메뉴 건너뛰기




Volumn 7, Issue 5, 2012, Pages

Mitochondrial structure, function and dynamics are temporally controlled by c-Myc

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; MYC PROTEIN; ONCOPROTEIN;

EID: 84861302910     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037699     Document Type: Article
Times cited : (102)

References (72)
  • 1
    • 0033551374 scopus 로고    scopus 로고
    • MYC oncogenes and human neoplastic disease
    • Nesbit CE, Tersak JM, Prochownik EV, (1999) MYC oncogenes and human neoplastic disease. Oncogene 18: 3004-3016.
    • (1999) Oncogene , vol.18 , pp. 3004-3016
    • Nesbit, C.E.1    Tersak, J.M.2    Prochownik, E.V.3
  • 2
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ, (2008) Reflecting on 25 years with MYC. Nat Rev Cancer 8: 976-990.
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 3
    • 53149109725 scopus 로고    scopus 로고
    • c-Myc: linking transformation and genomic instability
    • Prochownik EV, (2008) c-Myc: linking transformation and genomic instability. Curr Mol Med 8: 446-458.
    • (2008) Curr Mol Med , vol.8 , pp. 446-458
    • Prochownik, E.V.1
  • 5
    • 78650246896 scopus 로고    scopus 로고
    • Inhibition of Myc effectively targets KRAS mutation-positive lung cancer expressing high levels of Myc
    • Fukazawa T, Maeda Y, Matsuoka J, Yamatsuji T, Shigemitsu K, et al. (2010) Inhibition of Myc effectively targets KRAS mutation-positive lung cancer expressing high levels of Myc. Anticancer Res 30: 4193-4200.
    • (2010) Anticancer Res , vol.30 , pp. 4193-4200
    • Fukazawa, T.1    Maeda, Y.2    Matsuoka, J.3    Yamatsuji, T.4    Shigemitsu, K.5
  • 6
    • 70350241382 scopus 로고    scopus 로고
    • c-Myc and eIF4F constitute a feedforward loop that regulates cell growth: implications for anticancer therapy
    • Lin CJ, Malina A, Pelletier J, (2009) c-Myc and eIF4F constitute a feedforward loop that regulates cell growth: implications for anticancer therapy. Cancer Res 69: 7491-7494.
    • (2009) Cancer Res , vol.69 , pp. 7491-7494
    • Lin, C.J.1    Malina, A.2    Pelletier, J.3
  • 7
    • 33645109124 scopus 로고    scopus 로고
    • c-myc expression: keep the noise down!
    • Chung HJ, Levens D, (2005) c-myc expression: keep the noise down! Mol Cells 20: 157-166.
    • (2005) Mol Cells , vol.20 , pp. 157-166
    • Chung, H.J.1    Levens, D.2
  • 8
    • 14744284578 scopus 로고    scopus 로고
    • c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
    • Grandori C, Gomez-Roman N, Felton-Edkins ZA, Ngouenet C, Galloway DA, et al. (2005) c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat Cell Biol 7: 311-318.
    • (2005) Nat Cell Biol , vol.7 , pp. 311-318
    • Grandori, C.1    Gomez-Roman, N.2    Felton-Edkins, Z.A.3    Ngouenet, C.4    Galloway, D.A.5
  • 9
    • 0347721764 scopus 로고    scopus 로고
    • Direct activation of RNA polymerase III transcription by c-Myc
    • Gomez-Roman N, Grandori C, Eisenman RN, White RJ, (2003) Direct activation of RNA polymerase III transcription by c-Myc. Nature 421: 290-294.
