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Volumn 26, Issue 6, 2015, Pages 571-584

Mechanisms of enhanced insulin secretion and sensitivity with n-3 unsaturated fatty acids

Author keywords

Adipokines; Inflammation; Insulin; N 3 polyunsaturated fatty acids; Obesity

Indexed keywords

ADIPOCYTOKINE; APELIN; DOCOSAHEXAENOIC ACID; GLUCAGON LIKE PEPTIDE 1; GUANINE NUCLEOTIDE BINDING PROTEIN; ICOSAPENTAENOIC ACID; INSULIN; LINOLENIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; SOMATOMEDIN C; UNSATURATED FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

EID: 84928926236     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2015.02.001     Document Type: Review
Times cited : (109)

References (232)
  • 1
    • 78651276631 scopus 로고    scopus 로고
    • American Diabetes A, Diagnosis and classification of diabetes mellitus
    • American Diabetes A Diagnosis and classification of diabetes mellitus. Diabetes Care 2011, 34(Suppl 1):S62-S69.
    • (2011) Diabetes Care , vol.34 , pp. S62-S69
  • 2
    • 77951089891 scopus 로고    scopus 로고
    • International Diabetes Federation, Brussels, Belgium
    • International Diabetes Federation IDF diabetes atlas 2013, International Diabetes Federation, Brussels, Belgium, [http://www.idf.org/sites/default/files/Atlas-poster-2014EN.pdf]. 6th ed.
    • (2013) IDF diabetes atlas
  • 3
    • 0035130272 scopus 로고    scopus 로고
    • β-cell adaptation and decompensation during the progression of diabetes
    • Weir G.C., Laybutt D.R., Kaneto H., Bonner-Weir S., Sharma A. β-cell adaptation and decompensation during the progression of diabetes. Diabetes 2001, 50(Suppl 1):S154-S159.
    • (2001) Diabetes , vol.50 , pp. S154-S159
    • Weir, G.C.1    Laybutt, D.R.2    Kaneto, H.3    Bonner-Weir, S.4    Sharma, A.5
  • 4
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities
    • Cnop M., Welsh N., Jonas J.C., Jorns A., Lenzen S., Eizirik D.L. Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 2005, 54(Suppl 2):S97-S107.
    • (2005) Diabetes , vol.54 , pp. S97-S107
    • Cnop, M.1    Welsh, N.2    Jonas, J.C.3    Jorns, A.4    Lenzen, S.5    Eizirik, D.L.6
  • 5
    • 0032934826 scopus 로고    scopus 로고
    • Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study
    • Krssak M., Falk Petersen K., Dresner A., DiPietro L., Vogel S.M., Rothman D.L., et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 1999, 42:113-116.
    • (1999) Diabetologia , vol.42 , pp. 113-116
    • Krssak, M.1    Falk Petersen, K.2    Dresner, A.3    DiPietro, L.4    Vogel, S.M.5    Rothman, D.L.6
  • 6
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: common threads and missing links
    • Samuel V.T., Shulman G.I. Mechanisms for insulin resistance: common threads and missing links. Cell 2012, 148:852-871.
    • (2012) Cell , vol.148 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 7
    • 66849124938 scopus 로고    scopus 로고
    • Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes
    • Le K.A., Ith M., Kreis R., Faeh D., Bortolotti M., Tran C., et al. Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes. Am J Clin Nutr 2009, 89:1760-1765.
    • (2009) Am J Clin Nutr , vol.89 , pp. 1760-1765
    • Le, K.A.1    Ith, M.2    Kreis, R.3    Faeh, D.4    Bortolotti, M.5    Tran, C.6
  • 8
    • 0036299262 scopus 로고    scopus 로고
    • Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus
    • Ravussin E., Smith S.R. Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus. Ann N Y Acad Sci 2002, 967:363-378.
    • (2002) Ann N Y Acad Sci , vol.967 , pp. 363-378
    • Ravussin, E.1    Smith, S.R.2
  • 9
    • 3843061127 scopus 로고    scopus 로고
    • Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
    • Chen G., Liang G., Ou J., Goldstein J.L., Brown M.S. Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc Natl Acad Sci U S A 2004, 101:11245-11250.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11245-11250
    • Chen, G.1    Liang, G.2    Ou, J.3    Goldstein, J.L.4    Brown, M.S.5
  • 10
    • 77957302090 scopus 로고    scopus 로고
    • Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c
    • Ferre P., Foufelle F. Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c. Diabetes Obes Metab 2010, 12(Suppl 2):83-92.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 83-92
    • Ferre, P.1    Foufelle, F.2
  • 11
    • 33646133412 scopus 로고    scopus 로고
    • PPAR-alpha and insulin sensitivity
    • Haluzik M.M., Haluzik M. PPAR-alpha and insulin sensitivity. Physiol Res 2006, 55:115-122.
    • (2006) Physiol Res , vol.55 , pp. 115-122
    • Haluzik, M.M.1    Haluzik, M.2
  • 12
    • 13744249406 scopus 로고    scopus 로고
    • PPARγ-mediated insulin sensitization: the importance of fat versus muscle
    • Kintscher U., Law R.E. PPARγ-mediated insulin sensitization: the importance of fat versus muscle. Am J Physiol Endocrinol Metab 2005, 288:E287-E291.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E287-E291
    • Kintscher, U.1    Law, R.E.2
  • 13
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • Holst J.J. The physiology of glucagon-like peptide 1. Physiol Rev 2007, 87:1409-1439.
    • (2007) Physiol Rev , vol.87 , pp. 1409-1439
    • Holst, J.J.1
  • 14
    • 84861982113 scopus 로고    scopus 로고
    • Metabolic actions of IGF-1 in normal physiology and diabetes
    • Clemmons D.R. Metabolic actions of IGF-1 in normal physiology and diabetes. Endocrinol Metab Clin North Am 2012, 41:425-443.
    • (2012) Endocrinol Metab Clin North Am , vol.41 , pp. 425-443
    • Clemmons, D.R.1
  • 15
    • 80051824524 scopus 로고    scopus 로고
    • Apelin and insulin resistance: another arrow for the quiver?
    • Xu S., Tsao P.S., Yue P. Apelin and insulin resistance: another arrow for the quiver?. J Diabetes 2011, 3:225-231.
    • (2011) J Diabetes , vol.3 , pp. 225-231
    • Xu, S.1    Tsao, P.S.2    Yue, P.3
  • 17
    • 84880974817 scopus 로고    scopus 로고
    • Adipokines mediate inflammation and insulin resistance
    • Kwon H., Pessin J.E. Adipokines mediate inflammation and insulin resistance. Front Endocrinol (Lausanne) 2013, 4:71.
    • (2013) Front Endocrinol (Lausanne) , vol.4 , pp. 71
    • Kwon, H.1    Pessin, J.E.2
  • 18
    • 39149143637 scopus 로고    scopus 로고
    • Adipokines: the missing link between insulin resistance and obesity
    • Antuna-Puente B., Feve B., Fellahi S., Bastard J.P. Adipokines: the missing link between insulin resistance and obesity. Diabetes Metab 2008, 34:2-11.
