-
1
-
-
11344268432
-
Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS
-
Adelman, K., et al. 2005. Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS. Mol. Cell 17:103-112.
-
(2005)
Mol. Cell
, vol.17
, pp. 103-112
-
-
Adelman, K.1
-
2
-
-
33846590977
-
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
-
Benetti, R., M. Garcia-Cao, and M. A. Blasco. 2007. Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat. Genet. 39:243-250.
-
(2007)
Nat. Genet.
, vol.39
, pp. 243-250
-
-
Benetti, R.1
Garcia-Cao, M.2
Blasco, M.A.3
-
3
-
-
34548827379
-
Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination
-
Benetti, R., et al. 2007. Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination. J. Cell Biol. 178:925-936.
-
(2007)
J. Cell Biol.
, vol.178
, pp. 925-936
-
-
Benetti, R.1
-
4
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird, A. P. 1986. CpG-rich islands and the function of DNA methylation. Nature 321:209-213.
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
5
-
-
77951182263
-
Subunit composition and substrate specificity of a MOFcontaining histone acetyltransferase distinct from the male-specific lethal (MSL) complex
-
Cai, Y., et al. 2010. Subunit composition and substrate specificity of a MOFcontaining histone acetyltransferase distinct from the male-specific lethal (MSL) complex. J. Biol. Chem. 285:4268-4272.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 4268-4272
-
-
Cai, Y.1
-
6
-
-
34147096005
-
Epigenetic profiling of multidrug-resistant human MCF-7 breast adenocarcinoma cells reveals novel hyper- and hypomethylated targets
-
Chekhun, V. F., N. Y. Lukyanova, O. Kovalchuk, V. P. Tryndyak, and I. P. Pogribny. 2007. Epigenetic profiling of multidrug-resistant human MCF-7 breast adenocarcinoma cells reveals novel hyper- and hypomethylated targets. Mol. Cancer Ther. 6:1089-1098.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 1089-1098
-
-
Chekhun, V.F.1
Lukyanova, N.Y.2
Kovalchuk, O.3
Tryndyak, V.P.4
Pogribny, I.P.5
-
7
-
-
34547563511
-
Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation
-
Cheng, B., and D. H. Price. 2007. Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation. J. Biol. Chem. 282:21901-21912.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 21901-21912
-
-
Cheng, B.1
Price, D.H.2
-
8
-
-
33645906532
-
Methylation of the ASC gene promoter is associated with aggressive prostate cancer
-
Collard, R. L., N. S. Harya, F. A. Monzon, C. E. Maier, and D. S. O'Keefe. 2006. Methylation of the ASC gene promoter is associated with aggressive prostate cancer. Prostate 66:687-695.
-
(2006)
Prostate
, vol.66
, pp. 687-695
-
-
Collard, R.L.1
Harya, N.S.2
Monzon, F.A.3
Maier, C.E.4
O'Keefe, D.S.5
-
9
-
-
77952692464
-
PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression
-
Congdon, L. M., S. I. Houston, C. S. Veerappan, T. M. Spektor, and J. C. Rice. 2010. PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression. J. Cell. Biochem. 110:609-619.
-
(2010)
J. Cell. Biochem.
, vol.110
, pp. 609-619
-
-
Congdon, L.M.1
Houston, S.I.2
Veerappan, C.S.3
Spektor, T.M.4
Rice, J.C.5
-
10
-
-
0033676843
-
TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers
-
Conway, K. E., et al. 2000. TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers. Cancer Res. 60:6236-6242.
-
(2000)
Cancer Res
, vol.60
, pp. 6236-6242
-
-
Conway, K.E.1
-
11
-
-
57849109058
-
Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters
-
Core, L. J., J. J. Waterfall, and J. T. Lis. 2008. Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science 322:1845-1848.
-
(2008)
Science
, vol.322
, pp. 1845-1848
-
-
Core, L.J.1
Waterfall, J.J.2
Lis, J.T.3
-
12
-
-
44049088029
-
Bromodomain 4 activation predicts breast cancer survival
-
Crawford, N. P., et al. 2008. Bromodomain 4 activation predicts breast cancer survival. Proc. Natl. Acad. Sci. U. S. A. 105:6380-6385.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 6380-6385
-
-
Crawford, N.P.1
-
13
-
-
0041806599
-
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
-
Dey, A., F. Chitsaz, A. Abbasi, T. Misteli, and K. Ozato. 2003. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc. Natl. Acad. Sci. U. S. A. 100:8758-8763.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 8758-8763
-
-
Dey, A.1
Chitsaz, F.2
Abbasi, A.3
Misteli, T.4
Ozato, K.5
-
14
-
-
20444397430
-
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF
-
Dou, Y., et al. 2005. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell 121:873-885.