    • (2003) Nature , vol.421 , pp. 290-294
    • Gomez-Roman, N.1    Grandori, C.2    Eisenman, R.N.3    White, R.J.4
  • 10
    • 0038492517 scopus 로고    scopus 로고
    • A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells
    • Li Z, Van Calcar S, Qu C, Cavenee WK, Zhang MQ, et al. (2003) A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci U S A 100: 8164-8169.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8164-8169
    • Li, Z.1    Van Calcar, S.2    Qu, C.3    Cavenee, W.K.4    Zhang, M.Q.5
  • 11
    • 33845187907 scopus 로고    scopus 로고
    • Global mapping of c-Myc binding sites and target gene networks in human B cells
    • Zeller KI, Zhao X, Lee CW, Chiu KP, Yao F, et al. (2006) Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci U S A 103: 17834-17839.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17834-17839
    • Zeller, K.I.1    Zhao, X.2    Lee, C.W.3    Chiu, K.P.4    Yao, F.5
  • 12
    • 21744442902 scopus 로고    scopus 로고
    • Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis
    • Li F, Wang Y, Zeller KI, Potter JJ, Wonsey DR, et al. (2005) Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol Cell Biol 25: 6225-6234.
    • (2005) Mol Cell Biol , vol.25 , pp. 6225-6234
    • Li, F.1    Wang, Y.2    Zeller, K.I.3    Potter, J.J.4    Wonsey, D.R.5
  • 13
    • 46349099384 scopus 로고    scopus 로고
    • Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo
    • Kim J, Lee JH, Iyer VR, (2008) Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo. PLoS One 3: e1798.
    • (2008) PLoS One , vol.3
    • Kim, J.1    Lee, J.H.2    Iyer, V.R.3
  • 14
    • 67650417891 scopus 로고    scopus 로고
    • c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry
    • Morrish F, Isern N, Sadilek M, Jeffrey M, Hockenbery DM, (2009) c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry. Oncogene 28: 2485-2491.
    • (2009) Oncogene , vol.28 , pp. 2485-2491
    • Morrish, F.1    Isern, N.2    Sadilek, M.3    Jeffrey, M.4    Hockenbery, D.M.5
  • 15
    • 34247614521 scopus 로고    scopus 로고
    • HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
    • Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, et al. (2007) HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 11: 407-420.
    • (2007) Cancer Cell , vol.11 , pp. 407-420
    • Zhang, H.1    Gao, P.2    Fukuda, R.3    Kumar, G.4    Krishnamachary, B.5
  • 16
    • 70350728803 scopus 로고    scopus 로고
    • MYC-induced cancer cell energy metabolism and therapeutic opportunities
    • Dang CV, Le A, Gao P, (2009) MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin Cancer Res 15: 6479-6483.
    • (2009) Clin Cancer Res , vol.15 , pp. 6479-6483
    • Dang, C.V.1    Le, A.2    Gao, P.3
  • 18
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB, (2009) Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324: 1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 19
    • 77951839683 scopus 로고    scopus 로고
    • Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice
    • Ahuja P, Zhao P, Angelis E, Ruan H, Korge P, et al. (2010) Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. J Clin Invest 120: 1494-1505.
    • (2010) J Clin Invest , vol.120 , pp. 1494-1505
    • Ahuja, P.1    Zhao, P.2    Angelis, E.3    Ruan, H.4    Korge, P.5
  • 20
    • 38449092832 scopus 로고    scopus 로고
    • Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators
    • discussion 63-69
    • Spiegelman BM, (2007) Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators. Novartis Found Symp 287: 60-63; discussion 63-69.
    • (2007) Novartis Found Symp , vol.287 , pp. 60-63
    • Spiegelman, B.M.1
  • 21
    • 0032504568 scopus 로고    scopus 로고
    • The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy
    • Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, et al. (1998) The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim Biophys Acta 1366: 177-196.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 177-196
    • Lemasters, J.J.1    Nieminen, A.L.2    Qian, T.3    Trost, L.C.4    Elmore, S.P.5
  • 22
    • 77951096150 scopus 로고    scopus 로고
    • Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
    • Chen H, Chan DC, (2009) Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases. Hum Mol Genet 18: R169-176.
    • (2009) Hum Mol Genet , vol.18
    • Chen, H.1    Chan, D.C.2
  • 23
    • 77955287381 scopus 로고    scopus 로고
    • Physiological functions of mitochondrial fusion
    • Chen H, Chan DC, (2010) Physiological functions of mitochondrial fusion. Ann N Y Acad Sci 1201: 21-25.
