Genetic manipulation of non-ribosomal peptide synthetases to generate novel bioactive peptide products

Biotechnology Letters

Volumn 36, Issue 12, 2014, Pages 2407-2416

  Calcott, Mark J ^a   Ackerley, David F ^a,b  

^a VICTORIA UNIVERSITY OF WELLINGTON   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Biosynthesis; Directed evolution; Domain substitution; Module swapping; Non ribosomal peptide synthetases; Rational engineering; Secondary metabolite

Indexed keywords

ASSEMBLY; ASSEMBLY MACHINES; BIOCHEMISTRY; BIOSYNTHESIS; METABOLITES; RATIONAL FUNCTIONS; SYNTHETIC BIOLOGY;

DIRECTED EVOLUTION; DOMAIN SUBSTITUTION; MODULE SWAPPING; SECONDARY METABOLITES; SYNTHETASES;

PEPTIDES;

BIOLOGICAL PRODUCT; NONRIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDE; PEPTIDE SYNTHASE;

BIOTECHNOLOGY; GENETICS; METABOLIC ENGINEERING; METABOLISM; PROCEDURES; PROTEIN SYNTHESIS;

BIOLOGICAL PRODUCTS; BIOTECHNOLOGY; METABOLIC ENGINEERING; PEPTIDE SYNTHASES; PEPTIDES; PROTEIN BIOSYNTHESIS;

EID: 84911484355     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-014-1642-y     Document Type: Review

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