메뉴 건너뛰기




Volumn 516, Issue 729, 2014, Pages 112-115

Nutrient-sensing nuclear receptors coordinate autophagy

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 [2 [3 CYCLOHEXYL 1 (4 CYCLOHEXYLBUTYL)UREIDO]ETHYL]PHENYLTHIO] 2 METHYLPROPIONIC ACID; 3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; FARNESOID X RECEPTOR; FAT DROPLET; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN;

EID: 84923031534     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13961     Document Type: Article
Times cited : (417)

References (47)
  • 1
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima, N., Levine, B., Cuervo, A. M. & Klionsky, D. J. Autophagy fights disease through cellular self-digestion. Nature 451, 1069-1075 (2008).
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 2
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine, B. & Kroemer, G. Autophagy in the pathogenesis of disease. Cell 132, 27-42 (2008).
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 3
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy andmetabolism
    • Rabinowitz, J. D.& White, E. Autophagy andmetabolism. Science 330, 1344-1348 (2010).
    • (2010) Science , vol.330 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 4
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • Evans, R. M., Barish, G. D. & Wang, Y. X. PPARs and the complex journey to obesity. Nature Med. 10, 355-361 (2004).
    • (2004) Nature Med. , vol.10 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.X.3
  • 5
    • 0034730319 scopus 로고    scopus 로고
    • Don't knowmuchbile-ology
    • Chawla, A.,Saez, E.& Evans, R.M.Don't knowmuchbile-ology.Cell103, 1-4(2000).
    • (2000) Cell , vol.103 , pp. 1-4
    • Chawla, A.1    Saez, E.2    Evans, R.M.3
  • 6
    • 0032797852 scopus 로고    scopus 로고
    • Regulation of glucose production by the liver
    • Nordlie, R. C., Foster, J. D. & Lange, A. J. Regulation of glucose production by the liver. Annu. Rev. Nutr. 19, 379-406 (1999).
    • (1999) Annu. Rev. Nutr. , vol.19 , pp. 379-406
    • Nordlie, R.C.1    Foster, J.D.2    Lange, A.J.3
  • 7
    • 84859778293 scopus 로고    scopus 로고
    • MTOR signaling in growth control and disease
    • Laplante, M. & Sabatini, D. M. mTOR signaling in growth control and disease. Cell 149, 274-293 (2012).
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 8
    • 84862908818 scopus 로고    scopus 로고
    • AMPK and mTOR in cellular energy homeostasis and drug targets
    • Inoki, K., Kim, J. & Guan, K. L.AMPK andmTOR in cellular energy homeostasis and drug targets. Annu. Rev. Pharmacol. Toxicol. 52, 381-400 (2012).
    • (2012) Annu. Rev. Pharmacol. Toxicol. , vol.52 , pp. 381-400
    • Inoki, K.1    Kim, J.2    Guan, K.L.3
  • 9
    • 84858782079 scopus 로고    scopus 로고
    • AMPK: A nutrient and energy sensor that maintains energy homeostasis
    • Hardie, D. G., Ross, F. A. & Hawley, S. A. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nature Rev. Mol. Cell Biol. 13, 251-262 (2012).
    • (2012) Nature Rev. Mol. Cell Biol. , vol.13 , pp. 251-262
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 10
    • 84923285482 scopus 로고    scopus 로고
    • Lysosome: Regulator of lipid degradation pathways
    • 21 July
    • Settembre, C. & Ballabio, A. Lysosome: regulator of lipid degradation pathways. Trends Cell Biol. http://dx.doi.org/10.1016/j.tcb.2014.06.006 (21 July 2014).
    • (2014) Trends Cell Biol.
    • Settembre, C.1    Ballabio, A.2
  • 11
    • 0026551309 scopus 로고
    • Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
    • Göttlicher, M., Widmark, E., Li, Q. Gustafsson, J. A. Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc. Natl Acad. Sci. USA 89, 4653-4657 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 4653-4657
    • Göttlicher, M.1    Widmark, E.2    Li, Q.3    Gustafsson, J.A.4
  • 12
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
    • Keller, H. et al. Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc. Natl Acad. Sci. USA 90, 2160-2164 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 2160-2164
    • Keller, H.1
  • 13
    • 33645509321 scopus 로고    scopus 로고
    • Farnesoid X receptor is essential for normal glucose homeostasis
    • Ma, K., Saha, P. K., Chan, L. & Moore, D. D. Farnesoid X receptor is essential for normal glucose homeostasis. J. Clin. Invest. 116, 1102-1109 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 1102-1109
    • Ma, K.1    Saha, P.K.2    Chan, L.3    Moore, D.D.4
  • 14
    • 34548077575 scopus 로고    scopus 로고
    • Dissection of the autophagosome maturation process by a novel reporter protein, tandemfluorescent-tagged LC3
    • Kimura, S., Noda, T. & Yoshimori, T. Dissection of the autophagosome maturation process by a novel reporter protein, tandemfluorescent-tagged LC3. Autophagy 3, 452-460 (2007).
