Regeneration of Peroxiredoxins by p53-Regulated Sestrins, Homologs of Bacterial AhpD

Science

Volumn 304, Issue 5670, 2004, Pages 596-600

  Budanov, Andrei V ^a,b   Sablina, Anna A ^a,c   Feinstein, Elena ^d   Koonin, Eugene V ^e   Chumakov, Peter M ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^c Cancer Research Center   (Russian Federation)

^d QBI Enterprises Ltd   (Israel)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; BACTERIA; OXIDATION; PEROXIDES; PROTEINS; REDOX REACTIONS;

ANTIOXIDANT DEFENSE; PEROXIREDIXINS;

ENZYME KINETICS;

ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEIN; CYSTEINE SULFINYL REDUCTASE DERIVATIVE; DISULFIDE; HYDROGEN PEROXIDE; OXIDOREDUCTASE; PEROXIDE; PEROXIREDOXIN; PROTEIN AHPD; PROTEIN P53; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SESTRIN; SESTRIN 2; UNCLASSIFIED DRUG;

MEDICINE;

ANTIOXIDANT ACTIVITY; ARTICLE; CATALYSIS; ENZYME METABOLISM; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; HEAT-SHOCK PROTEINS; HUMANS; HYDROGEN PEROXIDE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; OXIDATION-REDUCTION; OXIDOREDUCTASES; PEROXIDASES; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

BACTERIA (MICROORGANISMS);

EID: 2142815107     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1095569     Document Type: Article

References (33)

1. T. Finkel, Curr. Opin. Cell Biol. 15, 247 (2003).
2. Z. A. Wood, E. Schroder, J. Robin Harris, L. B. Poole, Trends Biochem. Sci. 28, 32 (2003).
3. L. C. Seaver, J. A. Imlay, J. Bacteriol. 183, 7173 (2001).
4. L. Chen, Q. W. Xie, C. Nathan, Mol. Cell 1, 795 (1998).
5. R. Bryk, P. Griffin, C. Nathan, Nature 407, 211 (2000).
6. C. M. Wong, Y. Zhou, R. W. Ng, H. F. Kung Hf, D. Y. Jin, J. Biol. Chem. 277, 5385 (2002).
7. S. D. Barr, L. Gedamu, J. Biol. Chem. 278, 10816 (2003).
8. Z. A. Wood, L. B. Poole, P. A. Karplus, Science 300, 650 (2003).
9. T. Rabilloud et al., J. Biol. Chem. 277, 19396 (2002).
10. K. S. Yang et al., J. Biol. Chem. 277, 38029 (2002).
11. H. Z. Chae, S. J. Chung, S. G. Rhee, J. Biol. Chem. 269, 27670 (1994).
12. H. Z. Chae, T. B. Uhm, S. G. Rhee, Proc. Natl. Acad. Sci. U.S.A. 91, 7022 (1994).
13. H. A. Woo et al., Science 300, 653 (2003).
14. G. Georgiou, L. Masip, Science 300, 592 (2003).
15. A. Mitsumoto, Y. Takanezawa, K. Okawa, A. Iwamatsu, Y. Nakagawa, Free Radic. Biol. Med. 30, 625 (2001).
16. M. Chevallet et al., J. Biol. Chem. 278, 37146 (2003).
17. B. Biteau, J. Labarre, M. B. Toledano, Nature 425, 980 (2003).
18. A. V. Budanov et al., Oncogene 21, 6017 (2002).
19. H. Peeters et al., Hum. Genet. 112, 573 (2003).
20. Materials and methods are available as supporting material on Science Online.
21. S. Velasco-Miguel et al., Oncogene 18, 127 (1999).
22. S. F. Altschul et al., Nucleic Acids Res. 25, 3389 (1997).
23. C. M. Nunn, S. Djordjevic, P. J. Hillas, C. R. Nishida, P. R. Ortiz de Montellano, J. Biol. Chem. 277, 20033 (2002).
24. R. Bryk, C. D. Lima, H. Erdjument-Bromage, P. Tempst, C. Nathan, Science 295, 1073 (2002); published online 17 January 2002; 10.1126/science.1067798.
25. L. A. Kelley, R. M. MacCallum, M. J. Sternberg, J. Mol. Biol. 299, 499 (2000).
26. A. Koshkin, C. M. Nunn, S. Djordjevic, P. R. Ortiz de Montellano, J. Biol. Chem. 278, 29502 (2003).
27. H. Sies, Eur. J. Biochem. 215, 213 (1993).
28. O. W. Griffith, A. Meister, J. Biol. Chem. 254, 7558 (1979).
29. J. Nordberg, L. Zhong, A. Holmgren, E. S. Arner, J. Biol. Chem. 273, 10835 (1998).
30. A. V. Budanov, A. A. Sablina, E. Feinstein, E. V. Koonin, P. M. Chumakov, unpublished data.
31. Single-letter abbreviations for the amino acid residues areas as follows: A, Ala; C, Cys; D, Asp; E, Glu; F, Phe; G, Gly; H, His; I, Ile; K, Lys; L, Leu; M, Met; N, Asn; P, Pro; Q, Gln; R, Arg; S, Ser; T, Thr; V, Val; W, Trp; and Y, Tyr.
32. G. D. Schuter, S. F. Altschul, D. J. Lipman, Proteins 9, 180 (1991).
33. We thank I. Verma for the lentivirus vector system used for expression experiments, M. Chernov for sharing expertise in 2D gel separations, and G. Stark and A. Gudkov for critical reading of the manuscript. The work was supported by funds provided by the Lemer Research Institute to P.M.C.