-
1
-
-
33645765312
-
Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
-
Rolo, A. P.; Palmeira, C. M. Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol. Appl. Pharmacol., 2006, 212, 167-178
-
(2006)
Toxicol. Appl. Pharmacol
, vol.212
, pp. 167-178
-
-
Rolo, A.P.1
Palmeira, C.M.2
-
2
-
-
77449139468
-
PGC-1alpha activation as a therapeutic approach in mitochondrial disease
-
Wenz, T. PGC-1alpha activation as a therapeutic approach in mitochondrial disease. IUBMB Life, 2009, 61, 1051-1062
-
(2009)
IUBMB Life
, vol.61
, pp. 1051-1062
-
-
Wenz, T.1
-
3
-
-
77949882290
-
Mitochondrial energetics and therapeutics
-
Wallace, D. C.; Fan, W.; Procaccio, V. Mitochondrial energetics and therapeutics. Annu. Rev. Pathol., 2010, 5, 297-348
-
(2010)
Annu. Rev. Pathol
, vol.5
, pp. 297-348
-
-
Wallace, D.C.1
Fan, W.2
Procaccio, V.3
-
4
-
-
79955575803
-
Regulation of mitochondrial biogenesis in metabolic syndrome
-
Rolo, A. P.; Gomes, A. P.; Palmeira, C. M. Regulation of mitochondrial biogenesis in metabolic syndrome. Curr. Drug Targets, 2011, 12, 872-878
-
(2011)
Curr. Drug Targets
, vol.12
, pp. 872-878
-
-
Rolo, A.P.1
Gomes, A.P.2
Palmeira, C.M.3
-
5
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley, D. E.; He, J.; Menshikova, E. V.; Ritov, V. B. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes, 2002, 51, 2944-2950
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
6
-
-
0038054341
-
PGC-1alpharesponsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha, V. K.; Lindgren, C. M.; Eriksson, K. F.; Subramanian, A.; Sihag, S.; Lehar, J.; Puigserver, P.; Carlsson, E.; Ridderstrale, M.; Laurila, E.; Houstis, N.; Daly, M. J.; Patterson, N.; Mesirov, J. P.; Golub, T. R.; Tamayo, P.; Spiegelman, B.; Lander, E. S.; Hirschhorn, J. N.; Altshuler, D.; Groop, L. C. PGC-1alpharesponsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet., 2003, 34, 267-273
-
(2003)
Nat. Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
Houstis, N.11
Daly, M.J.12
Patterson, N.13
Mesirov, J.P.14
Golub, T.R.15
Tamayo, P.16
Spiegelman, B.17
Lander, E.S.18
Hirschhorn, J.N.19
Altshuler, D.20
Groop, L.C.21
more..
-
7
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti, M. E.; Butte, A. J.; Crunkhorn, S.; Cusi, K.; Berria, R.; Kashyap, S.; Miyazaki, Y.; Kohane, I.; Costello, M.; Saccone, R.; Landaker, E. J.; Goldfine, A. B.; Mun, E.; DeFronzo, R.; Finlayson, J.; Kahn, C. R.; Mandarino, L. J. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1. Proc. Natl. Acad. Sci. U.S.A., 2003, 100, 8466-8471
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
Landaker, E.J.11
Goldfine, A.B.12
Mun, E.13
Defronzo, R.14
Finlayson, J.15
Kahn, C.R.16
Mandarino, L.J.17
-
8
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell, B. B.; Shulman, G. I. Mitochondrial dysfunction and type 2 diabetes. Science, 2005, 307, 384-387
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
9
-
-
34447511610
-
Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: Potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation
-
Crunkhorn, S.; Dearie, F.; Mantzoros, C.; Gami, H.; da Silva, W. S.; Espinoza, D.; Faucette, R.; Barry, K.; Bianco, A. C.; Patti, M. E. Peroxisome proliferator activator receptor gamma coactivator-1 expression Is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. J. Biol. Chem., 2007, 282, 15439-15450
-
(2007)
J. Biol. Chem
, vol.282
, pp. 15439-15450
-
-
Crunkhorn, S.1
Dearie, F.2
Mantzoros, C.3
Gami, H.4
Da Silva, W.S.5
Espinoza, D.6
Faucette, R.7
Barry, K.8
Bianco, A.C.9
Patti, M.E.10
-
10
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves, T. R.; Ussher, J. R.; Noland, R. C.; Slentz, D.; Mosedale, M.; Ilkayeva, O.; Bain, J.; Stevens, R.; Dyck, J. R. B.; Newgard, C. B.; Lopaschuk, G. D.; Muoio, D. M. Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab., 2008, 7, 45-56
-
(2008)
Cell Metab
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
Slentz, D.4
Mosedale, M.5
Ilkayeva, O.6
Bain, J.7
Stevens, R.8
Dyck, J.R.B.9
Newgard, C.B.10
Lopaschuk, G.D.11
Muoio, D.M.12
-
11
-
-
64249152819
-
Aging impairs skeletal muscle mitochondrial bioenergetic function
-
Figueiredo, P. A.; Powers, S. K.; Ferreira, R. M.; Appell, H. J.; Duarte, J. A. Aging impairs skeletal muscle mitochondrial bioenergetic function. J. Gerontol. A. Biol. Sci. Med. Sci., 2009, 64, 21-33
-
(2009)
J. Gerontol. A. Biol. Sci. Med. Sci
, vol.64
, pp. 21-33
-
-
Figueiredo, P.A.1
Powers, S.K.2
Ferreira, R.M.3
Appell, H.J.4
Duarte, J.A.5
-
12
-
-
0015140966
-
Age differences in the ultrastructure of axons in the pyramidal tract of the mouse
-
Samorajski, T.; Friede, R. L.; Ordy, J. M. Age differences in the ultrastructure of axons in the pyramidal tract of the mouse. J. Gerontol., 1971, 26, 542-551
-
(1971)
J. Gerontol
, vol.26
, pp. 542-551
-
-
Samorajski, T.1
Friede, R.L.2
Ordy, J.M.3
-
13
-
-
0017233986
-
A morphometric study of the density of mitochondrial cristae in heart and liver of aging mice
-
Tate, E. L.; Herbener, G. H. A morphometric study of the density of mitochondrial cristae in heart and liver of aging mice. J. Gerontol., 1976, 31, 129-134
-
(1976)
J. Gerontol.
, vol.31
, pp. 129-134
-
-
Tate, E.L.1
Herbener, G.H.2
-
14
-
-
2342525090
-
Mitochondrial DNA mutation and depletion increase the susceptibility of human cells to apoptosis
-
Liu, C. Y.; Lee, C. F.; Hong, C. H.; Wei, Y. H. Mitochondrial DNA mutation and depletion increase the susceptibility of human cells to apoptosis. Ann. N. Y. Acad. Sci., 2004, 1011, 133-145
-
(2004)
Ann. N. Y. Acad. Sci
, vol.1011
, pp. 133-145
-
-
Liu, C.Y.1
Lee, C.F.2
Hong, C.H.3
Wei, Y.H.4
-
15
-
-
34548634634
-
Transcriptional response to aging and caloric restriction in heart and adipose tissue
-
Linford, N. J.; Beyer, R. P.; Gollahon, K.; Krajcik, R. A.; Malloy, V. L.; Demas, V.; Burmer, G. C.; Rabinovitch, P. S. Transcriptional response to aging and caloric restriction in heart and adipose tissue. Aging Cell, 2007, 6, 673-688
-
(2007)
Aging Cell
, vol.6
, pp. 673-688
-
-
Linford, N.J.1
Beyer, R.P.2
Gollahon, K.3
Krajcik, R.A.4
Malloy, V.L.5
Demas, V.6
Burmer, G.C.7
Rabinovitch, P.S.8
-
16
-
-
35348971990
-
Resistance exercise reverses aging in human skeletal muscle
-
Melov, S.; Tarnopolsky, M. A.; Beckman, K.; Felkey, K.; Hubbard, A. Resistance exercise reverses aging in human skeletal muscle. PLoS One, 2007, 2, e465
-
(2007)
PLoS One
, vol.2
, pp. e465
-
-
Melov, S.1
Tarnopolsky, M.A.2
Beckman, K.3
Felkey, K.4
Hubbard, A.5
-
17
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth, G. C.; Hiona, A.; Pugh, T. D.; Someya, S.; Panzer, K.; Wohlgemuth, S. E.; Hofer, T.; Seo, A. Y.; Sullivan, R.; Jobling, W. A.; Morrow, J. D.; Van Remmen, H.; Sedivy, J. M.; Yamasoba, T.; Tanokura, M.; Weindruch, R.; Leeuwenburgh, C.; Prolla, T. A. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science, 2005, 309, 481-484
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
Morrow, J.D.11
Van Remmen, H.12
Sedivy, J.M.13
Yamasoba, T.14
Tanokura, M.15
Weindruch, R.16
Leeuwenburgh, C.17
Prolla, T.A.18
-
18
-
-
84900534961
-
The biochemistry and cell biology of aging: Metabolic regulation through mitochondrial signaling
-
Long, Y. C.; Tan, T. M. C.; Takao, I.; Tang, B. L. The biochemistry and cell biology of aging: metabolic regulation through mitochondrial signaling. Am. J. Physiol. Endocrinol. Metab., 2014, 306, E581-E591
-
(2014)
Am. J. Physiol. Endocrinol. Metab
, vol.306
, pp. E581-E591
-
-
Long, Y.C.1
Tan, T.M.C.2
Takao, I.3
Tang, B.L.4
-
19
-
-
42049114034
-
Transcriptional paradigms in mammalian mitochondrial biogenesis and function
-
Scarpulla, R. C. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol. Rev., 2008, 88, 611-638
-
(2008)
Physiol. Rev
, vol.88
, pp. 611-638
-
-
Scarpulla, R.C.1
-
20
-
-
84864314311
-
Nucleus-encoded regulators of mitochondrial function: Integration of respiratory chainexpression, nutrient sensing and metabolic stress
-
Scarpulla, R. C. Nucleus-encoded regulators of mitochondrial function: integration of respiratory chainexpression, nutrient sensing and metabolic stress. Biochim. Biophys. Acta, 2011, 1819, 1088-1097
-
(2011)
Biochim. Biophys. Acta
, vol.1819
, pp. 1088-1097
-
-
Scarpulla, R.C.1
-
21
-
-
84907528499
-
The role of microRNAs in mitochondria: Small players acting wide
-
Duarte, F. V.; Palmeira, C. M.; Rolo, A. P. The role of microRNAs in mitochondria: small players acting wide. Genes, 2014, 5, 865-886
