Precision cancer mouse models through genome editing with CRISPR-Cas9

Genome Medicine

Volumn 7, Issue 1, 2015, Pages

  Mou, Haiwei ^a   Kennedy, Zachary ^a   Anderson, Daniel G ^b,c,d   Yin, Hao ^b   Xue, Wen ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

^d HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRIZOTINIB; DOXORUBICIN; GENOMIC DNA; IMATINIB;

ACCURACY; ACUTE MYELOBLASTIC LEUKEMIA; ARTICLE; B CELL LYMPHOMA; CANCER CHEMOTHERAPY; CANCER GENETICS; CANCER GROWTH; CANCER RESISTANCE; CHROMOSOME REARRANGEMENT; CHRONIC MYELOID LEUKEMIA; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; DRUG EFFECT; FUNCTIONAL GENOMICS; GENE DELETION; GENE SEQUENCE; GENE TARGETING; GENETIC ENGINEERING; GENOME ANALYSIS; GERMLINE MUTATION; HUMAN; LUNG CANCER; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR EVOLUTION; MOUSE MODEL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; TARGETED GENE REPAIR;

EID: 84939252101     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/s13073-015-0178-7     Document Type: Article

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