메뉴 건너뛰기




Volumn 15, Issue 6, 2013, Pages 668-676

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

Author keywords

[No Author keywords available]

Indexed keywords

ACID LIPASE; LYSOSOMAL LIPASE LIPL 1; LYSOSOMAL LIPASE LIPL 2; LYSOSOMAL LIPASE LIPL 3; LYSOSOMAL LIPASE LIPL 4; LYSOSOMAL LIPASE LIPL 5; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HLH 30; TRANSCRIPTION FACTOR MXL 3; UNCLASSIFIED DRUG;

EID: 84878533962     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2741     Document Type: Article
Times cited : (241)

References (33)
  • 1
    • 84858036387 scopus 로고
    • A note on the absorption of fat
    • Whitehead, R. H. A note on the absorption of fat. Am. J. Physiol. 24, 294-296 (1909).
    • (1909) Am. J. Physiol. , vol.24 , pp. 294-296
    • Whitehead, R.H.1
  • 2
    • 65949095803 scopus 로고    scopus 로고
    • Autophagy regulates lipid metabolism
    • Singh, R. et al. Autophagy regulates lipid metabolism. Nature 458, 1131-1135 (2009).
    • (2009) Nature , vol.458 , pp. 1131-1135
    • Singh, R.1
  • 3
    • 69449107552 scopus 로고    scopus 로고
    • Lipases in lysosomes, what for?
    • Czaja, M. J. Cuervo, A. M. Lipases in lysosomes, what for? Autophagy 5, 866-867 (2009).
    • (2009) Autophagy , vol.5 , pp. 866-867
    • Czaja, M.J.1    Cuervo, A.M.2
  • 5
    • 0038406208 scopus 로고    scopus 로고
    • Global analysis of dauer gene expression in Caenorhabditis elegans
    • Wang, J. Kim, S. K. Global analysis of dauer gene expression in Caenorhabditis elegans. Development 130, 1621-1634 (2003).
    • (2003) Development , vol.130 , pp. 1621-1634
    • Wang, J.1    Kim, S.K.2
  • 6
    • 0037112907 scopus 로고    scopus 로고
    • Nutrient control of gene expression in Drosophila: Microarray analysis of starvation and sugar-dependent response
    • Zinke, I., Schutz, C. S., Katzenberger, J. D., Bauer, M. Pankratz, M. J. Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response. EMBO J. 21, 6162-6173 (2002).
    • (2002) EMBO J. , vol.21 , pp. 6162-6173
    • Zinke, I.1    Schutz, C.S.2    Katzenberger, J.D.3    Bauer, M.4    Pankratz, M.J.5
  • 7
    • 3843070757 scopus 로고    scopus 로고
    • Starvation response in mouse liver shows strong correlation with life-span-prolonging processes
    • Bauer, M. et al. Starvation response in mouse liver shows strong correlation with life-span-prolonging processes. Physiol. Genom. 17, 230-244 (2004).
    • (2004) Physiol. Genom. , vol.17 , pp. 230-244
    • Bauer, M.1
  • 8
    • 0037162295 scopus 로고    scopus 로고
    • Inducible antibacterial defense system in C
    • Mallo, G. V. et al. Inducible antibacterial defense system in C. elegans. Curr. Biol. 12, 1209-1214 (2002).
    • (2002) Elegans. Curr. Biol. , vol.12 , pp. 1209-1214
    • Mallo, G.V.1
  • 9
    • 33747375161 scopus 로고    scopus 로고
    • PTARGET: A web server for predicting protein subcellular localization
    • Guda, C. pTARGET: a web server for predicting protein subcellular localization. Nucleic Acids Res. 34, W210-W213 (2006).
    • (2006) Nucleic Acids Res. , vol.34
    • Guda, C.1
  • 10
    • 27744493876 scopus 로고    scopus 로고
    • PTARGET [corrected] A New Method for Predicting Protein Subcellular Localization in Eukaryotes
    • Guda, C. Subramaniam, S. pTARGET [corrected] a new method for predicting protein subcellular localization in eukaryotes. Bioinformatics 21, 3963-3969 (2005).
    • (2005) Bioinformatics , vol.21 , pp. 3963-3969
    • Guda, C.1    Subramaniam, S.2
  • 11
    • 33947158693 scopus 로고    scopus 로고
    • Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle
