMID: 25176656; http://dx. doi. org/10. 1016/j. celrep. 2014. 07. 061.
-
(2014)
Cell Rep
, vol.8
, pp. 1509-1521
-
-
Carnio, S.1
LoVerso, F.2
Baraibar, M.A.3
Longa, E.4
Khan, M.M.5
Maffei, M.6
Reischl, M.7
Canepari, M.8
Loefler, S.9
Kern, H.10
-
42
-
-
65549139675
-
Regulation of the aging process by autophagy
-
PMID: 19380253
-
Salminen A, Kaarniranta K. Regulation of the aging process by autophagy. Trends Mol Med 2009; 15: 217-24; PMID: 19380253; http://dx. doi. org/10. 1016/j. molmed. 2009. 03. 004.
-
(2009)
Trends Mol Med
, vol.15
, pp. 217-224
-
-
Salminen, A.1
Kaarniranta, K.2
-
43
-
-
45749114895
-
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid b accumulation in mice
-
PMID: 18497889
-
Pickford F, et al. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid b accumulation in mice. J Clin Invest 2008; 118: 2190-9; PMID: 18497889.
-
(2008)
J Clin Invest
, vol.118
, pp. 2190-2199
-
-
Pickford, F.1
-
44
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
PMID: 16625205
-
Komatsu M, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441: 880-4; PMID: 16625205; http://dx. doi. org/10. 1038/nature04723.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Masliah, E.2
Britschgi, M.3
Lucin, K.4
Narasimhan, R.5
Jaeger, P.A.6
Small, S.7
Spencer, B.8
Rockenstein, E.9
Levine, B.10
-
45
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
PMID: 16625204
-
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441: 885-9; PMID: 16625204; http://dx. doi. org/10. 1038/nature04724.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
-
46
-
-
84876812269
-
Signals from the lysosome: A control centre for cellular clearance and energy metabolism
-
PMID: 23609508
-
Settembre C, Fraldi A, Medina DL, Ballabio A. Signals from the lysosome: a control centre for cellular clearance and energy metabolism. Nat Rev Mol Cell Biol 2013; 14: 283-96; PMID: 23609508; http://dx. doi. org/10. 1038/nrm3565.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 283-296
-
-
Settembre, C.1
Fraldi, A.2
Medina, D.L.3
Ballabio, A.4
-
47
-
-
84884820652
-
Regulation of autophagy by stress-responsive transcription factors
-
PMID: 23726895
-
Pietrocola F, Izzo V, Niso-Santano M, Vacchelli E, Galluzzi L, Maiuri MC, Kroemer G. Regulation of autophagy by stress-responsive transcription factors. Semin Cancer Biol 2013; 23: 310-22; PMID: 23726895; http://dx. doi. org/10. 1016/j. semcancer. 2013. 05. 008.
-
(2013)
Semin Cancer Biol
, vol.23
, pp. 310-322
-
-
Pietrocola, F.1
Izzo, V.2
Niso-Santano, M.3
Vacchelli, E.4
Galluzzi, L.5
Maiuri, M.C.6
Kroemer, G.7
-
48
-
-
84891014899
-
The return of the nucleus: Transcriptional and epigenetic control of autophagy
-
PMID: 24326622
-
Fullgrabe J, Klionsky DJ, Joseph B. The return of the nucleus: transcriptional and epigenetic control of autophagy. Nat Rev Mol Cell Biol 2013; 15: 65-74; PMID: 24326622; http://dx. doi. org/10. 1038/nrm3716.
-
(2013)
Nat Rev Mol Cell Biol
, vol.15
, pp. 65-74
-
-
Fullgrabe, J.1
Klionsky, D.J.2
Joseph, B.3
-
49
-
-
84923031534
-
Nutrient-sensing nuclear receptors coordinate autophagy
-
Lee JM, Wagner M, Xiao R, Kim KH, Feng D, Lazar MA, Moore DD. Nutrient-sensing nuclear receptors coordinate autophagy. Nature 2014; 516(7529): 112-5.
-
(2014)
Nature
, vol.516
, Issue.7529
, pp. 112-115
-
-
Lee, J.M.1
Wagner, M.2
Xiao, R.3
Kim, K.H.4
Feng, D.5
Lazar, M.A.6
Moore, D.D.7
-
50
-
-
84922968506
-
Transcriptional regulation of autophagy by an FXR-CREB axis
-
PMID: 25383523
-
Seok S, Choi SE, Li Y, Zhu R, Kumar S, Sun X, Yoon G, Kang Y, Zhong W, Ma J, et al. Transcriptional regulation of autophagy by an FXR-CREB axis. Nature 2014; 516(7529): 108-11; PMID: 25383523.
-
(2014)
Nature
, vol.516
, Issue.7529
, pp. 108-111
-
-
Seok, S.1
Choi, S.E.2
Li, Y.3
Zhu, R.4
Kumar, S.5
Sun, X.6
Yoon, G.7
Kang, Y.8
Zhong, W.9
Ma, J.10
-
51
-
-
0033540030
-
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors
-
PMID: 10604478
-
Beck T, Hall MN. The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 1999; 402: 689-92; PMID: 10604478; http://dx. doi. org/10. 1038/45287.
-
(1999)
Nature
, vol.402
, pp. 689-692
-
-
Beck, T.1
Hall, M.N.2
-
52
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
PMID: 21617040
-
Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, et al. TFEB links autophagy to lysosomal biogenesis. Science 2011; 332: 1429-33; PMID: 21617040; http://dx. doi. org/10. 1126/science. 1204592.
-
(2011)
Science
, vol.332
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
Garcia Arencibia, M.4
Vetrini, F.5
Erdin, S.6
Erdin, S.U.7
Huynh, T.8
Medina, D.9
Colella, P.10
-
53
-
-
80052841665
-
Regulation of TFEB and V-ATPases by mTORC1
-
PMID: 21804531
-
Pena-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, Wolff NC, Tran TA, Zou L, Xie XJ, Corey DR, Brugarolas J. Regulation of TFEB and V-ATPases by mTORC1. EMBO J 2011; 30: 3242-58; PMID: 21804531; http://dx. doi. org/10. 1038/emboj. 2011. 257.
-
(2011)
EMBO J
, vol.30
, pp. 3242-3258
-
-
Pena-Llopis, S.1
Vega-Rubin-de-Celis, S.2
Schwartz, J.C.3
Wolff, N.C.4
Tran, T.A.5
Zou, L.6
Xie, X.J.7
Corey, D.R.8
Brugarolas, J.9
-
54
-
-
80655134725
-
TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes
-
PMID: 21785263
-
Settembre C, Ballabio A. TFEB regulates autophagy: an integrated coordination of cellular degradation and recycling processes. Autophagy 2011; 7: 1379-81; PMID: 21785263; http://dx. doi. org/10. 4161/auto. 7. 11. 17166.
-
(2011)
Autophagy
, vol.7
, pp. 1379-1381
-
-
Settembre, C.1
Ballabio, A.2
-
55
-
-
84857997408
-
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
-
PMID: 22343943
-
Settembre C, Zoncu R, Medina DL, Vetrini F, Erdin S, Erdin S, Huynh T, Ferron M, Karsenty G, Vellard MC, et al. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J 2012; 31: 1095-108; PMID: 22343943; http://dx. doi. org/10. 1038/emboj. 2012. 32.
-
(2012)
EMBO J
, vol.31
, pp. 1095-1108
-
-
Settembre, C.1
Zoncu, R.2
Medina, D.L.3
Vetrini, F.4
Erdin, S.5
Erdin, S.6
Huynh, T.7
Ferron, M.8
Karsenty, G.9
Vellard, M.C.10
-
56
-
-
84862539692
-
The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis
-
PMID: 22692423
-
Roczniak-Ferguson A, Petit CS, FroehlichF, Qian S, Ky J, Angarola B, Walther TC, Ferguson SM. The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Sci Signal 2012; 5: ra42; PMID: 22692423.
-
(2012)
Sci Signal
, vol.5
-
-
Roczniak-Ferguson, A.1
Petit, C.S.2
Froehlich, F.3
Qian, S.4
Ky, J.5
Angarola, B.6
Walther, T.C.7
Ferguson, S.M.8
-
57
-
-
84864874958
-
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
-
PMID: 22576015
-
Martina JA, Chen Y, Gucek M, Puertollano, R. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. Autophagy 2012; 8: 903-14; PMID: 22576015; http://dx. doi. org/10. 4161/auto. 19653.
-
(2012)
Autophagy
, vol.8
, pp. 903-914
-
-
Martina, J.A.1
Chen, Y.2
Gucek, M.3
Puertollano, R.4
-
58
-
-
67749122634
-
A gene network regulating lysosomal biogenesis and function
-
PMID: 19556463
-
Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, et al. A gene network regulating lysosomal biogenesis and function. Science 2009; 325: 473-7; PMID: 19556463.
-
(2009)
Science
, vol.325
, pp. 473-477
-
-
Sardiello, M.1
Palmieri, M.2
di Ronza, A.3
Medina, D.L.4
Valenza, M.5
Gennarino, V.A.6
Di Malta, C.7
Donaudy, F.8
Embrione, V.9
Polishchuk, R.S.10
-
59
-
-
84893055506
-
The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris
-
PMID: 24448649
-
Martina JA, Diab HI, Lishu L, Jeong-A L, Patange S, Raben N, Puertollano R. The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris. Sci Signal 2014; 7: ra9; PMID: 24448649.
