Breaking a pathogen's iron will: Inhibiting siderophore production as an antimicrobial strategy

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1854, Issue 8, 2015, Pages 1054-1070

  Lamb, Audrey L ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Nonribosomal peptide synthetase; NRPS independent synthetase; Polyketide synthase; Siderophore

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; DIHYDROXYBENZOLATE ADENYLATION INHIBITOR; ENZYME INHIBITOR; IRON; ISOCHORISMATE PYRUVATE LYASE; ISOCHORISMATE SYNTHASE; LYASE; MACROCYCLIC INHIBITOR; NONRIBOSOMAL PEPTIDE SYNTHETASE; NONRIBOSOMAL PEPTIDE SYNTHETASE INHIBITOR; ORNITHINE DECARBOXYLASE; ORNITHINE HYDROXYLASE; PHOSPHOPANTETHEINYL TRANSFERASE INHIBITOR; POLYKETIDE SYNTHASE; SALICYLATE ADENYLATION INHIBITOR; SALICYLATE SYNTHASE; SALICYLIC ACID; SIDEROPHORE; SYNTHETASE; TRANSFERASE INHIBITOR; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; VINYLSULFONAMIDE INHIBITOR;

ADENYLATION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ASPERGILLUS FUMIGATUS; BIOSYNTHESIS; CELL WALL; DRUG DESIGN; DRUG SYNTHESIS; HOSPITAL INFECTION; HOST; HUMAN; IMMUNITY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; REVIEW; RIBOSOME; SYNTHESIS; YERSINIA ENTEROCOLITICA; ANTIFUNGAL RESISTANCE; BACTERIAL INFECTIONS; CHEMISTRY; DRUG EFFECTS; METABOLISM; MYCOSES;

BACTERIA (MICROORGANISMS);

ANTI-INFECTIVE AGENTS; BACTERIAL INFECTIONS; DRUG RESISTANCE, BACTERIAL; DRUG RESISTANCE, FUNGAL; IRON; MYCOSES; SIDEROPHORES;

EID: 84930225222     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2015.05.001     Document Type: Review

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