-
1
-
-
77955841149
-
Collaboration and competition between DNA double-strand break repair pathways
-
Kass,E.M. and Jasin,M. (2010) Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett., 584, 3703-3708.
-
(2010)
FEBS Lett.
, vol.584
, pp. 3703-3708
-
-
Kass, E.M.1
Jasin, M.2
-
2
-
-
0024805622
-
Homologous recombination in mammalian cells
-
Bollag,R.J., Waldman,A.S. and Liskay,R.M. (1989) Homologous recombination in mammalian cells. Annu. Rev. Genet., 23, 199-225.
-
(1989)
Annu. Rev. Genet.
, vol.23
, pp. 199-225
-
-
Bollag, R.J.1
Waldman, A.S.2
Liskay, R.M.3
-
3
-
-
33847682924
-
Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases
-
Moehle,E.A., Rock,J.M., Lee,Y.-L., Jouvenot,Y., DeKelver,R.C., Gregory,P.D., Urnov,F.D. and Holmes,M.C. (2007) Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases. Proc. Natl. Acad. Sci. U.S.A., 104, 3055-3060.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 3055-3060
-
-
Moehle, E.A.1
Rock, J.M.2
Lee, Y.-L.3
Jouvenot, Y.4
DeKelver, R.C.5
Gregory, P.D.6
Urnov, F.D.7
Holmes, M.C.8
-
4
-
-
0026753186
-
Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus
-
Deng,C. and Capecchi,M.R. (1992) Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol. Cell. Biol., 12, 3365-3371.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 3365-3371
-
-
Deng, C.1
Capecchi, M.R.2
-
5
-
-
70249114821
-
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
-
Hockemeyer,D., Soldner,F., Beard,C., Gao,Q., Mitalipova,M., DeKelver,R.C., Katibah,G.E., Amora,R., Boydston,E.A., Zeitler,B. et al. (2009) Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat. Biotechnol., 27, 851-857.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 851-857
-
-
Hockemeyer, D.1
Soldner, F.2
Beard, C.3
Gao, Q.4
Mitalipova, M.5
DeKelver, R.C.6
Katibah, G.E.7
Amora, R.8
Boydston, E.A.9
Zeitler, B.10
-
6
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz,F., Dutriaux,A., Lengauer,C., Waldman,T., Zhou,S., Brown,J.P., Sedivy,J.M., Kinzler,K.W. and Vogelstein,B. (1998) Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science, 282, 1497-1501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
7
-
-
58549095879
-
Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses
-
Di Nicolantonio,F., Arena,S., Gallicchio,M., Zecchin,D., Martini,M., Flonta,S.E., Stella,G.M., Lamba,S., Cancelliere,C., Russo,M. et al. (2008) Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses. Proc. Natl. Acad. Sci. U.S.A., 105, 20864-20869.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 20864-20869
-
-
Di Nicolantonio, F.1
Arena, S.2
Gallicchio, M.3
Zecchin, D.4
Martini, M.5
Flonta, S.E.6
Stella, G.M.7
Lamba, S.8
Cancelliere, C.9
Russo, M.10
-
8
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang,H., Yang,H., Shivalila,C.S., Dawlaty,M.M., Cheng,A.W., Zhang,F. and Jaenisch,R. (2013) One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell, 153, 910-918.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
9
-
-
77955867185
-
Genome editing with engineered zinc finger nucleases
-
Urnov,F.D., Rebar,E.J., Holmes,M.C., Zhang,H.S. and Gregory,P.D. (2010) Genome editing with engineered zinc finger nucleases. Nat. Rev. Genet., 11, 636-646.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 636-646
-
-
Urnov, F.D.1
Rebar, E.J.2
Holmes, M.C.3
Zhang, H.S.4
Gregory, P.D.5
-
10
-
-
84886824017
-
Rapid, modular and reliable construction of complex mammalian gene circuits