-
(2014)
Sci Signal
, vol.7
-
-
Martina, J.A.1
Diab, H.I.2
Lishu, L.3
Jeong, A.L.4
Patange, S.5
Raben, N.6
Puertollano, R.7
-
60
-
-
0037007031
-
Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development
-
PMID: 11930005
-
Steingrimsson E, Tessarollo L, Pathak B, Hou L, Arnheiter H, Copeland NG, Jenkins NA. Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development. Proc Natl Acad Sci U S A 2002; 99: 4477-82; PMID: 11930005; http://dx. doi. org/10. 1073/pnas. 072071099.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 4477-4482
-
-
Steingrimsson, E.1
Tessarollo, L.2
Pathak, B.3
Hou, L.4
Arnheiter, H.5
Copeland, N.G.6
Jenkins, N.A.7
-
61
-
-
0032414526
-
The bHLH-Zip transcription factor Tfeb is essential for placental vascularization
-
PMID: 9806910
-
Steingrimsson E, Tessarollo L, Reid SW, Jenkins NA, Copeland NG. The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. Development 1998; 125: 4607-16; PMID: 9806910.
-
(1998)
Development
, vol.125
, pp. 4607-4616
-
-
Steingrimsson, E.1
Tessarollo, L.2
Reid, S.W.3
Jenkins, N.A.4
Copeland, N.G.5
-
62
-
-
84886871016
-
Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases
-
PMID: 24081491
-
Petit CS, Roczniak-Ferguson A, Ferguson SM. Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases. J Cell Biol 2013; 202: 1107-22; PMID: 24081491; http://dx. doi. org/10. 1083/jcb. 201307084.
-
(2013)
J Cell Biol
, vol.202
, pp. 1107-1122
-
-
Petit, C.S.1
Roczniak-Ferguson, A.2
Ferguson, S.M.3
-
63
-
-
84888200442
-
The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1
-
PMID: 24095279
-
Tsun ZY, Bar-Peled L, Chantranupong L, Zoncu R, Wang T, Kim C, Spooner E, Sabatini DM. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1. Mol Cell 2013; 52: 495-505; PMID: 24095279; http://dx. doi. org/10. 1016/j. molcel. 2013. 09. 016.
-
(2013)
Mol Cell
, vol.52
, pp. 495-505
-
-
Tsun, Z.Y.1
Bar-Peled, L.2
Chantranupong, L.3
Zoncu, R.4
Wang, T.5
Kim, C.6
Spooner, E.7
Sabatini, D.M.8
-
64
-
-
84883063789
-
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans
-
PMID: 23925298
-
Lapierre LR, De Magalhaes Filho CD, McQuary PR, Chu CC, Visvikis O, Chang JT, Gelino S, Ong B, Davis AE, Irazoqui JE, et al. The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans. Nat Commun 2013; 4: 2267; PMID: 23925298.
-
(2013)
Nat Commun
, vol.4
-
-
Lapierre, L.R.1
De Magalhaes Filho, C.D.2
McQuary, P.R.3
Chu, C.C.4
Visvikis, O.5
Chang, J.T.6
Gelino, S.7
Ong, B.8
Davis, A.E.9
Irazoqui, J.E.10
-
65
-
-
84878606239
-
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
-
PMID: 23604321
-
Settembre C, De Cegli R, Mansueto G, Saha PK, Vetrini F, Visvikis O, Huynh T, Carissimo A, Palmer D, Klisch TJ, et al. TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop. Nat Cell Biol 2013; 15: 647-58; PMID: 23604321; http://dx. doi. org/10. 1038/ncb2718.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 647-658
-
-
Settembre, C.1
De Cegli, R.2
Mansueto, G.3
Saha, P.K.4
Vetrini, F.5
Visvikis, O.6
Huynh, T.7
Carissimo, A.8
Palmer, D.9
Klisch, T.J.10
-
66
-
-
84869488061
-
Lessons from C. elegans: Signaling pathways for longevity
-
PMID: 22939742
-
Lapierre LR, Hansen M. Lessons from C. elegans: signaling pathways for longevity. Trends Endocrinol Metab 2012; 23: 637-44; PMID: 22939742; http://dx. doi. org/10. 1016/j. tem. 2012. 07. 007.
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 637-644
-
-
Lapierre, L.R.1
Hansen, M.2
-
67
-
-
84878533962
-
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
-
PMID: 23604316
-
O'Rourke EJ, Ruvkun G. MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability. Nat Cell Biol 2013; 15: 668-76; PMID: 23604316; http://dx. doi. org/10. 1038/ncb2741.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 668-676
-
-
O'Rourke, E.J.1
Ruvkun, G.2
-
68
-
-
84876090708
-
ZKSCAN3 is a master transcriptional repressor of autophagy
-
PMID: 23434374
-
Chauhan S, Goodwin JG, Chauhan S, Manyam G, Wang J, Kamat AM, Boyd DD. ZKSCAN3 is a master transcriptional repressor of autophagy. Mol Cell 2013; 50: 16-28; PMID: 23434374; http://dx. doi. org/10. 1016/j. molcel. 2013. 01. 024.
-
(2013)
Mol Cell
, vol.50
, pp. 16-28
-
-
Chauhan, S.1
Goodwin, J.G.2
Chauhan, S.3
Manyam, G.4
Wang, J.5
Kamat, A.M.6
Boyd, D.D.7
-
69
-
-
55849101681
-
Fat metabolism links germline stem cells and longevity in C. elegans
-
PMID: 18988854
-
Wang MC, O'Rourke EJ, Ruvkun G. Fat metabolism links germline stem cells and longevity in C. elegans. Science 2008; 322: 957-60; PMID: 18988854; http://dx. doi. org/10. 1126/science. 1162011.
-
(2008)
Science
, vol.322
, pp. 957-960
-
-
Wang, M.C.1
O'Rourke, E.J.2
Ruvkun, G.3
-
70
-
-
80053312481
-
Autophagy and lipid metabolism coordinately modulate aging in germline-less C. elegans
-
PMID: 21906946
-
Lapierre LR, Gelino SR, Melendez A, Hansen M. Autophagy and lipid metabolism coordinately modulate aging in germline-less C. elegans. Curr Biol 2011; 21: 1507-1514; PMID: 21906946; http://dx. doi. org/10. 1016/j. cub. 2011. 07. 042.
-
(2011)
Curr Biol
, vol.21
, pp. 1507-1514
-
-
Lapierre, L.R.1
Gelino, S.R.2
Melendez, A.3
Hansen, M.4
-
71
-
-
84923285482
-
Lysosome: Regulator of lipid degradation pathways
-
PMID: 25061009
-
Settembre C, Ballabio A. Lysosome: regulator of lipid degradation pathways. Trends Cell Biol 2014; 24 (12): 743-50; PMID: 25061009.
-
(2014)
Trends Cell Biol
, vol.24
, Issue.12
, pp. 743-750
-
-
Settembre, C.1
Ballabio, A.2
-
72
-
-
84874712704
-
Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in a-1-antitrypsin deficiency
-
PMID: 23381957
-
Pastore N, Blomenkamp K, Annunziata F, Piccolo P, Mithbaokar P, Maria Sepe R, Vetrini F, Palmer D, Ng P, Polishchuk E, et al. Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in a-1-antitrypsin deficiency. EMBO Mol Med 2013; 5: 397-412; PMID: 23381957; http://dx. doi. org/10. 1002/emmm. 201202046.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 397-412
-
-
Pastore, N.1
Blomenkamp, K.2
Annunziata, F.3
Piccolo, P.4
Mithbaokar, P.5
Maria Sepe, R.6
Vetrini, F.7
Palmer, D.8
Ng, P.9
Polishchuk, E.10
-
73
-
-
80052729465
-
Transcriptional activation of lysosomal exocytosis promotes cellular clearance
-
PMID: 21889421
-
Medina DL, Fraldi A, Bouche V, Annunziata F, Mansueto G, Spampanato C, Puri C, Pignata A, Martina JA, Sardiello M, et al. Transcriptional activation of lysosomal exocytosis promotes cellular clearance. Dev Cell 2011; 21: 421-30; PMID: 21889421; http://dx. doi. org/10. 1016/j. devcel. 2011. 07. 016.
-
(2011)
Dev Cell
, vol.21
, pp. 421-430
-
-
Medina, D.L.1
Fraldi, A.2
Bouche, V.3
Annunziata, F.4
Mansueto, G.5
Spampanato, C.6
Puri, C.7
Pignata, A.8
Martina, J.A.9
Sardiello, M.10
-
74
-
-
84916928995
-
Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
-
PMID: 25069841
-
Polito VA, Li H, Martini-Stoica H, Wang B, Yang L, Xu Y, Swartzlander DB, Palmieri M, di Ronza A, Lee VM, et al. Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB. EMBO Mol Med 2014; 6(9): 1142-60; PMID: 25069841.
-
(2014)
EMBO Mol Med
, vol.6
, Issue.9
, pp. 1142-1160
-
-
Polito, V.A.1
Li, H.2
Martini-Stoica, H.3
Wang, B.4
Yang, L.5
Xu, Y.6
Swartzlander, D.B.7
Palmieri, M.8
di Ronza, A.9
Lee, V.M.10
-
75
-
-
84863923855
-
PGC-1alpha rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function
-
PMID: 22786682
-
Tsunemi T, Ashe TD, Morrison BE, Soriano KR, Au J, Roque RA, Lazarowski ER, Damian VA, Masliah E, La Spada AR. PGC-1alpha rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function. Sci Transl Med 2012; 4: 142ra97; PMID: 22786682; http://dx. doi. org/10. 1126/scitranslmed. 3003799.