-
(2005)
Cell
, vol.121
, pp. 873-885
-
-
Dou, Y.1
-
15
-
-
33846444355
-
Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment
-
Egger, G., A. M. Aparicio, S. G. Escobar, and P. A. Jones. 2007. Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment. Cancer Res. 67:346-353.
-
(2007)
Cancer Res
, vol.67
, pp. 346-353
-
-
Egger, G.1
Aparicio, A.M.2
Escobar, S.G.3
Jones, P.A.4
-
16
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga, M. F., et al. 2005. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat. Genet. 37:391-400.
-
(2005)
Nat. Genet.
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
-
17
-
-
0035180206
-
BRD4 bromodomain gene rearrangement in aggressive carcinoma with translocation t(15;19)
-
French, C. A., et al. 2001. BRD4 bromodomain gene rearrangement in aggressive carcinoma with translocation t(15;19). Am. J. Pathol. 159:1987-1992.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 1987-1992
-
-
French, C.A.1
-
18
-
-
47549090254
-
NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly
-
Gilchrist, D. A., et al. 2008. NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly. Genes Dev. 22:1921-1933.
-
(2008)
Genes Dev
, vol.22
, pp. 1921-1933
-
-
Gilchrist, D.A.1
-
19
-
-
58349085943
-
Promoter proximal pausing on genes in metazoans
-
Gilmour, D. S. 2009. Promoter proximal pausing on genes in metazoans. Chromosoma 118:1-10.
-
(2009)
Chromosoma
, vol.118
, pp. 1-10
-
-
Gilmour, D.S.1
-
20
-
-
20244376464
-
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
-
Gonzalo, S., et al. 2005. Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat. Cell Biol. 7:420-428.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 420-428
-
-
Gonzalo, S.1
-
21
-
-
0030868694
-
Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation
-
Graff, J. R., J. G. Herman, S. Myohanen, S. B. Baylin, and P. M. Vertino. 1997. Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation. J. Biol. Chem. 272:22322-22329.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22322-22329
-
-
Graff, J.R.1
Herman, J.G.2
Myohanen, S.3
Baylin, S.B.4
Vertino, P.M.5
-
22
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells
-
Guenther, M. G., S. S. Levine, L. A. Boyer, R. Jaenisch, and R. A. Young. 2007. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130:77-88.
-
(2007)
Cell
, vol.130
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
23
-
-
34250213859
-
DNA methylation as a therapeutic target in cancer
-
Issa, J. P. 2007. DNA methylation as a therapeutic target in cancer. Clin. Cancer Res. 13:1634-1637.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 1634-1637
-
-
Issa, J.P.1
-
24
-
-
70949097382
-
Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation
-
Jacinto, F. V., E. Ballestar, and M. Esteller. 2009. Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation. Oncogene 28:4212-4224.
-
(2009)
Oncogene
, vol.28
, pp. 4212-4224
-
-
Jacinto, F.V.1
Ballestar, E.2
Esteller, M.3
-
25
-
-
23744514308
-
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
-
Jang, M. K., et al. 2005. The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. Mol. Cell 19:523-534.
-
(2005)
Mol. Cell
, vol.19
, pp. 523-534
-
-
Jang, M.K.1
-
26
-
-
34548603504
-
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
-
Jia, D., R. Z. Jurkowska, X. Zhang, A. Jeltsch, and X. Cheng. 2007. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature 449:248-251.
-
(2007)
Nature
, vol.449
, pp. 248-251
-
-
Jia, D.1
Jurkowska, R.Z.2
Zhang, X.3
Jeltsch, A.4
Cheng, X.5
-
27
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
Jones, P. A., and D. Takai. 2001. The role of DNA methylation in mammalian epigenetics. Science 293:1068-1070.
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
-
28
-
-
77955459115
-
Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy
-
Kagey, J. D., P. Kapoor-Vazirani, M. T. McCabe, D. R. Powell, and P. M. Vertino. 2010. Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy. Mol. Cancer Res. 8:1048-1059.