-
Guye,P., Li,Y., Wroblewska,L., Duportet,X. and Weiss,R. (2013) Rapid, modular and reliable construction of complex mammalian gene circuits. Nucleic Acids Res., 41, e156.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. e156
-
-
Guye, P.1
Li, Y.2
Wroblewska, L.3
Duportet, X.4
Weiss, R.5
-
11
-
-
0031962185
-
Gene conversion tracts from double-strand break repair in mammalian cells
-
Elliott,B., Richardson,C., Winderbaum,J., Nickoloff,J.A. and Jasin,M. (1998) Gene conversion tracts from double-strand break repair in mammalian cells. Mol. Cell. Biol., 18, 93-101.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 93-101
-
-
Elliott, B.1
Richardson, C.2
Winderbaum, J.3
Nickoloff, J.A.4
Jasin, M.5
-
12
-
-
0034749283
-
Stimulation of homologous recombination through targeted cleavage by chimeric nucleases
-
Bibikova,M., Carroll,D., Segal,D.J., Trautman,J.K., Smith,J., Kim,Y.G. and Chandrasegaran,S. (2001) Stimulation of homologous recombination through targeted cleavage by chimeric nucleases. Mol. Cell. Biol., 21, 289-297.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 289-297
-
-
Bibikova, M.1
Carroll, D.2
Segal, D.J.3
Trautman, J.K.4
Smith, J.5
Kim, Y.G.6
Chandrasegaran, S.7
-
13
-
-
77955126358
-
Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology
-
Orlando,S.J., Santiago,Y., DeKelver,R.C., Freyvert,Y., Boydston,E.A., Moehle,E.A., Choi,V.M., Gopalan,S.M., Lou,J.F., Li,J. et al. (2010) Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology. Nucleic Acids Res., 38, e152.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. e152
-
-
Orlando, S.J.1
Santiago, Y.2
DeKelver, R.C.3
Freyvert, Y.4
Boydston, E.A.5
Moehle, E.A.6
Choi, V.M.7
Gopalan, S.M.8
Lou, J.F.9
Li, J.10
-
14
-
-
84881060423
-
Donor DNA utilization during gene targeting with zinc-finger nucleases
-
Beumer,K.J., Trautman,J.K., Mukherjee,K. and Carroll,D. (2013) Donor DNA utilization during gene targeting with zinc-finger nucleases. G3 Genes|Genomes|Genetics, 3, 657-664.
-
(2013)
G3 Genes|Genomes|Genetics
, vol.3
, pp. 657-664
-
-
Beumer, K.J.1
Trautman, J.K.2
Mukherjee, K.3
Carroll, D.4
-
15
-
-
84885157177
-
Optimization of scarless human stem cell genome editing
-
Yang,L., Guell,M., Byrne,S., Yang,J.L., De Los Angeles,A., Mali,P., Aach,J., Kim-Kiselak,C., Briggs,A.W., Rios,X. et al. (2013) Optimization of scarless human stem cell genome editing. Nucleic Acids Res., 41, 9049-9061.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 9049-9061
-
-
Yang, L.1
Guell, M.2
Byrne, S.3
Yang, J.L.4
De Los Angeles, A.5
Mali, P.6
Aach, J.7
Kim-Kiselak, C.8
Briggs, A.W.9
Rios, X.10
-
16
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller,J.C., Tan,S., Qiao,G., Barlow,K.A., Wang,J., Xia,D.F., Meng,X., Paschon,D.E., Leung,E., Hinkley,S.J. et al. (2010) A TALE nuclease architecture for efficient genome editing. Nat. Biotechnol., 29, 143-148.
-
(2010)
Nat. Biotechnol.
, vol.29
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.2
Qiao, G.3
Barlow, K.A.4
Wang, J.5
Xia, D.F.6
Meng, X.7
Paschon, D.E.8
Leung, E.9
Hinkley, S.J.10
-
17
-
-
80052292973
-
High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases
-
Chen,F., Pruett-Miller,S.M., Huang,Y., Gjoka,M., Duda,K., Taunton,J., Collingwood,T.N., Frodin,M. and Davis,G.D. (2011) High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases. Nat. Methods, 8, 753-755.