-
(2014)
Genes
, vol.5
, pp. 865-886
-
-
Duarte, F.V.1
Palmeira, C.M.2
Rolo, A.P.3
-
22
-
-
84893855759
-
Mitochondrial stress signaling promotes cellular adaptations
-
Barbour, J. A.; Turner, N. Mitochondrial stress signaling promotes cellular adaptations. Int. J. Cell Biol., 2014, 2014, 156020
-
(2014)
Int. J. Cell Biol
, vol.2014
, pp. 156020
-
-
Barbour, J.A.1
Turner, N.2
-
23
-
-
77955861146
-
Autophagy in health and disease.5. Mitophagy as a way of life
-
Gottlieb, R. A.; Carreira, R. S. Autophagy in health and disease. 5. mitophagy as a way of life. Am. J. Physiol. Cell Physiol., 2010, 299, C203-C210
-
(2010)
Am. J. Physiol. Cell Physiol
, vol.299
, pp. C203-C210
-
-
Gottlieb, R.A.1
Carreira, R.S.2
-
24
-
-
84923685347
-
Mitochondria: From cell death executioners to regulators of cell differentiation
-
Kasahara, A.; Scorrano, L. Mitochondria: from cell death executioners to regulators of cell differentiation. Trends Cell Biol., 2014, 24, 761-770
-
(2014)
Trends Cell Biol
, vol.24
, pp. 761-770
-
-
Kasahara, A.1
Scorrano, L.2
-
25
-
-
70350324917
-
Mitochondrial "kiss-and-run": Interplay between mitochondrial motility and fusion-fission dynamics
-
Liu, X.; Weaver, D.; Shirihai, O.; Hajnoczky, G. Mitochondrial "kiss-and-run": interplay between mitochondrial motility and fusion-fission dynamics. EMBO J., 2009, 28, 3074-3089
-
(2009)
EMBO J
, vol.28
, pp. 3074-3089
-
-
Liu, X.1
Weaver, D.2
Shirihai, O.3
Hajnoczky, G.4
-
26
-
-
84857034651
-
Less than perfect divorces: Dysregulated mitochondrial fission and neurodegeneration
-
Oettinghaus, B.; Licci, M.; Scorrano, L.; Frank, S. Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration. Acta Neuropathol., 2012, 123, 189-203
-
(2012)
Acta Neuropathol
, vol.123
, pp. 189-203
-
-
Oettinghaus, B.1
Licci, M.2
Scorrano, L.3
Frank, S.4
-
27
-
-
77957798188
-
A Lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division
-
Chang, C.-R.; Manlandro, C. M.; Arnoult, D.; Stadler, J.; Posey, A. E.; Hill, R. B.; Blackstone, C. A Lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division. J. Biol. Chem., 2010, 285, 32494-32503
-
(2010)
J.Biol.Chem
, vol.285
, pp. 32494-32503
-
-
Chang, C.-R.1
Manlandro, C.M.2
Arnoult, D.3
Stadler, J.4
Posey, A.E.5
Hill, R.B.6
Blackstone, C.7
-
28
-
-
24144462451
-
Expression of Mfn2, the charcot-marie-tooth neuropathy type 2A gene, in human skeletal muscle: Effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6
-
Bach, D.; Naon, D.; Pich, S.; Soriano, F. X.; Vega, N.; Rieusset, J.; Laville, M.; Guillet, C.; Boirie, Y.; Wallberg-Henriksson, H.; Manco, M.; Calvani, M.; Castagneto, M.; Palacin, M.; Mingrone, G.; Zierath, J. R.; Vidal, H.; Zorzano, A. Expression of Mfn2, the charcot-marie-tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6. Diabetes, 2005, 54, 2685-2693
-
(2005)
Diabetes
, vol.54
, pp. 2685-2693
-
-
Bach, D.1
Naon, D.2
Pich, S.3
Soriano, F.X.4
Vega, N.5
Rieusset, J.6
Laville, M.7
Guillet, C.8
Boirie, Y.9
Wallberg-Henriksson, H.10
Manco, M.11
Calvani, M.12
Castagneto, M.13
Palacin, M.14
Mingrone, G.15
Zierath, J.R.16
Vidal, H.17
Zorzano, A.18
-
29
-
-
33747702159
-
Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women
-
Toledo, F. G. S.; Watkins, S.; Kelley, D. E. Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women. J. Clin. Endocrinol. Metab., 2006, 91, 3224-3227
-
(2006)
J. Clin. Endocrinol. Metab
, vol.91
, pp. 3224-3227
-
-
Toledo, F.G.S.1
Watkins, S.2
Kelley, D.E.3
-
30
-
-
0037593949
-
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism: A novel regulatory mechanism altered in obesity
-
Bach, D.; Pich, S.; Soriano, F. X.; Vega, N.; Baumgartner, B.; Oriola, J.; Daugaard, J. R.; Lloberas, J.; Camps, M.; Zierath, J. R.; Rabasa-Lhoret, R.; Wallberg-Henriksson, H.; Laville, M.; Palacin, M.; Vidal, H.; Rivera, F.; Brand, M.; Zorzano, A. Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism: a novel regulatory mechanism altered in obesity. J. Biol. Chem., 2003, 278, 17190-17197
-
(2003)
J. Biol. Chem
, vol.278
, pp. 17190-17197
-
-
Bach, D.1
Pich, S.2
Soriano, F.X.3
Vega, N.4
Baumgartner, B.5
Oriola, J.6
Daugaard, J.R.7
Lloberas, J.8
Camps, M.9
Zierath, J.R.10
Rabasa-Lhoret, R.11
Wallberg-Henriksson, H.12
Laville, M.13
Palacin, M.14
Vidal, H.15
Rivera, F.16
Brand, M.17
Zorzano, A.18
-
31
-
-
13444306450
-
Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators
-
Gleyzer, N.; Vercauteren, K.; Scarpulla, R. C. Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators. Mol. Cell. Biol., 2005, 25, 1354-1366
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 1354-1366
-
-
Gleyzer, N.1
Vercauteren, K.2
Scarpulla, R.C.3
-
32
-
-
0037102256
-
Transcriptional coactivator PGC-1 a drives the formation of slow-twitch muscle fibres
-
Lin, J.; Wu, H.; Tarr, P. T.; Zhang, C.; Wu, Z. Transcriptional coactivator PGC-1 a drives the formation of slow-twitch muscle fibres. Nature, 2002, 418, 797-801
-
(2002)
Nature
, vol.418
, pp. 797-801
-
-
Lin, J.1
Wu, H.2
Tarr, P.T.3
Zhang, C.4
Wu, Z.5
-
33
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver, P.; Wu, Z.; Park, C. W.; Graves, R.; Wright, M.; Spiegelma, B. M. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell, 1999, 92, 829-839
-
(1999)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelma, B.M.6
-
34
-
-
0037322888
-
Exercise induces transient transcriptional activation of the PGC-1 gene in human skeletal muscle
-
Pilegaard, H.; Saltin, B.; Neufer, P. D. Exercise induces transient transcriptional activation of the PGC-1 gene in human skeletal muscle. J. Physiol., 2003, 546, 851-858
-
(2003)
J. Physiol
, vol.546
, pp. 851-858
-
-
Pilegaard, H.1
Saltin, B.2
Neufer, P.D.3
-
35
-
-
0037251709
-
Regulation of mitochondrial biogenesis by thyroid hormone
-
Weitzel, J. M.; Iwen, K. A. H.; Seitz, H. J. Regulation of mitochondrial biogenesis by thyroid hormone. Exp. Physiol., 2003, 88, 121-128
-
(2003)
Exp. Physiol
, vol.88
, pp. 121-128
-
-
Weitzel, J.M.1
Iwen, K.A.H.2
Seitz, H.J.3
-
36
-
-
0037134493
-
The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha
-
Kressler, D.; Schreiber, S. N.; Knutti, D.; Kralli, A. The PGC-1-related protein PERC Is a selective coactivator of estrogen receptor alpha. J. Biol. Chem., 2002, 277, 13918-13925
-
(2002)
J. Biol. Chem
, vol.277
, pp. 13918-13925
-
-
Kressler, D.1
Schreiber, S.N.2
Knutti, D.3
Kralli, A.4
-
37
-
-
0035016566
-
Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
-
Andersson, U.; Scarpulla, R. C. Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol. Cell. Biol., 2001, 21, 3738-3749
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 3738-3749
-
-
Andersson, U.1
Scarpulla, R.C.2
-
38
-
-
47549114849
-
Transcriptional coactivators PGC-1alpha and PGC-Lbeta control overlapping programs required for erinatal maturation of the heart
-
Lai, L.; Leone, T. C.; Zechner, C.; Schaeffer, P. J.; Kelly, S. M.; Flanagan, D. P.; Medeiros, D. M.; Kovacs, A.; Kelly, D. P. Transcriptional coactivators PGC-1alpha and PGC-Lbeta control overlapping programs required for erinatal maturation of the heart. Genes Dev., 2008, 22, 1948-1961
-
(2008)
Genes Dev
, vol.22
, pp. 1948-1961
-
-
Lai, L.1
Leone, T.C.2
Zechner, C.3
Schaeffer, P.J.4
Kelly, S.M.5
Flanagan, D.P.6
Medeiros, D.M.7
Kovacs, A.8
Kelly, D.P.9
-
39
-
-
78649508058
-
Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
-
Zechner, C.; Lai, L.; Zechner, J. F.; Geng, T.; Yan, Z.; Rumsey, J. W.; Collia, D.; Chen, Z.; Wozniak, D. F.; Leone, T. C.; Kelly, D. P. Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity. Cell Metab., 2010, 12, 633-642
-
(2010)
Cell Metab
, vol.12
, pp. 633-642
-
-
Zechner, C.1
Lai, L.2
Zechner, J.F.3
Geng, T.4
Yan, Z.5
Rumsey, J.W.6
Collia, D.7
Chen, Z.8
Wozniak, D.F.9
Leone, T.C.10
Kelly, D.P.11
-
40
-
-
0034751958
-
Effect of short-term caloric restriction on H2O2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source
-
Gredilla, R.; Barja, G.; Lopez-Torres, M. Effect of short-term caloric restriction on H2O2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source. J. Bioenerg. Biomembr., 2001, 33, 279-287
-
(2001)
J. Bioenerg. Biomembr
, vol.33
, pp. 279-287
-
-
Gredilla, R.1
Barja, G.2
Lopez-Torres, M.3
-
41
-
-
20044384556
-
Dietary restriction at old age lowers mitochondrial oxygen radical production and leak at complex i and oxidative DNA damage in rat brain
-