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 1048-1059
-
-
Kagey, J.D.1
Kapoor-Vazirani, P.2
McCabe, M.T.3
Powell, D.R.4
Vertino, P.M.5
-
29
-
-
53049099107
-
Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity
-
Kapoor-Vazirani, P., J. D. Kagey, D. R. Powell, and P. M. Vertino. 2008. Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity. Cancer Res. 68:6810-6821.
-
(2008)
Cancer Res
, vol.68
, pp. 6810-6821
-
-
Kapoor-Vazirani, P.1
Kagey, J.D.2
Powell, D.R.3
Vertino, P.M.4
-
30
-
-
77955423898
-
Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain
-
Kim, D., B. J. Blus, V. Chandra, P. Huang, F. Rastinejad, and S. Khorasanizadeh. 2010. Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain. Nat. Struct. Mol. Biol. 17:1027-1029.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1027-1029
-
-
Kim, D.1
Blus, B.J.2
Chandra, V.3
Huang, P.4
Rastinejad, F.5
Khorasanizadeh, S.6
-
31
-
-
0038118337
-
Effects of methylation on expression of TMS1/ASC in human breast cancer cells
-
Levine, J. J., K. M. Stimson-Crider, and P. M. Vertino. 2003. Effects of methylation on expression of TMS1/ASC in human breast cancer cells. Oncogene 22:3475-3488.
-
(2003)
Oncogene
, vol.22
, pp. 3475-3488
-
-
Levine, J.J.1
Stimson-Crider, K.M.2
Vertino, P.M.3
-
32
-
-
70350012477
-
Two mammalian MOF complexes regulate transcription activation by distinct mechanisms
-
Li, X., L. Wu, C. A. Corsa, S. Kunkel, and Y. Dou. 2009. Two mammalian MOF complexes regulate transcription activation by distinct mechanisms. Mol. Cell 36:290-301.
-
(2009)
Mol. Cell
, vol.36
, pp. 290-301
-
-
Li, X.1
Wu, L.2
Corsa, C.A.3
Kunkel, S.4
Dou, Y.5
-
33
-
-
0029011873
-
Purification of P-TEFb, a transcription factor required for the transition into productive elongation
-
Marshall, N. F., and D. H. Price. 1995. Purification of P-TEFb, a transcription factor required for the transition into productive elongation. J. Biol. Chem. 270:12335-12338.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12335-12338
-
-
Marshall, N.F.1
Price, D.H.2
-
34
-
-
0033607768
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
-
Masumoto, J., et al. 1999. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J. Biol. Chem. 274:33835-33838.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33835-33838
-
-
Masumoto, J.1
-
35
-
-
77950862656
-
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
-
Matsui, T., et al. 2010. Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature 464:927-931.
-
(2010)
Nature
, vol.464
, pp. 927-931
-
-
Matsui, T.1
-
36
-
-
67449113768
-
Cancer DNA methylation: molecular mechanisms and clinical implications
-
McCabe, M. T., J. C. Brandes, and P. M. Vertino. 2009. Cancer DNA methylation: molecular mechanisms and clinical implications. Clin. Cancer Res. 15:3927-3937.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 3927-3937
-
-
McCabe, M.T.1
Brandes, J.C.2
Vertino, P.M.3
-
37
-
-
1442277112
-
TMS1/ASC: the cancer connection
-
McConnell, B. B., and P. M. Vertino. 2004. TMS1/ASC: the cancer connection. Apoptosis 9:5-18.
-
(2004)
Apoptosis
, vol.9
, pp. 5-18
-
-
McConnell, B.B.1
Vertino, P.M.2
-
38
-
-
33645751058
-
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
-
McGarvey, K. M., et al. 2006. Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Res. 66:3541-3549.
-
(2006)
Cancer Res
, vol.66
, pp. 3541-3549
-
-
McGarvey, K.M.1
-
39
-
-
33644870525
-
Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila
-
Mendjan, S., et al. 2006. Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. Mol. Cell 21:811-823.