-
(2011)
Nat. Methods
, vol.8
, pp. 753-755
-
-
Chen, F.1
Pruett-Miller, S.M.2
Huang, Y.3
Gjoka, M.4
Duda, K.5
Taunton, J.6
Collingwood, T.N.7
Frodin, M.8
Davis, G.D.9
-
18
-
-
84871519181
-
TALENs: A widely applicable technology for targeted genome editing
-
Joung,J.K. and Sander,J.D. (2012) TALENs: a widely applicable technology for targeted genome editing. Nat. Rev. Mol. Cell Biol., 14, 49-55.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 49-55
-
-
Joung, J.K.1
Sander, J.D.2
-
19
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali,P., Yang,L., Esvelt,K.M., Aach,J., Guell,M., DiCarlo,J.E., Norville,J.E. and Church,G.M. (2013) RNA-guided human genome engineering via Cas9. Science, 339, 823-826.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
20
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek,M., Chylinski,K., Fonfara,I., Hauer,M., Doudna,J.A. and Charpentier,E. (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science, 337, 816-821.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
21
-
-
0031863007
-
Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells
-
Donoho,G., Jasin,M. and Berg,P. (1998) Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Mol. Cell. Biol., 18, 4070-4078.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4070-4078
-
-
Donoho, G.1
Jasin, M.2
Berg, P.3
-
22
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong,L., Ran,F.A., Cox,D., Lin,S., Barretto,R., Habib,N., Hsu,P.D., Wu,X., Jiang,W., Marraffini,L.A. et al. (2013) Multiplex genome engineering using CRISPR/Cas systems. Science, 339, 819-823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
-
23
-
-
84872669342
-
In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration
-
Cristea,S., Freyvert,Y., Santiago,Y., Holmes,M.C., Urnov,F.D., Gregory,P.D. and Cost,G.J. (2013) In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration. Biotechnol. Bioeng., 110, 871-880.
-
(2013)
Biotechnol. Bioeng.
, vol.110
, pp. 871-880
-
-
Cristea, S.1
Freyvert, Y.2
Santiago, Y.3
Holmes, M.C.4
Urnov, F.D.5
Gregory, P.D.6
Cost, G.J.7
-
24
-
-
84874613680
-
Obligate ligation-gated recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining
-
Maresca,M., Lin,V.G., Guo,N. and Yang,Y. (2013) Obligate ligation-gated recombination (ObLiGaRe): custom-designed nuclease-mediated targeted integration through nonhomologous end joining. Genome Res., 23, 539-546.
-
(2013)
Genome Res.
, vol.23
, pp. 539-546
-
-
Maresca, M.1
Lin, V.G.2
Guo, N.3
Yang, Y.4
-
25
-
-
0030716796
-
Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase
-
Xia,S.J., Shammas,M.A. and Shmookler Reis,R.J. (1997) Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase. Mol. Cell. Biol., 17, 7151-7158.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 7151-7158
-
-
Xia, S.J.1
Shammas, M.A.2
Shmookler Reis, R.J.3
-
26
-
-
84875872895
-
Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase
-
Kass,E.M., Helgadottir,H.R., Chen,C.-C., Barbera,M., Wang,R., Westermark,U.K., Ludwig,T., Moynahan,M.E. and Jasin,M. (2013) Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase. Proc. Natl. Acad. Sci. U.S.A., 110, 5564-5569.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 5564-5569
-
-
Kass, E.M.1
Helgadottir, H.R.2
Chen, C.-C.3
Barbera, M.4
Wang, R.5
Westermark, U.K.6
Ludwig, T.7
Moynahan, M.E.8
Jasin, M.9
-
27
-
-
84925434302
-
CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes
-
Aach,J., Mali,P. and Church,G.M. (2014) CasFinder: flexible algorithm for identifying specific Cas9 targets in genomes. bioRxiv, doi:10.1101/005074.