Sanz, A.; Caro, P.; Ibanez, J.; Gomez, J.; Gredilla, R.; Barja, G. Dietary restriction at old age lowers mitochondrial oxygen radical production and leak at complex I and oxidative DNA damage in rat brain. J. Bioenerg. Biomembr., 2005, 37, 83-90
-
(2005)
J. Bioenerg. Biomembr
, vol.37
, pp. 83-90
-
-
Sanz, A.1
Caro, P.2
Ibanez, J.3
Gomez, J.4
Gredilla, R.5
Barja, G.6
-
42
-
-
32444437067
-
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
-
Lopez-Lluch, G.; Hunt, N.; Jones, B.; Zhu, M.; Jamieson, H.; Hilmer, S.; Cascajo, M. V; Allard, J.; Ingram, D. K.; Navas, P.; de Cabo, R. Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc. Natl. Acad. Sci. U.S.A., 2006, 103, 1768-1773
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 1768-1773
-
-
Lopez-Lluch, G.1
Hunt, N.2
Jones, B.3
Zhu, M.4
Jamieson, H.5
Hilmer, S.6
Cascajo, M.V.7
Allard, J.8
Ingram, D.K.9
Navas, P.10
De Cabo, R.11
-
43
-
-
85047691371
-
Multiple environmental and genetic factors influence skeletal muscle PGC-1 and PGC-1 gene expression in twins
-
Ling, C.; Poulsen, P.; Carlsson, E.; Ridderstrale, M.; Almgren, P.; Wojtaszewski, J.; Beck-nielsen, H.; Groop, L.; Vaag, A. Multiple environmental and genetic factors influence skeletal muscle PGC-1 and PGC-1 gene expression in twins. J. Clin. Invest., 2004, 114, 1518-1526
-
(2004)
J. Clin. Invest
, vol.114
, pp. 1518-1526
-
-
Ling, C.1
Poulsen, P.2
Carlsson, E.3
Ridderstrale, M.4
Almgren, P.5
Wojtaszewski, J.6
Beck-Nielsen, H.7
Groop, L.8
Vaag, A.9
-
44
-
-
21744442902
-
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis
-
Li, F.; Wang, Y.; Zeller, K. I.; Potter, J. J.; Wonsey, D. R.; O'Donnell, K. A.; Kim, J.-W.; Yustein, J. T.; Lee, L. A.; Dang, C. V. Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol. Cell. Biol., 2005, 25, 6225-6234
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 6225-6234
-
-
Li, F.1
Wang, Y.2
Zeller, K.I.3
Potter, J.J.4
Wonsey, D.R.5
O'donnell, K.A.6
Kim, J.-W.7
Yustein, J.T.8
Lee, L.A.9
Dang, C.V.10
-
45
-
-
84861302910
-
Mitochondrial structure, function and dynamics are temporally controlled by c-myc
-
Graves, J. A.; Wang, Y.; Sims-Lucas, S.; Cherok, E.; Rothermund, K.; Branca, M. F.; Elster, J.; Beer-Stolz, D.; Van Houten, B.; Vockley, J.; Prochownik, E. V. Mitochondrial structure, function and dynamics are temporally controlled by c-myc. PLoS One, 2012, 7, e37699
-
(2012)
PLoS One
, vol.7
, pp. e37699
-
-
Graves, J.A.1
Wang, Y.2
Sims-Lucas, S.3
Cherok, E.4
Rothermund, K.5
Branca, M.F.6
Elster, J.7
Beer-Stolz, D.8
Van Houten, B.9
Vockley, J.10
Prochownik, E.V.11
-
46
-
-
77951839683
-
Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice
-
Ahuja, P.; Zhao, P.; Angelis, E.; Ruan, H.; Korge, P.; Olson, A.; Wang, Y.; Jin, E. S.; Jeffrey, F. M.; Portman, M.; Maclellan, W. R. Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. J. Clin. Invest., 2010, 120, 1494-1505
-
(2010)
J. Clin. Invest
, vol.120
, pp. 1494-1505
-
-
Ahuja, P.1
Zhao, P.2
Angelis, E.3
Ruan, H.4
Korge, P.5
Olson, A.6
Wang, Y.7
Jin, E.S.8
Jeffrey, F.M.9
Portman, M.10
Maclellan, W.R.11
-
47
-
-
67651159365
-
Transcriptional control of mitochondrial biogenesis and function
-
Hock, M. B.; Kralli, A. Transcriptional control of mitochondrial biogenesis and function. Annu. Rev. Physiol., 2009, 71, 177-203
-
(2009)
Annu. Rev. Physiol
, vol.71
, pp. 177-203
-
-
Hock, M.B.1
Kralli, A.2
-
48
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
Canto, C.; Gerhart-Hines, Z.; Feige, J. N.; Lagouge, M.; Noriega, L.; Milne, J. C.; Elliott, P. J.; Puigserver, P.; Auwerx, J. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature, 2009, 458, 1056-1060
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
49
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers, J. T.; Lerin, C.; Haas, W.; Gygi, S. P.; Spiegelman, B. M.; Puigserver, P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature, 2005, 434, 113-118
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
50
-
-
34247259630
-
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha
-
Gerhart-Hines, Z.; Rodgers, J. T.; Bare, O.; Lerin, C.; Kim, S.-H.; Mostoslavsky, R.; Alt, F. W.; Wu, Z.; Puigserver, P. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J., 2007, 26, 1913-1923
-
(2007)
EMBO J
, vol.26
, pp. 1913-1923
-
-
Gerhart-Hines, Z.1
Rodgers, J.T.2
Bare, O.3
Lerin, C.4
Kim, S.-H.5
Mostoslavsky, R.6
Alt, F.W.7
Wu, Z.8
Puigserver, P.9
-
51
-
-
84896739647
-
Small molecule SIRT1 activators for the treatment of aging and age-related diseases
-
Hubbard, B. P.; Sinclair, D. A. Small molecule SIRT1 activators for the treatment of aging and age-related diseases. Trends Pharmacol. Sci., 2014, 35, 146-154
-
(2014)
Trends Pharmacol. Sci
, vol.35
, pp. 146-154
-
-
Hubbard, B.P.1
Sinclair, D.A.2
-
52
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis, M. C.; Sinclair, D. A. Mammalian sirtuins: biological insights and disease relevance. Annu. Rev. Pathol., 2010, 5, 253-295
-
(2010)
Annu. Rev. Pathol
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
53
-
-
77955499804
-
Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha
-
Lim, J.H.; Lee, Y.M.; Chun, Y.S.; Chen, J.; Kim, J.E.; Park, J.W. Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha. Mol. Cell., 2010, 38, 864-878
-
(2010)
Mol. Cell
, vol.38
, pp. 864-878
-
-
Lim, J.H.1
Lee, Y.M.2
Chun, Y.S.3
Chen, J.4
Kim, J.E.5
Park, J.W.6
-
54
-
-
84893442805
-
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
-
Gomes, A. P.; Price, N. L.; Ling, A. J. Y.; Moslehi, J. J.; Montgomery, M. K.; Rajman, L.; White, J. P.; Teodoro, J. S.; Wrann, C. D.; Hubbard, B. P.; Mercken, E. M.; Palmeira, C. M.; de Cabo, R.; Rolo, A. P.; Turner, N.; Bell, E. L.; Sinclair, D. A. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell, 2013, 155, 1624-1638
-
(2013)
Cell
, vol.155
, pp. 1624-1638
-
-
Gomes, A.P.1
Price, N.L.2
Ling, A.J.Y.3
Moslehi, J.J.4
Montgomery, M.K.5
Rajman, L.6
White, J.P.7
Teodoro, J.S.8
Wrann, C.D.9
Hubbard, B.P.10
Mercken, E.M.11
Palmeira, C.M.12
De Cabo, R.13
Rolo, A.P.14
Turner, N.15
Bell, E.L.16
Sinclair, D.A.17
-
55
-
-
54849425547
-
Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation
-
Feige, J. N.; Lagouge, M.; Canto, C.; Strehle, A.; Houten, S. M.; Milne, J. C.; Lambert, P. D.; Mataki, C.; Elliott, P. J.; Auwerx, J. Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation. Cell Metab., 2008, 8, 347-358
-
(2008)
Cell Metab
, vol.8
, pp. 347-358
-
-
Feige, J.N.1
Lagouge, M.2
Canto, C.3
Strehle, A.4
Houten, S.M.5
Milne, J.C.6
Lambert, P.D.7
Mataki, C.8
Elliott, P.J.9
Auwerx, J.10
-
56
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
-
Lagouge, M.; Argmann, C.; Gerhart-Hines, Z.; Meziane, H.; Lerin, C.; Daussin, F.; Messadeq, N.; Milne, J.; Lambert, P.; Elliott, P.; Geny, B.; Laakso, M.; Puigserver, P.; Auwerx, J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell, 2006, 127, 1109-1122
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
57
-
-
63449112017
-
Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
-
Purushotham, A.; Schug, T. T.; Xu, Q.; Surapureddi, S.; Guo, X.; Li, X. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab., 2009, 9, 327-338
-
(2009)
Cell Metab
, vol.9
, pp. 327-338
-
-
Purushotham, A.1
Schug, T.T.2
Xu, Q.3
Surapureddi, S.4
Guo, X.5
Li, X.6
-
58
-
-
33745962138
-
Therapeutic potential of resveratrol: The in Vvvo evidence
-
Baur, J. A.; Sinclair, D. A. Therapeutic potential of resveratrol: the in Vvvo evidence. Nat. Rev. Drug. Discov., 2006, 5, 493-506
-
(2006)
Nat. Rev. Drug. Discov
, vol.5
, pp. 493-506
-
-
Baur, J.A.1
Sinclair, D.A.2
-
59
-
-
84860477354
-
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
-
Price, N. L.; Gomes, A. P.; Ling, A. J.; Duarte, F. V; Martin-Montalvo, A.; North, B. J.; Agarwal, B.; Ye, L.; Ramadori, G.; Teodoro, J. S.; Hubbard, B. P.; Varela, A. T.; Davis, J. G.; Varamini, B.; Hafner, A.; Moaddel, R.; Rolo, A. P.; Coppari, R.; Palmeira, C. M.; de Cabo, R.; Baur, J. A.; Sinclair, D. A. SIRT1 Is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab., 2012, 15, 675-690
-
(2012)
Cell Metab
, vol.15
, pp. 675-690
-
-
Price, N.L.1
Gomes, A.P.2
Ling, A.J.3
Duarte, F.V.4
Martin-Montalvo, A.5
North, B.J.6
Agarwal, B.7
Ye, L.8
Ramadori, G.9
Teodoro, J.S.10
Hubbard, B.P.11
Varela, A.T.12
Davis, J.G.13
Varamini, B.14
Hafner, A.15
Moaddel, R.16
Rolo, A.P.17
Coppari, R.18
Palmeira, C.M.19
De Cabo, R.20
Baur, J.A.21
Sinclair, D.A.22
more..