    • (2010) Ann N Y Acad Sci , vol.1201 , pp. 21-25
    • Chen, H.1    Chan, D.C.2
  • 24
    • 27744491193 scopus 로고    scopus 로고
    • Emerging functions of mammalian mitochondrial fusion and fission
    • Chen H, Chan DC, (2005) Emerging functions of mammalian mitochondrial fusion and fission. Hum Mol Genet 14 Spec No. 2: R283-289.
    • (2005) Hum Mol Genet , vol.14 , Issue.2
    • Chen, H.1    Chan, D.C.2
  • 25
    • 22544451586 scopus 로고    scopus 로고
    • Disruption of fusion results in mitochondrial heterogeneity and dysfunction
    • Chen H, Chomyn A, Chan DC, (2005) Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J Biol Chem 280: 26185-26192.
    • (2005) J Biol Chem , vol.280 , pp. 26185-26192
    • Chen, H.1    Chomyn, A.2    Chan, D.C.3
  • 26
    • 33746106937 scopus 로고    scopus 로고
    • MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species
    • Ray S, Atkuri KR, Deb-Basu D, Adler AS, Chang HY, et al. (2006) MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species. Cancer Res 66: 6598-6605.
    • (2006) Cancer Res , vol.66 , pp. 6598-6605
    • Ray, S.1    Atkuri, K.R.2    Deb-Basu, D.3    Adler, A.S.4    Chang, H.Y.5
  • 27
    • 0036285034 scopus 로고    scopus 로고
    • c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability
    • Vafa O, Wade M, Kern S, Beeche M, Pandita TK, et al. (2002) c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol Cell 9: 1031-1044.
    • (2002) Mol Cell , vol.9 , pp. 1031-1044
    • Vafa, O.1    Wade, M.2    Kern, S.3    Beeche, M.4    Pandita, T.K.5
  • 29
    • 77955298543 scopus 로고    scopus 로고
    • Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1
    • Chang CR, Blackstone C, (2010) Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1. Ann N Y Acad Sci 1201: 34-39.
    • (2010) Ann N Y Acad Sci , vol.1201 , pp. 34-39
    • Chang, C.R.1    Blackstone, C.2
  • 30
    • 77953713350 scopus 로고    scopus 로고
    • In quiescence of fission yeast, autophagy and the proteasome collaborate for mitochondrial maintenance and longevity
    • Takeda K, Yanagida M, (2010) In quiescence of fission yeast, autophagy and the proteasome collaborate for mitochondrial maintenance and longevity. Autophagy 6.
    • (2010) Autophagy , vol.6
    • Takeda, K.1    Yanagida, M.2
  • 32
  • 33
    • 0027528769 scopus 로고
    • A cell culture model system for genetic analyses of the cell cycle by targeted homologous recombination
    • Prouty SM, Hanson KD, Boyle AL, Brown JR, Shichiri M, et al. (1993) A cell culture model system for genetic analyses of the cell cycle by targeted homologous recombination. Oncogene 8: 899-907.
    • (1993) Oncogene , vol.8 , pp. 899-907
    • Prouty, S.M.1    Hanson, K.D.2    Boyle, A.L.3    Brown, J.R.4    Shichiri, M.5
  • 34
    • 0030849451 scopus 로고    scopus 로고
    • Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination
    • Mateyak MK, Obaya AJ, Adachi S, Sedivy JM, (1997) Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination. Cell Growth Differ 8: 1039-1048.
    • (1997) Cell Growth Differ , vol.8 , pp. 1039-1048
    • Mateyak, M.K.1    Obaya, A.J.2    Adachi, S.3    Sedivy, J.M.4
  • 35
    • 0024396222 scopus 로고
    • Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells
    • Eilers M, Picard D, Yamamoto KR, Bishop JM, (1989) Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature 340: 66-68.
