Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification

PLoS Genetics

Volumn 10, Issue 5, 2014, Pages

  Ruckenstuhl, Christoph ^a   Netzberger, Christine ^a   Entfellner, Iryna ^a   Carmona Gutierrez, Didac ^a   Kickenweiz, Thomas ^a   Stekovic, Slaven ^a   Gleixner, Christina ^a   Schmid, Christian ^a   Klug, Lisa ^a   Sorgo, Alice G ^a   Eisenberg, Tobias ^a   Büttner, Sabrina ^a   Mariño, Guillermo ^b,c,d   Koziel, Rafal ^e   Jansen Dürr, Pidder ^e   Fröhlich, Kai Uwe ^a   Kroemer, Guido ^b,c,f,g,h   Madeo, Frank ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b Institut Gustave Roussy   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^f CENTRE DE RECHERCHE DES CORDELIERS   (France)

^g HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^h UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALKALINE PHOSPHATASE; AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; AUTOPHAGY PROTEIN 8; METHIONINE; UNCLASSIFIED DRUG; ACID;

ACIDIFICATION; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL AGING; CELL SURVIVAL; CELL VACUOLE; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGAL STRAIN; FUNGUS GROWTH; GENE DELETION; LIFE EXTENSION; LONGEVITY; NECROSIS; NONHUMAN; PHENOTYPE; SACCHAROMYCES CEREVISIAE; FUNGAL GENE; IMMUNOLOGY; METABOLISM; PH; PHYSIOLOGY;

ACIDS; AUTOPHAGY; GENE DELETION; GENES, FUNGAL; HYDROGEN-ION CONCENTRATION; LONGEVITY; METHIONINE; SACCHAROMYCES CEREVISIAE; VACUOLES;

EID: 84901615928     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004347     Document Type: Article

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