    • (2008) Diabetes Metab , vol.34 , pp. 2-11
    • Antuna-Puente, B.1    Feve, B.2    Fellahi, S.3    Bastard, J.P.4
  • 19
    • 57649195613 scopus 로고    scopus 로고
    • Dietary fats and prevention of type 2 diabetes
    • Riserus U., Willett W.C., Hu F.B. Dietary fats and prevention of type 2 diabetes. Prog Lipid Res 2009, 48:44-51.
    • (2009) Prog Lipid Res , vol.48 , pp. 44-51
    • Riserus, U.1    Willett, W.C.2    Hu, F.B.3
  • 20
    • 49649089562 scopus 로고    scopus 로고
    • Effect of the dietary fat quality on insulin sensitivity
    • Galgani J.E., Uauy R.D., Aguirre C.A., Diaz E.O. Effect of the dietary fat quality on insulin sensitivity. Br J Nutr 2008, 100:471-479.
    • (2008) Br J Nutr , vol.100 , pp. 471-479
    • Galgani, J.E.1    Uauy, R.D.2    Aguirre, C.A.3    Diaz, E.O.4
  • 21
    • 84857352823 scopus 로고    scopus 로고
    • Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function
    • Martins A.R., Nachbar R.T., Gorjao R., Vinolo M.A., Festuccia W.T., Lambertucci R.H., et al. Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function. Lipids Health Dis 2012, 11:30.
    • (2012) Lipids Health Dis , vol.11 , pp. 30
    • Martins, A.R.1    Nachbar, R.T.2    Gorjao, R.3    Vinolo, M.A.4    Festuccia, W.T.5    Lambertucci, R.H.6
  • 23
    • 79960685355 scopus 로고    scopus 로고
    • Omega-3 fatty acids and metabolic syndrome: effects and emerging mechanisms of action
    • Poudyal H., Panchal S.K., Diwan V., Brown L. Omega-3 fatty acids and metabolic syndrome: effects and emerging mechanisms of action. Prog Lipid Res 2011, 50:372-387.
    • (2011) Prog Lipid Res , vol.50 , pp. 372-387
    • Poudyal, H.1    Panchal, S.K.2    Diwan, V.3    Brown, L.4
  • 24
    • 84862565767 scopus 로고    scopus 로고
    • Chronic high-carbohydrate, high-fat feeding in rats induces reversible metabolic, cardiovascular, and liver changes
    • Poudyal H., Panchal S.K., Ward L.C., Waanders J., Brown L. Chronic high-carbohydrate, high-fat feeding in rats induces reversible metabolic, cardiovascular, and liver changes. Am J Physiol Endocrinol Metab 2012, 302:E1472-E1482.
    • (2012) Am J Physiol Endocrinol Metab , vol.302 , pp. E1472-E1482
    • Poudyal, H.1    Panchal, S.K.2    Ward, L.C.3    Waanders, J.4    Brown, L.5
  • 25
    • 84878014437 scopus 로고    scopus 로고
    • Effects of ALA, EPA and DHA in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats
    • Poudyal H., Panchal S.K., Ward L.C., Brown L. Effects of ALA, EPA and DHA in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats. J Nutr Biochem 2013, 24:1041-1052.
    • (2013) J Nutr Biochem , vol.24 , pp. 1041-1052
    • Poudyal, H.1    Panchal, S.K.2    Ward, L.C.3    Brown, L.4
  • 27
    • 84881026099 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids reduce insulin resistance and triglycerides in obese children and adolescents
    • Juarez-Lopez C., Klunder-Klunder M., Madrigal-Azcarate A., Flores-Huerta S. Omega-3 polyunsaturated fatty acids reduce insulin resistance and triglycerides in obese children and adolescents. Pediatr Diabetes 2013, 14:377-383.
    • (2013) Pediatr Diabetes , vol.14 , pp. 377-383
    • Juarez-Lopez, C.1    Klunder-Klunder, M.2    Madrigal-Azcarate, A.3    Flores-Huerta, S.4
  • 28
    • 84875216247 scopus 로고    scopus 로고
    • Role of dietary n-3 polyunsaturated fatty acids in type 2 diabetes: a review of epidemiological and clinical studies
    • Jafari T., Fallah A.A., Azadbakht L. Role of dietary n-3 polyunsaturated fatty acids in type 2 diabetes: a review of epidemiological and clinical studies. Maturitas 2013, 74:303-308.
    • (2013) Maturitas , vol.74 , pp. 303-308
    • Jafari, T.1    Fallah, A.A.2    Azadbakht, L.3
  • 29
    • 61949365497 scopus 로고    scopus 로고
    • Prevention of insulin resistance by n-3 polyunsaturated fatty acids
    • Fedor D., Kelley D.S. Prevention of insulin resistance by n-3 polyunsaturated fatty acids. Curr Opin Clin Nutr Metab Care 2009, 12:138-146.
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , pp. 138-146
    • Fedor, D.1    Kelley, D.S.2
  • 30
    • 47249102647 scopus 로고    scopus 로고
    • Dietary eicosapentaenoic acid and docosahexaenoic acid are more effective than alpha-linolenic acid in improving insulin sensitivity in rats
    • Andersen G., Harnack K., Erbersdobler H.F., Somoza V. Dietary eicosapentaenoic acid and docosahexaenoic acid are more effective than alpha-linolenic acid in improving insulin sensitivity in rats. Ann Nutr Metab 2008, 52:250-256.
    • (2008) Ann Nutr Metab , vol.52 , pp. 250-256
    • Andersen, G.1    Harnack, K.2    Erbersdobler, H.F.3    Somoza, V.4
  • 31
    • 84860994990 scopus 로고    scopus 로고
    • 'Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition
    • Agrawal R., Gomez-Pinilla F. 'Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition. J Physiol 2012, 590:2485-2499.
    • (2012) J Physiol , vol.590 , pp. 2485-2499
    • Agrawal, R.1    Gomez-Pinilla, F.2
  • 32
    • 33846999679 scopus 로고    scopus 로고
    • Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity
    • Gingras A.A., White P.J., Chouinard P.Y., Julien P., Davis T.A., Dombrowski L., et al. Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity. J Physiol 2007, 579:269-284.
    • (2007) J Physiol , vol.579 , pp. 269-284
    • Gingras, A.A.1    White, P.J.2    Chouinard, P.Y.3    Julien, P.4    Davis, T.A.5    Dombrowski, L.6
  • 33
    • 84875506824 scopus 로고    scopus 로고
    • Fish oil positively regulates anabolic signalling alongside an increase in whole-body gluconeogenesis in ageing skeletal muscle
    • Kamolrat T., Gray S.R., Thivierge M.C. Fish oil positively regulates anabolic signalling alongside an increase in whole-body gluconeogenesis in ageing skeletal muscle. Eur J Nutr 2013, 52:647-657.