-
60
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen, H. Y.; Miller, C.; Bitterman, K. J.; Wall, N. R.; Hekking, B.; Kessler, B.; Howitz, K. T.; Gorospe, M.; de Cabo, R.; Sinclair, D. A. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science, 2004, 305, 390-392
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
61
-
-
73449133720
-
Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes
-
Hsu, C. P.; Hariharan, N.; Alcendor, R. R.; Oka, S.; Sadoshima, J. Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes. Autophagy, 2009, 5, 1229-1231
-
(2009)
Autophagy
, vol.5
, pp. 1229-1231
-
-
Hsu, C.P.1
Hariharan, N.2
Alcendor, R.R.3
Oka, S.4
Sadoshima, J.5
-
62
-
-
84861722850
-
Nicotinamide-induced mitophagy: Event mediated by high NAD+/NADH ratio and SIRT1 protein activation
-
Jang, S.-Y.; Kang, H. T.; Hwang, E. S. Nicotinamide-induced mitophagy: event mediated by high NAD+/NADH ratio and SIRT1 protein activation. J. Biol. Chem., 2012, 287, 19304-19314
-
(2012)
J. Biol. Chem
, vol.287
, pp. 19304-19314
-
-
Jang, S.-Y.1
Kang, H.T.2
Hwang, E.S.3
-
63
-
-
83455206803
-
Targeting sirtuin 1 to improve metabolism: All you need is NAD(+)
-
Canto, C.; Auwerx, J. Targeting sirtuin 1 to improve metabolism: all you need is NAD(+) Pharmacol. Rev., 2012, 64, 166-187
-
(2012)
Pharmacol.Rev
, vol.64
, pp. 166-187
-
-
Canto, C.1
Auwerx, J.2
-
64
-
-
1542618348
-
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
-
Shaw, R. J.; Kosmatka, M.; Bardeesy, N.; Hurley, R. L.; Witters, L. A.; DePinho, R. A.; Cantley, L. C. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl. Acad. Sci. U.S.A., 2004, 101, 3329-3335
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 3329-3335
-
-
Shaw, R.J.1
Kosmatka, M.2
Bardeesy, N.3
Hurley, R.L.4
Witters, L.A.5
Depinho, R.A.6
Cantley, L.C.7
-
65
-
-
77249156847
-
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
-
Canto, C.; Jiang, L. Q.; Deshmukh, A. S.; Mataki, C.; Coste, A.; Lagouge, M.; Zierath, J. R.; Auwerx, J. Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle. Cell Metab., 2010, 11, 213-219
-
(2010)
Cell Metab
, vol.11
, pp. 213-219
-
-
Canto, C.1
Jiang, L.Q.2
Deshmukh, A.S.3
Mataki, C.4
Coste, A.5
Lagouge, M.6
Zierath, J.R.7
Auwerx, J.8
-
66
-
-
55549096745
-
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1,possible role in AMP-activated protein kinase activation
-
Lan, F.; Cacicedo, J. M.; Ruderman, N.; Ido, Y. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. possible role in AMP-activated protein kinase activation. J. Biol. Chem., 2008, 283, 27628-27635
-
(2008)
J. Biol. Chem
, vol.283
, pp. 27628-27635
-
-
Lan, F.1
Cacicedo, J.M.2
Ruderman, N.3
Ido, Y.4
-
67
-
-
7244253081
-
Nrf2-Keap1 defines a physiologically important stress response mechanism
-
Motohashi, H.; Yamamoto, M. Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol. Med., 2004, 10, 549-557
-
(2004)
Trends Mol. Med
, vol.10
, pp. 549-557
-
-
Motohashi, H.1
Yamamoto, M.2
-
68
-
-
3042835514
-
Regulation of antioxidant response elementdependent induction of detoxifying enzyme synthesis
-
Jaiswal, A. K. Regulation of antioxidant response elementdependent induction of detoxifying enzyme synthesis. Methods Enzym., 2004, 378, 221-238
-
(2004)
Methods Enzym
, vol.378
, pp. 221-238
-
-
Jaiswal, A.K.1
-
69
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 Gene
-
Venugopal, R.; Jaiswal, A. K. Nrf1 and Nrf2 positively and c-Fos and fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 Gene. Proc. Natl. Acad. Sci. U.S.A., 1996, 93, 14960-14965
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
70
-
-
4544360319
-
Regulation of heme oxygenase-1 gene transcription: Recent advances and highlights from the international conference (Uppsala, 2003) on heme oxygenase
-
Alam, J.; Igarashi, K.; Immenschuh, S.; Shibahara, S.; Tyrrell, R. M. Regulation of heme oxygenase-1 gene transcription: recent advances and highlights from the international conference (Uppsala, 2003) on heme oxygenase. Antioxid. Redox Signal., 2004, 6, 924-933
-
(2004)
Antioxid. Redox Signal
, vol.6
, pp. 924-933
-
-
Alam, J.1
Igarashi, K.2
Immenschuh, S.3
Shibahara, S.4
Tyrrell, R.M.5
-
71
-
-
14044254798
-
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
-
Kobayashi, M.; Yamamoto, M. Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid. Redox Signal., 2005, 7, 385-394
-
(2005)
Antioxid. Redox Signal
, vol.7
, pp. 385-394
-
-
Kobayashi, M.1
Yamamoto, M.2
-
72
-
-
58149328569
-
Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1
-
Piantadosi, C. A.; Carraway, M. S.; Babiker, A.; Suliman, H. B. Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. Circ. Res., 2008, 103, 1232-1240
-
(2008)
Circ. Res
, vol.103
, pp. 1232-1240
-
-
Piantadosi, C.A.1
Carraway, M.S.2
Babiker, A.3
Suliman, H.B.4
-
73
-
-
37549032763
-
An autoregulatory loop between Stress sensors INrf2 and Nrf2 controls their cellular abundance
-
Lee, O.-H.; Jain, A. K.; Papusha, V.; Jaiswal, A. K. An autoregulatory loop between Stress sensors INrf2 and Nrf2 controls their cellular abundance. J. Biol. Chem., 2007, 282, 36412-36420
-
(2007)
J. Biol. Chem
, vol.282
, pp. 36412-36420
-
-
Lee, O.-H.1
Jain, A.K.2
Papusha, V.3
Jaiswal, A.K.4
-
74
-
-
1942455887
-
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
-
Itoh, K.; Tong, K. I.; Yamamoto, M. Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic. Biol. Med., 2004, 36, 1208-1213
-
(2004)
Free Radic. Biol. Med
, vol.36
, pp. 1208-1213
-
-
Itoh, K.1
Tong, K.I.2
Yamamoto, M.3
-
75
-
-
25444449520
-
Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1
-
Nguyen, T.; Sherratt, P. J.; Nioi, P.; Yang, C. S.; Pickett, C. B. Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1. J. Biol. Chem., 2005, 280, 32485-32492
-
(2005)
J. Biol. Chem
, vol.280
, pp. 32485-32492
-
-
Nguyen, T.1
Sherratt, P.J.2
Nioi, P.3
Yang, C.S.4
Pickett, C.B.5
-
76
-
-
77649242989
-
P62, an autophagy hero or culprit
-
Rusten, T. E.; Stenmark, H. p62, an autophagy hero or culprit Nat. Cell. Biol., 2010, 12, 207 209
-
(2010)
Nat.Cell.Biol
, vol.12
, pp. 207-209
-
-
Rusten, T.E.1
Stenmark, H.2
-
77
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
Komatsu, M.; Kurokawa, H.; Waguri, S.; Taguchi, K.; Kobayashi, A.; Ichimura, Y.; Sou, Y.-S.; Ueno, I.; Sakamoto, A.; Tong, K. I.; Kim, M.; Nishito, Y.; Iemura, S.; Natsume, T.; Ueno, T.; Kominami, E.; Motohashi, H.; Tanaka, K.; Yamamoto, M. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat. Cell. Biol., 2010, 12, 213-223
-
(2010)
Nat. Cell. Biol
, vol.12
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
Taguchi, K.4
Kobayashi, A.5
Ichimura, Y.6
Sou, Y.-S.7
Ueno, I.8
Sakamoto, A.9
Tong, K.I.10
Kim, M.11
Nishito, Y.12
Iemura, S.13
Natsume, T.14
Ueno, T.15
Kominami, E.16
Motohashi, H.17
Tanaka, K.18
Yamamoto, M.19
-
78
-
-
77953366801
-
A noncanonical mechanism of nrf2 activation by autophagy deficiency: Direct interaction between keap1 and p62
-
Lau, A.; Wang, X.-J.; Zhao, F.; Villeneuve, N. F.; Wu, T.; Jiang, T.; Sun, Z.; White, E.; Zhang, D. D. A noncanonical mechanism of nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Mol. Cell. Biol., 2010, 30, 3275-3285
-
(2010)
Mol.Cell.Biol
, vol.30
, pp. 3275-3285
-
-
Lau, A.1
Wang, X.-J.2
Zhao, F.3
Villeneuve, N.F.4
Wu, T.5
Jiang, T.6
Sun, Z.7
White, E.8
Zhang, D.D.9
-
79
-
-
84875061355
-
Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice
-
Zhang, Y.-K. J.; Wu, K. C.; Klaassen, C. D. Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice. PloS One, 2013, 8, e59122
-
(2013)
PloS One
, vol.8
, pp. e59122
-
-
Zhang, Y.-K.J.1
Wu, K.C.2
Klaassen, C.D.3
-
80
-
-
79952749190
-
NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1
-
Kim, T.-H.; Hur, E.-G.; Kang, S.-J.; Kim, J.-A.; Thapa, D.; Lee, Y. M.; Ku, S. K.; Jung, Y.; Kwak, M.-K. NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1. Cancer Res., 2011, 71, 2260-2275
-
(2011)
Cancer Res
, vol.71
, pp. 2260-2275
-
-
Kim, T.-H.1
Hur, E.-G.2
Kang, S.-J.3
Kim, J.-A.4
Thapa, D.5
Lee, Y.M.6
Ku, S.K.7
Jung, Y.8
Kwak, M.-K.9
-
81
-
-
84964999321
-
Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration
-
Holmstrom, K. M.; Baird, L.; Zhang, Y.; Hargreaves, I.; Chalasani, A.; Land, J. M.; Stanyer, L.; Yamamoto, M.; Dinkova-Kostova, A. T.; Abramov, A. Y. Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration. Biol. Open., 2013, 2, 761-770
-
(2013)
Biol. Open
, vol.2
, pp. 761-770
-
-
Holmstrom, K.M.1
Baird, L.2
Zhang, Y.3