-
(2012)
Sci Transl Med
, vol.4
, pp. 142ra97
-
-
Tsunemi, T.1
Ashe, T.D.2
Morrison, B.E.3
Soriano, K.R.4
Au, J.5
Roque, R.A.6
Lazarowski, E.R.7
Damian, V.A.8
Masliah, E.9
La Spada, A.R.10
-
76
-
-
80455143200
-
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
-
PMID: 22055505
-
Rera M, Bahadorani S, Cho J, Koehler CL, Ulgherait M, Hur JH, Ansari WS, Lo T Jr, Jones DL, Walker DW. Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. Cell Metab 2011; 14: 623-34; PMID: 22055505; http://dx. doi. org/10. 1016/j. cmet. 2011. 09. 013.
-
(2011)
Cell Metab
, vol.14
, pp. 623-634
-
-
Rera, M.1
Bahadorani, S.2
Cho, J.3
Koehler, C.L.4
Ulgherait, M.5
Hur, J.H.6
Ansari, W.S.7
Lo, T.8
Jones, D.L.9
Walker, D.W.10
-
77
-
-
84906674973
-
Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA
-
PMID: 25108912
-
Cortes CJ, Miranda HC, Frankowski H, Batlevi Y, Young JE, Le A, Ivanov N, Sopher BL, Carromeu C, Muotri AR, et al. Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. Nat Neurosci 2014; 17(9): 1180-9; PMID: 25108912.
-
(2014)
Nat Neurosci
, vol.17
, Issue.9
, pp. 1180-1189
-
-
Cortes, C.J.1
Miranda, H.C.2
Frankowski, H.3
Batlevi, Y.4
Young, J.E.5
Le, A.6
Ivanov, N.7
Sopher, B.L.8
Carromeu, C.9
Muotri, A.R.10
-
78
-
-
84902658412
-
Innate Host Defense Requires TFEBMediated Transcription of Cytoprotective and Antimicrobial Genes
-
PMID: 24882217
-
Visvikis O, Ihuegbu N, Labed SA, Luhachack LG, Alves AM, Wollenberg AC, Stuart LM, Stormo GD, Irazoqui JE. Innate Host Defense Requires TFEBMediated Transcription of Cytoprotective and Antimicrobial Genes. Immunity 2014; 40(6): 896-909; PMID: 24882217.
-
(2014)
Immunity
, vol.40
, Issue.6
, pp. 896-909
-
-
Visvikis, O.1
Ihuegbu, N.2
Labed, S.A.3
Luhachack, L.G.4
Alves, A.M.5
Wollenberg, A.C.6
Stuart, L.M.7
Stormo, G.D.8
Irazoqui, J.E.9
-
79
-
-
84864882073
-
FOXOphagy path to inducing stress resistance and cell survival
-
PMID: 22854812
-
Sandri M. FOXOphagy path to inducing stress resistance and cell survival. Nat Cell Biol 2012; 14: 786-8; PMID: 22854812; http://dx. doi. org/10. 1038/ncb2550.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 786-788
-
-
Sandri, M.1
-
80
-
-
36448968532
-
FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
-
PMID: 18054316
-
Zhao J, Brault JJ, Schild A, Cao P, Sandri M, Schiaffino S, Lecker SH, Goldberg AL. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 2007; 6: 472-83; PMID: 18054316; http://dx. doi. org/10. 1016/j. cmet. 2007. 11. 004.
-
(2007)
Cell Metab
, vol.6
, pp. 472-483
-
-
Zhao, J.1
Brault, J.J.2
Schild, A.3
Cao, P.4
Sandri, M.5
Schiaffino, S.6
Lecker, S.H.7
Goldberg, A.L.8
-
81
-
-
36448940798
-
FoxO3 controls autophagy in skeletal muscle in vivo
-
PMID: 18054315
-
Mammucari C, Milan G, Romanello V, Masiero E, Rudolf R, Del Piccolo P, Burden SJ, Di Lisi R, Sandri C, Zhao J, et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 2007; 6: 458-71; PMID: 18054315; http://dx. doi. org/10. 1016/j. cmet. 2007. 11. 001.
-
(2007)
Cell Metab
, vol.6
, pp. 458-471
-
-
Mammucari, C.1
Milan, G.2
Romanello, V.3
Masiero, E.4
Rudolf, R.5
Del Piccolo, P.6
Burden, S.J.7
Di Lisi, R.8
Sandri, C.9
Zhao, J.10
-
82
-
-
84885174647
-
Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome
-
PMID: 23665154
-
Sandri M. Protein breakdown in muscle wasting: role of autophagy-lysosome and ubiquitin-proteasome. Int J Biochem Cell Biol 2013; 45: 2121-9; PMID: 23665154; http://dx. doi. org/10. 1016/j. biocel. 2013. 04. 023.
-
(2013)
Int J Biochem Cell Biol
, vol.45
, pp. 2121-2129
-
-
Sandri, M.1
-
83
-
-
43949109275
-
Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle
-
PMID: 18367868
-
Mammucari C, Schiaffino S, Sandri M. Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle. Autophagy 2008; 4: 524-6; PMID: 18367868; http://dx. doi. org/10. 4161/auto. 5905.
-
(2008)
Autophagy
, vol.4
, pp. 524-526
-
-
Mammucari, C.1
Schiaffino, S.2
Sandri, M.3
-
84
-
-
70350500068
-
FoxO transcription factors promote autophagy in cardiomyocytes
-
PMID: 19696026
-
Sengupta A, Molkentin JD, Yutzey KE. FoxO transcription factors promote autophagy in cardiomyocytes. J Biol Chem 2009; 284: 28319-31; PMID: 19696026; http://dx. doi. org/10. 1074/jbc. M109. 024406.
-
(2009)
J Biol Chem
, vol.284
, pp. 28319-28331
-
-
Sengupta, A.1
Molkentin, J.D.2
Yutzey, K.E.3
-
85
-
-
41449113346
-
Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor
-
PMID: 18227643
-
Zhao J, Brault JJ, Schild A, Goldberg, AL. Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor. Autophagy 2008; 4: 378-80; PMID: 18227643; http://dx. doi. org/10. 4161/auto. 5633.
-
(2008)
Autophagy
, vol.4
, pp. 378-380
-
-
Zhao, J.1
Brault, J.J.2
Schild, A.3
Goldberg, A.L.4
-
86
-
-
84899450195
-
FoxO transcription factors: Their roles in the maintenance of skeletal muscle homeostasis
-
Sanchez AM, Candau RB, Bernardi H. FoxO transcription factors: their roles in the maintenance of skeletal muscle homeostasis. Cell Mol Life Sci 2013; 71(9): 1657-71.
-
(2013)
Cell Mol Life Sci
, vol.71
, Issue.9
, pp. 1657-1671
-
-
Sanchez, A.M.1
Candau, R.B.2
Bernardi, H.3
-
87
-
-
41849128523
-
The FoxO code
-
PMID: 18391970
-
Calnan DR, Brunet A. The FoxO code. Oncogene 2008; 27: 2276-88; PMID: 18391970; http://dx. doi. org/10. 1038/onc. 2008. 21.
-
(2008)
Oncogene
, vol.27
, pp. 2276-2288
-
-
Calnan, D.R.1
Brunet, A.2
-
88
-
-
34848850156
-
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
-
PMID: 17900900
-
Greer EL, Dowlatshahi D, Banko MR, Villen J, Hoang K, Blanchard D, Gygi SP, Brunet A. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr Biol 2007; 17: 1646-56; PMID: 17900900; http://dx. doi. org/10. 1016/j. cub. 2007. 08. 047.
-
(2007)
Curr Biol
, vol.17
, pp. 1646-1656
-
-
Greer, E.L.1
Dowlatshahi, D.2
Banko, M.R.3
Villen, J.4
Hoang, K.5
Blanchard, D.6
Gygi, S.P.7
Brunet, A.8
-
89
-
-
34848861463
-
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
-
PMID: 17711846
-
Greer EL, Oskoui PR, Banko MR, Maniar JM, Gygi MP, Gygi SP, Brunet A. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem 2007; 282: 30107-19; PMID: 17711846; http://dx. doi. org/10. 1074/jbc. M705325200.
-
(2007)
J Biol Chem
, vol.282
, pp. 30107-30119
-
-
Greer, E.L.1
Oskoui, P.R.2
Banko, M.R.3
Maniar, J.M.4
Gygi, M.P.5
Gygi, S.P.6
Brunet, A.7
-
90
-
-
77952586060
-
Mitochondrial fission and remodelling contributes to muscle atrophy
-
PMID: 20400940
-
Romanello V, Guadagnin E, Gomes L, Roder I, Sandri C, Petersen Y, Milan G, Masiero E, Del Piccolo P, Foretz M, et al. Mitochondrial fission and remodelling contributes to muscle atrophy. EMBO J 2010; 29: 1774-85; PMID: 20400940; http://dx. doi. org/10. 1038/emboj. 2010. 60.
-
(2010)
EMBO J
, vol.29
, pp. 1774-1785
-
-
Romanello, V.1
Guadagnin, E.2
Gomes, L.3
Roder, I.4
Sandri, C.5
Petersen, Y.6
Milan, G.7
Masiero, E.8
Del Piccolo, P.9
Foretz, M.10
-
91
-
-
84862082711
-
Modulation of autophagy and ubiquitin-proteasome pathways during ultra-endurance running
-
PMID: 22345427
-
Jamart C, Francaux M, Millet GY, Deldicque L, Frére D, Féasson L. Modulation of autophagy and ubiquitin-proteasome pathways during ultra-endurance running. J Appl Physiol (1985) 2012; 112: 1529-37; PMID: 22345427; http://dx. doi. org/10. 1152/japplphysiol. 00952. 2011.