-
(2014)
bioRxiv
-
-
Aach, J.1
Mali, P.2
Church, G.M.3
-
28
-
-
84898889321
-
CasOT: A genome-wide Cas9/gRNA off-target searching tool
-
Xiao,A., Cheng,Z., Kong,L., Zhu,Z., Lin,S., Gao,G. and Zhang,B. (2014) CasOT: a genome-wide Cas9/gRNA off-target searching tool. Bioinformatics, 30, 1180-1182.
-
(2014)
Bioinformatics
, vol.30
, pp. 1180-1182
-
-
Xiao, A.1
Cheng, Z.2
Kong, L.3
Zhu, Z.4
Lin, S.5
Gao, G.6
Zhang, B.7
-
29
-
-
77957755672
-
Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion
-
Sollu,C., Pars,K., Cornu,T.I., Thibodeau-Beganny,S., Maeder,M.L., Joung,J.K., Heilbronn,R. and Cathomen,T. (2010) Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion. Nucleic Acids Res., 38, 8269-8276.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 8269-8276
-
-
Sollu, C.1
Pars, K.2
Cornu, T.I.3
Thibodeau-Beganny, S.4
Maeder, M.L.5
Joung, J.K.6
Heilbronn, R.7
Cathomen, T.8
-
30
-
-
74949133880
-
Targeted chromosomal deletions in human cells using zinc finger nucleases
-
Lee,H.J., Kim,E. and Kim,J.-S. (2010) Targeted chromosomal deletions in human cells using zinc finger nucleases. Genome Res., 20, 81-89.
-
(2010)
Genome Res.
, vol.20
, pp. 81-89
-
-
Lee, H.J.1
Kim, E.2
Kim, J.-S.3
-
31
-
-
84885620722
-
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
-
Bauer,D.E., Kamran,S.C., Lessard,S., Xu,J., Fujiwara,Y., Lin,C., Shao,Z., Canver,M.C., Smith,E.C., Pinello,L. et al. (2013) An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science, 342, 253-257.
-
(2013)
Science
, vol.342
, pp. 253-257
-
-
Bauer, D.E.1
Kamran, S.C.2
Lessard, S.3
Xu, J.4
Fujiwara, Y.5
Lin, C.6
Shao, Z.7
Canver, M.C.8
Smith, E.C.9
Pinello, L.10
-
32
-
-
84884288934
-
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
-
Ran,F.A., Hsu,P.D., Lin,C.-Y., Gootenberg,J.S., Konermann,S., Trevino,A.E., Scott,D.A., Inoue,A., Matoba,S., Zhang,Y. et al. (2013) Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell, 154, 1380-1389.
-
(2013)
Cell
, vol.154
, pp. 1380-1389
-
-
Ran, F.A.1
Hsu, P.D.2
Lin, C.-Y.3
Gootenberg, J.S.4
Konermann, S.5
Trevino, A.E.6
Scott, D.A.7
Inoue, A.8
Matoba, S.9
Zhang, Y.10
-
33
-
-
84863275797
-
Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases
-
Lee,H.J., Kweon,J., Kim,E., Kim,S. and Kim,J.S. (2012) Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases. Genome Res., 22, 539-548.
-
(2012)
Genome Res.
, vol.22
, pp. 539-548
-
-
Lee, H.J.1
Kweon, J.2
Kim, E.3
Kim, S.4
Kim, J.S.5
-
34
-
-
84905388288
-
Characterization of genomic deletion efficiency mediated by CRISPR/Cas9 in mammalian cells
-
Canver,M.C., Bauer,D.E., Dass,A., Yien,Y.Y., Chung,J., Masuda,T., Maeda,T., Paw,B.H. and Orkin,S.H. (2014) Characterization of genomic deletion efficiency mediated by CRISPR/Cas9 in mammalian cells. J. Biol. Chem., doi:10.1074/jbc.M114.564625.
