Aminoacyl adenylate substrate analogues for the inhibition of adenylation domains of nonribosomal peptide synthetases

ChemBioChem

Volumn 4, Issue 9, 2003, Pages 903-906

  Finking, Robert ^a   Neumüller, Andrea ^a   Solsbacher, Jens ^b   Konz, Dirk ^b   Kretzschmar, Gerhard ^c   Schweitzer, Markus ^c   Krumm, Thomas ^c   Marahiel, Mohamed A ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b Building G 830   (Germany)

^c SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Adenylation domain; Enzymes; Inhibitors; Nonribosomal peptide synthetases; Synthetases

Indexed keywords

5' O [N (LEUCYL)SULFAMOYL]ADENOSINE; 5' O [N (PHENYLALANYL)SULFAMOYL]ADENOSINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; AMINOACYL TRANSFER RNA; AMINOACYLADENOSINE; ENZYME INHIBITOR; LEUCINE; PEPTIDE SYNTHASE; PHENYLALANINE; PHOSPHATE; RIBOSE; SURFACTIN; UNCLASSIFIED DRUG;

ADENYLATION; ARTICLE; CRYSTALLIZATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; EVOLUTION; MICHAELIS CONSTANT; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE; AMINO ACYL-TRNA SYNTHETASES; ENZYME INHIBITORS; LEUCINE; PEPTIDE SYNTHASES; PHENYLALANINE; SUBSTRATE SPECIFICITY;

EID: 0141795294     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200300666     Document Type: Article

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