-
(2012)
J Appl Physiol (1985)
, vol.112
, pp. 1529-1537
-
-
Jamart, C.1
Francaux, M.2
Millet, G.Y.3
Deldicque, L.4
Frére, D.5
Féasson, L.6
-
92
-
-
33751430460
-
The search for DAF-16/FOXO transcriptional targets: Approaches and discoveries
-
PMID: 16934425
-
Murphy CT. The search for DAF-16/FOXO transcriptional targets: approaches and discoveries. Exp Gerontol 2006; 41: 910-21; PMID: 16934425; http://dx. doi. org/10. 1016/j. exger. 2006. 06. 040.
-
(2006)
Exp Gerontol
, vol.41
, pp. 910-921
-
-
Murphy, C.T.1
-
93
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
PMID: 12845331
-
Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 2003; 424: 277-83; PMID: 12845331; http://dx. doi. org/10. 1038/nature01789.
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
Li, H.7
Kenyon, C.8
-
94
-
-
77956334156
-
Insulinlike signaling determines survival during stress via posttranscriptional mechanisms in C. elegans
-
PMID: 20816092
-
McColl G, Rogers AN, Alavez S, Hubbard AE, Melov S, Link CD, Bush AI, Kapahi P, Lithgow GJ. Insulinlike signaling determines survival during stress via posttranscriptional mechanisms in C. elegans. Cell Metab 2010; 12: 260-72; PMID: 20816092; http://dx. doi. org/10. 1016/j. cmet. 2010. 08. 004.
-
(2010)
Cell Metab
, vol.12
, pp. 260-272
-
-
McColl, G.1
Rogers, A.N.2
Alavez, S.3
Hubbard, A.E.4
Melov, S.5
Link, C.D.6
Bush, A.I.7
Kapahi, P.8
Lithgow, G.J.9
-
95
-
-
70149085849
-
Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance
-
PMID: 19667176
-
Jia K, Thomas C, Akbar M, Sun Q, Adams-Huet B, Gilpin C, Levine B. Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance. Proc Natl Acad Sci U S A 2009; 106: 14564-9; PMID: 19667176; http://dx. doi. org/10. 1073/pnas. 0813319106.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14564-14569
-
-
Jia, K.1
Thomas, C.2
Akbar, M.3
Sun, Q.4
Adams-Huet, B.5
Gilpin, C.6
Levine, B.7
-
96
-
-
77649225979
-
Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response
-
PMID: 20174564
-
Zhong M, NiuW, Lu ZJ, Sarov M, Murray JI, Janette J, Raha D, Sheaffer KL, Lam HY, Preston E, et al. Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response. PLoS Genet 2010; 6: e1000848; PMID: 20174564; http://dx. doi. org/10. 1371/journal. pgen. 1000848.
-
(2010)
PLoS Genet
, vol.6
-
-
Zhong, M.1
Niu, W.2
Lu, Z.J.3
Sarov, M.4
Murray, J.I.5
Janette, J.6
Raha, D.7
Sheaffer, K.L.8
Lam, H.Y.9
Preston, E.10
-
97
-
-
79551614016
-
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans
-
PMID: 21177963
-
Niu W, Lu ZJ, Zhong M, Sarov M, Murray JI, Brdlik CM, Janette J, Chen C, Alves P, Preston E, et al. Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans. Genome Res 2010; 21: 245-54; PMID: 21177963; http://dx. doi. org/10. 1101/gr. 114587. 110.
-
(2010)
Genome Res
, vol.21
, pp. 245-254
-
-
Niu, W.1
Lu, Z.J.2
Zhong, M.3
Sarov, M.4
Murray, J.I.5
Brdlik, C.M.6
Janette, J.7
Chen, C.8
Alves, P.9
Preston, E.10
-
98
-
-
34249888736
-
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
-
PMID: 17476212
-
Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 2007; 447: 550-5; PMID: 17476212; http://dx. doi. org/10. 1038/nature05837.
-
(2007)
Nature
, vol.447
, pp. 550-555
-
-
Panowski, S.H.1
Wolff, S.2
Aguilaniu, H.3
Durieux, J.4
Dillin, A.5
-
99
-
-
52049093450
-
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging
-
PMID: 18804378
-
Sheaffer KL, Updike DL, Mango SE. The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging. Curr Biol 2008; 18: 1355-64; PMID: 18804378; http://dx. doi. org/10. 1016/j. cub. 2008. 07. 097.
-
(2008)
Curr Biol
, vol.18
, pp. 1355-1364
-
-
Sheaffer, K.L.1
Updike, D.L.2
Mango, S.E.3
-
100
-
-
84860461929
-
TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO
-
PMID: 22560223
-
Robida-Stubbs S, Glover-Cutter K, Lamming DW, Mizunuma M, Narasimhan SD, Neumann-Haefelin E, Sabatini DM, Blackwell TK. TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO. Cell Metab 2012; 15: 713-24; PMID: 22560223; http://dx. doi. org/10. 1016/j. cmet. 2012. 04. 007.
-
(2012)
Cell Metab
, vol.15
, pp. 713-724
-
-
Robida-Stubbs, S.1
Glover-Cutter, K.2
Lamming, D.W.3
Mizunuma, M.4
Narasimhan, S.D.5
Neumann-Haefelin, E.6
Sabatini, D.M.7
Blackwell, T.K.8
-
101
-
-
84865656107
-
Regulation of autophagy by Forkhead box (FOX) O transcription factors
-
PMID: 22115564
-
van der Vos KE, Gomez-Puerto C, Coffer PJ. Regulation of autophagy by Forkhead box (FOX) O transcription factors. Adv Biol Regul 2012; 52: 122-36; PMID: 22115564; http://dx. doi. org/10. 1016/j. advenzreg. 2011. 10. 002.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 122-136
-
-
van der Vos, K.E.1
Gomez-Puerto, C.2
Coffer, P.J.3
-
102
-
-
84872143888
-
Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: Roles for GATA factors and lipid gene regulators
-
PMID: 23312285
-
Zhang P, Judy M, Lee SJ, Kenyon C. Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators. Cell Metab 2013; 17: 85-100; PMID: 23312285; http://dx. doi. org/10. 1016/j. cmet. 2012. 12. 013.
-
(2013)
Cell Metab
, vol.17
, pp. 85-100
-
-
Zhang, P.1
Judy, M.2
Lee, S.J.3
Kenyon, C.4
-
103
-
-
84866182143
-
RPN-6 determines C. elegans longevity under proteotoxic stress conditions
-
PMID: 22922647
-
Vilchez D, Morantte I, Liu Z, Douglas PM, Merkwirth C, Rodrigues AP, Manning G, Dillin A. RPN-6 determines C. elegans longevity under proteotoxic stress conditions. Nature 2012; 489: 263-8; PMID: 22922647; http://dx. doi. org/10. 1038/nature11315.
-
(2012)
Nature
, vol.489
, pp. 263-268
-
-
Vilchez, D.1
Morantte, I.2
Liu, Z.3
Douglas, P.M.4
Merkwirth, C.5
Rodrigues, A.P.6
Manning, G.7
Dillin, A.8
-
104
-
-
77956795163
-
Widespread protein aggregation as an inherent part of aging in C. elegans
-
PMID: 20711477
-
David DC, Ollikainen N, Trinidad JC, Cary MP, Burlingame AL, Kenyon C. Widespread protein aggregation as an inherent part of aging in C. elegans. PLoS Biol 2010; 8: e1000450; PMID: 20711477; http://dx. doi. org/10. 1371/journal. pbio. 1000450.
-
(2010)
PLoS Biol
, vol.8
-
-
David, D.C.1
Ollikainen, N.2
Trinidad, J.C.3
Cary, M.P.4
Burlingame, A.L.5
Kenyon, C.6
-
105
-
-
70349266064
-
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
-
PMID: 19706382
-
Ben-Zvi A, Miller EA, Morimoto RI. Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc Natl Acad Sci U S A 2009; 106: 14914-9; PMID: 19706382; http://dx. doi. org/10. 1073/pnas. 0902882106.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14914-14919
-
-
Ben-Zvi, A.1
Miller, E.A.2
Morimoto, R.I.3
-
106
-
-
80052382925
-
Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation
-
PMID: 21552009
-
Mortensen M, Watson AS, Simon AK. Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation. Autophagy 2011; 7: 1069-70; PMID: 21552009; http://dx. doi. org/10. 4161/auto. 7. 9. 15886.
-
(2011)
Autophagy
, vol.7
, pp. 1069-1070
-
-
Mortensen, M.1
Watson, A.S.2
Simon, A.K.3
-
107
-
-
84866167976
-
Increased proteasome activity in human embryonic stem cells is regulated by PSMD11
-
PMID: 22972301
-
Vilchez D, Boyer L, Morantte I, Lutz M, Merkwirth C, Joyce D, Spencer B, Page L, Masliah E, Berggren WT, et al. Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature 2012; 489: 304-8; PMID: 22972301; http://dx. doi. org/10. 1038/nature11468.
-
(2012)
Nature
, vol.489
, pp. 304-308
-
-
Vilchez, D.1
Boyer, L.2
Morantte, I.3
Lutz, M.4
Merkwirth, C.5
Joyce, D.6
Spencer, B.7
Page, L.8
Masliah, E.9
Berggren, W.T.10
-
108
-
-
67649491263
-
A soma-togermline transformation in long-lived Caenorhabditis elegans mutants
-
PMID: 19506556
-
Curran SP, Wu X, Riedel CG, Ruvkun G. A soma-togermline transformation in long-lived Caenorhabditis elegans mutants. Nature 2009; 459: 1079-84; PMID: 19506556; http://dx. doi. org/10. 1038/nature08106.