-
(2006)
Mol. Cell
, vol.21
, pp. 811-823
-
-
Mendjan, S.1
-
40
-
-
78650361859
-
Structural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono or dimethyl lysine 20 on histone H4
-
Moore, S. A., Y. Ferhatoglu, Y. Jia, R. A. Al-Jiab, and M. J. Scott. 2010. Structural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono or dimethyl lysine 20 on histone H4. J. Biol. Chem. 285:40879-40890.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 40879-40890
-
-
Moore, S.A.1
Ferhatoglu, Y.2
Jia, Y.3
Al-Jiab, R.A.4
Scott, M.J.5
-
41
-
-
36549061004
-
RNA polymerase is poised for activation across the genome
-
Muse, G. W., et al. 2007. RNA polymerase is poised for activation across the genome. Nat. Genet. 39:1507-1511.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1507-1511
-
-
Muse, G.W.1
-
42
-
-
45849129033
-
Promoter-proximal Pol II: when stalling speeds things up
-
Nechaev, S., and K. Adelman. 2008. Promoter-proximal Pol II: when stalling speeds things up. Cell Cycle 7:1539-1544.
-
(2008)
Cell Cycle
, vol.7
, pp. 1539-1544
-
-
Nechaev, S.1
Adelman, K.2
-
43
-
-
18444392703
-
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin
-
Nishioka, K., et al. 2002. PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. Mol. Cell 9:1201-1213.
-
(2002)
Mol. Cell
, vol.9
, pp. 1201-1213
-
-
Nishioka, K.1
-
44
-
-
0028318783
-
Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells
-
Ottaviano, Y. L., et al. 1994. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res. 54:2552-2555.
-
(1994)
Cancer Res
, vol.54
, pp. 2552-2555
-
-
Ottaviano, Y.L.1
-
45
-
-
62449327005
-
Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells
-
Parsons, M. J., P. Patel, D. J. Brat, L. Colbert, and P. M. Vertino. 2009. Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells. Cancer Res. 69:1706-1711.
-
(2009)
Cancer Res
, vol.69
, pp. 1706-1711
-
-
Parsons, M.J.1
Patel, P.2
Brat, D.J.3
Colbert, L.4
Vertino, P.M.5
-
46
-
-
33747857815
-
Dual role of TMS1/ASC in death receptor signaling
-
Parsons, M. J., and P. M. Vertino. 2006. Dual role of TMS1/ASC in death receptor signaling. Oncogene 25:6948-6958.
-
(2006)
Oncogene
, vol.25
, pp. 6948-6958
-
-
Parsons, M.J.1
Vertino, P.M.2
-
47
-
-
37549014575
-
Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle
-
Pesavento, J. J., H. Yang, N. L. Kelleher, and C. A. Mizzen. 2008. Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle. Mol. Cell. Biol. 28:468-486.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 468-486
-
-
Pesavento, J.J.1
Yang, H.2
Kelleher, N.L.3
Mizzen, C.A.4
-
48
-
-
39649119288
-
The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma
-
Pfister, S., et al. 2008. The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma. Int. J. Cancer 122:1207-1213.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 1207-1213
-
-
Pfister, S.1
-
49
-
-
33646142159
-
Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats
-
Pogribny, I. P., et al. 2006. Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats. Carcinogenesis 27:1180-1186.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1180-1186
-
-
Pogribny, I.P.1
-
50
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta, G., et al. 2004. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev. 18:1251-1262.
-
(2004)
Genes Dev
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
-
51
-
-
48749102722
-
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse
-
Schotta, G., et al. 2008. A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev. 22:2048-2061.
-
(2008)
Genes Dev
, vol.22
, pp. 2048-2061
-
-
Schotta, G.1
-
52
-
-
27144546434
-
A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16
-
Smith, E. R., et al. 2005. A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. Mol. Cell. Biol. 25:9175-9188.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9175-9188
-
-
Smith, E.R.1
-
53
-
-
0037085272
-
Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG islandlocalized changes in chromatin architecture
-
Stimson, K. M., and P. M. Vertino. 2002. Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG islandlocalized changes in chromatin architecture. J. Biol. Chem. 277:4951-4958.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4951-4958
-
-
Stimson, K.M.1
Vertino, P.M.2
-
54
-
-
4644314826
-
Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma
-
Stone, A. R., et al. 2004. Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma. Am. J. Pathol. 165:1151-1161.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 1151-1161
-
-
Stone, A.R.1
-
55
-
-
77949901729
-
Human negative elongation factor activates transcription and regulates alternative transcription initiation
-
Sun, J., and R. Li. 2010. Human negative elongation factor activates transcription and regulates alternative transcription initiation. J. Biol. Chem. 285:6443-6452.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6443-6452
-
-
Sun, J.1
Li, R.2
-
56
-
-
22544480772
-
hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells
-
Taipale, M., et al. 2005. hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells. Mol. Cell. Biol. 25: 6798-6810.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6798-6810
-
-
Taipale, M.1
-
57
-
-
70350069495
-
The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands
-
Takeshima, H., S. Yamashita, T. Shimazu, T. Niwa, and T. Ushijima. 2009. The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands. Genome Res. 19:1974-1982.