-
(2014)
J. Biol. Chem.
-
-
Canver, M.C.1
Bauer, D.E.2
Dass, A.3
Yien, Y.Y.4
Chung, J.5
Masuda, T.6
Maeda, T.7
Paw, B.H.8
Orkin, S.H.9
-
35
-
-
84880062591
-
Cancer translocations in human cells induced by zinc finger and TALE nucleases
-
Piganeau,M., Ghezraoui,H., De Cian,A., Guittat,L., Tomishima,M., Perrouault,L., Rene,O., Katibah,G.E., Zhang,L., Holmes,M.C. et al. (2013) Cancer translocations in human cells induced by zinc finger and TALE nucleases. Genome Res., 23, 1182-1193.
-
(2013)
Genome Res.
, vol.23
, pp. 1182-1193
-
-
Piganeau, M.1
Ghezraoui, H.2
De Cian, A.3
Guittat, L.4
Tomishima, M.5
Perrouault, L.6
Rene, O.7
Katibah, G.E.8
Zhang, L.9
Holmes, M.C.10
-
36
-
-
84901951241
-
Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system
-
Torres,R., Martin,M.C., Garcia,A., Cigudosa,J.C., Ramirez,J.C. and Rodriguez-Perales,S. (2014) Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system. Nat. Commun., 5, 3964.
-
(2014)
Nat. Commun.
, vol.5
, pp. 3964
-
-
Torres, R.1
Martin, M.C.2
Garcia, A.3
Cigudosa, J.C.4
Ramirez, J.C.5
Rodriguez-Perales, S.6
-
37
-
-
0029899891
-
Genetic manipulation of genomes with rare-cutting endonucleases
-
Jasin,M. (1996) Genetic manipulation of genomes with rare-cutting endonucleases. Trends Genet., 12, 224-228.
-
(1996)
Trends Genet.
, vol.12
, pp. 224-228
-
-
Jasin, M.1
-
38
-
-
0038523969
-
Chimeric nucleases stimulate gene targeting in human cells
-
Porteus,M.H. and Baltimore,D. (2003) Chimeric nucleases stimulate gene targeting in human cells. Science, 300, 763.
-
(2003)
Science
, vol.300
, pp. 763
-
-
Porteus, M.H.1
Baltimore, D.2
-
39
-
-
0037510038
-
Enhancing gene targeting with designed zinc finger nucleases
-
Bibikova,M., Beumer,K., Trautman,J.K. and Carroll,D. (2003) Enhancing gene targeting with designed zinc finger nucleases. Science, 300, 764.
-
(2003)
Science
, vol.300
, pp. 764
-
-
Bibikova, M.1
Beumer, K.2
Trautman, J.K.3
Carroll, D.4
-
40
-
-
80053539409
-
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
-
Song,L., Zhang,Z., Grasfeder,L.L., Boyle,A.P., Giresi,P.G., Lee,B.-K., Sheffield,N.C., Gra¨f,S., Huss,M., Keefe,D. et al. (2011) Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. Genome Res., 21, 1757-1767.
-
(2011)
Genome Res.