    • (2013) Eur J Nutr , vol.52 , pp. 647-657
    • Kamolrat, T.1    Gray, S.R.2    Thivierge, M.C.3
  • 34
    • 36749077040 scopus 로고    scopus 로고
    • Glucose intolerance associated to insulin resistance and increased insulin secretion in rats depleted in long-chain ω3 fatty acids
    • Cancelas J., Prieto P.G., Villanueva-Penacarrillo M.L., Zhang Y., Portois L., Sener A., et al. Glucose intolerance associated to insulin resistance and increased insulin secretion in rats depleted in long-chain ω3 fatty acids. Horm Metab Res 2007, 39:823-825.
    • (2007) Horm Metab Res , vol.39 , pp. 823-825
    • Cancelas, J.1    Prieto, P.G.2    Villanueva-Penacarrillo, M.L.3    Zhang, Y.4    Portois, L.5    Sener, A.6
  • 35
    • 67649363782 scopus 로고    scopus 로고
    • Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins
    • Gonzalez-Periz A., Horrillo R., Ferre N., Gronert K., Dong B., Moran-Salvador E., et al. Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins. FASEB J 2009, 23:1946-1957.
    • (2009) FASEB J , vol.23 , pp. 1946-1957
    • Gonzalez-Periz, A.1    Horrillo, R.2    Ferre, N.3    Gronert, K.4    Dong, B.5    Moran-Salvador, E.6
  • 36
    • 84878337941 scopus 로고    scopus 로고
    • α-Linolenic acid inhibits human renal cell carcinoma cell proliferation through PPAR-gamma activation and COX-2 inhibition
    • Yang L., Yuan J., Liu L., Shi C., Wang L., Tian F., et al. α-Linolenic acid inhibits human renal cell carcinoma cell proliferation through PPAR-gamma activation and COX-2 inhibition. Oncol Lett 2013, 6:197-202.
    • (2013) Oncol Lett , vol.6 , pp. 197-202
    • Yang, L.1    Yuan, J.2    Liu, L.3    Shi, C.4    Wang, L.5    Tian, F.6
  • 37
    • 34047166373 scopus 로고    scopus 로고
    • N-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-α-dependent manner
    • Neschen S., Morino K., Dong J., Wang-Fischer Y., Cline G.W., Romanelli A.J., et al. n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-α-dependent manner. Diabetes 2007, 56:1034-1041.
    • (2007) Diabetes , vol.56 , pp. 1034-1041
    • Neschen, S.1    Morino, K.2    Dong, J.3    Wang-Fischer, Y.4    Cline, G.W.5    Romanelli, A.J.6
  • 38
    • 82255179405 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acid and insulin sensitivity: a meta-analysis of randomized controlled trials
    • Akinkuolie A.O., Ngwa J.S., Meigs J.B., Djousse L. Omega-3 polyunsaturated fatty acid and insulin sensitivity: a meta-analysis of randomized controlled trials. Clin Nutr 2011, 30:702-707.
    • (2011) Clin Nutr , vol.30 , pp. 702-707
    • Akinkuolie, A.O.1    Ngwa, J.S.2    Meigs, J.B.3    Djousse, L.4
  • 39
    • 79957900616 scopus 로고    scopus 로고
    • Dynamics of insulin secretion and the clinical implications for obesity and diabetes
    • Seino S., Shibasaki T., Minami K. Dynamics of insulin secretion and the clinical implications for obesity and diabetes. J Clin Invest 2011, 121:2118-2125.
    • (2011) J Clin Invest , vol.121 , pp. 2118-2125
    • Seino, S.1    Shibasaki, T.2    Minami, K.3
  • 40
    • 0033842027 scopus 로고    scopus 로고
    • Interactions between insulin resistance and insulin secretion in the development of glucose intolerance
    • Cavaghan M.K., Ehrmann D.A., Polonsky K.S. Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. J Clin Invest 2000, 106:329-333.
    • (2000) J Clin Invest , vol.106 , pp. 329-333
    • Cavaghan, M.K.1    Ehrmann, D.A.2    Polonsky, K.S.3
  • 41
    • 33748513015 scopus 로고    scopus 로고
    • Pancreatic islet function in ω3 fatty acid-depleted rats: glucose metabolism and nutrient-stimulated insulin release
    • Oguzhan B., Zhang Y., Louchami K., Courtois P., Portois L., Chardigny J.M., et al. Pancreatic islet function in ω3 fatty acid-depleted rats: glucose metabolism and nutrient-stimulated insulin release. Endocrine 2006, 29:457-466.
    • (2006) Endocrine , vol.29 , pp. 457-466
    • Oguzhan, B.1    Zhang, Y.2    Louchami, K.3    Courtois, P.4    Portois, L.5    Chardigny, J.M.6
  • 42
    • 33748460709 scopus 로고    scopus 로고
    • Pancreatic islet function in ω-3 fatty acid-depleted rats: alteration of calcium fluxes and calcium-dependent insulin release
    • Zhang Y., Oguzhan B., Louchami K., Chardigny J.M., Portois L., Carpentier Y.A., et al. Pancreatic islet function in ω-3 fatty acid-depleted rats: alteration of calcium fluxes and calcium-dependent insulin release. Am J Physiol Endocrinol Metab 2006, 291:E441-E448.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , pp. E441-E448
    • Zhang, Y.1    Oguzhan, B.2    Louchami, K.3    Chardigny, J.M.4    Portois, L.5    Carpentier, Y.A.6
  • 44
    • 38049085928 scopus 로고    scopus 로고
    • + handling and secretory behaviour provoked by the intravenous administration of a medium-chain triglyceride: fish oil emulsion to long-chain polyunsaturated ω3 fatty acid-depleted rats
    • + handling and secretory behaviour provoked by the intravenous administration of a medium-chain triglyceride: fish oil emulsion to long-chain polyunsaturated ω3 fatty acid-depleted rats. Int J Mol Med 2006, 18:1047-1055.
    • (2006) Int J Mol Med , vol.18 , pp. 1047-1055
    • Louchami, K.1    Zhang, Y.2    Oguzhan, B.3    Delporte, C.4    Portois, L.5    Carpentier, Y.A.6
  • 45
    • 0344738796 scopus 로고    scopus 로고
    • Fish oil affects pancreatic fat storage, pyruvate dehydrogenase complex activity and insulin secretion in rats fed a sucrose-rich diet
    • Pighin D., Karabatas L., Rossi A., Chicco A., Basabe J.C., Lombardo Y.B. Fish oil affects pancreatic fat storage, pyruvate dehydrogenase complex activity and insulin secretion in rats fed a sucrose-rich diet. J Nutr 2003, 133:4095-4101.
    • (2003) J Nutr , vol.133 , pp. 4095-4101
    • Pighin, D.1    Karabatas, L.2    Rossi, A.3    Chicco, A.4    Basabe, J.C.5    Lombardo, Y.B.6
  • 46
    • 0842263178 scopus 로고    scopus 로고
    • Acute ω-3 fatty acid enrichment selectively reverses high-saturated fat feeding-induced insulin hypersecretion but does not improve peripheral insulin resistance
    • Holness M.J., Smith N.D., Greenwood G.K., Sugden M.C. Acute ω-3 fatty acid enrichment selectively reverses high-saturated fat feeding-induced insulin hypersecretion but does not improve peripheral insulin resistance. Diabetes 2004, 53(Suppl 1):S166-S171.
