The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris

Science Signaling

Volumn 7, Issue 309, 2014, Pages

  Martina, José A ^a   Diab, Heba I ^a   Lishu, Li ^b   Jeong A, Lim ^b   Patange, Simona ^a   Raben, Nina ^b   Puertollano, Rosa ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E3; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; ESTRONE; GUANOSINE TRIPHOSPHATASE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MITF PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE; TFE3 PROTEIN, HUMAN;

ARTICLE; AUTOPHAGY; BIOGENESIS; CELL INTERACTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; ENERGY METABOLISM; EXOCYTOSIS; GENE CONTROL; GENE OVEREXPRESSION; GLYCOGEN STORAGE DISEASE TYPE 2; HOMEOSTASIS; HUMAN; HUMAN CELL; LYSOSOME; LYSOSOME STORAGE DISEASE; NUTRIENT AVAILABILITY; PHOSPHORYLATION; PRIORITY JOURNAL; PROMOTER REGION; STARVATION; CELL FRACTIONATION; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; TRANSFORMED CELL LINE;

AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE, TRANSFORMED; ESTRONE; GTP PHOSPHOHYDROLASES; HUMANS; LYSOSOMES; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SUBCELLULAR FRACTIONS; TOR SERINE-THREONINE KINASES;

EID: 84893055506     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004754     Document Type: Article

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