Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 11, 2012, Pages 4110-4115

  Kapur, Shiven ^a   Lowry, Brian ^b   Yuzawa, Satoshi ^a   Kenthirapalan, Sanketha ^a   Chen, Alice Y ^b   Cane, David E ^c   Khosla, Chaitan ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 DEOXYERYTHRONOLIDE B SYNTHASE; ACYL CARRIER PROTEIN; ANTIBIOTIC AGENT; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; ENZYME ENGINEERING; ENZYME MECHANISM; MOLECULAR DOCKING; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RNA TRANSLATION; SITE DIRECTED MUTAGENESIS; STEREOCHEMISTRY;

ACYL CARRIER PROTEIN; AMINO ACID SEQUENCE; BIOCATALYSIS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POLYKETIDE SYNTHASES; POLYKETIDES; PROTEIN ENGINEERING; PROTEIN TRANSPORT; SUBSTRATE SPECIFICITY;

EID: 84858184688     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118734109     Document Type: Article

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