-
(2009)
Nature
, vol.459
, pp. 1079-1084
-
-
Curran, S.P.1
Wu, X.2
Riedel, C.G.3
Ruvkun, G.4
-
109
-
-
84898438267
-
Cracking the survival code: Autophagy-related histone modifications
-
PMID: 24429873
-
Fullgrabe J, Heldring N, Hermanson O, Joseph B. Cracking the survival code: Autophagy-related histone modifications. Autophagy 2014; 10: 556-561; PMID: 24429873; http://dx. doi. org/10. 4161/auto. 27280.
-
(2014)
Autophagy
, vol.10
, pp. 556-561
-
-
Fullgrabe, J.1
Heldring, N.2
Hermanson, O.3
Joseph, B.4
-
110
-
-
84902280610
-
Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response
-
PMID: 24814484
-
Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, et al. Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response. Cell Metab 2014; 19: 952-66; PMID: 24814484; http://dx. doi. org/10. 1016/j. cmet. 2014. 04. 004.
-
(2014)
Cell Metab
, vol.19
, pp. 952-966
-
-
Dang, W.1
Sutphin, G.L.2
Dorsey, J.A.3
Otte, G.L.4
Cao, K.5
Perry, R.M.6
Wanat, J.J.7
Saviolaki, D.8
Murakami, C.J.9
Tsuchiyama, S.10
-
111
-
-
84877309346
-
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
-
PMID: 23604319
-
Riedel CG, Dowen RH, Lourenco GF, Kirienko NV, Heimbucher T, West JA, Bowman SK, Kingston RE, Dillin A, Asara JM, et al. DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity. Nat Cell Biol 2013; 15: 491-501; PMID: 23604319; http://dx. doi. org/10. 1038/ncb2720.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 491-501
-
-
Riedel, C.G.1
Dowen, R.H.2
Lourenco, G.F.3
Kirienko, N.V.4
Heimbucher, T.5
West, J.A.6
Bowman, S.K.7
Kingston, R.E.8
Dillin, A.9
Asara, J.M.10
-
112
-
-
84896739647
-
Small molecule SIRT1 activators for the treatment of aging and age-related diseases
-
PMID: 24439680
-
Hubbard BP, Sinclair DA. Small molecule SIRT1 activators for the treatment of aging and age-related diseases. Trends Pharmacol Sci 2014; 35: 146-54; PMID: 24439680; http://dx. doi. org/10. 1016/j. tips. 2013. 12. 004.
-
(2014)
Trends Pharmacol Sci
, vol.35
, pp. 146-154
-
-
Hubbard, B.P.1
Sinclair, D.A.2
-
113
-
-
84894489242
-
Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction
-
PMID: 23661364
-
Park S, Mori R, Shimokawa I. Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction. Mol Cells 2013; 35: 474-80; PMID: 23661364; http://dx. doi. org/10. 1007/s10059-013-0130-x.
-
(2013)
Mol Cells
, vol.35
, pp. 474-480
-
-
Park, S.1
Mori, R.2
Shimokawa, I.3
-
114
-
-
84903451392
-
Sirtuins: Guardians of mammalian healthspan
-
PMID: 24877878
-
Giblin W, Skinner ME, Lombard DB. Sirtuins: guardians of mammalian healthspan. Trends Genet 2014; 30(7): 271-86; PMID: 24877878.
-
(2014)
Trends Genet
, vol.30
, Issue.7
, pp. 271-286
-
-
Giblin, W.1
Skinner, M.E.2
Lombard, D.B.3
-
115
-
-
79953043473
-
Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
-
PMID: 21364612
-
Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, Criollo A, Galluzzi L, Malik SA, Vitale I, et al. Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. Cell Death Dis 2010; 1: e10; PMID: 21364612; http://dx. doi. org/10. 1038/cddis. 2009. 8.
-
(2010)
Cell Death Dis
, vol.1
-
-
Morselli, E.1
Maiuri, M.C.2
Markaki, M.3
Megalou, E.4
Pasparaki, A.5
Palikaras, K.6
Criollo, A.7
Galluzzi, L.8
Malik, S.A.9
Vitale, I.10
-
116
-
-
75149128169
-
The life span-prolonging effect of sirtuin-1 is mediated by autophagy
-
PMID: 20023410
-
Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, Criollo A, Galluzzi L, Malik SA, Vitale I, et al. The life span-prolonging effect of sirtuin-1 is mediated by autophagy. Autophagy 2010; 6: 186-8; PMID: 20023410; http://dx. doi. org/10. 4161/auto. 6. 1. 10817.
-
(2010)
Autophagy
, vol.6
, pp. 186-188
-
-
Morselli, E.1
Maiuri, M.C.2
Markaki, M.3
Megalou, E.4
Pasparaki, A.5
Palikaras, K.6
Criollo, A.7
Galluzzi, L.8
Malik, S.A.9
Vitale, I.10
-
117
-
-
67349273985
-
SIRT1: Regulation of longevity via autophagy
-
PMID: 19249351
-
Salminen A, Kaarniranta K. SIRT1: regulation of longevity via autophagy. Cell Signal 2009; 21: 1356-60; PMID: 19249351; http://dx. doi. org/10. 1016/j. cellsig. 2009. 02. 014.
-
(2009)
Cell Signal
, vol.21
, pp. 1356-1360
-
-
Salminen, A.1
Kaarniranta, K.2
-
118
-
-
84882846112
-
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
-
PMID: 23863932
-
Fullgrabe J, Lynch-Day MA, Heldring N, Li W, Struijk RB, Ma Q, Hermanson O, Rosenfeld MG, Klionsky DJ, Joseph B. The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy. Nature 2013; 500: 468-71; PMID: 23863932; http://dx. doi. org/10. 1038/nature12313.
-
(2013)
Nature
, vol.500
, pp. 468-471
-
-
Fullgrabe, J.1
Lynch-Day, M.A.2
Heldring, N.3
Li, W.4
Struijk, R.B.5
Ma, Q.6
Hermanson, O.7
Rosenfeld, M.G.8
Klionsky, D.J.9
Joseph, B.10
-
119
-
-
79951889242
-
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
-
PMID: 21339330
-
Morselli E, Mariño G, Bennetzen MV, Eisenberg T, Megalou E, Schroeder S, Cabrera S, Bénit P, Rustin P, Criollo A, et al. Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome. J Cell Biol 2011; 192; 615-29; PMID: 21339330; http://dx. doi. org/10. 1083/jcb. 201008167.
-
(2011)
J Cell Biol
, vol.192
, pp. 615-629
-
-
Morselli, E.1
Mariño, G.2
Bennetzen, M.V.3
Eisenberg, T.4
Megalou, E.5
Schroeder, S.6
Cabrera, S.7
Bénit, P.8
Rustin, P.9
Criollo, A.10
-
120
-
-
41549138483
-
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
-
PMID: 18296641
-
Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, Tsokos M, Alt FW, Finkel T. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci U S A 2008; 105: 3374-9; PMID: 18296641; http://dx. doi. org/10. 1073/pnas. 0712145105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3374-3379
-
-
Lee, I.H.1
Cao, L.2
Mostoslavsky, R.3
Lombard, D.B.4
Liu, J.5
Bruns, N.E.6
Tsokos, M.7
Alt, F.W.8
Finkel, T.9
-
121
-
-
78649338141
-
Autophagy and the integrated stress response
-
PMID: 20965422
-
Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40: 280-93; PMID: 20965422; http://dx. doi. org/10. 1016/j. molcel. 2010. 09. 023.
-
(2010)
Mol Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
122
-
-
77951157657
-
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
-
PMID: 20335657
-
Kume S, Uzu T, Horiike K, Chin-Kanasaki M, Isshiki K, Araki S, Sugimoto T, Haneda M, Kashiwagi A, Koya D. Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney. J Clin Invest 2010; 120: 1043-55; PMID: 20335657; http://dx. doi. org/10. 1172/JCI41376.
-
(2010)
J Clin Invest
, vol.120
, pp. 1043-1055
-
-
Kume, S.1
Uzu, T.2
Horiike, K.3
Chin-Kanasaki, M.4
Isshiki, K.5
Araki, S.6
Sugimoto, T.7
Haneda, M.8
Kashiwagi, A.9
Koya, D.10
-
123
-
-
80052359850
-
Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson disease
-
PMID: 21778691
-
Wu Y, Li X, Zhu JX, Xie W, Le W, Fan Z, Jankovic J, Pan T. Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson disease. Neurosignals 2011; 19: 163-74; PMID: 21778691; http://dx. doi. org/10. 1159/000328516.
-
(2011)
Neurosignals
, vol.19
, pp. 163-174
-
-
Wu, Y.1
Li, X.2
Zhu, J.X.3
Xie, W.4
Le, W.5
Fan, Z.6
Jankovic, J.7
Pan, T.8
-
124
-
-
84868139191
-
Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity
-
PMID: 22575359
-
Jeong JK, Moon MH, Lee YJ, Seol JW, Park SY. Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity. Neurobiol Aging 2013; 34: 146-56; PMID: 22575359; http://dx. doi. org/10. 1016/j. neurobiolaging. 2012. 04. 002.