    • (2004) Diabetes , vol.53 , pp. S166-S171
    • Holness, M.J.1    Smith, N.D.2    Greenwood, G.K.3    Sugden, M.C.4
  • 47
    • 54749120144 scopus 로고    scopus 로고
    • Long-chain (n-3) polyunsaturated fatty acids prevent metabolic and vascular disorders in fructose-fed rats
    • Robbez Masson V., Lucas A., Gueugneau A.M., Macaire J.P., Paul J.L., Grynberg A., et al. Long-chain (n-3) polyunsaturated fatty acids prevent metabolic and vascular disorders in fructose-fed rats. J Nutr 2008, 138:1915-1922.
    • (2008) J Nutr , vol.138 , pp. 1915-1922
    • Robbez Masson, V.1    Lucas, A.2    Gueugneau, A.M.3    Macaire, J.P.4    Paul, J.L.5    Grynberg, A.6
  • 48
    • 0029925827 scopus 로고    scopus 로고
    • Effect of moderate levels of dietary fish oil on insulin secretion and sensitivity, and pancreas insulin content in normal rats
    • Chicco A., D'Alessandro M.E., Karabatas L., Gutman R., Lombardo Y.B. Effect of moderate levels of dietary fish oil on insulin secretion and sensitivity, and pancreas insulin content in normal rats. Ann Nutr Metab 1996, 40:61-70.
    • (1996) Ann Nutr Metab , vol.40 , pp. 61-70
    • Chicco, A.1    D'Alessandro, M.E.2    Karabatas, L.3    Gutman, R.4    Lombardo, Y.B.5
  • 49
    • 84855171612 scopus 로고    scopus 로고
    • The metabolic syndrome of fructose-fed rats: effects of long-chain polyunsaturated ω3 and ω6 fatty acids. III. Secretory behaviour of isolated pancreatic islets
    • Mellouk Z., Zhang Y., Bulur N., Louchami K., Malaisse W.J., Ait Yahia D., et al. The metabolic syndrome of fructose-fed rats: effects of long-chain polyunsaturated ω3 and ω6 fatty acids. III. Secretory behaviour of isolated pancreatic islets. Int J Mol Med 2012, 29:285-290.
    • (2012) Int J Mol Med , vol.29 , pp. 285-290
    • Mellouk, Z.1    Zhang, Y.2    Bulur, N.3    Louchami, K.4    Malaisse, W.J.5    Ait Yahia, D.6
  • 50
    • 0041419336 scopus 로고    scopus 로고
    • Diabetogenic impact of long-chain ω-3 fatty acids on pancreatic beta-cell function and the regulation of endogenous glucose production
    • Holness M.J., Greenwood G.K., Smith N.D., Sugden M.C. Diabetogenic impact of long-chain ω-3 fatty acids on pancreatic beta-cell function and the regulation of endogenous glucose production. Endocrinology 2003, 144:3958-3968.
    • (2003) Endocrinology , vol.144 , pp. 3958-3968
    • Holness, M.J.1    Greenwood, G.K.2    Smith, N.D.3    Sugden, M.C.4
  • 51
    • 79961165309 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperinsulinaemia-hyperaminoacidaemia in healthy young and middle-aged men and women
    • Smith G.I., Atherton P., Reeds D.N., Mohammed B.S., Rankin D., Rennie M.J., et al. Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperinsulinaemia-hyperaminoacidaemia in healthy young and middle-aged men and women. Clin Sci (Lond) 2011, 121:267-278.
    • (2011) Clin Sci (Lond) , vol.121 , pp. 267-278
    • Smith, G.I.1    Atherton, P.2    Reeds, D.N.3    Mohammed, B.S.4    Rankin, D.5    Rennie, M.J.6
  • 52
    • 84888614083 scopus 로고    scopus 로고
    • α-Linolenic acid attenuates doxorubicin-induced cardiotoxicity in rats through suppression of oxidative stress and apoptosis
    • Yu X., Cui L., Zhang Z., Zhao Q., Li S. α-Linolenic acid attenuates doxorubicin-induced cardiotoxicity in rats through suppression of oxidative stress and apoptosis. Acta Biochim Biophys Sin (Shanghai) 2013, 45:817-826.
    • (2013) Acta Biochim Biophys Sin (Shanghai) , vol.45 , pp. 817-826
    • Yu, X.1    Cui, L.2    Zhang, Z.3    Zhao, Q.4    Li, S.5
  • 53
    • 79959719801 scopus 로고    scopus 로고
    • α-Linolenic acid intake attenuates myocardial ischemia/reperfusion injury through anti-inflammatory and anti-oxidative stress effects in diabetic but not normal rats
    • Xie N., Zhang W., Li J., Liang H., Zhou H., Duan W., et al. α-Linolenic acid intake attenuates myocardial ischemia/reperfusion injury through anti-inflammatory and anti-oxidative stress effects in diabetic but not normal rats. Arch Med Res 2011, 42:171-181.
    • (2011) Arch Med Res , vol.42 , pp. 171-181
    • Xie, N.1    Zhang, W.2    Li, J.3    Liang, H.4    Zhou, H.5    Duan, W.6
  • 54
    • 84879804349 scopus 로고    scopus 로고
    • Alpha-linolenic acid exerts an endothelial protective effect against high glucose injury via PI3K/Akt pathway
    • Zhang W., Li R., Li J., Wang W., Tie R., Tian F., et al. Alpha-linolenic acid exerts an endothelial protective effect against high glucose injury via PI3K/Akt pathway. PLoS One 2013, 8:e68489.
    • (2013) PLoS One , vol.8 , pp. e68489
    • Zhang, W.1    Li, R.2    Li, J.3    Wang, W.4    Tie, R.5    Tian, F.6
  • 55
    • 34548611664 scopus 로고    scopus 로고
    • α-linolenic acid attenuates high glucose-induced apoptosis in cultured human umbilical vein endothelial cells via PI3K/Akt/eNOS pathway
    • Zhang W., Wang R., Han S.F., Bu L., Wang S.W., Ma H., et al. α-linolenic acid attenuates high glucose-induced apoptosis in cultured human umbilical vein endothelial cells via PI3K/Akt/eNOS pathway. Nutrition 2007, 23:762-770.
    • (2007) Nutrition , vol.23 , pp. 762-770
    • Zhang, W.1    Wang, R.2    Han, S.F.3    Bu, L.4    Wang, S.W.5    Ma, H.6
  • 56
    • 77449141236 scopus 로고    scopus 로고
    • Cellular production of n-3 PUFAs and reduction of n-6-to-n-3 ratios in the pancreatic β-cells and islets enhance insulin secretion and confer protection against cytokine-induced cell death
    • Wei D., Li J., Shen M., Jia W., Chen N., Chen T., et al. Cellular production of n-3 PUFAs and reduction of n-6-to-n-3 ratios in the pancreatic β-cells and islets enhance insulin secretion and confer protection against cytokine-induced cell death. Diabetes 2010, 59:471-478.