, vol.21
, pp. 1757-1767
-
-
Song, L.1
Zhang, Z.2
Grasfeder, L.L.3
Boyle, A.P.4
Giresi, P.G.5
Lee, B.-K.6
Sheffield, N.C.7
Gra¨f, S.8
Huss, M.9
Keefe, D.10
-
41
-
-
70349146995
-
Oligomerized pool engineering (OPEN): An 'open-source' protocol for making customized zinc-finger arrays
-
Maeder,M.L., Thibodeau-Beganny,S., Sander,J.D., Voytas,D.F. and Joung,J.K. (2009) Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays. Nat. Protoc., 4, 1471-1501.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1471-1501
-
-
Maeder, M.L.1
Thibodeau-Beganny, S.2
Sander, J.D.3
Voytas, D.F.4
Joung, J.K.5
-
42
-
-
84866879789
-
Iterative capped assembly: Rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
-
Briggs,A.W., Rios,X., Chari,R., Yang,L., Zhang,F., Mali,P. and Church,G.M. (2012) Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res., 40, e117.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. e117
-
-
Briggs, A.W.1
Rios, X.2
Chari, R.3
Yang, L.4
Zhang, F.5
Mali, P.6
Church, G.M.7
-
43
-
-
84864341757
-
A public resource facilitating clinical use of genomes
-
Ball,M.P., Thakuria,J.V., Zaranek,A.W., Clegg,T., Rosenbaum,A.M., Wu,X., Angrist,M., Bhak,J., Bobe,J., Callow,M.J. et al. (2012) A public resource facilitating clinical use of genomes. Proc. Natl. Acad. Sci. U.S.A., 109, 11920-11927.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 11920-11927
-
-
Ball, M.P.1
Thakuria, J.V.2
Zaranek, A.W.3
Clegg, T.4
Rosenbaum, A.M.5
Wu, X.6
Angrist, M.7
Bhak, J.8
Bobe, J.9
Callow, M.J.10
-
44
-
-
73649113113
-
A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells
-
Lee,J.-H., Park,I.-H., Gao,Y., Li,J.B., Li,Z., Daley,G.Q., Zhang,K. and Church,G.M. (2009) A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells. PLoS Genet., 5, e1000718.
-
(2009)
PLoS Genet.
, vol.5
-
-
Lee, J.-H.1
Park, I.-H.2
Gao, Y.3
Li, J.B.4
Li, Z.5
Daley, G.Q.6
Zhang, K.7
Church, G.M.8
-
45
-
-
43149086004
-
Derivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryos
-
Lerou,P.H., Yabuuchi,A., Huo,H., Miller,J.D., Boyer,L.F., Schlaeger,T.M. and Daley,G.Q. (2008) Derivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryos. Nat. Protoc., 3, 923-933.
-
(2008)
Nat. Protoc.
, vol.3
, pp. 923-933
-
-
Lerou, P.H.1
Yabuuchi, A.2
Huo, H.3
Miller, J.D.4
Boyer, L.F.5
Schlaeger, T.M.6
Daley, G.Q.7
-
46
-
-
84867002724
-
A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs
-
Valamehr,B., Abujarour,R., Robinson,M., Le,T., Robbins,D., Shoemaker,D. and Flynn,P. (2012) A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs. Sci. Rep., 2, 213-213.
-
(2012)
Sci. Rep.
, vol.2
, pp. 213-213
-
-
Valamehr, B.1
Abujarour, R.2
Robinson, M.3
Le, T.4
Robbins, D.5
Shoemaker, D.6
Flynn, P.7
-
47
-
-
0026598614
-
Genomic DNA microextraction: A method to screen numerous samples
-
Ramírez-Solis,R., Rivera-Pérez,J., Wallace,J.D., Wims,M., Zheng,H. and Bradley,A. (1992) Genomic DNA microextraction: a method to screen numerous samples. Anal. Biochem., 201, 331-335.
-
(1992)
Anal. Biochem.
, vol.201
, pp. 331-335
-
-
Ramírez-Solis, R.1
Rivera-Pérez, J.2
Wallace, J.D.3
Wims, M.4
Zheng, H.5
Bradley, A.6
-
48
-
-
48249149566
-
Decoding of superimposed traces produced by direct sequencing of heterozygous indels
-
Dmitriev,D.A. and Rakitov,R.A. (2008) Decoding of superimposed traces produced by direct sequencing of heterozygous indels. PLoS Comput. Biol., 4, e1000113.
-
(2008)
PLoS Comput. Biol.
, vol.4
-
-
Dmitriev, D.A.1
Rakitov, R.A.2
-
49
-
-
84913592416
-
Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA)
-
Guell,M., Yang,L. and Church,G.M. Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA). Bioinformatics, 30, 2968-2970.
-
Bioinformatics
, vol.30
, pp. 2968-2970
-
-
Guell, M.1
Yang, L.2
Church, G.M.3
-
50
-
-
0036244901
-
Surface antigens of human embryonic stem cells: Changes upon differentiation in culture
-
Draper,J.S., Pigott,C., Thomson,J.A. and Andrews,P.W. (2002) Surface antigens of human embryonic stem cells: changes upon differentiation in culture. J. Anat., 200, 249-258.