    • Schroeder, L. K. et al. Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Mol. Biol. Cell 18, 995-1008 (2007).
    • (2007) Mol. Biol. Cell , vol.18 , pp. 995-1008
    • Schroeder, L.K.1
  • 12
    • 67650594823 scopus 로고    scopus 로고
    • A multiparameter network reveals extensive divergence between Celegans bHLH transcription factors
    • Grove, C. A. et al. A multiparameter network reveals extensive divergence between Celegans bHLH transcription factors. Cell 138, 314-327 (2009).
    • (2009) Cell , vol.138 , pp. 314-327
    • Grove, C.A.1
  • 13
    • 70350365111 scopus 로고    scopus 로고
    • Celegans major fats are stored in vesicles distinct from lysosome-related organelles
    • O'Rourke, E. J., Soukas, A. A., Carr, C. E. Ruvkun, G. Celegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metab. 10, 430-435 (2009).
    • (2009) Cell Metab. , vol.10 , pp. 430-435
    • O'Rourke, E.J.1    Soukas, A.A.2    Carr, C.E.3    Ruvkun, G.4
  • 14
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • Ashra-, K. et al. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421, 268-272 (2003).
    • (2003) Nature , vol.421 , pp. 268-272
    • Ashra, K.1
  • 15
    • 67749122634 scopus 로고    scopus 로고
    • A gene network regulating lysosomal biogenesis and function
    • Sardiello, M. et al. A gene network regulating lysosomal biogenesis and function. Science 325, 473-477 (2009).
    • (2009) Science , vol.325 , pp. 473-477
    • Sardiello, M.1
  • 16
    • 80955177196 scopus 로고    scopus 로고
    • TFEB links autophagy to lysosomal biogenesis
    • Settembre, C. et al. TFEB links autophagy to lysosomal biogenesis. Science 332, 1429-1433 (2011).
    • (2011) Science , vol.332 , pp. 1429-1433
    • Settembre, C.1
  • 17
    • 72549095406 scopus 로고    scopus 로고
    • Regulation mechanisms and signaling pathways of autophagy
    • He, C. Klionsky, D. J. Regulation mechanisms and signaling pathways of autophagy. Annu. Rev. Genet. 43, 67-93 (2009).
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 67-93
    • He, C.1    Klionsky, D.J.2
  • 18
    • 36248964713 scopus 로고    scopus 로고
    • Gene activities that mediate increased life span of Celegans insulin-like signaling mutants
    • Samuelson, A. V., Carr, C. E. Ruvkun, G. Gene activities that mediate increased life span of Celegans insulin-like signaling mutants. Genes Dev. 21, 2976-2994 (2007).
    • (2007) Genes Dev. , vol.21 , pp. 2976-2994
    • Samuelson, A.V.1    Carr, C.E.2    Ruvkun, G.3
  • 19
    • 0042691506 scopus 로고    scopus 로고
    • Autophagy genes are essential for dauer development and life-span extension in C. elegans
    • Melendez, A. et al. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301, 1387-1391 (2003).
    • (2003) Science , vol.301 , pp. 1387-1391
    • Melendez, A.1
  • 20
    • 40149105890 scopus 로고    scopus 로고
    • A role for autophagy in the extension of lifespan by dietary restriction in C. elegans
    • Hansen, M. et al. A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet 4, e24 (2008).
    • (2008) PLoS Genet , vol.4
    • Hansen, M.1
  • 21
    • 58149339613 scopus 로고    scopus 로고
    • Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
    • Narbonne, P. Roy, R. Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457, 210-214 (2009).
    • (2009) Nature , vol.457 , pp. 210-214
    • Narbonne, P.1    Roy, R.2
  • 22
    • 65349113758 scopus 로고    scopus 로고
    • IRE-1 and HSP-4 Contribute to energy homeostasis via fasting-induced lipases
    • Jo, H., Shim, J., Lee, J. H., Lee, J. Kim, J. B. IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Cell Metab. 9, 440-448 (2009).
    • (2009) C. Elegans. Cell Metab , vol.9 , pp. 440-448