-
(2009)
Genome Res
, vol.19
, pp. 1974-1982
-
-
Takeshima, H.1
Yamashita, S.2
Shimazu, T.3
Niwa, T.4
Ushijima, T.5
-
58
-
-
33747881750
-
The general transcription machinery and general cofactors
-
Thomas, M. C., and C. M. Chiang. 2006. The general transcription machinery and general cofactors. Crit. Rev. Biochem. Mol. Biol. 41:105-178.
-
(2006)
Crit. Rev. Biochem. Mol. Biol.
, vol.41
, pp. 105-178
-
-
Thomas, M.C.1
Chiang, C.M.2
-
59
-
-
58149329023
-
Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer
-
Van Den Broeck, A., et al. 2008. Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer. Clin. Cancer Res. 14:7237-7245.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 7237-7245
-
-
Van Den Broeck, A.1
-
60
-
-
56449131444
-
Chromatin meets RNA polymerase II
-
Venters, B. J., and B. F. Pugh. 2007. Chromatin meets RNA polymerase II. Genome Biol. 8:319.
-
(2007)
Genome Biol
, vol.8
, pp. 319
-
-
Venters, B.J.1
Pugh, B.F.2
-
61
-
-
0032534814
-
Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro
-
Wada, T., T. Takagi, Y. Yamaguchi, D. Watanabe, and H. Handa. 1998. Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro. EMBO J. 17:7395-7403.
-
(1998)
EMBO J
, vol.17
, pp. 7395-7403
-
-
Wada, T.1
Takagi, T.2
Yamaguchi, Y.3
Watanabe, D.4
Handa, H.5
-
62
-
-
69449102464
-
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
-
Wang, Z., et al. 2009. Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138:1019-1031.
-
(2009)
Cell
, vol.138
, pp. 1019-1031
-
-
Wang, Z.1
-
63
-
-
0037609009
-
NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila
-
Wu, C. H., et al. 2003. NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila. Genes Dev. 17:1402-1414.
-
(2003)
Genes Dev
, vol.17
, pp. 1402-1414
-
-
Wu, C.H.1
-
64
-
-
30744449491
-
P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation
-
Yamada, T., et al. 2006. P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation. Mol. Cell 21:227-237.
-
(2006)
Mol. Cell
, vol.21
, pp. 227-237
-
-
Yamada, T.1
-
65
-
-
0033515521
-
NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
-
Yamaguchi, Y., et al. 1999. NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell 97: 41-51.
-
(1999)
Cell
, vol.97
, pp. 41-51
-
-
Yamaguchi, Y.1
-
66
-
-
65249157999
-
The multiple facets of histone H4-lysine 20 methylation
-
Yang, H., and C. A. Mizzen. 2009. The multiple facets of histone H4-lysine 20 methylation. Biochem. Cell Biol. 87:151-161.
-
(2009)
Biochem. Cell Biol.
, vol.87
, pp. 151-161
-
-
Yang, H.1
Mizzen, C.A.2
-
67
-
-
45549088504
-
Preferential dimethylation of histone H4 lysine 20 by Suv4-20
-
Yang, H., et al. 2008. Preferential dimethylation of histone H4 lysine 20 by Suv4-20. J. Biol. Chem. 283:12085-12092.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 12085-12092
-
-
Yang, H.1
-
68
-
-
33847189172
-
Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo
-
Zeitlinger, J., et al. 2007. Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo. Genes Dev. 21:385-390.
-
(2007)
Genes Dev
, vol.21
, pp. 385-390
-
-
Zeitlinger, J.1
-
69
-
-
70149112313
-
Histone crosstalk between H3S10ph and H4K16ac generates a histone code that mediates transcription elongation
-
Zippo, A., et al. 2009. Histone crosstalk between H3S10ph and H4K16ac generates a histone code that mediates transcription elongation. Cell 138: 1122-1136.
-
(2009)
Cell
, vol.138
, pp. 1122-1136
-
-
Zippo, A.1
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