CRISPRseek: A Bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Zhu, Lihua J ^a   Holmes, Benjamin R ^b   Aronin, Neil ^a   Brodsky, Michael H ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; GUIDE RNA; HUNTINGTIN; RESTRICTION ENDONUCLEASE; CRISPR ASSOCIATED PROTEIN; HTT PROTEIN, HUMAN; NERVE PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COMPUTER LANGUAGE; COMPUTER PROGRAM; CONTROLLED STUDY; GENE TARGETING; GENOME ANALYSIS; HUMAN; INTERNET; PROTEIN CLEAVAGE; RESTRICTION MAPPING; RNA EDITING; BIOLOGY; CRISPR CAS SYSTEM; ENZYME SPECIFICITY; GENETICS; GENOMICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; SEQUENCE HOMOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

BASE SEQUENCE; COMPUTATIONAL BIOLOGY; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; GENOMICS; HUMANS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA EDITING; RNA, GUIDE; SEQUENCE HOMOLOGY, NUCLEIC ACID; SOFTWARE; SUBSTRATE SPECIFICITY;

EID: 84907573408     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108424     Document Type: Article

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