    • (1989) Nature , vol.340 , pp. 66-68
    • Eilers, M.1    Picard, D.2    Yamamoto, K.R.3    Bishop, J.M.4
  • 36
    • 0029002136 scopus 로고
    • A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
    • Littlewood TD, Hancock DC, Danielian PS, Parker MG, Evan GI, (1995) A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res 23: 1686-1690.
    • (1995) Nucleic Acids Res , vol.23 , pp. 1686-1690
    • Littlewood, T.D.1    Hancock, D.C.2    Danielian, P.S.3    Parker, M.G.4    Evan, G.I.5
  • 37
    • 0033179331 scopus 로고    scopus 로고
    • The use of chloromethyl-X-rosamine (Mitotracker red) to measure loss of mitochondrial membrane potential in apoptotic cells is incompatible with cell fixation
    • Gilmore K, Wilson M, (1999) The use of chloromethyl-X-rosamine (Mitotracker red) to measure loss of mitochondrial membrane potential in apoptotic cells is incompatible with cell fixation. Cytometry 36: 355-358.
    • (1999) Cytometry , vol.36 , pp. 355-358
    • Gilmore, K.1    Wilson, M.2
  • 38
    • 0029966796 scopus 로고    scopus 로고
    • Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis
    • Macho A, Decaudin D, Castedo M, Hirsch T, Susin SA, et al. (1996) Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry 25: 333-340.
    • (1996) Cytometry , vol.25 , pp. 333-340
    • Macho, A.1    Decaudin, D.2    Castedo, M.3    Hirsch, T.4    Susin, S.A.5
  • 39
    • 77955273254 scopus 로고    scopus 로고
    • Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics
    • Sauvanet C, Duvezin-Caubet S, di Rago JP, Rojo M, (2010) Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics. Semin Cell Dev Biol 21: 558-565.
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 558-565
    • Sauvanet, C.1    Duvezin-Caubet, S.2    di Rago, J.P.3    Rojo, M.4
  • 41
    • 0025806764 scopus 로고
    • Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1
    • Smiley ST, Reers M, Mottola-Hartshorn C, Lin M, Chen A, et al. (1991) Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A 88: 3671-3675.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 3671-3675
    • Smiley, S.T.1    Reers, M.2    Mottola-Hartshorn, C.3    Lin, M.4    Chen, A.5
  • 42
    • 2942635457 scopus 로고    scopus 로고
    • Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity
    • Perl A, Gergely P Jr, Nagy G, Koncz A, Banki K, (2004) Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity. Trends Immunol 25: 360-367.
    • (2004) Trends Immunol , vol.25 , pp. 360-367
    • Perl, A.1    Gergely Jr., P.2    Nagy, G.3    Koncz, A.4    Banki, K.5
  • 43
    • 78149431906 scopus 로고    scopus 로고
    • Point Mutations in c-Myc Uncouple Neoplastic Transformation from Multiple Other Phenotypes in Rat Fibroblasts
    • Graves JA, Rothermund K, Wang T, Qian W, Van Houten B, et al. (2010) Point Mutations in c-Myc Uncouple Neoplastic Transformation from Multiple Other Phenotypes in Rat Fibroblasts. PLoS ONE 5: e13717.
    • (2010) PLoS ONE , vol.5
    • Graves, J.A.1    Rothermund, K.2    Wang, T.3    Qian, W.4    Van Houten, B.5
  • 44
    • 33846317064 scopus 로고    scopus 로고
    • Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
    • Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, et al. (2007) Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am J Physiol Cell Physiol 292: C125-136.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Wu, M.1    Neilson, A.2    Swift, A.L.3    Moran, R.4    Tamagnine, J.5
  • 45
    • 35548982628 scopus 로고    scopus 로고
    • Bioenergetics of mitochondria in cultured neurons and their role in glutamate excitotoxicity
    • Nicholls DG, Johnson-Cadwell L, Vesce S, Jekabsons M, Yadava N, (2007) Bioenergetics of mitochondria in cultured neurons and their role in glutamate excitotoxicity. J Neurosci Res 85: 3206-3212.