-
(2013)
Neurobiol Aging
, vol.34
, pp. 146-156
-
-
Jeong, J.K.1
Moon, M.H.2
Lee, Y.J.3
Seol, J.W.4
Park, S.Y.5
-
125
-
-
41949097891
-
C. elegans model identifies genetic modifiers of a-synuclein inclusion formation during aging
-
van Ham TJ, Thijssen KL, Breitling R, Hofstra RM, Plasterk RH, Nollen EA. C. elegans model identifies genetic modifiers of a-synuclein inclusion formation during aging. PLoS Genet 2008; 4: e1000027; http://dx. doi. org/10. 1371/journal. pgen. 1000027.
-
(2008)
PLoS Genet
, vol.4
-
-
van Ham, T.J.1
Thijssen, K.L.2
Breitling, R.3
Hofstra, R.M.4
Plasterk, R.H.5
Nollen, E.A.6
-
126
-
-
84867280590
-
SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy
-
PMID: 22914317
-
Sampaio-Marques B, Felgueiras C, Silva A, Rodrigues M, Tenreiro S, Franssens V, Reichert AS, Outeiro TF, Winderickx J, Ludovico P. SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy. Autophagy 2012; 8: 1494-509; PMID: 22914317; http://dx. doi. org/10. 4161/auto. 21275.
-
(2012)
Autophagy
, vol.8
, pp. 1494-1509
-
-
Sampaio-Marques, B.1
Felgueiras, C.2
Silva, A.3
Rodrigues, M.4
Tenreiro, S.5
Franssens, V.6
Reichert, A.S.7
Outeiro, T.F.8
Winderickx, J.9
Ludovico, P.10
-
127
-
-
84895755121
-
Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan
-
PMID: 24606900
-
Eisenberg T, Schroeder S, Andryushkova A, Pendl T, Küttner V, Bhukel A, Mariño G, Pietrocola F, Harger A, Zimmermann A, et al. Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan. Cell Metab 2014; 19: 431-44; PMID: 24606900; http://dx. doi. org/10. 1016/j. cmet. 2014. 02. 010.
-
(2014)
Cell Metab
, vol.19
, pp. 431-444
-
-
Eisenberg, T.1
Schroeder, S.2
Andryushkova, A.3
Pendl, T.4
Küttner, V.5
Bhukel, A.6
Mariño, G.7
Pietrocola, F.8
Harger, A.9
Zimmermann, A.10
-
128
-
-
84896713080
-
Regulation of autophagy by cytosolic acetyl-coenzyme A
-
PMID: 24560926
-
Marino G, Pietrocola F, Eisenberg T, Kong Y, Malik SA, Andryushkova A, Schroeder S, Pendl T, Harger A, Niso-Santano M, et al. Regulation of autophagy by cytosolic acetyl-coenzyme A. Mol Cell 2014; 53: 710-25; PMID: 24560926; http://dx. doi. org/10. 1016/j. molcel. 2014. 01. 016.
-
(2014)
Mol Cell
, vol.53
, pp. 710-725
-
-
Marino, G.1
Pietrocola, F.2
Eisenberg, T.3
Kong, Y.4
Malik, S.A.5
Andryushkova, A.6
Schroeder, S.7
Pendl, T.8
Harger, A.9
Niso-Santano, M.10
-
129
-
-
70449529855
-
Induction of autophagy by spermidine promotes longevity
-
PMID: 19801973
-
Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, et al. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 2009; 11: 1305-14; PMID: 19801973; http://dx. doi. org/10. 1038/ncb1975.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1305-1314
-
-
Eisenberg, T.1
Knauer, H.2
Schauer, A.3
Büttner, S.4
Ruckenstuhl, C.5
Carmona-Gutierrez, D.6
Ring, J.7
Schroeder, S.8
Magnes, C.9
Antonacci, L.10
-
131
-
-
70350425215
-
Polyamine-rich food decreases age-associated pathology and mortality in aged mice
-
PMID: 19735716
-
Soda K, Dobashi Y, Kano Y, Tsujinaka S, Konishi F. Polyamine-rich food decreases age-associated pathology and mortality in aged mice. Exp Gerontol 2009; 44: 727-32; PMID: 19735716; http://dx. doi. org/10. 1016/j. exger. 2009. 08. 013.
-
(2009)
Exp Gerontol
, vol.44
, pp. 727-732
-
-
Soda, K.1
Dobashi, Y.2
Kano, Y.3
Tsujinaka, S.4
Konishi, F.5
-
132
-
-
0037474250
-
Cellular polyamines promote the aggregation of a-synuclein
-
PMID: 12435752
-
Antony T, Hoyer W, Cherny D, Heim G, Jovin TM, Subramaniam V. Cellular polyamines promote the aggregation of a-synuclein. J Biol Chem 2003; 278: 3235-40; PMID: 12435752; http://dx. doi. org/10. 1074/jbc. M208249200.
-
(2003)
J Biol Chem
, vol.278
, pp. 3235-3240
-
-
Antony, T.1
Hoyer, W.2
Cherny, D.3
Heim, G.4
Jovin, T.M.5
Subramaniam, V.6
-
133
-
-
52349124510
-
Spermine binding to Parkinson protein a-synuclein and its disease-related A30P and A53T mutants
-
PMID: 18693700
-
Grabenauer M, Bernstein SL, Lee JC, Wyttenbach T, Dupuis NF, Gray HB, Winkler JR, Bowers MT. Spermine binding to Parkinson protein a-synuclein and its disease-related A30P and A53T mutants. J Phys Chem B 2008; 112: 11147-54; PMID: 18693700; http://dx. doi. org/10. 1021/jp801175w.
-
(2008)
J Phys Chem B
, vol.112
, pp. 11147-11154
-
-
Grabenauer, M.1
Bernstein, S.L.2
Lee, J.C.3
Wyttenbach, T.4
Dupuis, N.F.5
Gray, H.B.6
Winkler, J.R.7
Bowers, M.T.8
-
134
-
-
78049272757
-
Polyamine pathway contributes to the pathogenesis of Parkinson disease
-
PMID: 20837543
-
Lewandowski NM, Ju S, Verbitsky M, Ross B, Geddie ML, Rockenstein E, Adame A, Muhammad A, Vonsattel JP, Ringe D, et al. Polyamine pathway contributes to the pathogenesis of Parkinson disease. Proc Natl Acad Sci U S A 2010; 107: 16970-5; PMID: 20837543; http://dx. doi. org/10. 1073/pnas. 1011751107.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16970-16975
-
-
Lewandowski, N.M.1
Ju, S.2
Verbitsky, M.3
Ross, B.4
Geddie, M.L.5
Rockenstein, E.6
Adame, A.7
Muhammad, A.8
Vonsattel, J.P.9
Ringe, D.10
-
135
-
-
84886920194
-
Epigenetic regulation of autophagy by the methyltransferase G9a
-
PMID: 23918802
-
Artal-Martinez de Narvajas A, Gomez TS, Zhang JS, Mann AO, Taoda Y, Gorman JA, Herreros-Villanueva M, Gress TM, Ellenrieder V, Bujanda L, et al. Epigenetic regulation of autophagy by the methyltransferase G9a. Mol Cell Biol 2013; 33: 3983-93; PMID: 23918802; http://dx. doi. org/10. 1128/MCB. 00813-13.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 3983-3993
-
-
Artal-Martinez de Narvajas, A.1
Gomez, T.S.2
Zhang, J.S.3
Mann, A.O.4
Taoda, Y.5
Gorman, J.A.6
Herreros-Villanueva, M.7
Gress, T.M.8
Ellenrieder, V.9
Bujanda, L.10
-
136
-
-
78249276176
-
Chromatin remodeling in the aging genome of Drosophila
-
PMID: 20961390
-
Wood JG, Hillenmeyer S, Lawrence C, Chang C, Hosier S, Lightfoot W, Mukherjee E, Jiang N, Schorl C, Brodsky AS, et al. Chromatin remodeling in the aging genome of Drosophila. Aging Cell 2010; 9: 971-8; PMID: 20961390; http://dx. doi. org/10. 1111/j. 1474-9726. 2010. 00624. x.
-
(2010)
Aging Cell
, vol.9
, pp. 971-978
-
-
Wood, J.G.1
Hillenmeyer, S.2
Lawrence, C.3
Chang, C.4
Hosier, S.5
Lightfoot, W.6
Mukherjee, E.7
Jiang, N.8
Schorl, C.9
Brodsky, A.S.10
-
137
-
-
79953131815
-
SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation
-
PMID: 21321083
-
Kapoor-Vazirani P, Kagey JD, Vertino PM. SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation. Mol Cell Biol 2011; 31: 1594-609; PMID: 21321083; http://dx. doi. org/10. 1128/MCB. 00524-10.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1594-1609
-
-
Kapoor-Vazirani, P.1
Kagey, J.D.2
Vertino, P.M.3
-
138
-
-
77954660029
-
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
-
PMID: 20555324
-
Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, Brunet A. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature 2010; 466: 383-7; PMID: 20555324; http://dx. doi. org/10. 1038/nature09195.
-
(2010)
Nature
, vol.466
, pp. 383-387
-
-
Greer, E.L.1
Maures, T.J.2
Hauswirth, A.G.3
Green, E.M.4
Leeman, D.S.5
Maro, G.S.6
Han, S.7
Banko, M.R.8
Gozani, O.9
Brunet, A.10
-
139
-
-
78649718101
-
Essential functions of the histone demethylase lid
-
PMID: 21124823
-
Li L, Greer C, Eisenman RN, Secombe J. Essential functions of the histone demethylase lid. PLoS Genet 2010; 6: e1001221; PMID: 21124823; http://dx. doi. org/10. 1371/journal. pgen. 1001221.