-
(2002)
J. Anat.
, vol.200
, pp. 249-258
-
-
Draper, J.S.1
Pigott, C.2
Thomson, J.A.3
Andrews, P.W.4
-
51
-
-
0023684936
-
Dependence of intrachromosomal recombination in mammalian cells on uninterrupted homology
-
Waldman,A.S. and Liskay,R.M. (1988) Dependence of intrachromosomal recombination in mammalian cells on uninterrupted homology. Mol. Cell. Biol., 8, 5350-5357.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 5350-5357
-
-
Waldman, A.S.1
Liskay, R.M.2
-
52
-
-
0022369587
-
The human Thy-1 gene: Structure and chromosomal location
-
Seki,T., Spurr,N., Obata,F., Goyert,S., Goodfellow,P. and Silver,J. (1985) The human Thy-1 gene: structure and chromosomal location. Proc. Natl. Acad. Sci. U.S.A., 82, 6657-6661.
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 6657-6661
-
-
Seki, T.1
Spurr, N.2
Obata, F.3
Goyert, S.4
Goodfellow, P.5
Silver, J.6
-
53
-
-
0037382904
-
Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes
-
Yang,Y. and Seed,B. (2003) Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes. Nat. Biotechnol., 21, 447-451.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 447-451
-
-
Yang, Y.1
Seed, B.2
-
54
-
-
0038023191
-
High-throughput engineering of the mouse genome coupled with high-resolution expression analysis
-
Valenzuela,D.M., Murphy,A.J., Frendewey,D., Gale,N.W., Economides,A.N., Auerbach,W., Poueymirou,W.T., Adams,N.C., Rojas,J., Yasenchak,J. et al. (2003) High-throughput engineering of the mouse genome coupled with high-resolution expression analysis. Nat. Biotechnol., 21, 652-659.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 652-659
-
-
Valenzuela, D.M.1
Murphy, A.J.2
Frendewey, D.3
Gale, N.W.4
Economides, A.N.5
Auerbach, W.6
Poueymirou, W.T.7
Adams, N.C.8
Rojas, J.9
Yasenchak, J.10
-
55
-
-
84878226536
-
Origins and implications of pluripotent stem cell variability and heterogeneity
-
Cahan,P. and Daley,G.Q. (2013) Origins and implications of pluripotent stem cell variability and heterogeneity. Nat. Rev. Mol. Cell Biol., 14, 357-368.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 357-368
-
-
Cahan, P.1
Daley, G.Q.2
-
56
-
-
84892749369
-
Genetic screens in human cells using the CRISPR-Cas9 system
-
Wang,T., Wei,J.J., Sabatini,D.M. and Lander,E.S. (2014) Genetic screens in human cells using the CRISPR-Cas9 system. Science, 343, 80-84.
-
(2014)
Science
, vol.343
, pp. 80-84
-
-
Wang, T.1
Wei, J.J.2
Sabatini, D.M.3
Lander, E.S.4
-
57
-
-
84865364870
-
Playing the end game: DNA double-strand break repair pathway choice
-
Chapman,J.R., Taylor,M.R.G. and Boulton,S.J. (2012) Playing the end game: DNA double-strand break repair pathway choice. Mol. Cell, 47, 497-510.
-
(2012)
Mol. Cell
, vol.47
, pp. 497-510
-
-
Chapman, J.R.1
Taylor, M.R.G.2
Boulton, S.J.3
-
58
-
-
78149425175
-
Regulation of homologous recombination in eukaryotes
-
Heyer,W.-D., Ehmsen,K.T. and Liu,J. (2010) Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet., 44, 113-139.
-
(2010)
Annu. Rev. Genet.