    • (2007) J Neurosci Res , vol.85 , pp. 3206-3212
    • Nicholls, D.G.1    Johnson-Cadwell, L.2    Vesce, S.3    Jekabsons, M.4    Yadava, N.5
  • 46
    • 34447122557 scopus 로고    scopus 로고
    • Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone
    • Yadava N, Nicholls DG, (2007) Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone. J Neurosci 27: 7310-7317.
    • (2007) J Neurosci , vol.27 , pp. 7310-7317
    • Yadava, N.1    Nicholls, D.G.2
  • 47
    • 77949634569 scopus 로고    scopus 로고
    • Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject
    • Lenaz G, Genova ML, (2010) Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject. Antioxid Redox Signal 12: 961-1008.
    • (2010) Antioxid Redox Signal , vol.12 , pp. 961-1008
    • Lenaz, G.1    Genova, M.L.2
  • 48
    • 77956902886 scopus 로고    scopus 로고
    • Evidence for physical association of mitochondrial fatty acid oxidation and oxidative phosphorylation complexes
    • Wang Y, Mohsen AW, Mihalik SJ, Goetzman ES, Vockley J, (2010) Evidence for physical association of mitochondrial fatty acid oxidation and oxidative phosphorylation complexes. J Biol Chem 285: 29834-29841.
    • (2010) J Biol Chem , vol.285 , pp. 29834-29841
    • Wang, Y.1    Mohsen, A.W.2    Mihalik, S.J.3    Goetzman, E.S.4    Vockley, J.5
  • 49
    • 41949123425 scopus 로고    scopus 로고
    • Dimer ribbons of ATP synthase shape the inner mitochondrial membrane
    • Strauss M, Hofhaus G, Schroder RR, Kuhlbrandt W, (2008) Dimer ribbons of ATP synthase shape the inner mitochondrial membrane. Embo J 27: 1154-1160.
    • (2008) Embo J , vol.27 , pp. 1154-1160
    • Strauss, M.1    Hofhaus, G.2    Schroder, R.R.3    Kuhlbrandt, W.4
  • 51
    • 0029075321 scopus 로고
    • Topographical organization of cytochrome b in the yeast mitochondrial membrane determined by fluorescence studies with N-cyclohexyl-N′-[4-(dimethylamino)naphthyl]carbodiimide
    • Wang Y, Howton MM, Beattie DS, (1995) Topographical organization of cytochrome b in the yeast mitochondrial membrane determined by fluorescence studies with N-cyclohexyl-N′-[4-(dimethylamino)naphthyl]carbodiimide. Biochemistry 34: 7476-7482.
    • (1995) Biochemistry , vol.34 , pp. 7476-7482
    • Wang, Y.1    Howton, M.M.2    Beattie, D.S.3
  • 52
    • 34547138661 scopus 로고    scopus 로고
    • High resolution clear native electrophoresis for in-gel functional assays and fluorescence studies of membrane protein complexes
    • Wittig I, Karas M, Schagger H, (2007) High resolution clear native electrophoresis for in-gel functional assays and fluorescence studies of membrane protein complexes. Molecular & cellular proteomics: MCP 6: 1215-1225.
    • (2007) Molecular & Cellular Proteomics: MCP , vol.6 , pp. 1215-1225
    • Wittig, I.1    Karas, M.2    Schagger, H.3
  • 53
    • 0036906665 scopus 로고    scopus 로고
    • Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins
    • Legros F, Lombes A, Frachon P, Rojo M, (2002) Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol Biol Cell 13: 4343-4354.
    • (2002) Mol Biol Cell , vol.13 , pp. 4343-4354
    • Legros, F.1    Lombes, A.2    Frachon, P.3    Rojo, M.4
  • 54
    • 0037455575 scopus 로고    scopus 로고
    • Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
    • Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, et al. (2003) Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 160: 189-200.