Hargreaves, I.4
Chalasani, A.5
Land, J.M.6
Stanyer, L.7
Yamamoto, M.8
Dinkova-Kostova, A.T.9
Abramov, A.Y.10
-
82
-
-
0141621061
-
NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex i inhibitors and increased concentrations of intracellular calcium in primary cortical neurons
-
Lee, J.-M.; Shih, A. Y.; Murphy, T. H.; Johnson, J. A. NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. J. Biol. Chem., 2003, 278, 37948-37956
-
(2003)
J. Biol. Chem
, vol.278
, pp. 37948-37956
-
-
Lee, J.-M.1
Shih, A.Y.2
Murphy, T.H.3
Johnson, J.A.4
-
83
-
-
34447633192
-
Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptorinduced motor neuron apoptosis
-
Pehar, M.; Vargas, M. R.; Robinson, K. M.; Cassina, P.; Diaz-Amarilla, P. J.; Hagen, T. M.; Radi, R.; Barbeito, L.; Beckman, J. S. Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptorinduced motor neuron apoptosis. J. Neurosci., 2007, 27, 7777-7785
-
(2007)
J. Neurosci
, vol.27
, pp. 7777-7785
-
-
Pehar, M.1
Vargas, M.R.2
Robinson, K.M.3
Cassina, P.4
Diaz-Amarilla, P.J.5
Hagen, T.M.6
Radi, R.7
Barbeito, L.8
Beckman, J.S.9
-
84
-
-
78751644875
-
Brain Mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition
-
Greco, T.; Fiskum, G. Brain Mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition. J. Bioenerg. Biomembr., 2010, 42, 491-497
-
(2010)
J. Bioenerg. Biomembr
, vol.42
, pp. 491-497
-
-
Greco, T.1
Fiskum, G.2
-
85
-
-
84860389335
-
Curcumin prevents Cr(VI)-induced renal oxidant damage by a mitochondrial pathway
-
Molina-Jijon, E.; Tapia, E.; Zazueta, C.; El Hafidi, M.; Zatarain-Barron, Z. L.; Hernandez-Pando, R.; Medina-Campos, O. N.; Zarco-Marquez, G.; Torres, I.; Pedraza-Chaverri, J. Curcumin prevents Cr(VI)-induced renal oxidant damage by a mitochondrial pathway. Free Radic. Biol. Med., 2011, 51, 1543-1557
-
(2011)
Free Radic. Biol. Med
, vol.51
, pp. 1543-1557
-
-
Molina-Jijon, E.1
Tapia, E.2
Zazueta, C.3
El Hafidi, M.4
Zatarain-Barron, Z.L.5
Hernandez-Pando, R.6
Medina-Campos, O.N.7
Zarco-Marquez, G.8
Torres, I.9
Pedraza-Chaverri, J.10
-
86
-
-
84860189098
-
Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal staphylococcus aureus sepsis
-
MacGarvey, N. C.; Suliman, H. B.; Bartz, R. R.; Fu, P.; Withers, C. M.; Welty-Wolf, K. E.; Piantadosi, C. A. Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal staphylococcus aureus sepsis. Am. J. Respir. Crit. Care Med., 2012, 185, 851-861
-
(2012)
Am. J. Respir. Crit. Care Med
, vol.185
, pp. 851-861
-
-
Macgarvey, N.C.1
Suliman, H.B.2
Bartz, R.R.3
Fu, P.4
Withers, C.M.5
Welty-Wolf, K.E.6
Piantadosi, C.A.7
-
87
-
-
66749132810
-
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription
-
Yang, L.; Calingasan, N. Y.; Thomas, B.; Chaturvedi, R. K.; Kiaei, M.; Wille, E. J.; Liby, K. T.; Williams, C.; Royce, D.; Risingsong, R.; Musiek, E. S.; Morrow, J. D.; Sporn, M.; Beal, M. F. Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. PLoS One, 2009, 4, e5757
-
(2009)
PLoS One
, vol.4
, pp. e5757
-
-
Yang, L.1
Calingasan, N.Y.2
Thomas, B.3
Chaturvedi, R.K.4
Kiaei, M.5
Wille, E.J.6
Liby, K.T.7
Williams, C.8
Royce, D.9
Risingsong, R.10
Musiek, E.S.11
Morrow, J.D.12
Sporn, M.13
Beal, M.F.14
-
88
-
-
83255163155
-
Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis
-
Gomes, A. P.; Duarte, F. V.; Nunes, P.; Hubbard, B. P.; Teodoro, J. S.; Varela, A. T.; Jones, J. G.; Sinclair, D. A.; Palmeira, C. M.; Rolo, A. P. Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis. Biochim. Biophys. Acta., 2012, 1822, 185-195
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 185-195
-
-
Gomes, A.P.1
Duarte, F.V.2
Nunes, P.3
Hubbard, B.P.4
Teodoro, J.S.5
Varela, A.T.6
Jones, J.G.7
Sinclair, D.A.8
Palmeira, C.M.9
Rolo, A.P.10
-
89
-
-
84861189612
-
Berberine activates Nrf2 nuclear translocation and protects against oxidative damage via a phosphatidylinositol 3-kinase/Akt-dependent mechanism in NSC34 motor neuron-like Cells
-
Hsu, Y.Y.; Chen, C.S.; Wu, S.N.; Jong, Y.J.; Lo, Y.C. Berberine activates Nrf2 nuclear translocation and protects against oxidative damage via a phosphatidylinositol 3-kinase/Akt-dependent mechanism in NSC34 motor neuron-like Cells. Eur. J. Pharmacol. Sci., 2012, 46, 415-425
-
(2012)
Eur. J. Pharmacol. Sci
, vol.46
, pp. 415-425
-
-
Hsu, Y.Y.1
Chen, C.S.2
Wu, S.N.3
Jong, Y.J.4
Lo, Y.C.5
-
90
-
-
84874564486
-
Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin
-
Jin, Y. N.; Yu, Y. V; Gundemir, S.; Jo, C.; Cui, M.; Tieu, K.; Johnson, G. V. W. Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin. PLoS One, 2013, 8, e57932
-
(2013)
PLoS One
, vol.8
, pp. e57932
-
-
Jin, Y.N.1
Yu, Y.V.2
Gundemir, S.3
Jo, C.4
Cui, M.5
Tieu, K.6
Johnson, G.V.W.7
-
91
-
-
84863764614
-
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming
-
Mitsuishi, Y.; Taguchi, K.; Kawatani, Y.; Shibata, T.; Nukiwa, T.; Aburatani, H.; Yamamoto, M.; Motohashi, H. Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. Cancer Cell, 2012, 22, 66-79
-
(2012)
Cancer Cell
, vol.22
, pp. 66-79
-
-
Mitsuishi, Y.1
Taguchi, K.2
Kawatani, Y.3
Shibata, T.4
Nukiwa, T.5
Aburatani, H.6
Yamamoto, M.7
Motohashi, H.8
-
92
-
-
66749112860
-
Genetic versus chemoprotective activation of Nrf2 signaling: Overlapping yet distinct gene expression profiles between keap1 knockout and triterpenoid-treated mice
-
Yates, M. S.; Tran, Q. T.; Dolan, P. M.; Osburn, W. O.; Shin, S.; McCulloch, C. C.; Silkworth, J. B.; Taguchi, K.; Yamamoto, M.; Williams, C. R.; Liby, K. T.; Sporn, M. B.; Sutter, T. R.; Kensler, T. W. Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between keap1 knockout and triterpenoid-treated mice. Carcinogenesis, 2009, 30, 1024-1031
-
(2009)
Carcinogenesis
, vol.30
, pp. 1024-1031
-
-
Yates, M.S.1
Tran, Q.T.2
Dolan, P.M.3
Osburn, W.O.4
Shin, S.5
McCulloch, C.C.6
Silkworth, J.B.7
Taguchi, K.8
Yamamoto, M.9
Williams, C.R.10
Liby, K.T.11
Sporn, M.B.12
Sutter, T.R.13
Kensler, T.W.14
-
93
-
-
77953290236
-
Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver
-
Kitteringham, N. R.; Abdullah, A.; Walsh, J.; Randle, L.; Jenkins, R. E.; Sison, R.; Goldring, C. E.; Powell, H.; Sanderson, C.; Williams, S.; Higgins, L.; Yamamoto, M.; Hayes, J.; Park, B. K. Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver. J. Proteomics, 2010, 73, 1612-1631
-
(2010)
J. Proteomics
, vol.73
, pp. 1612-1631
-
-
Kitteringham, N.R.1
Abdullah, A.2
Walsh, J.3
Randle, L.4
Jenkins, R.E.5
Sison, R.6
Goldring, C.E.7
Powell, H.8
Sanderson, C.9
Williams, S.10
Higgins, L.11
Yamamoto, M.12
Hayes, J.13
Park, B.K.14
-
94
-
-
42449111723
-
NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a highfat Diet
-
Tanaka, Y.; Aleksunes, L. M.; Yeager, R. L.; Gyamfi, M. A.; Esterly, N.; Guo, G. L.; Klaassen, C. D. NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a highfat Diet. J. Pharmacol. Exp. Ther., 2008, 325, 655-664
-
(2008)
J. Pharmacol. Exp. Ther
, vol.325
, pp. 655-664
-
-
Tanaka, Y.1
Aleksunes, L.M.2
Yeager, R.L.3
Gyamfi, M.A.4
Esterly, N.5
Guo, G.L.6
Klaassen, C.D.7
-
95
-
-
57249104720
-
Nrf2 is critical in defense against high glucose-induced oxidative damage in ardiomyocytes
-
He, X.; Kan, H.; Cai, L.; Ma, Q. Nrf2 Is critical in defense against high glucose-induced oxidative damage in ardiomyocytes. J. Mol. Cell Cardiol., 2009, 46, 47-58
-
(2009)
J. Mol. Cell Cardiol
, vol.46
, pp. 47-58
-
-
He, X.1
Kan, H.2
Cai, L.3
Ma, Q.4
-
96
-
-
79551575483
-
Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo
-
Tan, Y.; Ichikawa, T.; Li, J.; Si, Q.; Yang, H.; Chen, X.; Goldblatt, C. S.; Meyer, C. J.; Li, X.; Cai, L.; Cui, T. Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo. Diabetes, 2011, 60, 625-633
-
(2011)
Diabetes
, vol.60
, pp. 625-633
-
-
Tan, Y.1
Ichikawa, T.2
Li, J.3
Si, Q.4
Yang, H.5
Chen, X.6
Goldblatt, C.S.7
Meyer, C.J.8
Li, X.9
Cai, L.10
Cui, T.11
-
97
-
-
77953741269
-
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
-
Ungvari, Z.; Bagi, Z.; Feher, A.; Recchia, F. A.; Sonntag, W. E.; Pearson, K.; de Cabo, R.; Csiszar, A. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am. J. Physiol. Hear. Circ. Physiol., 2010, 299, H18-H24
-
(2010)
Am. J. Physiol. Hear. Circ. Physiol
, vol.299
, pp. H18-H24
-
-
Ungvari, Z.1
Bagi, Z.2
Feher, A.3
Recchia, F.A.4
Sonntag, W.E.5
Pearson, K.6
De Cabo, R.7
Csiszar, A.8
-
98
-
-
77949770480
-
Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice
-
Aleksunes, L. M.; Reisman, S. A.; Yeager, R. L.; Goedken, M. J.; Klaassen, C. D. Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice. J. Pharmacol. Exp. Ther., 2010, 333, 140-151
