A fluorescence polarization binding assay to identify inhibitors of flavin-dependent monooxygenases

Analytical Biochemistry

Volumn 425, Issue 1, 2012, Pages 80-87

  Qi, Jun ^a   Kizjakina, Karina ^a   Robinson, Reeder ^a   Tolani, Karishma ^a   Sobrado, Pablo ^a,b  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b Fralin Life Science Institute   (United States)

Author keywords

Flavin dependent monooxygenases; Huntington's and Alzheimer's diseases; Kynurenine monooxygenase; Lysine hydroxylase; Ornithine hydroxylase; Siderophore

Indexed keywords

AMINO ACIDS; ASPERGILLUS; BACTERIA; BIOCHEMISTRY; CHROMOPHORES; DIMETHYL SULFOXIDE; FLUORESCENCE; POLARIZATION; SYNTHESIS (CHEMICAL);

ALZHEIMER'S DISEASE; ASPERGILLUS FUMIGATUS; FLUORESCENCE POLARIZATION; HYDROXYLASES; MONOOXYGENASES; MYCOBACTERIUM SMEGMATIS; NEURODEGENERATIVE DISORDERS; SIDEROPHORES;

NEURODEGENERATIVE DISEASES;

ADENOSINE DIPHOSPHATE; DIMETHYL SULFOXIDE; FLAVIN DEPENDENT MONOOXYGENASE; FLAVIN DEPENDENT MONOOXYGENASE INHIBITOR; KYNURENINE MONOOXYGENASE; N HYDROXYLATING MONOOXYGENASE; OXYGENASE INHIBITOR; QUERCETIN; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; ASPERGILLUS FUMIGATUS; BINDING ASSAY; CHROMATOPHORE; CONTROLLED STUDY; ENZYME BINDING; ENZYME SUBSTRATE; FLUORESCENCE POLARIZATION; HEAT TOLERANCE; INCUBATION TIME; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PRIORITY JOURNAL;

ASPERGILLUS FUMIGATUS; FUNGI; MYCOBACTERIUM SMEGMATIS; TRYPANOSOMA BRUCEI;

EID: 84859647304     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.03.002     Document Type: Article

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