    • (2003) J Cell Biol , vol.160 , pp. 189-200
    • Chen, H.1    Detmer, S.A.2    Ewald, A.J.3    Griffin, E.E.4    Fraser, S.E.5
  • 55
    • 3843075121 scopus 로고    scopus 로고
    • Structural basis of mitochondrial tethering by mitofusin complexes
    • Koshiba T, Detmer SA, Kaiser JT, Chen H, McCaffery JM, et al. (2004) Structural basis of mitochondrial tethering by mitofusin complexes. Science 305: 858-862.
    • (2004) Science , vol.305 , pp. 858-862
    • Koshiba, T.1    Detmer, S.A.2    Kaiser, J.T.3    Chen, H.4    McCaffery, J.M.5
  • 56
    • 0037424239 scopus 로고    scopus 로고
    • Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
    • Olichon A, Baricault L, Gas N, Guillou E, Valette A, et al. (2003) Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem 278: 7743-7746.
    • (2003) J Biol Chem , vol.278 , pp. 7743-7746
    • Olichon, A.1    Baricault, L.2    Gas, N.3    Guillou, E.4    Valette, A.5
  • 57
    • 0035166814 scopus 로고    scopus 로고
    • Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
    • Smirnova E, Griparic L, Shurland DL, van der Bliek AM, (2001) Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol Biol Cell 12: 2245-2256.
    • (2001) Mol Biol Cell , vol.12 , pp. 2245-2256
    • Smirnova, E.1    Griparic, L.2    Shurland, D.L.3    van der Bliek, A.M.4
  • 58
    • 0043092647 scopus 로고    scopus 로고
    • The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
    • Yoon Y, Krueger EW, Oswald BJ, McNiven MA, (2003) The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Mol Cell Biol 23: 5409-5420.
    • (2003) Mol Cell Biol , vol.23 , pp. 5409-5420
    • Yoon, Y.1    Krueger, E.W.2    Oswald, B.J.3    McNiven, M.A.4
  • 60
    • 79953705886 scopus 로고    scopus 로고
    • Choosing between glycolysis and oxidative phosphorylation: a tumor's dilemma?
    • Jose C, Bellance N, Rossignol R, (2011) Choosing between glycolysis and oxidative phosphorylation: a tumor's dilemma? Biochim Biophys Acta 1807: 552-561.
    • (2011) Biochim Biophys Acta , vol.1807 , pp. 552-561
    • Jose, C.1    Bellance, N.2    Rossignol, R.3
  • 61
    • 1542286155 scopus 로고    scopus 로고
    • Intimate contacts of mitochondria with nuclear envelope as a potential energy gateway for nucleo-cytoplasmic mRNA transport
    • Prachar J, (2003) Intimate contacts of mitochondria with nuclear envelope as a potential energy gateway for nucleo-cytoplasmic mRNA transport. General physiology and biophysics 22: 525-534.
    • (2003) General Physiology and Biophysics , vol.22 , pp. 525-534
    • Prachar, J.1
  • 62
    • 0038783254 scopus 로고    scopus 로고
    • Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells
    • Santel A, Frank S, Gaume B, Herrler M, Youle RJ, et al. (2003) Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells. J Cell Sci 116: 2763-2774.
    • (2003) J Cell Sci , vol.116 , pp. 2763-2774
    • Santel, A.1    Frank, S.2    Gaume, B.3    Herrler, M.4    Youle, R.J.5
  • 63
    • 77953811727 scopus 로고    scopus 로고
    • Structure-function relationships in feedback regulation of energy fluxes in vivo in health and disease: mitochondrial interactosome
    • Saks V, Guzun R, Timohhina N, Tepp K, Varikmaa M, et al. (2010) Structure-function relationships in feedback regulation of energy fluxes in vivo in health and disease: mitochondrial interactosome. Biochim Biophys Acta 1797: 678-697.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 678-697
    • Saks, V.1    Guzun, R.2    Timohhina, N.3    Tepp, K.4    Varikmaa, M.5
  • 64
    • 79952291364 scopus 로고    scopus 로고
    • Molecular mechanisms and physiologic functions of mitochondrial dynamics
    • Otera H, Mihara K, (2011) Molecular mechanisms and physiologic functions of mitochondrial dynamics. J Biochem 149: 241-251.