    • (2010) Diabetes , vol.59 , pp. 471-478
    • Wei, D.1    Li, J.2    Shen, M.3    Jia, W.4    Chen, N.5    Chen, T.6
  • 57
    • 79951914086 scopus 로고    scopus 로고
    • Effects of meals rich in either monounsaturated or saturated fat on lipid concentrations and on insulin secretion and action in subjects with high fasting triglyceride concentrations
    • Lopez S., Bermudez B., Ortega A., Varela L.M., Pacheco Y.M., Villar J., et al. Effects of meals rich in either monounsaturated or saturated fat on lipid concentrations and on insulin secretion and action in subjects with high fasting triglyceride concentrations. Am J Clin Nutr 2011, 93:494-499.
    • (2011) Am J Clin Nutr , vol.93 , pp. 494-499
    • Lopez, S.1    Bermudez, B.2    Ortega, A.3    Varela, L.M.4    Pacheco, Y.M.5    Villar, J.6
  • 58
    • 33646533329 scopus 로고    scopus 로고
    • Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans
    • Xiao C., Giacca A., Carpentier A., Lewis G.F. Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans. Diabetologia 2006, 49:1371-1379.
    • (2006) Diabetologia , vol.49 , pp. 1371-1379
    • Xiao, C.1    Giacca, A.2    Carpentier, A.3    Lewis, G.F.4
  • 59
    • 0032102146 scopus 로고    scopus 로고
    • A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion
    • Dobbins R.L., Chester M.W., Stevenson B.E., Daniels M.B., Stein D.T., McGarry J.D. A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion. J Clin Invest 1998, 101:2370-2376.
    • (1998) J Clin Invest , vol.101 , pp. 2370-2376
    • Dobbins, R.L.1    Chester, M.W.2    Stevenson, B.E.3    Daniels, M.B.4    Stein, D.T.5    McGarry, J.D.6
  • 60
    • 0031683543 scopus 로고    scopus 로고
    • Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans
    • Dobbins R.L., Chester M.W., Daniels M.B., McGarry J.D., Stein D.T. Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans. Diabetes 1998, 47:1613-1618.
    • (1998) Diabetes , vol.47 , pp. 1613-1618
    • Dobbins, R.L.1    Chester, M.W.2    Daniels, M.B.3    McGarry, J.D.4    Stein, D.T.5
  • 61
    • 0031716376 scopus 로고    scopus 로고
    • Acute lowering of plasma fatty acids lowers basal insulin secretion in diabetic and nondiabetic subjects
    • Boden G., Chen X., Iqbal N. Acute lowering of plasma fatty acids lowers basal insulin secretion in diabetic and nondiabetic subjects. Diabetes 1998, 47:1609-1612.
    • (1998) Diabetes , vol.47 , pp. 1609-1612
    • Boden, G.1    Chen, X.2    Iqbal, N.3
  • 62
    • 84920628213 scopus 로고    scopus 로고
    • In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity
    • Pereira S., Breen D.M., Naassan A.E., Wang P.Y.T., Uchino H., Fantus I.G. In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity. Metabolism 2015, 64:315-322.
    • (2015) Metabolism , vol.64 , pp. 315-322
    • Pereira, S.1    Breen, D.M.2    Naassan, A.E.3    Wang, P.Y.T.4    Uchino, H.5    Fantus, I.G.6
  • 63
    • 31144455960 scopus 로고    scopus 로고
    • Effect of alpha linolenic acid on cardiovascular risk markers: a systematic review
    • Wendland E., Farmer A., Glasziou P., Neil A. Effect of alpha linolenic acid on cardiovascular risk markers: a systematic review. Heart 2006, 92:166-169.
    • (2006) Heart , vol.92 , pp. 166-169
    • Wendland, E.1    Farmer, A.2    Glasziou, P.3    Neil, A.4
  • 64
    • 33748188924 scopus 로고    scopus 로고
    • Dietary linolenic acid and fasting glucose and insulin: the National Heart, Lung, and Blood Institute Family Heart Study
    • Djousse L., Hunt S.C., Tang W., Eckfeldt J.H., Province M.A., Ellison R.C. Dietary linolenic acid and fasting glucose and insulin: the National Heart, Lung, and Blood Institute Family Heart Study. Obesity (Silver Spring) 2006, 14:295-300.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 295-300
    • Djousse, L.1    Hunt, S.C.2    Tang, W.3    Eckfeldt, J.H.4    Province, M.A.5    Ellison, R.C.6
  • 65
    • 77952580966 scopus 로고    scopus 로고
    • Higher dietary intake of alpha-linolenic acid is associated with lower insulin resistance in middle-aged Japanese
    • Muramatsu T., Yatsuya H., Toyoshima H., Sasaki S., Li Y., Otsuka R., et al. Higher dietary intake of alpha-linolenic acid is associated with lower insulin resistance in middle-aged Japanese. Prev Med 2010, 50:272-276.
    • (2010) Prev Med , vol.50 , pp. 272-276
    • Muramatsu, T.1    Yatsuya, H.2    Toyoshima, H.3    Sasaki, S.4    Li, Y.5    Otsuka, R.6
  • 66
    • 61949365751 scopus 로고    scopus 로고
    • Flaxseed oil prevents trans-10, cis-12-conjugated linoleic acid-induced insulin resistance in mice
    • Kelley D.S., Vemuri M., Adkins Y., Gill S.H., Fedor D., Mackey B.E. Flaxseed oil prevents trans-10, cis-12-conjugated linoleic acid-induced insulin resistance in mice. Br J Nutr 2009, 101:701-708.
    • (2009) Br J Nutr , vol.101 , pp. 701-708
    • Kelley, D.S.1    Vemuri, M.2    Adkins, Y.3    Gill, S.H.4    Fedor, D.5    Mackey, B.E.6
  • 67
    • 14644419578 scopus 로고    scopus 로고
    • Substituting dietary linoleic acid with alpha-linolenic acid improves insulin sensitivity in sucrose fed rats
    • Ghafoorunissa, Ibrahim A., Natarajan S. Substituting dietary linoleic acid with alpha-linolenic acid improves insulin sensitivity in sucrose fed rats. Biochim Biophys Acta 2005, 1733:67-75.
    • (2005) Biochim Biophys Acta , vol.1733 , pp. 67-75
    • Ghafoorunissa Ibrahim, A.1    Natarajan, S.2
  • 68
    • 18044368848 scopus 로고    scopus 로고
    • Supplementation with α-linolenic acid-rich diacylglycerol suppresses fatty liver formation accompanied by an up-regulation of β-oxidation in Zucker fatty rats
    • Murase T., Aoki M., Tokimitsu I. Supplementation with α-linolenic acid-rich diacylglycerol suppresses fatty liver formation accompanied by an up-regulation of β-oxidation in Zucker fatty rats. Biochim Biophys Acta 2005, 1733:224-231.