-
(2010)
PLoS Genet
, vol.6
-
-
Li, L.1
Greer, C.2
Eisenman, R.N.3
Secombe, J.4
-
140
-
-
33947152396
-
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
-
PMID: 17311883
-
Secombe J, Li L, Carlos L, Eisenman RN. The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev 2007; 21: 537-51; PMID: 17311883; http://dx. doi. org/10. 1101/gad. 1523007.
-
(2007)
Genes Dev
, vol.21
, pp. 537-551
-
-
Secombe, J.1
Li, L.2
Carlos, L.3
Eisenman, R.N.4
-
141
-
-
84855321183
-
Histone methylation makes its mark on longevity
-
PMID: 22177962
-
Han S, Brunet A. Histone methylation makes its mark on longevity. Trends Cell Biol 2012; 22: 42-9; PMID: 22177962; http://dx. doi. org/10. 1016/j. tcb. 2011. 11. 001.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 42-49
-
-
Han, S.1
Brunet, A.2
-
142
-
-
84858142662
-
MicroRNAs and their roles in aging
-
PMID: 22294612
-
Smith-Vikos T, Slack FJ. MicroRNAs and their roles in aging. J Cell Sci 2012; 125: 7-17; PMID: 22294612; http://dx. doi. org/10. 1242/jcs. 099200.
-
(2012)
J Cell Sci
, vol.125
, pp. 7-17
-
-
Smith-Vikos, T.1
Slack, F.J.2
-
143
-
-
80053210307
-
Ageassociated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans
-
PMID: 21810936
-
Kato M, Chen X, Inukai S, Zhao H, Slack FJ. Ageassociated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans. RNA 2011; 17: 1804-20; PMID: 21810936; http://dx. doi. org/10. 1261/rna. 2714411.
-
(2011)
RNA
, vol.17
, pp. 1804-1820
-
-
Kato, M.1
Chen, X.2
Inukai, S.3
Zhao, H.4
Slack, F.J.5
-
144
-
-
78650490230
-
MicroRNAs both promote and antagonize longevity in C. elegans
-
PMID: 21129974
-
de Lencastre A, Pincus Z, Zhou K, Kato M, Lee SS, Slack FJ. MicroRNAs both promote and antagonize longevity in C. elegans. Curr Biol 2010; 20: 2159-68; PMID: 21129974; http://dx. doi. org/10. 1016/j. cub. 2010. 11. 015.
-
(2010)
Curr Biol
, vol.20
, pp. 2159-2168
-
-
de Lencastre, A.1
Pincus, Z.2
Zhou, K.3
Kato, M.4
Lee, S.S.5
Slack, F.J.6
-
145
-
-
33744485559
-
Modulated microRNA expression during adult lifespan in Caenorhabditis elegans
-
PMID: 16842496
-
Ibanez-Ventoso C, Yang M, Guo S, Robins H, Padgett RW, Driscoll M. Modulated microRNA expression during adult lifespan in Caenorhabditis elegans. Aging Cell 2006; 5: 235-46; PMID: 16842496; http://dx. doi. org/10. 1111/j. 1474-9726. 2006. 00210. x.
-
(2006)
Aging Cell
, vol.5
, pp. 235-246
-
-
Ibanez-Ventoso, C.1
Yang, M.2
Guo, S.3
Robins, H.4
Padgett, R.W.5
Driscoll, M.6
-
146
-
-
84872616169
-
MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9
-
PMID: 22081425
-
Yang J, Chen D, He Y, Meléndez A, Feng Z, Hong Q, Bai X, Li Q, Cai G, Wang J, et al. MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9. Age (Dordr) 2011; 35: 11-22; PMID: 22081425; http://dx. doi. org/10. 1007/s11357-011-9324-3.
-
(2011)
Age (Dordr)
, vol.35
, pp. 11-22
-
-
Yang, J.1
Chen, D.2
He, Y.3
Meléndez, A.4
Feng, Z.5
Hong, Q.6
Bai, X.7
Li, Q.8
Cai, G.9
Wang, J.10
-
147
-
-
80051604377
-
Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice
-
PMID: 21415464
-
Khanna A, Muthusamy S, Liang R, Sarojini H, Wang E. Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice. Aging (Albany NY) 2011; 3: 223-36; PMID: 21415464.
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 223-236
-
-
Khanna, A.1
Muthusamy, S.2
Liang, R.3
Sarojini, H.4
Wang, E.5
-
148
-
-
84862776753
-
The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila
-
PMID: 22343898
-
Liu N, Landreh M, Cao K, Abe M, Hendriks GJ, Kennerdell JR, Zhu Y, Wang LS, Bonini NM. The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila. Nature 2012; 482: 519-23; PMID: 22343898; http://dx. doi. org/10. 1038/nature10810.
-
(2012)
Nature
, vol.482
, pp. 519-523
-
-
Liu, N.1
Landreh, M.2
Cao, K.3
Abe, M.4
Hendriks, G.J.5
Kennerdell, J.R.6
Zhu, Y.7
Wang, L.S.8
Bonini, N.M.9
-
149
-
-
84894060596
-
- 2 and sensitizes human hepatocellular carcinoma cells to sorafenib treatment
-
PMID: 23862748
-
- 2 and sensitizes human hepatocellular carcinoma cells to sorafenib treatment. Technol Cancer Res Treat 2014; 13: 77-86; PMID: 23862748.
-
(2014)
Technol Cancer Res Treat
, vol.13
, pp. 77-86
-
-
Yang, F.1
Li, Q.J.2
Gong, Z.B.3
Zhou, L.4
You, N.5
Wang, S.6
Li, X.L.7
Li, J.J.8
An, J.Z.9
Wang, D.S.10
-
150
-
-
51649115553
-
miR-34a repression of SIRT1 regulates apoptosis
-
PMID: 18755897
-
Yamakuchi M, Ferlito M, Lowenstein CJ. miR-34a repression of SIRT1 regulates apoptosis. Proc Natl Acad Sci U S A 2008; 105: 13421-6; PMID: 18755897; http://dx. doi. org/10. 1073/pnas. 0801613105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13421-13426
-
-
Yamakuchi, M.1
Ferlito, M.2
Lowenstein, C.J.3
-
151
-
-
85046981182
-
miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1
-
PMID: 22248718
-
Korkmaz G, le Sage C, Tekirdag KA, Agami R, Gozuacik D. miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. Autophagy 2012; 8: 165-76; PMID: 22248718; http://dx. doi. org/10. 4161/auto. 8. 2. 18351.
-
(2012)
Autophagy
, vol.8
, pp. 165-176
-
-
Korkmaz, G.1
le Sage, C.2
Tekirdag, K.A.3
Agami, R.4
Gozuacik, D.5
-
152
-
-
84892752232
-
MIR376A is a regulator of starvation-induced autophagy
-
PMID: 24358205
-
Korkmaz G, Tekirdag KA, Ozturk DG, Kosar A, Sezerman OU, Gozuacik D. MIR376A is a regulator of starvation-induced autophagy. PLoS One 2013; 8: e82556; PMID: 24358205; http://dx. doi. org/10. 1371/journal. pone. 0082556.
-
(2013)
PLoS One
, vol.8
-
-
Korkmaz, G.1
Tekirdag, K.A.2
Ozturk, D.G.3
Kosar, A.4
Sezerman, O.U.5
Gozuacik, D.6
-
153
-
-
84877344944
-
MIR181A regulates starvation-and rapamycin-induced autophagy through targeting of ATG5
-
PMID: 23322078
-
Tekirdag KA, Korkmaz G, Ozturk DG, Agami R, Gozuacik D. MIR181A regulates starvation-and rapamycin-induced autophagy through targeting of ATG5. Autophagy 2013; 9: 374-85; PMID: 23322078; http://dx. doi. org/10. 4161/auto. 23117.
-
(2013)
Autophagy
, vol.9
, pp. 374-385
-
-
Tekirdag, K.A.1
Korkmaz, G.2
Ozturk, D.G.3
Agami, R.4
Gozuacik, D.5
-
154
-
-
84893808368
-
Regulation of autophagy by miR-30d impacts sensitivity of anaplastic thyroid carcinoma to cisplatin
-
PMID: 24345332
-
Zhang Y, Yang WQ, Zhu H, Qian YY, Zhou L, Ren YJ, Ren XC, Zhang L, Liu XP, Liu CG, et al. Regulation of autophagy by miR-30d impacts sensitivity of anaplastic thyroid carcinoma to cisplatin. Biochem Pharmacol 2014; 87: 562-70; PMID: 24345332; http://dx. doi. org/10. 1016/j. bcp. 2013. 12. 004.
-
(2014)
Biochem Pharmacol
, vol.87
, pp. 562-570
-
-
Zhang, Y.1
Yang, W.Q.2
Zhu, H.3
Qian, Y.Y.4
Zhou, L.5
Ren, Y.J.6
Ren, X.C.7
Zhang, L.8
Liu, X.P.9
Liu, C.G.10
-
155
-
-
84873718626
-
mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells
-
PMID: 23274497
-
Yang X, Zhong X, Tanyi JL, Shen J, Xu C, Gao P, Zheng TM, DeMichele A, Zhang L. mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells. Biochem Biophys Res Commun 2013; 431: 617-22; PMID: 23274497; http://dx. doi. org/10. 1016/j. bbrc. 2012. 12. 083.
