Impaired Mitochondrial Dynamics and Nrf2 Signaling Contribute to Compromised Responses to Oxidative Stress in Striatal Cells Expressing Full-Length Mutant Huntingtin

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Jin, Youngnam N ^a   Yu, Yanxun V ^a   Gundemir, Soner ^a   Jo, Chulman ^a   Cui, Mei ^b   Tieu, Kim ^b   Johnson, Gail V W ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MUTANT PROTEIN; PROTEIN DRP1; PROTEIN OPA1; PROTEIN P62; REGULATOR PROTEIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL COUNT; CELL FUSION; CELL STRESS; CELL TYPE; CONTROLLED STUDY; CORPUS STRIATUM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; MITOCHONDRIAL DYNAMICS; MITOCHONDRION SWELLING; MOUSE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TARGET CELL; TRANSCRIPTION INITIATION;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE, TRANSFORMED; DYNAMINS; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; GENES, REPORTER; GTP PHOSPHOHYDROLASES; HUMANS; HUNTINGTON DISEASE; LUCIFERASES; MICE; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; MUTATION; NEOSTRIATUM; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84874564486     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057932     Document Type: Article

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