    • (2005) Biochim Biophys Acta , vol.1733 , pp. 224-231
    • Murase, T.1    Aoki, M.2    Tokimitsu, I.3
  • 69
    • 0026577373 scopus 로고
    • Characterization of the insulinotropic potency of polyunsaturated fatty acids
    • Opara E.C., Hubbard V.S., Burch W.M., Akwari O.E. Characterization of the insulinotropic potency of polyunsaturated fatty acids. Endocrinology 1992, 130:657-662.
    • (1992) Endocrinology , vol.130 , pp. 657-662
    • Opara, E.C.1    Hubbard, V.S.2    Burch, W.M.3    Akwari, O.E.4
  • 71
    • 44349114452 scopus 로고    scopus 로고
    • Administration of perilla oil coated with Calshell increases glucagon-like peptide secretion
    • Adachi T., Yanaka H., Kanai H., Nozaki M., Takahara Y., Tsuda M., et al. Administration of perilla oil coated with Calshell increases glucagon-like peptide secretion. Biol Pharm Bull 2008, 31:1021-1023.
    • (2008) Biol Pharm Bull , vol.31 , pp. 1021-1023
    • Adachi, T.1    Yanaka, H.2    Kanai, H.3    Nozaki, M.4    Takahara, Y.5    Tsuda, M.6
  • 72
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio L.L., Drucker D.J. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007, 132:2131-2157.
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 73
    • 72249113386 scopus 로고    scopus 로고
    • Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice
    • Moriya R., Shirakura T., Ito J., Mashiko S., Seo T. Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice. Am J Physiol Endocrinol Metab 2009, 297:E1358-E1365.
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , pp. E1358-E1365
    • Moriya, R.1    Shirakura, T.2    Ito, J.3    Mashiko, S.4    Seo, T.5
  • 74
    • 84555186977 scopus 로고    scopus 로고
    • +-d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion
    • +-d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes 2012, 61:187-196.
    • (2012) Diabetes , vol.61 , pp. 187-196
    • Gorboulev, V.1    Schürmann, A.2    Vallon, V.3    Kipp, H.4    Jaschke, A.5    Klessen, D.6
  • 75
    • 84893140500 scopus 로고    scopus 로고
    • Short-chain fatty acid receptor and its contribution to glucagon-like peptide-1 release
    • Kaji I., Karaki S., Kuwahara A. Short-chain fatty acid receptor and its contribution to glucagon-like peptide-1 release. Digestion 2014, 89:31-36.
    • (2014) Digestion , vol.89 , pp. 31-36
    • Kaji, I.1    Karaki, S.2    Kuwahara, A.3
  • 76
    • 84875054928 scopus 로고    scopus 로고
    • Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1
    • Xiong Y., Swaminath G., Cao Q., Yang L., Guo Q., Salomonis H., et al. Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1. Mol Cell Endocrinol 2013, 369:119-129.
    • (2013) Mol Cell Endocrinol , vol.369 , pp. 119-129
    • Xiong, Y.1    Swaminath, G.2    Cao, Q.3    Yang, L.4    Guo, Q.5    Salomonis, H.6
  • 78
    • 78349238941 scopus 로고    scopus 로고
    • Pancreatic beta cell lines and their applications in diabetes mellitus research
    • Skelin M., Rupnik M., Cencic A. Pancreatic beta cell lines and their applications in diabetes mellitus research. ALTEX 2010, 27:105-113.
    • (2010) ALTEX , vol.27 , pp. 105-113
    • Skelin, M.1    Rupnik, M.2    Cencic, A.3
  • 79
    • 84860250275 scopus 로고    scopus 로고
    • Long-term in vitro treatment of INS-1 rat pancreatic β-cells by unsaturated free fatty acids protects cells against gluco- and lipotoxicities via activation of GPR40 receptors
    • Tuo Y., Feng D.D., Wang D.F., Sun J., Li S.B., Chen C. Long-term in vitro treatment of INS-1 rat pancreatic β-cells by unsaturated free fatty acids protects cells against gluco- and lipotoxicities via activation of GPR40 receptors. Clin Exp Pharmacol Physiol 2012, 39:423-428.
    • (2012) Clin Exp Pharmacol Physiol , vol.39 , pp. 423-428
    • Tuo, Y.1    Feng, D.D.2    Wang, D.F.3    Sun, J.4    Li, S.B.5    Chen, C.6
  • 80
    • 84895825811 scopus 로고    scopus 로고
    • Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion
    • Paulsen S.J., Larsen L.K., Hansen G., Chelur S., Larsen P.J., Vrang N. Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion. PLoS One 2014, 9:e88227.
    • (2014) PLoS One , vol.9 , pp. e88227
    • Paulsen, S.J.1    Larsen, L.K.2    Hansen, G.3    Chelur, S.4    Larsen, P.J.5    Vrang, N.6
  • 81
    • 85027951651 scopus 로고    scopus 로고
    • Roles of alpha-linolenic acid on IGF-I secretion and GH/IGF system gene expression in porcine primary hepatocytes
    • Fang X.L., Shu G., Zhang Z.Q., Wang S.B., Zhu X.T., Gao P., et al. Roles of alpha-linolenic acid on IGF-I secretion and GH/IGF system gene expression in porcine primary hepatocytes. Mol Biol Rep 2012, 39:10987-10996.
    • (2012) Mol Biol Rep , vol.39 , pp. 10987-10996
    • Fang, X.L.1    Shu, G.2    Zhang, Z.Q.3    Wang, S.B.4    Zhu, X.T.5    Gao, P.6
  • 82
    • 85047690242 scopus 로고    scopus 로고
    • The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity
    • Clemmons D.R. The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity. J Clin Invest 2004, 113:25-27.
    • (2004) J Clin Invest , vol.113 , pp. 25-27
    • Clemmons, D.R.1
  • 83
    • 84880617689 scopus 로고    scopus 로고
    • Eicosapentaenoic acid improves insulin sensitivity and blood sugar in overweight type 2 diabetes mellitus patients: a double-blind randomised clinical trial
    • Sarbolouki S., Javanbakht M.H., Derakhshanian H., Hosseinzadeh P., Zareei M., Hashemi S.B., et al. Eicosapentaenoic acid improves insulin sensitivity and blood sugar in overweight type 2 diabetes mellitus patients: a double-blind randomised clinical trial. Singapore Med J 2013, 54:387-390.
    • (2013) Singapore Med J , vol.54 , pp. 387-390
    • Sarbolouki, S.1    Javanbakht, M.H.2    Derakhshanian, H.3    Hosseinzadeh, P.4    Zareei, M.5    Hashemi, S.B.6
  • 84
    • 84880335323 scopus 로고    scopus 로고
    • Eicosapentaenoic acid-enriched phospholipid ameliorates insulin resistance and lipid metabolism in diet-induced-obese mice
    • Liu X., Xue Y., Liu C., Lou Q., Wang J., Yanagita T., et al. Eicosapentaenoic acid-enriched phospholipid ameliorates insulin resistance and lipid metabolism in diet-induced-obese mice. Lipids Health Dis 2013, 12:109.
