Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity

Journal of Biological Chemistry

Volumn 285, Issue 12, 2010, Pages 9292-9300

  Pi, Jingbo ^a   Leung, Laura ^a   Xue, Peng ^c   Wang, Weiping ^a   Hou, Yongyong ^c   Liu, Dianxin ^c   Yehuda Shnaidman, Einav ^c   Lee, Candy ^a   Lau, Jackie ^a   Kurtz, Theodore W ^b   Chan, Jefferson Y ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTE DIFFERENTIATION; ADIPOCYTES; ADIPOGENESIS; ADIPOSE TISSUE; CHROMATIN IMMUNOPRECIPITATION; DIET-INDUCED OBESITY; DOWNSTREAM TARGET; ENHANCER-BINDING PROTEINS; HIGH-FAT DIET; KNOCK OUTS; LEUCINE ZIPPERS; MASTER REGULATORS; MOUSE EMBRYONIC FIBROBLASTS; NEGATIVE REGULATORS; NUCLEAR FACTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PHASE II; PREADIPOCYTES; PROMOTER ACTIVITIES; WEIGHT GAIN; XENOBIOTIC METABOLISM;

AMINO ACIDS; BINDING ENERGY; BINDING SITES; BIOCHEMISTRY; CELL CULTURE; DETOXIFICATION; MOLECULAR WEIGHT; NUCLEIC ACIDS; NUTRITION; TRANSCRIPTION; TRANSCRIPTION FACTORS;

GENE EXPRESSION REGULATION;

TRANSCRIPTION FACTOR NRF2;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FAT INTAKE; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE INTERACTION; GENETIC STABILITY; HORMONE RESPONSE; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; TRANSCRIPTION REGULATION; WEIGHT GAIN; ANIMAL; C57BL MOUSE; CELL STRAIN 3T3; DIET; FIBROBLAST; GENETICS; METABOLISM; MOUSE MUTANT; MOVEMENT (PHYSIOLOGY); PHYSIOLOGY; PROMOTER REGION;

MUS;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; DIET; DIETARY FATS; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOVEMENT; NF-E2-RELATED FACTOR 2; OBESITY; PROMOTER REGIONS, GENETIC;

EID: 77950553993     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.093955     Document Type: Article

References (32)

1. Rosen, E. D., and Spiegelman, B. M. (2006) Nature 444, 847-853
2. Feige, J. N., Gelman, L., Michalik, L., Desvergne, B., and Wahli, W. (2006) Prog. Lipid Res. 45, 120-159
3. Tontonoz, P., and Spiegelman, B. M. (2008) Annu. Rev. Biochem. 77, 289-312
4. Darlington, G. J., Ross, S. E., and MacDougald, O. A. (1998) J. Biol. Chem. 273, 30057-30060
5. Otto, T. C., and Lane, M. D. (2005) Crit. Rev. Biochem. Mol. Biol. 40, 229-242
6. Cao, Z., Umek, R. M., and McKnight, S. L. (1991) Genes Dev. 5, 1538-1552
7. Yeh, W. C., Cao, Z., Classon, M., and McKnight, S. L. (1995) Genes Dev. 9, 168-181
8. Christy, R. J., Kaestner, K. H., Geiman, D. E., and Lane, M. D. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 2593-2597
9. Clarke, S. L., Robinson, C. E., and Gimble, J. M. (1997) Biochem. Biophys. Res. Commun. 240, 99-103
10. Wu, Z., Xie, Y., Bucher, N. L., and Farmer, S. R. (1995) Genes Dev. 9, 2350-2363
11. Shao, D., and Lazar, M. A. (1997) J. Biol. Chem. 272, 21473-21478
12. Wu, Z., Rosen, E. D., Brun, R., Hauser, S., Adelmant, G., Troy, A. E., McKeon, C., Darlington, G. J., and Spiegelman, B. M. (1999) Mol. Cell 3, 151-158
13. Freytag, S. O., Paielli, D. L., and Gilbert, J. D. (1994) Genes Dev. 8, 1654-1663
14. Rosen, E. D., Hsu, C. H., Wang, X., Sakai, S., Freeman, M. W., Gonzalez, F. J., and Spiegelman, B. M. (2002) Genes Dev. 16, 22-26
15. Lefterova, M. I., and Lazar, M. A. (2009) Trends Endocrinol. Metab. 20, 107-114
16. Kobayashi, M., and Yamamoto, M. (2006) Adv. Enzyme Regul. 46, 113-140
17. Chan, K., Lu, R., Chang, J. C., and Kan, Y. W. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 13943-13948
18. Yoshinari, K., Okino, N., Sato, T., Sugatani, J., and Miwa, M. (2006) Drug Metab. Dispos. 34, 1081-1089
19. Kim, S., Sohn, I., Ahn, J. I., Lee, K. H., Lee, Y. S., and Lee, Y. S. (2004) Gene 340, 99-109
20. Zhou, J., Febbraio, M., Wada, T., Zhai, Y., Kuruba, R., He, J., Lee, J. H., Khadem, S., Ren, S., Li, S., Silverstein, R. L., and Xie, W. (2008) Gastroenterology 134, 556-567
21. Leung, L., Kwong, M., Hou, S., Lee, C., and Chan, J. Y. (2003) J. Biol. Chem. 278, 48021-48029
22. Pi, J., Bai, Y., Daniel, K. W., Liu, D., Lyght, O., Edelstein, D., Brownlee, M., Corkey, B. E., and Collins, S. (2009) Endocrinology 150, 3040-3048
23. Wang, W., Kwok, A. M., and Chan, J. Y. (2007) J. Biol. Chem. 282, 24670-24678
24. Rosen, E. D., and MacDougald, O. A. (2006) Nat. Rev. Mol. Cell Biol. 7, 885-896
25. Zhu, Y., Qi, C., Korenberg, J. R., Chen, X. N., Noya, D., Rao, M. S., and Reddy, J. K. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 7921-7925
26. Cho, H. Y., Reddy, S. P., Debiase, A., Yamamoto, M., and Kleeberger, S. R. (2005) Free Radic. Biol. Med. 38, 325-343
27. Tanaka, Y., Aleksunes, L. M., Yeager, R. L., Gyamfi, M. A., Esterly, N., Guo, G. L., and Klaassen, C. D. (2008) J. Pharmacol. Exp. Ther. 325, 655-664
28. Gummersbach, C., Hemmrich, K., Kröncke, K. D., Suschek, C. V., Fehsel, K., and Pallua, N. (2009) Differentiation 77, 115-120
29. Shin, S., Wakabayashi, N., Misra, V., Biswal, S., Lee, G. H., Agoston, E. S., Yamamoto, M., and Kensler, T. W. (2007) Mol. Cell. Biol. 27, 7188-7197
30. Shin, S., Wakabayashi, J., Yates, M. S., Wakabayashi, N., Dolan, P. M., Aja, S., Liby, K. T., Sporn, M. B., Yamamoto, M., and Kensler, T. W. (2009) Eur. J. Pharmacol. 620, 138-144
31. Echtay, K. S., Roussel, D., St.-Pierre, J., Jekabsons, M. B., Cadenas, S., Stuart, J. A., Harper, J. A., Roebuck, S. J., Morrison, A., Pickering, S., Clapham, J. C., and Brand, M. D. (2002) Nature 415, 96-99
32. Surwit, R. S., Wang, S., Petro, A. E., Sanchis, D., Raimbault, S., Ricquier, D., and Collins, S. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 4061-4065