Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 10, 2013, Pages 5138-5140

  Lun, Shichun ^a   Guo, Haidan ^a   Adamson, John ^b   Cisar, Justin S ^c   Davis, Tony D ^c,d   Chavadi, Sivagami Sundaram ^e   Warren, J David ^f   Quadri, Luis E N ^e   Tan, Derek S ^c,d   Bishai, William R ^a,b,g  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AFRICA HEALTH RESEARCH INSTITUTE   (South Africa)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d Weill Cornell Graduate School of Biomedical Sciences   (United States)

^e CITY UNIVERSITY OF NEW YORK   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' O ( N SALICYLSULFAMOYL)ADENOSINE; ANTIBIOTIC AGENT; ANTIMYCOBACTERIAL AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFICACY; FEMALE; IN VIVO STUDY; LUNG; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; MONOTHERAPY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; TUBERCULOSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; FEMALE; LUNG; MICE; MICE, INBRED BALB C; MYCOBACTERIUM TUBERCULOSIS; OXAZOLES; RANDOM ALLOCATION;

EID: 84884225510     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00918-13     Document Type: Article

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