    • (2011) J Biochem , vol.149 , pp. 241-251
    • Otera, H.1    Mihara, K.2
  • 65
    • 43549098260 scopus 로고    scopus 로고
    • The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry
    • Morrish F, Neretti N, Sedivy JM, Hockenbery DM, (2008) The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry. Cell Cycle 7: 1054-1066.
    • (2008) Cell Cycle , vol.7 , pp. 1054-1066
    • Morrish, F.1    Neretti, N.2    Sedivy, J.M.3    Hockenbery, D.M.4
  • 66
    • 0036319021 scopus 로고    scopus 로고
    • Generation of reactive oxygen species by the mitochondrial electron transport chain
    • Liu Y, Fiskum G, Schubert D, (2002) Generation of reactive oxygen species by the mitochondrial electron transport chain. J Neurochem 80: 780-787.
    • (2002) J Neurochem , vol.80 , pp. 780-787
    • Liu, Y.1    Fiskum, G.2    Schubert, D.3
  • 67
    • 40449117017 scopus 로고    scopus 로고
    • Transformation, genomic instability and senescence mediated by platelet/megakaryocyte glycoprotein Ibalpha
    • Li Y, Lu J, Cohen D, Prochownik EV, (2008) Transformation, genomic instability and senescence mediated by platelet/megakaryocyte glycoprotein Ibalpha. Oncogene 27: 1599-1609.
    • (2008) Oncogene , vol.27 , pp. 1599-1609
    • Li, Y.1    Lu, J.2    Cohen, D.3    Prochownik, E.V.4
  • 68
    • 0030878395 scopus 로고    scopus 로고
    • Distinct roles for MAX protein isoforms in proliferation and apoptosis
    • Zhang H, Fan S, Prochownik EV, (1997) Distinct roles for MAX protein isoforms in proliferation and apoptosis. J Biol Chem 272: 17416-17424.
    • (1997) J Biol Chem , vol.272 , pp. 17416-17424
    • Zhang, H.1    Fan, S.2    Prochownik, E.V.3
  • 69
    • 61549104463 scopus 로고    scopus 로고
    • Type I epithelial cells are the main target of whole-body hypoxic preconditioning in the lung
    • Zhang SX, Miller JJ, Stolz DB, Serpero LD, Zhao W, et al. (2009) Type I epithelial cells are the main target of whole-body hypoxic preconditioning in the lung. Am J Respir Cell Mol Biol 40: 332-339.
    • (2009) Am J Respir Cell Mol Biol , vol.40 , pp. 332-339
    • Zhang, S.X.1    Miller, J.J.2    Stolz, D.B.3    Serpero, L.D.4    Zhao, W.5
  • 70
    • 80053424147 scopus 로고    scopus 로고
    • Quantifying spatial correlations of fluorescent markers using enhanced background reduction with protein proximity index and correlation coefficient estimations
    • Zinchuk V, Wu Y, Grossenbacher-Zinchuk O, Stefani E, (2011) Quantifying spatial correlations of fluorescent markers using enhanced background reduction with protein proximity index and correlation coefficient estimations. Nat Protoc 6: 1554-1567.
    • (2011) Nat Protoc , vol.6 , pp. 1554-1567
    • Zinchuk, V.1    Wu, Y.2    Grossenbacher-Zinchuk, O.3    Stefani, E.4
  • 72
    • 65249185741 scopus 로고    scopus 로고
    • Regulation of Reactive Oxygen Species Homeostasis by Peroxiredoxins and c-Myc
    • Graves JA, Metukuri M, Scott D, Rothermund K, Prochownik EV, (2009) Regulation of Reactive Oxygen Species Homeostasis by Peroxiredoxins and c-Myc. J Biol Chem 284: 6520-6529.
    • (2009) J Biol Chem , vol.284 , pp. 6520-6529
    • Graves, J.A.1    Metukuri, M.2    Scott, D.3    Rothermund, K.4    Prochownik, E.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.