, vol.44
, pp. 113-139
-
-
Heyer, W.-D.1
Ehmsen, K.T.2
Liu, J.3
-
59
-
-
77950656734
-
Mechanisms of recombination between diverged sequences in wild-type and BLM-deficient mouse and human cells
-
LaRocque,J.R. and Jasin,M. (2010) Mechanisms of recombination between diverged sequences in wild-type and BLM-deficient mouse and human cells. Mol. Cell. Biol., 30, 1887-1897.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1887-1897
-
-
LaRocque, J.R.1
Jasin, M.2
-
60
-
-
84901291667
-
The mechanism of gene targeting in human somatic cells
-
Kan,Y., Ruis,B., Lin,S. and Hendrickson,E.A. (2014) The mechanism of gene targeting in human somatic cells. PLoS Genet., 10, e1004251.
-
(2014)
PLoS Genet.
, vol.10
-
-
Kan, Y.1
Ruis, B.2
Lin, S.3
Hendrickson, E.A.4
-
61
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
-
Fu,Y., Foden,J.A., Khayter,C., Maeder,M.L., Reyon,D., Joung,J.K. and Sander,J.D. (2013) High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol., 31, 822-826.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 822-826
-
-
Fu, Y.1
Foden, J.A.2
Khayter, C.3
Maeder, M.L.4
Reyon, D.5
Joung, J.K.6
Sander, J.D.7
-
62
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu,P.D., Scott,D.A., Weinstein,J.A., Ran,F.A., Konermann,S., Agarwala,V., Li,Y., Fine,E.J., Wu,X., Shalem,O. et al. (2013) DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol., 31, 827-832.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
Scott, D.A.2
Weinstein, J.A.3
Ran, F.A.4
Konermann, S.5
Agarwala, V.6
Li, Y.7
Fine, E.J.8
Wu, X.9
Shalem, O.10
-
63
-
-
84884155038
-
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
-
Pattanayak,V., Lin,S., Guilinger,J.P., Ma,E., Doudna,J.A. and Liu,D.R. (2013) High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat. Biotechnol., 31, 839-843.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 839-843
-
-
Pattanayak, V.1
Lin, S.2
Guilinger, J.P.3
Ma, E.4
Doudna, J.A.5
Liu, D.R.6
-
64
-
-
84903545084
-
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
-
Kuscu,C., Arslan,S., Singh,R., Thorpe,J. and Adli,M. (2014) Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease. Nat. Biotechnol., 32, 677-683.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 677-683
-
-
Kuscu, C.1
Arslan, S.2
Singh, R.3
Thorpe, J.4
Adli, M.5
-
65
-
-
84902095352
-
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
-
Wu,X., Scott,D.A., Kriz,A.J., Chiu,A.C., Hsu,P.D., Dadon,D.B., Cheng,A.W., Trevino,A.E., Konermann,S., Chen,S. et al. (2014) Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nat. Biotechnol., 32, 670-676.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 670-676
-
-
Wu, X.1
Scott, D.A.2
Kriz, A.J.3
Chiu, A.C.4
Hsu, P.D.5
Dadon, D.B.6
Cheng, A.W.7
Trevino, A.E.8
Konermann, S.9
Chen, S.10
-
66
-
-
84884160273
-
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
-
Mali,P., Aach,J., Stranges,P.B., Esvelt,K.M., Moosburner,M., Kosuri,S., Yang,L. and Church,G.M. (2013) CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat. Biotechnol., 31, 833-838.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 833-838
-
-
Mali, P.1
Aach, J.2
Stranges, P.B.3
Esvelt, K.M.4
Moosburner, M.5
Kosuri, S.6
Yang, L.7
Church, G.M.8
-
67
-
-
84896717088
-
Is non-homologous end-joining really an inherently error-prone process?
-
Bétermier,M., Bertrand,P. and Lopez,B.S. (2014) Is non-homologous end-joining really an inherently error-prone process? PLoS Genet., 10, e1004086.
-
(2014)
PLoS Genet.
, vol.10
-
-
Bétermier, M.1
Bertrand, P.2
Lopez, B.S.3
|