-
(2010)
J. Pharmacol. Exp. Ther
, vol.333
, pp. 140-151
-
-
Aleksunes, L.M.1
Reisman, S.A.2
Yeager, R.L.3
Goedken, M.J.4
Klaassen, C.D.5
-
99
-
-
77952952816
-
Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine-and choline-deficient diet
-
Zhang, Y.-K. J.; Yeager, R. L.; Tanaka, Y.; Klaassen, C. D. Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine-and choline-deficient diet. Toxicol. Appl. Pharmacol., 2010, 245, 326-334
-
(2010)
Toxicol. Appl. Pharmacol
, vol.245
, pp. 326-334
-
-
Zhang, Y.-K.J.1
Yeager, R.L.2
Tanaka, Y.3
Klaassen, C.D.4
-
100
-
-
70349140473
-
Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide
-
Shin, S.; Wakabayashi, J.; Yates, M. S.; Wakabayashi, N.; Dolan, P. M.; Aja, S.; Liby, K. T.; Sporn, M. B.; Yamamoto, M.; Kensler, T. W. Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide. Eur. J. Pharmacol., 2009, 620, 138-144
-
(2009)
Eur. J. Pharmacol
, vol.620
, pp. 138-144
-
-
Shin, S.1
Wakabayashi, J.2
Yates, M.S.3
Wakabayashi, N.4
Dolan, P.M.5
Aja, S.6
Liby, K.T.7
Sporn, M.B.8
Yamamoto, M.9
Kensler, T.W.10
-
101
-
-
79953810587
-
Oltipraz upregulates the nuclear factor (erythroid-derived 2)-like 2 [corrected](NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice
-
Yu, Z.; Shao, W.; Chiang, Y.; Foltz, W.; Zhang, Z.; Ling, W.; Fantus, I. G.; Jin, T. Oltipraz upregulates the nuclear factor (erythroid-derived 2)-like 2 [corrected](NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice. Diabetologia, 2011, 54, 922-934
-
(2011)
Diabetologia
, vol.54
, pp. 922-934
-
-
Yu, Z.1
Shao, W.2
Chiang, Y.3
Foltz, W.4
Zhang, Z.5
Ling, W.6
Fantus, I.G.7
Jin, T.8
-
102
-
-
84880327440
-
Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice
-
Lee, C. S.; Ho, D. V; Chan, J. Y. Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice. FEBS J., 2013, 280, 3609-3620
-
(2013)
FEBS J
, vol.280
, pp. 3609-3620
-
-
Lee, C.S.1
Ho, D.V.2
Chan, J.Y.3
-
103
-
-
84867418393
-
Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet
-
Zhang, Y.-K. J.; Wu, K. C.; Liu, J.; Klaassen, C. D. Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet. Toxicol. Appl. Pharmacol., 2012, 264, 305-314
-
(2012)
Toxicol. Appl. Pharmacol
, vol.264
, pp. 305-314
-
-
Zhang, Y.-K.J.1
Wu, K.C.2
Liu, J.3
Klaassen, C.D.4
-
104
-
-
77950553993
-
Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against dietinduced obesity
-
Pi, J.; Leung, L.; Xue, P.; Wang, W.; Hou, Y.; Liu, D.; Yehuda-Shnaidman, E.; Lee, C.; Lau, J.; Kurtz, T. W.; Chan, J. Y. Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against dietinduced obesity. J. Biol. Chem., 2010, 285, 9292-9300
-
(2010)
J. Biol. Chem
, vol.285
, pp. 9292-9300
-
-
Pi, J.1
Leung, L.2
Xue, P.3
Wang, W.4
Hou, Y.5
Liu, D.6
Yehuda-Shnaidman, E.7
Lee, C.8
Lau, J.9
Kurtz, T.W.10
Chan, J.Y.11
-
105
-
-
84865287281
-
Keap1 degradation by autophagy for the maintenance of redox homeostasis
-
Taguchi, K.; Fujikawa, N.; Komatsu, M.; Ishii, T.; Unno, M.; Akaike, T.; Motohashi, H.; Yamamoto, M. Keap1 degradation by autophagy for the maintenance of redox homeostasis. Proc. Natl. Acad. Sci. U.S.A., 2012, 109, 13561-13566
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 13561-13566
-
-
Taguchi, K.1
Fujikawa, N.2
Komatsu, M.3
Ishii, T.4
Unno, M.5
Akaike, T.6
Motohashi, H.7
Yamamoto, M.8
-
106
-
-
84892956865
-
Nrf2 signaling is impaired in the aging RPE given an oxidative insult
-
Sachdeva, M. M.; Cano, M.; Handa, J. T. Nrf2 signaling is impaired in the aging RPE given an oxidative insult. Exp. Eye Res., 2014, 119, 111-114
-
(2014)
Exp. Eye Res
, vol.119
, pp. 111-114
-
-
Sachdeva, M.M.1
Cano, M.2
Handa, J.T.3
-
107
-
-
37749024370
-
Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in drosophila
-
Sykiotis, G. P.; Bohmann, D. Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in drosophila. Dev. Cell, 2008, 14, 76-85
-
(2008)
Dev. Cell
, vol.14
, pp. 76-85
-
-
Sykiotis, G.P.1
Bohmann, D.2
-
108
-
-
84864411067
-
Nrf2-ARE pathway regulates induction of sestrin-2 expression
-
Shin, B. Y.; Jin, S. H.; Cho, I. J.; Ki, S. H. Nrf2-ARE pathway regulates induction of sestrin-2 expression. Free Radic. Biol. Med., 2012, 53, 834-841
-
(2012)
Free Radic. Biol. Med
, vol.53
, pp. 834-841
-
-
Shin, B.Y.1
Jin, S.H.2
Cho, I.J.3
Ki, S.H.4
-
109
-
-
84872137966
-
Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of keap1 and prevent oxidative liver damage
-
Bae, S. H.; Sung, S. H.; Oh, S. Y.; Lim, J. M.; Lee, S. K.; Park, Y. N.; Lee, H. E.; Kang, D.; Rhee, S. G. Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of keap1 and prevent oxidative liver damage. Cell Metab., 2013, 17, 73-84
-
(2013)
Cell Metab
, vol.17
, pp. 73-84
-
-
Bae, S.H.1
Sung, S.H.2
Oh, S.Y.3
Lim, J.M.4
Lee, S.K.5
Park, Y.N.6
Lee, H.E.7
Kang, D.8
Rhee, S.G.9
-
110
-
-
2142815107
-
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
-
Budanov, A. V; Sablina, A. A.; Feinstein, E.; Koonin, E. V; Chumakov, P. M. Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science, 2004, 304, 596-600
-
(2004)
Science
, vol.304
, pp. 596-600
-
-
Budanov, A.V.1
Sablina, A.A.2
Feinstein, E.3
Koonin, E.V.4
Chumakov, P.M.5
-
111
-
-
48449101433
-
P53 target genes sestrin1 and sestrin2 connect genotoxic stress and MTOR signaling
-
Budanov, A. V; Karin, M. P53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell, 2008, 134, 451-460
-
(2008)
Cell
, vol.134
, pp. 451-460
-
-
Budanov, A.V.1
Karin, M.2
-
112
-
-
77749264562
-
Sestrin as a feedback inhibitor of TOR that prevents agerelated pathologies
-
Lee, J. H.; Budanov, A. V; Park, E. J.; Birse, R.; Kim, T. E.; Perkins, G. A.; Ocorr, K.; Ellisman, M. H.; Bodmer, R.; Bier, E.; Karin, M. Sestrin as a feedback inhibitor of TOR that prevents agerelated pathologies. Science, 2010, 327, 1223-1228
-
(2010)
Science
, vol.327
, pp. 1223-1228
-
-
Lee, J.H.1
Budanov, A.V.2
Park, E.J.3
Birse, R.4
Kim, T.E.5
Perkins, G.A.6
Ocorr, K.7
Ellisman, M.H.8
Bodmer, R.9
Bier, E.10
Karin, M.11
-
113
-
-
84857412162
-
Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells
-
Sanli, T.; Linher-Melville, K.; Tsakiridis, T.; Singh, G. Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells. PLoS One, 2012, 7, e32035
-
(2012)
PLoS One
, vol.7
, pp. e32035
-
-
Sanli, T.1
Linher-Melville, K.2
Tsakiridis, T.3
Singh, G.4
-
114
-
-
84874945405
-
Sestrin2 integrates akt and mTOR signaling to protect cells against energetic stress-induced death
-
Ben-Sahra, I.; Dirat, B.; Laurent, K.; Puissant, A.; Auberger, P.; Budanov, A.; Tanti, J.-F.; Bost, F. Sestrin2 integrates akt and mTOR signaling to protect cells against energetic stress-induced death. Cell Death Differ., 2013, 20, 611-619
-
(2013)
Cell Death Differ
, vol.20
, pp. 611-619
-
-
Ben-Sahra, I.1
Dirat, B.2
Laurent, K.3
Puissant, A.4
Auberger, P.5
Budanov, A.6
Tanti, J.-F.7
Bost, F.8
-
115
-
-
84871342129
-
MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and forkhead box j3
-
Yamamoto, H.; Morino, K.; Nishio, Y.; Ugi, S.; Yoshizaki, T.; Kashiwagi, A.; Maegawa, H. MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and forkhead box j3. Am. J. Physiol. Endocrinol. Metab., 2012, 303, E1419-E1427
-
(2012)
Am. J. Physiol. Endocrinol. Metab
, vol.303
, pp. E1419-E1427
-
-
Yamamoto, H.1
Morino, K.2
Nishio, Y.3
Ugi, S.4
Yoshizaki, T.5
Kashiwagi, A.6
Maegawa, H.7
-
116
-
-
84886095617
-
MIRNAS: Their discovery, biogenesis and mechanism of action
-
Tetreault, N.; De Guire, V. miRNAs: Their discovery, biogenesis and mechanism of action. Clin. Biochem., 2013, 46, 842-845
-
(2013)
Clin. Biochem
, vol.46
, pp. 842-845
-
-
Tetreault, N.1
De Guire, V.2
-
117
-
-
69449097865
-
Regulation of autophagy by a beclin 1-targeted microRNA, MIR-30a, in cancer cells
-
Zhu, H.; Wu, H.; Liu, X.; Li, B.; Chen, Y.; Ren, X.; Liu, C.; Yang, J. Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in Cancer Cells. Autophagy, 2009, 5, 816-823
-
(2009)
Autophagy
, vol.5
, pp. 816-823
-
-
Zhu, H.1
Wu, H.2
Liu, X.3
Li, B.4
Chen, Y.5
Ren, X.6
Liu, C.7
Yang, J.8
-
118
-
-
79958737573
-
Nuclear outsourcing of RNA interference components to human mitochondria
-
Bandiera, S.; Ruberg, S.; Girard, M.; Cagnard, N.; Hanein, S.; Chretien, D.; Munnich, A.; Lyonnet, S.; Henrion-Caude, A. Nuclear outsourcing of RNA interference components to human mitochondria. PLoS One, 2011, 6, e20746
-
(2011)
PLoS One
, vol.6
, pp. e20746
-
-
Bandiera, S.1
Ruberg, S.2
Girard, M.3
Cagnard, N.4
