Efficient gene editing in adult mouse livers via adenoviral delivery of CRISPR/Cas9

FEBS Letters

Volumn 588, Issue 21, 2014, Pages 3954-3958

  Cheng, Ranran ^a,b   Peng, Jin ^a,c   Yan, Yonghong ^a   Cao, Peili ^a   Wang, Jiewei ^a,d   Qiu, Chen ^a   Tang, Lichun ^a   Liu, Di ^a   Tang, Li ^a   Jin, Jianping ^e   Huang, Xingxu ^f   He, Fuchu ^a,g   Zhang, Pumin ^a,g,h  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b BEIJING UNIVERSITY OF TECHNOLOGY   (China)

^c EAST CHINA NORMAL UNIVERSITY   (China)

^d ZHEJIANG UNIVERSITY   (China)

^e UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^f NANJING UNIVERSITY   (China)

^g BEIJING INSTITUTE OF LIFEOMICS   (China)

^h BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Adenoviruses; CRISPR Cas9; Gene editing; Liver

Indexed keywords

GENOMIC DNA; MESSENGER RNA; VIRUS VECTOR;

ADENOVIRUS; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; GENE EDITING; GENOME ANALYSIS; HOST CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEIC ACID STRUCTURE, METABOLISM AND FUNCTION; PHENOTYPE; POLYMERASE CHAIN REACTION; PROCESS DEVELOPMENT; SEQUENCE ANALYSIS; SPECTROSCOPY; VIRAL GENE DELIVERY SYSTEM; VIRUS GENOME; VIRUS IDENTIFICATION; ADENOVIRIDAE; ANIMAL; GENE TARGETING; GENETICS; HUMAN; LIVER; METABOLISM; NUCLEOTIDE SEQUENCE; PROCEDURES;

ADENOVIRIDAE; ANIMALS; BASE SEQUENCE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; GENE TARGETING; HUMANS; LIVER; MALE; MICE;

EID: 84908245956     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.09.008     Document Type: Article

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