Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism

Biochemistry

Volumn 51, Issue 33, 2012, Pages 6493-6495

  Sundlov, Jesse A ^a,b   Fontaine, Danielle M ^c   Southworth, Tara L ^c   Branchini, Bruce R ^c   Gulick, Andrew M ^a,b  

^a HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c The Holleran Center for Community Action and Public Policy   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL-COA; ADENYLATION; BIOCHEMICAL MECHANISMS; C-TERMINAL DOMAINS; CATALYTIC MECHANISMS; FIREFLY LUCIFERASE; LUCIFERASE ENZYMES; OXIDATIVE DECARBOXYLATION; PARTIAL REACTIONS; SYNTHETASES; TWO-STEP REACTIONS;

CARBOXYLATION; CONFORMATIONS; ENZYMES;

PLANTS (BOTANY);

LONG CHAIN FATTY ACID COENZYME A LIGASE; LUCIFERASE;

ARTICLE; BIOLUMINESCENCE; CATALYSIS; CONFORMATION; CRYSTAL STRUCTURE; ENZYME MECHANISM; FIREFLY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE MONOPHOSPHATE; BINDING SITES; CATALYSIS; COENZYME A LIGASES; CRYSTALLOGRAPHY, X-RAY; LUCIFERASES, FIREFLY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 84865408770     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300934s     Document Type: Article

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