Hanein, S.5
Chretien, D.6
Munnich, A.7
Lyonnet, S.8
Henrion-Caude, A.9
-
119
-
-
81255143302
-
MicroRNA-101 is a potent inhibitor of autophagy
-
Frankel, L. B.; Wen, J.; Lees, M.; Hoyer-Hansen, M.; Farkas, T.; Krogh, A.; Jaattela, M.; Lund, A. H. microRNA-101 is a potent inhibitor of autophagy. EMBO J., 2011, 30, 4628-4641
-
(2011)
EMBO J
, vol.30
, pp. 4628-4641
-
-
Frankel, L.B.1
Wen, J.2
Lees, M.3
Hoyer-Hansen, M.4
Farkas, T.5
Krogh, A.6
Jaattela, M.7
Lund, A.H.8
-
120
-
-
84869080120
-
Mitochondria: One of the destinations of MIRNAS
-
Sripada, L.; Tomar, D.; Singh, R. Mitochondria: One of the destinations of miRNAs. Mitochondrion, 2012, 12, 593-599
-
(2012)
Mitochondrion
, vol.12
, pp. 593-599
-
-
Sripada, L.1
Tomar, D.2
Singh, R.3
-
121
-
-
79959973301
-
MIR-204 regulates cardiomyocyte autophagy induced by ischemiareperfusion through LC3-II
-
Xiao, J.; Zhu, X.; He, B.; Zhang, Y.; Kang, B.; Wang, Z.; Ni, X. MiR-204 regulates cardiomyocyte autophagy induced by ischemiareperfusion through LC3-II. J. Biomed. Sci., 2011, 18, 35
-
(2011)
J. Biomed. Sci
, vol.18
, pp. 35
-
-
Xiao, J.1
Zhu, X.2
He, B.3
Zhang, Y.4
Kang, B.5
Wang, Z.6
Ni, X.7
-
122
-
-
84878975272
-
The role of microRNAs in mitochondria in cancer
-
Bienertova-Vasku, J.; Sana, J.; Slaby, O. The role of microRNAs in mitochondria in cancer. Cancer Lett., 2013, 336, 1-7
-
(2013)
Cancer Lett
, vol.336
, pp. 1-7
-
-
Bienertova-Vasku, J.1
Sana, J.2
Slaby, O.3
-
123
-
-
84906043443
-
Role of epigenetic mechanisms in the development of chronic complications of diabetes
-
Wegner, M.; Neddermann, D.; Piorunska-Stolzmann, M.; Jagodzinski, P. P. Role of epigenetic mechanisms in the development of chronic complications of diabetes. Diabetes Res. Clin. Pract., 2014, 105, 164-175
-
(2014)
Diabetes Res. Clin. Pract
, vol.105
, pp. 164-175
-
-
Wegner, M.1
Neddermann, D.2
Piorunska-Stolzmann, M.3
Jagodzinski, P.P.4
-
124
-
-
84858776574
-
MICRORNAS in metabolism and metabolic disorders
-
Rottiers, V.; Naar, A. M. MicroRNAs in metabolism and metabolic disorders. Nat. Rev. Mol. Cell Biol., 2012, 13, 239-250
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 239-250
-
-
Rottiers, V.1
Naar, A.M.2
-
125
-
-
84884587062
-
Paediatrics: Circulating MICRORNAS-predictors of obesity
-
Koch, L. Paediatrics: circulating microRNAs-predictors of obesity Nat. Rev. Endocrinol., 2013, 9, 565
-
(2013)
Nat.Rev. Endocrinol
, vol.9
, pp. 565
-
-
Koch, L.1
-
126
-
-
84885448790
-
Serum circulating MICRORNA profiling for identification of potential type 2 diabetes and obesity biomarkers
-
Pescador, N.; Perez-Barba, M.; Ibarra, J. M.; Corbaton, A.; Martinez-Larrad, M. T.; Serrano-Rios, M. Serum circulating microRNA profiling for identification of potential type 2 diabetes and obesity biomarkers. PLoS One, 2013, 8, e77251
-
(2013)
PLoS One
, vol.8
, pp. e77251
-
-
Pescador, N.1
Perez-Barba, M.2
Ibarra, J.M.3
Corbaton, A.4
Martinez-Larrad, M.T.5
Serrano-Rios, M.6
-
127
-
-
84883054093
-
Polymorphisms in lipid metabolism related MIRNA binding sites and risk of metabolics yndrome
-
Ye, Q.; Zhao, X.; Xu, K.; Li, Q.; Cheng, J.; Gao, Y.; Du, J.; Shi, H.; Zhou, L. Polymorphisms in lipid metabolism related miRNA binding sites and risk of metabolics yndrome. Gene, 2013, 528, 132-138
-
(2013)
Gene
, vol.528
, pp. 132-138
-
-
Ye, Q.1
Zhao, X.2
Xu, K.3
Li, Q.4
Cheng, J.5
Gao, Y.6
Du, J.7
Shi, H.8
Zhou, L.9
-
128
-
-
84894031528
-
Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic MIRNAS
-
Liang, T.; Liu, C.; Ye, Z. Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic miRNAs. PLoS One, 2013, 8, e80774
-
(2013)
PLoS One
, vol.8
, pp. e80774
-
-
Liang, T.1
Liu, C.2
Ye, Z.3
-
129
-
-
84880254076
-
Genetic regulation of human adipose MICRORNA expression and Its consequences for metabolic traits
-
Civelek, M.; Hagopian, R.; Pan, C.; Che, N.; Yang, W.-P.; Kayne, P. S.; Saleem, N. K.; Cederberg, H.; Kuusisto, J.; Gargalovic, P. S.; Kirchgessner, T. G.; Laakso, M.; Lusis, A. J. Genetic regulation of human adipose microRNA expression and Its consequences for metabolic traits. Hum. Mol. Genet., 2013, 22, 3023-3037
-
(2013)
Hum. Mol. Genet
, vol.22
, pp. 3023-3037
-
-
Civelek, M.1
Hagopian, R.2
Pan, C.3
Che, N.4
Yang, W.-P.5
Kayne, P.S.6
Saleem, N.K.7
Cederberg, H.8
Kuusisto, J.9
Gargalovic, P.S.10
Kirchgessner, T.G.11
Laakso, M.12
Lusis, A.J.13
-
130
-
-
77953780835
-
MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis
-
Najafi-Shoushtari, S. H.; Kristo, F.; Li, Y.; Shioda, T.; Cohen, D. E.; Gerszten, R. E.; Naar, A. M. MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science, 2010, 328, 1566-1569
-
(2010)
Science
, vol.328
, pp. 1566-1569
-
-
Najafi-Shoushtari, S.H.1
Kristo, F.2
Li, Y.3
Shioda, T.4
Cohen, D.E.5
Gerszten, R.E.6
Naar, A.M.7
-
131
-
-
79959845414
-
MICRORNAS 103 and 107 regulate insulin sensitivity
-
Trajkovski, M.; Hausser, J.; Soutschek, J.; Bhat, B.; Akin, A.; Zavolan, M.; Heim, M. H.; Stoffel, M. MicroRNAs 103 and 107 regulate insulin sensitivity. Nature, 2011, 474, 649-653
-
(2011)
Nature
, vol.474
, pp. 649-653
-
-
Trajkovski, M.1
Hausser, J.2
Soutschek, J.3
Bhat, B.4
Akin, A.5
Zavolan, M.6
Heim, M.H.7
Stoffel, M.8
-
132
-
-
80053481600
-
The Lin28/let-7 axis regulates glucose metabolism
-
Zhu, H.; Shyh-Chang, N.; Segre, A. V; Shinoda, G.; Shah, S. P.; Einhorn, W. S.; Takeuchi, A.; Engreitz, J. M.; Hagan, J. P.; Kharas, M. G.; Urbach, A.; Thornton, J. E.; Triboulet, R.; Gregory, R. I.; Altshuler, D.; Daley, G. Q. The Lin28/let-7 axis regulates glucose metabolism. Cell, 2011, 147, 81-94
-
(2011)
Cell
, vol.147
, pp. 81-94
-
-
Zhu, H.1
Shyh-Chang, N.2
Segre, A.V.3
Shinoda, G.4
Shah, S.P.5
Einhorn, W.S.6
Takeuchi, A.7
Engreitz, J.M.8
Hagan, J.P.9
Kharas, M.G.10
Urbach, A.11
Thornton, J.E.12
Triboulet, R.13
Gregory, R.I.14
Altshuler, D.15
Daley, G.Q.16
-
133
-
-
84855518254
-
Control of glucose homeostasis and insulin sensitivity by the let-7 family of MICRORNAS
-
Frost, R. J. A.; Olson, E. N. Control of glucose homeostasis and insulin sensitivity by the let-7 family of microRNAs. Proc. Natl. Acad. Sci. U.S.A., 2011, 108, 21075-21080
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 21075-21080
-
-
Frost, R.J.A.1
Olson, E.N.2
-
134
-
-
84860340270
-
A Cardiac microRNA governs systemic energy homeostasis by regulation of MED13
-
Grueter, C. E.; van Rooij, E.; Johnson, B. A.; DeLeon, S. M.; Sutherland, L. B.; Qi, X.; Gautron, L.; Elmquist, J. K.; Bassel-Duby, R.; Olson, E. N. A Cardiac microRNA governs systemic energy homeostasis by regulation of MED13. Cell, 2012, 149, 671-683
-
(2012)
Cell
, vol.149
, pp. 671-683
-
-
Grueter, C.E.1
Van Rooij, E.2
Johnson, B.A.3
Deleon, S.M.4
Sutherland, L.B.5
Qi, X.6
Gautron, L.7
Elmquist, J.K.8
Bassel-Duby, R.9
Olson, E.N.10
-
135
-
-
77956061393
-
MICRORNA-21 (MIR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)
-
Zhang, J.-G.; Wang, J.-J.; Zhao, F.; Liu, Q.; Jiang, K.; Yang, G.-H. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin. Chim. Acta., 2010, 411, 846-852
-
(2010)
Clin. Chim. Acta
, vol.411
, pp. 846-852
-
-
Zhang, J.-G.1
Wang, J.-J.2
Zhao, F.3
Liu, Q.4
Jiang, K.5
Yang, G.-H.6
-
136
-
-
84899103245
-
MICRORNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1 network in skeletal muscle
-
Mohamed, J. S.; Hajira, A.; Pardo, P. S.; Boriek, A. M. MicroRNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1 network in skeletal muscle. Diabetes, 2014, 63, 1546-1559
-
(2014)
Diabetes
, vol.63
, pp. 1546-1559
-
-
Mohamed, J.S.1
Hajira, A.2
Pardo, P.S.3
Boriek, A.M.4
-
137
-
-
84866546187
-
Control of mitochondrial metabolism and systemic energy homeostasis by MICRORNAS 378 and 378
-
Carrer, M.; Liu, N.; Grueter, C. E.; Williams, A. H.; Frisard, M. I.; Hulver, M. W.; Bassel-Duby, R.; Olson, E. N. Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378. Proc. Natl. Acad. Sci. U.S.A., 2012, 109, 15330-15335
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 15330-15335
-
-
Carrer, M.1
Liu, N.2
Grueter, C.E.3
Williams, A.H.4
Frisard, M.I.5
Hulver, M.W.6
Bassel-Duby, R.7
Olson, E.N.8
-
138
-
-
77950866408
-
MICRORNA-15b modulates cellular ATP levels and degenerates mitochondria via Arl2 in neonatal rat cardiac myocytes
-
Nishi, H.; Ono, K.; Iwanaga, Y.; Horie, T.; Nagao, K.; Takemura, G.; Kinoshita, M.; Kuwabara, Y.; Mori, R. T.; Hasegawa, K.; Kita, T.; Kimura, T. MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via Arl2 in neonatal rat cardiac myocytes. J. Biol. Chem., 2010, 285, 4920-4930