    • (2007) Autophagy , vol.3 , pp. 452-460
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 15
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima, N., Yoshimori, T. & Levine, B. Methods in mammalian autophagy research. Cell 140, 313-326 (2010).
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 16
    • 84862295360 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy
    • Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8, 445-544 (2012).
    • (2012) Autophagy , vol.8 , pp. 445-544
    • Klionsky, D.J.1
  • 17
    • 0034632762 scopus 로고    scopus 로고
    • Identification of a chemical tool for the orphannuclear receptor FXR
    • Maloney, P. R. et al. Identification of a chemical tool for the orphannuclear receptor FXR. J. Med. Chem. 43, 2971-2974 (2000).
    • (2000) J. Med. Chem. , vol.43 , pp. 2971-2974
    • Maloney, P.R.1
  • 18
    • 0035821394 scopus 로고    scopus 로고
    • Identification of a subtype selective human PPARa agonist through parallel-array synthesis
    • Brown, P. J. et al. Identification of a subtype selective human PPARa agonist through parallel-array synthesis. Bioorg. Med. Chem. Lett. 11, 1225-1227 (2001).
    • (2001) Bioorg. Med. Chem. Lett. , vol.11 , pp. 1225-1227
    • Brown, P.J.1
  • 19
    • 79551598347 scopus 로고    scopus 로고
    • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
    • Kim, J., Kundu, M., Viollet, B. & Guan, K. L. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nature Cell Biol. 13, 132-141 (2011).
    • (2011) Nature Cell Biol. , vol.13 , pp. 132-141
    • Kim, J.1    Kundu, M.2    Viollet, B.3    Guan, K.L.4
  • 20
    • 65549145048 scopus 로고    scopus 로고
    • An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions ofmTORC1
    • Thoreen, C. C. et al. An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions ofmTORC1. J. Biol. Chem. 284, 8023-8032 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 8023-8032
    • Thoreen, C.C.1
  • 21
    • 0028997684 scopus 로고
    • Targeted disruption of the a isoformof the peroxisome proliferatoractivated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee, S. S. et al. Targeted disruption of the a isoformof the peroxisome proliferatoractivated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15, 3012-3022 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3012-3022
    • Lee, S.S.1
  • 22
    • 0034664729 scopus 로고    scopus 로고
    • Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
    • Sinal, C. J. et al. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102, 731-744 (2000).
    • (2000) Cell , vol.102 , pp. 731-744
    • Sinal, C.J.1
  • 23
    • 1542283812 scopus 로고    scopus 로고
    • Vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima, N., Yamamoto, A., Matsui, M., Yoshimori, T. & Ohsumi, Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol. Biol. Cell 15, 1101-1111 (2004).
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 24
    • 21044455137 scopus 로고    scopus 로고
    • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
    • Komatsu, M. et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J. Cell Biol. 169, 425-434 (2005).
    • (2005) J. Cell Biol. , vol.169 , pp. 425-434
    • Komatsu, M.1
  • 25
    • 77950605769 scopus 로고    scopus 로고
    • Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine
    • Thomas, A. M. et al. Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine. Hepatology 51, 1410-1419 (2010).
    • (2010) Hepatology , vol.51 , pp. 1410-1419
    • Thomas, A.M.1
  • 26
    • 0042666932 scopus 로고    scopus 로고
    • Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression
    • Claudel, T. et al. Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression. Gastroenterology 125, 544-555 (2003).
    • (2003) Gastroenterology , vol.125 , pp. 544-555
    • Claudel, T.1
  • 27
    • 80052380574 scopus 로고    scopus 로고
    • Farnesoid X receptor represses hepatic human APOA gene expression
    • Chennamsetty, I. et al. Farnesoid X receptor represses hepatic human APOA gene expression. J. Clin. Invest. 121, 3724-3734 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 3724-3734
    • Chennamsetty, I.1
  • 28
    • 84922968506 scopus 로고    scopus 로고
    • Transcriptional regulation of autophagy by an FXR-CREBaxis
    • this issue
    • Seok, S. et al. Transcriptional regulation of autophagy by an FXR-CREBaxis. Nature http://dx.doi.org/10.1038/nature13949 (this issue).
    • Nature
    • Seok, S.1
  • 29
    • 0036086509 scopus 로고    scopus 로고
    • Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis
    • Kerr, T. A. et al. Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis. Dev. Cell 2, 713-720 (2002).
    • (2002) Dev. Cell , vol.2 , pp. 713-720
    • Kerr, T.A.1
  • 30
    • 18444377348 scopus 로고    scopus 로고
    • Redundant pathways for negative feedback regulation of bile acid production