    • (2013) Lipids Health Dis , vol.12 , pp. 109
    • Liu, X.1    Xue, Y.2    Liu, C.3    Lou, Q.4    Wang, J.5    Yanagita, T.6
  • 85
    • 0032820327 scopus 로고    scopus 로고
    • Effect of highly purified eicosapentaenoic acid ethyl ester on insulin resistance and hypertension in Dahl salt-sensitive rats
    • Mori Y., Murakawa Y., Yokoyama J., Tajima N., Ikeda Y., Nobukata H., et al. Effect of highly purified eicosapentaenoic acid ethyl ester on insulin resistance and hypertension in Dahl salt-sensitive rats. Metabolism 1999, 48:1089-1095.
    • (1999) Metabolism , vol.48 , pp. 1089-1095
    • Mori, Y.1    Murakawa, Y.2    Yokoyama, J.3    Tajima, N.4    Ikeda, Y.5    Nobukata, H.6
  • 86
    • 13144255675 scopus 로고    scopus 로고
    • Influence of highly purified eicosapentaenoic acid ethyl ester on insulin resistance in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus
    • Mori Y., Murakawa Y., Katoh S., Hata S., Yokoyama J., Tajima N., et al. Influence of highly purified eicosapentaenoic acid ethyl ester on insulin resistance in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus. Metabolism 1997, 46:1458-1464.
    • (1997) Metabolism , vol.46 , pp. 1458-1464
    • Mori, Y.1    Murakawa, Y.2    Katoh, S.3    Hata, S.4    Yokoyama, J.5    Tajima, N.6
  • 87
    • 0034235639 scopus 로고    scopus 로고
    • Long-term administration of highly purified eicosapentaenoic acid ethyl ester prevents diabetes and abnormalities of blood coagulation in male WBN/Kob rats
    • Nobukata H., Ishikawa T., Obata M., Shibutani Y. Long-term administration of highly purified eicosapentaenoic acid ethyl ester prevents diabetes and abnormalities of blood coagulation in male WBN/Kob rats. Metabolism 2000, 49:912-919.
    • (2000) Metabolism , vol.49 , pp. 912-919
    • Nobukata, H.1    Ishikawa, T.2    Obata, M.3    Shibutani, Y.4
  • 88
    • 84875855775 scopus 로고    scopus 로고
    • The role of n-3 polyunsaturated fatty acids in human heart failure
    • Poudyal H., Brown L. The role of n-3 polyunsaturated fatty acids in human heart failure. Endocr Metab Immune Disord Drug Targets 2013, 13:105-117.
    • (2013) Endocr Metab Immune Disord Drug Targets , vol.13 , pp. 105-117
    • Poudyal, H.1    Brown, L.2
  • 89
    • 84864949747 scopus 로고    scopus 로고
    • GLUT4 content decreases along with insulin resistance and high levels of inflammatory markers in rats with metabolic syndrome
    • Leguisamo N.M., Lehnen A.M., Machado U.F., Okamoto M.M., Markoski M.M., Pinto G.H., et al. GLUT4 content decreases along with insulin resistance and high levels of inflammatory markers in rats with metabolic syndrome. Cardiovasc Diabetol 2012, 11:100.
    • (2012) Cardiovasc Diabetol , vol.11 , pp. 100
    • Leguisamo, N.M.1    Lehnen, A.M.2    Machado, U.F.3    Okamoto, M.M.4    Markoski, M.M.5    Pinto, G.H.6
  • 90
    • 33947378695 scopus 로고    scopus 로고
    • Transcriptional regulation of the GLUT4 gene: from PPAR-gamma and FOXO1 to FFA and inflammation
    • Armoni M., Harel C., Karnieli E. Transcriptional regulation of the GLUT4 gene: from PPAR-gamma and FOXO1 to FFA and inflammation. Trends Endocrinol Metab 2007, 18:100-107.
    • (2007) Trends Endocrinol Metab , vol.18 , pp. 100-107
    • Armoni, M.1    Harel, C.2    Karnieli, E.3
  • 91
    • 34247558036 scopus 로고    scopus 로고
    • Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high-fat-fed rats: role of apoptosis, adiponectin and tumour necrosis factor-α
    • Perez-Matute P., Perez-Echarri N., Martinez J.A., Marti A., Moreno-Aliaga M.J. Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high-fat-fed rats: role of apoptosis, adiponectin and tumour necrosis factor-α. Br J Nutr 2007, 97:389-398.
    • (2007) Br J Nutr , vol.97 , pp. 389-398
    • Perez-Matute, P.1    Perez-Echarri, N.2    Martinez, J.A.3    Marti, A.4    Moreno-Aliaga, M.J.5
  • 92
    • 84891364595 scopus 로고    scopus 로고
    • Eicosapentaenoic acid modifies cytokine activity and inhibits cell proliferation in an oesophageal cancer cell line
    • Kubota H., Matsumoto H., Higashida M., Murakami H., Nakashima H., Oka Y., et al. Eicosapentaenoic acid modifies cytokine activity and inhibits cell proliferation in an oesophageal cancer cell line. Anticancer Res 2013, 33:4319-4324.
    • (2013) Anticancer Res , vol.33 , pp. 4319-4324
    • Kubota, H.1    Matsumoto, H.2    Higashida, M.3    Murakami, H.4    Nakashima, H.5    Oka, Y.6
  • 93
    • 80052693613 scopus 로고    scopus 로고
    • Comparison of the effects of the n-3 polyunsaturated fatty acid eicosapentaenoic and fenofibrate on the inhibitory effect of arthritis on IGF1
    • Castillero E., Lopez-Menduina M., Martin A.I., Villanua M.A., Lopez-Calderon A. Comparison of the effects of the n-3 polyunsaturated fatty acid eicosapentaenoic and fenofibrate on the inhibitory effect of arthritis on IGF1. J Endocrinol 2011, 210:361-368.
    • (2011) J Endocrinol , vol.210 , pp. 361-368
    • Castillero, E.1    Lopez-Menduina, M.2    Martin, A.I.3    Villanua, M.A.4    Lopez-Calderon, A.5
  • 94
  • 95
    • 47949094965 scopus 로고    scopus 로고
    • Integration of metabolism and inflammation by lipid-activated nuclear receptors
    • Bensinger S.J., Tontonoz P. Integration of metabolism and inflammation by lipid-activated nuclear receptors. Nature 2008, 454:470-477.
    • (2008) Nature , vol.454 , pp. 470-477
    • Bensinger, S.J.1    Tontonoz, P.2
  • 96
    • 0033779728 scopus 로고    scopus 로고
    • PPAR γ and the treatment of insulin resistance
    • Olefsky J.M., Saltiel A.R. PPAR γ and the treatment of insulin resistance. Trends Endocrinol Metab 2000, 11:362-368.