    • Jo, H.1    Shim, J.2    Lee, J.H.3    Lee, J.4    Kim, J.B.5
  • 23
    • 80052756899 scopus 로고    scopus 로고
    • Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C. elegans
    • Tan, K. T., Luo, S. C., Ho, W. Z. Lee, Y. H. Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C. elegans. Cell Metab. 14, 390-402 (2011).
    • (2011) Cell Metab. , vol.14 , pp. 390-402
    • Tan, K.T.1    Luo, S.C.2    Ho, W.Z.3    Lee, Y.H.4
  • 24
    • 26444442036 scopus 로고    scopus 로고
    • A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49
    • Van Gilst, M. R., Hadjivassiliou, H. Yamamoto, K. R. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proc. Natl Acad. Sci. USA 102, 13496-13501 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 13496-13501
    • Van Gilst, M.R.1    Hadjivassiliou, H.2    Yamamoto, K.R.3
  • 25
    • 77954488637 scopus 로고    scopus 로고
    • Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
    • Walker, A. K. et al. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 24, 1403-1417 (2010).
    • (2010) Genes Dev. , vol.24 , pp. 1403-1417
    • Walker, A.K.1
  • 26
    • 84857997408 scopus 로고    scopus 로고
    • A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
    • Settembre, C. et al. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J. 31, 1095-1108 (2012).
    • (2012) EMBO J. , vol.31 , pp. 1095-1108
    • Settembre, C.1
  • 27
    • 84862539692 scopus 로고    scopus 로고
    • The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis
    • Roczniak-Ferguson, A. et al. The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Sci. Signal 5, ra42 (2012).
    • (2012) Sci. Signal , vol.5
    • Roczniak-Ferguson, A.1
  • 28
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quanti-cation in real-time RT-PCR
    • Pfaf-, M. W. A new mathematical model for relative quanti-cation in real-time RT-PCR. Nucleic Acids Res. 29, e45 (2001).
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaf, M.W.1
  • 29
    • 33644555529 scopus 로고    scopus 로고
    • PwormgatePro enables promoter-driven knockdown by hairpin RNA interference of muscle and neuronal gene products in Caenorhabditis elegans
    • Briese, M., Esmaeili, B., Johnson, N. M. Sattelle, D. B. pWormgatePro enables promoter-driven knockdown by hairpin RNA interference of muscle and neuronal gene products in Caenorhabditis elegans. Invert Neurosci. 6, 5-12 (2006).
    • (2006) Invert Neurosci , vol.6 , pp. 5-12
    • Briese, M.1    Esmaeili, B.2    Johnson, N.M.3    Sattelle, D.B.4
  • 30
    • 0037197901 scopus 로고    scopus 로고
    • Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans
    • Watts, J. L. Browse, J. Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 99, 5854-5859 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 5854-5859
    • Watts, J.L.1    Browse, J.2
  • 31
  • 32
    • 42049088684 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans
    • Mukhopadhyay, A., Deplancke, B., Walhout, A. J. Tissenbaum, H. A. Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans. Nat. Protoc. 3, 698-709 (2008).
    • (2008) Nat. Protoc. , vol.3 , pp. 698-709
    • Mukhopadhyay, A.1    Deplancke, B.2    Walhout, A.J.3    Tissenbaum, H.A.4
  • 33
    • 84863997137 scopus 로고    scopus 로고
    • LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis
    • Liu, B., Du, H., Rutkowski, R., Gartner, A. Wang, X. LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis. Science 337, 351-354 (2012).
    • (2012) Science , vol.337 , pp. 351-354
    • Liu, B.1    Du, H.2    Rutkowski, R.3    Gartner, A.4    Wang, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.