-
(2013)
Biochem Biophys Res Commun
, vol.431
, pp. 617-622
-
-
Yang, X.1
Zhong, X.2
Tanyi, J.L.3
Shen, J.4
Xu, C.5
Gao, P.6
Zheng, T.M.7
DeMichele, A.8
Zhang, L.9
-
156
-
-
81255143302
-
microRNA-101 is a potent inhibitor of autophagy
-
PMID: 21915098
-
Frankel LB, Wen J, Lees M, Høyer-Hansen M, Farkas T, Krogh A, Jäättelä M, Lund AH. microRNA-101 is a potent inhibitor of autophagy. EMBO J 2011; 30: 4628-41; PMID: 21915098; http://dx. doi. org/10. 1038/emboj. 2011. 331.
-
(2011)
EMBO J
, vol.30
, pp. 4628-4641
-
-
Frankel, L.B.1
Wen, J.2
Lees, M.3
Høyer-Hansen, M.4
Farkas, T.5
Krogh, A.6
Jäättelä, M.7
Lund, A.H.8
-
157
-
-
84876211114
-
miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells
-
PMID: 23483142
-
Xu Y, An Y, Wang Y, Zhang C, Zhang H, Huang C, Jiang H, Wang X, Li X. miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells. Oncol Rep 2013; 29: 2019-24; PMID: 23483142.
-
(2013)
Oncol Rep
, vol.29
, pp. 2019-2024
-
-
Xu, Y.1
An, Y.2
Wang, Y.3
Zhang, C.4
Zhang, H.5
Huang, C.6
Jiang, H.7
Wang, X.8
Li, X.9
-
158
-
-
84894436700
-
Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway
-
PMID: 24262949
-
Wan G, Xie W, Liu Z, Xu W, Lao Y, Huang N, Cui K, Liao M, He J, Jiang Y, et al. Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway. Autophagy 2013; 10: 70-9; PMID: 24262949; http://dx. doi. org/10. 4161/auto. 26534.
-
(2013)
Autophagy
, vol.10
, pp. 70-79
-
-
Wan, G.1
Xie, W.2
Liu, Z.3
Xu, W.4
Lao, Y.5
Huang, N.6
Cui, K.7
Liao, M.8
He, J.9
Jiang, Y.10
-
159
-
-
85011941404
-
Alteration in Autophagic-lysosomal Potential During Aging and Neurological Diseases: The microRNA Perspective
-
Tekirdag KA, Ozturk DG, Gozuacik D. Alteration in Autophagic-lysosomal Potential During Aging and Neurological Diseases: The microRNA Perspective. Curr Pathobiol Rep 2013; 1: 247-261; http://dx. doi. org/10. 1007/s40139-013-0031-x.
-
(2013)
Curr Pathobiol Rep
, vol.1
, pp. 247-261
-
-
Tekirdag, K.A.1
Ozturk, D.G.2
Gozuacik, D.3
-
160
-
-
84875198920
-
Transcriptional regulation and its misregulation in disease
-
PMID: 23498934
-
Lee TI, Young RA. Transcriptional regulation and its misregulation in disease. Cell 2013; 152: 1237-51; PMID: 23498934; http://dx. doi. org/10. 1016/j. cell. 2013. 02. 014.
-
(2013)
Cell
, vol.152
, pp. 1237-1251
-
-
Lee, T.I.1
Young, R.A.2
-
161
-
-
84902652820
-
Transcriptional regulation by Pho23 modulates the frequency of autophagosome formation
-
PMID: 24881874
-
Jin M, He D, Backues SK, Freeberg MA, Liu X, Kim JK, Klionsky DJ. Transcriptional regulation by Pho23 modulates the frequency of autophagosome formation. Curr Biol 2014; 24: 1314-22; PMID: 24881874; http://dx. doi. org/10. 1016/j. cub. 2014. 04. 048.
-
(2014)
Curr Biol
, vol.24
, pp. 1314-1322
-
-
Jin, M.1
He, D.2
Backues, S.K.3
Freeberg, M.A.4
Liu, X.5
Kim, J.K.6
Klionsky, D.J.7
-
162
-
-
84877577382
-
Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvationinduced autophagy and causes a severe, late-onset myopathy
-
PMID: 23602450
-
Castets P, Lin S, Rion N, Di Fulvio S, Romanino K, Guridi M, Frank S, Tintignac LA, Sinnreich M, Rüegg MA. Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvationinduced autophagy and causes a severe, late-onset myopathy. Cell Metab 2013; 17: 731-44; PMID: 23602450; http://dx. doi. org/10. 1016/j. cmet. 2013. 03. 015.
-
(2013)
Cell Metab
, vol.17
, pp. 731-744
-
-
Castets, P.1
Lin, S.2
Rion, N.3
Di Fulvio, S.4
Romanino, K.5
Guridi, M.6
Frank, S.7
Tintignac, L.A.8
Sinnreich, M.9
Rüegg, M.A.10
-
163
-
-
84863806968
-
Global heterochromatin loss: A unifying theory of aging?
-
PMID: 22647267
-
Tsurumi A, Li WX. Global heterochromatin loss: a unifying theory of aging? Epigenetics 2012; 7: 680-8; PMID: 22647267; http://dx. doi. org/10. 4161/epi. 20540.
-
(2012)
Epigenetics
, vol.7
, pp. 680-688
-
-
Tsurumi, A.1
Li, W.X.2
-
164
-
-
84913530417
-
Histone methylation and aging: Lessons learned from model systems
-
PMID: 24859460
-
McCauley BS, Dang W. Histone methylation and aging: Lessons learned from model systems. Biochim Biophys Acta 2014; PMID: 24859460; 1839 (12): 1454-62.
-
(2014)
Biochim Biophys Acta
, vol.1839
, Issue.12
, pp. 1454-1462
-
-
McCauley, B.S.1
Dang, W.2
-
165
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
PMID: 22258505
-
He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 2012; 481: 511-5; PMID: 22258505; http://dx. doi. org/10. 1038/nature10758.
-
(2012)
Nature
, vol.481
, pp. 511-515
-
-
He, C.1
Bassik, M.C.2
Moresi, V.3
Sun, K.4
Wei, Y.5
Zou, Z.6
An, Z.7
Loh, J.8
Fisher, J.9
Sun, Q.10
-
166
-
-
33947401070
-
Autophagy regulates ageing in C. elegans
-
PMID: 17204841
-
Hars ES, Qi H, Ryazanov AG, Jin S, Cai L, Hu C, Liu LF. Autophagy regulates ageing in C. elegans. Autophagy 2007; 3: 93-5; PMID: 17204841; http://dx. doi. org/10. 4161/auto. 3636.
-
(2007)
Autophagy
, vol.3
, pp. 93-95
-
-
Hars, E.S.1
Qi, H.2
Ryazanov, A.G.3
Jin, S.4
Cai, L.5
Hu, C.6
Liu, L.F.7
-
167
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
PMID: 12958363
-
Melendez A, Tallóczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 2003; 301: 1387-91; PMID: 12958363; http://dx. doi. org/10. 1126/science. 1087782.
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Melendez, A.1
Tallóczy, Z.2
Seaman, M.3
Eskelinen, E.L.4
Hall, D.H.5
Levine, B.6
-
168
-
-
67650594823
-
A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors
-
PMID: 19632181
-
Grove CA, De Masi F, Barrasa MI, Newburger DE, Alkema MJ, Bulyk ML, Walhout AJ. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 2009; 138: 314-27; PMID: 19632181; http://dx. doi. org/10. 1016/j. cell. 2009. 04. 058.
-
(2009)
Cell
, vol.138
, pp. 314-327
-
-
Grove, C.A.1
De Masi, F.2
Barrasa, M.I.3
Newburger, D.E.4
Alkema, M.J.5
Bulyk, M.L.6
Walhout, A.J.7
-
169
-
-
84923820926
-
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
-
PMID: 25720963
-
Medina DL, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, Montefusco S, Scotto-Rosato A, Prezioso C, Forrester A, Settembre C, Wang W, Gao Q, Xu H, Sandri M, Rizzuto R, De Matteis MA, Ballabio A. Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB. Nat Cell Biol 2015; 17(3): 288-99; PMID: 25720963.
-
(2015)
Nat Cell Biol
, vol.17
, Issue.3
, pp. 288-299
-
-
Medina, D.L.1
Di Paola, S.2
Peluso, I.3
Armani, A.4
De Stefani, D.5
Venditti, R.6
Montefusco, S.7
Scotto-Rosato, A.8
Prezioso, C.9
Forrester, A.10
Settembre, C.11
Wang, W.12
Gao, Q.13
Xu, H.14
Sandri, M.15
Rizzuto, R.16
De Matteis, M.A.17
Ballabio, A.18
-
170
-
-
67650243271
-
Autophagy genes mediate the effect of calcineurin on life span in C. elegans
-
PMID: 19279398
-
Dwivedi M, Song HO, Ahnn J. Autophagy genes mediate the effect of calcineurin on life span in C. elegans. Autophagy 2009; 5(5): 604-7; PMID: 19279398.
-
(2009)
Autophagy
, vol.5
, Issue.5
, pp. 604-607
-
-
Dwivedi, M.1
Song, H.O.2
Ahnn, J.3
-
171
-
-
84927636147
-
Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy
-
Milan G, Romanello V, Pescatore F, Armani A, Paik J-H, Frasson L, Seydel A, Zhao J, Abraham R, Goldberg AL, et al. Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy. Nature Communications 2015; 6; http://dx. doi. org/10. 1038/ncomms7670.
-
(2015)
Nature Communications
, pp. 6
-
-
Milan, G.1
Romanello, V.2
Pescatore, F.3
Armani, A.4
Paik, J.-H.5
Frasson, L.6
Seydel, A.7
Zhao, J.8
Abraham, R.9
Goldberg, A.L.10
|