-
(2010)
J. Biol. Chem
, vol.285
, pp. 4920-4930
-
-
Nishi, H.1
Ono, K.2
Iwanaga, Y.3
Horie, T.4
Nagao, K.5
Takemura, G.6
Kinoshita, M.7
Kuwabara, Y.8
Mori, R.T.9
Hasegawa, K.10
Kita, T.11
Kimura, T.12
-
139
-
-
84895544208
-
MICRORNAS as regulators of mitochondrial function: Role in cancer suppression
-
Tomasetti, M.; Neuzil, J.; Dong, L. MicroRNAs as regulators of mitochondrial function: Role in cancer suppression. Biochim. Biophys. Acta., 2013, 1840, 1441-1453
-
(2013)
Biochim. Biophys. Acta
, vol.1840
, pp. 1441-1453
-
-
Tomasetti, M.1
Neuzil, J.2
Dong, L.3
-
140
-
-
58149379604
-
MICRORNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons
-
Aschrafi, A.; Schwechter, A. D.; Mameza, M. G.; Natera-Naranjo, O.; Gioio, A. E.; Kaplan, B. B. MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons. J. Neurosci., 2008, 28, 12581-12590
-
(2008)
J. Neurosci
, vol.28
, pp. 12581-12590
-
-
Aschrafi, A.1
Schwechter, A.D.2
Mameza, M.G.3
Natera-Naranjo, O.4
Gioio, A.E.5
Kaplan, B.B.6
-
141
-
-
84862279805
-
Nuclear MIRNA regulates the mitochondrial genome in the heart
-
Das, S.; Ferlito, M.; Kent, O. A.; Fox-Talbot, K.; Wang, R.; Liu, D.; Raghavachari, N.; Yang, Y.; Wheelan, S. J.; Murphy, E.; Steenbergen, C. Nuclear miRNA regulates the mitochondrial genome in the heart. Circ. Res., 2012, 110, 1596-1603
-
(2012)
Circ. Res
, vol.110
, pp. 1596-1603
-
-
Das, S.1
Ferlito, M.2
Kent, O.A.3
Fox-Talbot, K.4
Wang, R.5
Liu, D.6
Raghavachari, N.7
Yang, Y.8
Wheelan, S.J.9
Murphy, E.10
Steenbergen, C.11
-
142
-
-
84901020290
-
MIR-181c regulates the mitochondrial genome, bioenergetics, and propensity for heart failure in vivo
-
Das, S.; Bedja, D.; Campbell, N.; Dunkerly, B.; Chenna, V.; Maitra, A.; Steenbergen, C. miR-181c regulates the mitochondrial genome, bioenergetics, and propensity for heart failure in vivo. PLoS One, 2014, 9, e96820
-
(2014)
PLoS One
, vol.9
, pp. e96820
-
-
Das, S.1
Bedja, D.2
Campbell, N.3
Dunkerly, B.4
Chenna, V.5
Maitra, A.6
Steenbergen, C.7
-
143
-
-
84896137254
-
Effects of downregulation of microRNA-181a on H2O2-induced H9c2 Cell apoptosis via the mitochondrial apoptotic pathway
-
Wang, L.; Huang, H.; Fan, Y.; Kong, B.; Hu, H.; Hu, K.; Guo, J.; Mei, Y.; Liu, W. Effects of downregulation of microRNA-181a on H2O2-induced H9c2 Cell apoptosis via the mitochondrial apoptotic pathway. Oxid. Med. Cell. Longev., 2014, 2014, 960362
-
(2014)
Oxid. Med. Cell. Longev
, vol.2014
, pp. 960362
-
-
Wang, L.1
Huang, H.2
Fan, Y.3
Kong, B.4
Hu, H.5
Hu, K.6
Guo, J.7
Mei, Y.8
Liu, W.9
-
144
-
-
84901423103
-
MicrorNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes
-
Karbiener, M.; Pisani, D.; Frontini, A.; Oberreiter, L.; Lang, E.; Vegiopoulos, A.; Mossenbock, K.; Bernhardt, G.; Mayr, T.; Hildner, F.; Grillari, J.; Ailhaud, G.; Herzig, S.; Cinti, S.; Amri, E.; Scheideler, M. MicroRNA-26 family Is required for human adipogenesis and drives characteristics of brown adipocytes. Stem Cells, 2014, 32, 1578-1590
-
(2014)
Stem Cells
, vol.32
, pp. 1578-1590
-
-
Karbiener, M.1
Pisani, D.2
Frontini, A.3
Oberreiter, L.4
Lang, E.5
Vegiopoulos, A.6
Mossenbock, K.7
Bernhardt, G.8
Mayr, T.9
Hildner, F.10
Grillari, J.11
Ailhaud, G.12
Herzig, S.13
Cinti, S.14
Amri, E.15
Scheideler, M.16
-
145
-
-
84889025854
-
MICRORNA-27 (MIR-27) targets prohibitin and impairs adipocyte differentiation and mitochondrial function in human adipose-derived stem cells
-
Kang, T.; Lu, W.; Xu, W.; Anderson, L.; Bacanamwo, M.; Thompson, W.; Chen, Y. E.; Liu, D. MicroRNA-27 (miR-27) targets prohibitin and impairs adipocyte differentiation and mitochondrial function in human adipose-derived stem cells. J. Biol. Chem., 2013, 288, 34394-34402
-
(2013)
J. Biol. Chem
, vol.288
, pp. 34394-34402
-
-
Kang, T.1
Lu, W.2
Xu, W.3
Anderson, L.4
Bacanamwo, M.5
Thompson, W.6
Chen, Y.E.7
Liu, D.8
-
146
-
-
84868627011
-
MICRORNA regulation of autophagy
-
Frankel, L. B.; Lund, A. H. MicroRNA regulation of autophagy. Carcinogenesis, 2012, 33, 2018-2025
-
(2012)
Carcinogenesis
, vol.33
, pp. 2018-2025
-
-
Frankel, L.B.1
Lund, A.H.2
-
147
-
-
84881140099
-
MIR-761 regulates the mitochondrial network by targeting mitochondrial fission factor
-
Long, B.; Wang, K.; Li, N.; Murtaza, I.; Xiao, J.-Y.; Fan, Y.-Y.; Liu, C.-Y.; Li, W.-H.; Cheng, Z.; Li, P. miR-761 regulates the mitochondrial network by targeting mitochondrial fission factor. Free Radic. Biol. Med., 2013, 65C, 371-379
-
(2013)
Free Radic. Biol. Med
, vol.65 C
, pp. 371-379
-
-
Long, B.1
Wang, K.2
Li, N.3
Murtaza, I.4
Xiao, J.-Y.5
Fan, Y.-Y.6
Liu, C.-Y.7
Li, W.-H.8
Cheng, Z.9
Li, P.10
-
148
-
-
76749157966
-
MIR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway
-
Li, J.; Donath, S.; Li, Y.; Qin, D.; Prabhakar, B. S.; Li, P. miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway. PLoS Genet., 2010, 6, e1000795
-
(2010)
PLoS Genet
, vol.6
, pp. e1000795
-
-
Li, J.1
Donath, S.2
Li, Y.3
Qin, D.4
Prabhakar, B.S.5
Li, P.6
-
149
-
-
84899148319
-
Mitofusin 1 is negatively regulated by MICRORNA 140 in cardiomyocyte apoptosis
-
Li, J.; Li, Y.; Jiao, J.; Wang, J.; Li, Y.; Qin, D.; Li, P. Mitofusin 1 Is negatively regulated by microRNA 140 in cardiomyocyte apoptosis. Mol. Cell. Biol., 2014, 34, 1788-1799
-
(2014)
Mol. Cell. Biol
, vol.34
, pp. 1788-1799
-
-
Li, J.1
Li, Y.2
Jiao, J.3
Wang, J.4
Li, Y.5
Qin, D.6
Li, P.7
-
150
-
-
84860298409
-
MIR-484 regulates mitochondrial network through targeting fis1
-
Wang, K.; Long, B.; Jiao, J.-Q.; Wang, J.-X.; Liu, J.-P.; Li, Q.; Li, P.-F. miR-484 regulates mitochondrial network through targeting fis1. Nat. Commun., 2012, 3, 781
-
(2012)
Nat. Commun
, vol.3
, pp. 781
-
-
Wang, K.1
Long, B.2
Jiao, J.-Q.3
Wang, J.-X.4
Liu, J.-P.5
Li, Q.6
Li, P.-F.7
-
151
-
-
78650856185
-
Mitochondrial dynamics in diabetes
-
Yoon, Y.; Galloway, C. A.; Jhun, B. S.; Yu, T. Mitochondrial dynamics in diabetes. Antioxid. Redox Signal., 2011, 14, 439-457
-
(2011)
Antioxid. Redox Signal
, vol.14
, pp. 439-457
-
-
Yoon, Y.1
Galloway, C.A.2
Jhun, B.S.3
Yu, T.4
-
152
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D.; Weinberg, R. A. The hallmarks of cancer. Cell, 2000, 100, 57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
153
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D.; Weinberg, R. A. Hallmarks of cancer: The next generation. Cell, 2011, 144, 646-674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
154
-
-
0001221508
-
On Respiratory impairment in cancer cells
-
Warburg, O. On Respiratory impairment in cancer cells. Science, 1956, 124, 269-270
-
(1956)
Science
, vol.124
, pp. 269-270
-
-
Warburg, O.1
-
155
-
-
84867249149
-
Energy metabolism of cancer: Glycolysis versus oxidative phosphorylation (Review)
-
Zheng, J. Energy metabolism of cancer: glycolysis versus oxidative phosphorylation (Review). Oncol. Lett., 2012, 4, 1151-1157
-
(2012)
Oncol. Lett
, vol.4
, pp. 1151-1157
-
-
Zheng, J.1
-
156
-
-
80051778368
-
Mitochondria in cancer: At the crossroads of life and death
-
Fogg, V. C.; Lanning, N. J.; Mackeigan, J. P. Mitochondria in cancer: at the crossroads of life and death. Chin. J. Cancer, 2011, 30, 526-539
-
(2011)
Chin. J. Cancer
, vol.30
, pp. 526-539
-
-
Fogg, V.C.1
Lanning, N.J.2
Mackeigan, J.P.3
-
157
-
-
84866450306
-
MIR-124, MIR-137 and MIR-340 regulate colorectal cancer growth via inhibition of the warburg effect
-
Sun, Y.; Zhao, X.; Zhou, Y.; Hu, Y. miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the warburg effect. Oncol. Rep., 2012, 28, 1346-1352
-
(2012)
Oncol. Rep
, vol.28
, pp. 1346-1352
-
-
Sun, Y.1
Zhao, X.2
Zhou, Y.3
Hu, Y.4
-
158
-
-
78650126775
-
Pyruvate Kinase M2 is a target of the tumor-suppressive MICRORNA-326 and regulates the survival of glioma Cells
-
Kefas, B.; Comeau, L.; Erdle, N.; Montgomery, E.; Amos, S.; Purow, B. Pyruvate Kinase M2 Is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma Cells. Neuro Oncol., 2010, 12, 1102-1112
-
(2010)
Neuro Oncol
, vol.12
, pp. 1102-1112
-
-
Kefas, B.1
Comeau, L.2
Erdle, N.3
Montgomery, E.4
Amos, S.5
Purow, B.6
-
159
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive mmetabolic response to hypoxia
-
Zhang, H.; Bosch-Marce, M.; Shimoda, L. A.; Tan, Y. S.; Baek, J. H.; Wesley, J. B.; Gonzalez, F. J.; Semenza, G. L. Mitochondrial autophagy is an HIF-1-dependent adaptive mmetabolic response to hypoxia. J. Biol. Chem., 2008, 283, 10892-10903.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
|