    • Wang, L. et al. Redundant pathways for negative feedback regulation of bile acid production. Dev. Cell 2, 721-731 (2002).
    • (2002) Dev. Cell , vol.2 , pp. 721-731
    • Wang, L.1
  • 31
    • 67849122320 scopus 로고    scopus 로고
    • MEME SUITE: Tools for motif discovery and searching
    • Bailey, T. L. et al. MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res. 37, W202-W208 (2009).
    • (2009) Nucleic Acids Res. , vol.37 , pp. W202-W208
    • Bailey, T.L.1
  • 33
    • 84891073800 scopus 로고    scopus 로고
    • Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor
    • Sun, Z. et al. Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor. Mol. Cell 52, 769-782 (2013).
    • (2013) Mol. Cell , vol.52 , pp. 769-782
    • Sun, Z.1
  • 34
    • 79952529158 scopus 로고    scopus 로고
    • A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
    • Feng, D. et al. A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science 331, 1315-1319 (2011).
    • (2011) Science , vol.331 , pp. 1315-1319
    • Feng, D.1
  • 35
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast andmemory-efficient alignment of short DNA sequences to the human genome
    • Langmead, B., Trapnell, C., Pop, M. Salzberg, S. L. Ultrafast andmemory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 10, R25 (2009).
    • (2009) Genome Biol. , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 36
    • 53849146020 scopus 로고    scopus 로고
    • Model-based analysis of ChIP-Seq (MACS)
    • Zhang, Y. et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 9, R137 (2008).
    • (2008) Genome Biol. , vol.9 , pp. R137
    • Zhang, Y.1
  • 37
    • 0036079158 scopus 로고    scopus 로고
    • The human genomebrowser at UCSC
    • Kent, W. J. et al. The human genomebrowser atUCSC.GenomeRes. 12, 996-1006 (2002).
    • (2002) Genome Res. , vol.12 , pp. 996-1006
    • Kent, W.J.1
  • 38
    • 41749114288 scopus 로고    scopus 로고
    • Autophagy: Basic principles and relevance to disease
    • Kundu, M. & Thompson, C. B. Autophagy: basic principles and relevance to disease. Annu. Rev. Pathol. 3, 427-455 (2008).
    • (2008) Annu. Rev. Pathol. , vol.3 , pp. 427-455
    • Kundu, M.1    Thompson, C.B.2
  • 39
    • 84875083992 scopus 로고    scopus 로고
    • SnapShot: Selective autophagy
    • Jin, M., Liu, X. & Klionsky, D. J. SnapShot: Selective autophagy. Cell 152, 368-368 (2013).
    • (2013) Cell , vol.152 , pp. 368-368
    • Jin, M.1    Liu, X.2    Klionsky, D.J.3
  • 40
    • 80955177196 scopus 로고    scopus 로고
    • TFEB links autophagy to lysosomal biogenesis
    • Settembre, C. et al. TFEB links autophagy to lysosomal biogenesis. Science 332, 1429-1433 (2011).
    • (2011) Science , vol.332 , pp. 1429-1433
    • Settembre, C.1
  • 41
    • 84874192375 scopus 로고    scopus 로고
    • FOXO3A directs a protective autophagy program in haematopoietic stem cells
    • Warr, M. R. et al. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature 494, 323-327 (2013).
    • (2013) Nature , vol.494 , pp. 323-327
    • Warr, M.R.1
  • 42
    • 84873709314 scopus 로고    scopus 로고
    • Identification of a candidate therapeutic autophagyinducing peptide
    • Shoji-Kawata, S. et al. Identification of a candidate therapeutic autophagyinducing peptide. Nature 494, 201-206 (2013).
    • (2013) Nature , vol.494 , pp. 201-206
    • Shoji-Kawata, S.1
  • 43
    • 84870880174 scopus 로고    scopus 로고
    • The hairpin-type tail-anchoredSNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes
    • Itakura, E., Kishi-Itakura, C. Mizushima, N. The hairpin-type tail-anchoredSNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151, 1256-1269 (2012).
    • (2012) Cell , vol.151 , pp. 1256-1269
    • Itakura, E.1    Kishi-Itakura, C.2    Mizushima, N.3
  • 44
    • 84859901966 scopus 로고    scopus 로고
    • Genome-wide siRNA screen reveals amino acid starvationinduced autophagy requires SCOC and WAC
    • McKnight, N. C. et al. Genome-wide siRNA screen reveals amino acid starvationinduced autophagy requires SCOC and WAC. EMBO J. 31, 1931-1946 (2012).
    • (2012) EMBO J. , vol.31 , pp. 1931-1946
    • McKnight, N.C.1
  • 45
    • 0014444144 scopus 로고
    • A low-viscosity epoxy resin embedding medium for electron microscopy
    • Spurr, A. R. A low-viscosity epoxy resin embedding medium for electron microscopy. J. Ultrastruct. Res. 26, 31-42 (1969).
    • (1969) J. Ultrastruct. Res. , vol.26 , pp. 31-42
    • Spurr, A.R.1
  • 47
    • 52649114611 scopus 로고
    • The use of lead citrate at high pH as an electron-opaque stain in electron microscopy
    • Reynolds, E. S. The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J. Cell Biol. 17, 208-212 (1963).
    • (1963) J. Cell Biol. , vol.17 , pp. 208-212
    • Reynolds, E.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.