CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos

Nature Protocols

Volumn 9, Issue 10, 2014, Pages 2493-2512

  Shao, Yanjiao ^a   Guan, Yuting ^a   Wang, Liren ^a   Qiu, Zhongwei ^a   Liu, Meizhen ^a   Chen, Yuting ^a   Wu, Lijuan ^a   Li, Yongmei ^a   Ma, Xueyun ^a   Liu, Mingyao ^a,b   Li, Dali ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; EMBRYO; FEMALE; GENE INACTIVATION; GENE INSERTION; GENE MUTATION; GENE SYNTHESIS; GENE TARGETING; GENOME EDITING; HOMOLOGOUS RECOMBINATION; KNOCKOUT RAT; MALE; MICROINJECTION; NONHUMAN; PRIORITY JOURNAL; PROGENY; RAT; RNA EDITING; ANIMAL; ANIMAL EMBRYO; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CYTOLOGY; DEVICES; GENOME; MUTATION; PROCEDURES; SPRAGUE DAWLEY RAT; TRANSGENIC RAT;

ANIMALIA; RATTUS;

ANIMALS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; EMBRYO, MAMMALIAN; GENE KNOCK-IN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; GENE TARGETING; GENOME; HOMOLOGOUS RECOMBINATION; MICROINJECTIONS; MUTATION; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC;

EID: 84923779856     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2014.171     Document Type: Article

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