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 362-368
    • Olefsky, J.M.1    Saltiel, A.R.2
  • 98
    • 20844440063 scopus 로고    scopus 로고
    • EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: evidence for a PPAR-γ-dependent mechanism
    • Li H., Ruan X.Z., Powis S.H., Fernando R., Mon W.Y., Wheeler D.C., et al. EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: evidence for a PPAR-γ-dependent mechanism. Kidney Int 2005, 67:867-874.
    • (2005) Kidney Int , vol.67 , pp. 867-874
    • Li, H.1    Ruan, X.Z.2    Powis, S.H.3    Fernando, R.4    Mon, W.Y.5    Wheeler, D.C.6
  • 99
    • 38949108301 scopus 로고    scopus 로고
    • PPARγ1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells
    • Allred C.D., Talbert D.R., Southard R.C., Wang X., Kilgore M.W. PPARγ1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells. J Nutr 2008, 138:250-256.
    • (2008) J Nutr , vol.138 , pp. 250-256
    • Allred, C.D.1    Talbert, D.R.2    Southard, R.C.3    Wang, X.4    Kilgore, M.W.5
  • 100
    • 33845549418 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid (EPA) on adiponectin gene expression and secretion in primary cultured rat adipocytes
    • Lorente-Cebrian S., Perez-Matute P., Martinez J.A., Marti A., Moreno-Aliaga M.J. Effects of eicosapentaenoic acid (EPA) on adiponectin gene expression and secretion in primary cultured rat adipocytes. J Physiol Biochem 2006, 62:61-69.
    • (2006) J Physiol Biochem , vol.62 , pp. 61-69
    • Lorente-Cebrian, S.1    Perez-Matute, P.2    Martinez, J.A.3    Marti, A.4    Moreno-Aliaga, M.J.5
  • 101
    • 0034743328 scopus 로고    scopus 로고
    • Diabetic KKAy mice exhibit increased hepatic PPARγ1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones
    • Bedoucha M., Atzpodien E., Boelsterli U.A. Diabetic KKAy mice exhibit increased hepatic PPARγ1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones. J Hepatol 2001, 35:17-23.
    • (2001) J Hepatol , vol.35 , pp. 17-23
    • Bedoucha, M.1    Atzpodien, E.2    Boelsterli, U.A.3
  • 102
    • 84864667256 scopus 로고    scopus 로고
    • Intraperitoneal administration attenuates thiazolidinedione-induced hepatic steatosis in KKAy mice with increased hepatic peroxisome proliferator-activated receptor (PPAR)γ mRNA expression
    • Oribe J., Kakuma T., Haranaka M., Okamoto K., Seike M., Yoshimatsu H. Intraperitoneal administration attenuates thiazolidinedione-induced hepatic steatosis in KKAy mice with increased hepatic peroxisome proliferator-activated receptor (PPAR)γ mRNA expression. Obes Res Clin Pract 2012, 6:e175-e262.
    • (2012) Obes Res Clin Pract , vol.6 , pp. e175-e262
    • Oribe, J.1    Kakuma, T.2    Haranaka, M.3    Okamoto, K.4    Seike, M.5    Yoshimatsu, H.6
  • 103
    • 84899494559 scopus 로고    scopus 로고
    • Effects and potential mechanisms of pioglitazone on lipid metabolism in obese diabetic KKAy mice
    • Peng J., Huan Y., Jiang Q., Sun S.-J., Jia C.-M., Shen Z.-F. Effects and potential mechanisms of pioglitazone on lipid metabolism in obese diabetic KKAy mice. PPAR Res 2014, 2014:538183.
    • (2014) PPAR Res , vol.2014 , pp. 538183
    • Peng, J.1    Huan, Y.2    Jiang, Q.3    Sun, S.-J.4    Jia, C.-M.5    Shen, Z.-F.6
  • 104
    • 52749087214 scopus 로고    scopus 로고
    • Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets
    • Kato T., Shimano H., Yamamoto T., Ishikawa M., Kumadaki S., Matsuzaka T., et al. Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets. Diabetes 2008, 57:2382-2392.
    • (2008) Diabetes , vol.57 , pp. 2382-2392
    • Kato, T.1    Shimano, H.2    Yamamoto, T.3    Ishikawa, M.4    Kumadaki, S.5    Matsuzaka, T.6
  • 105
    • 78651323561 scopus 로고    scopus 로고
    • SREBP-1c, Pdx-1, and GLP-1R involved in palmitate-EPA regulated glucose-stimulated insulin secretion in INS-1 cells
    • Shao S., Liu Z., Yang Y., Zhang M., Yu X. SREBP-1c, Pdx-1, and GLP-1R involved in palmitate-EPA regulated glucose-stimulated insulin secretion in INS-1 cells. J Cell Biochem 2010, 111:634-642.
    • (2010) J Cell Biochem , vol.111 , pp. 634-642
    • Shao, S.1    Liu, Z.2    Yang, Y.3    Zhang, M.4    Yu, X.5
  • 106
    • 84892400720 scopus 로고    scopus 로고
    • Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle
    • Bertrand C., Pignalosa A., Wanecq E., Rancoule C., Batut A., Deleruyelle S., et al. Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle. PLoS One 2013, 8:e78874.
    • (2013) PLoS One , vol.8 , pp. e78874
    • Bertrand, C.1    Pignalosa, A.2    Wanecq, E.3    Rancoule, C.4    Batut, A.5    Deleruyelle, S.6
  • 107
    • 0029797469 scopus 로고    scopus 로고
    • Eicosapentaenoic acid (C20:5) augments glucose-induced insulin secretion from β-TC3 insulinoma cells
    • Konard R.J., Stoller J.Z., Gao Z.Y., Wolf B.A. Eicosapentaenoic acid (C20:5) augments glucose-induced insulin secretion from β-TC3 insulinoma cells. Pancreas 1996, 13:253-258.
    • (1996) Pancreas , vol.13 , pp. 253-258
    • Konard, R.J.1    Stoller, J.Z.2    Gao, Z.Y.3    Wolf, B.A.4
  • 108
    • 72949111358 scopus 로고    scopus 로고
    • Apelin inhibits insulin secretion in pancreatic β-cells by activation of PI3-kinase-phosphodiesterase 3B
    • Guo L., Li Q., Wang W., Yu P., Pan H., Li P., et al. Apelin inhibits insulin secretion in pancreatic β-cells by activation of PI3-kinase-phosphodiesterase 3B. Endocr Res 2009, 34:142-154.
    • (2009) Endocr Res , vol.34 , pp. 142-154
    • Guo, L.1    Li, Q.2    Wang, W.3    Yu, P.4    Pan, H.5    Li, P.6
  • 109
    • 54849424539 scopus 로고    scopus 로고
    • Apelin stimulates glucose utilization in normal and obese insulin-resistant mice
    • Dray C., Knauf C., Daviaud D., Waget A., Boucher J., Buleon M., et al. Apelin stimulates glucose utilization in normal and obese insulin-resistant mice. Cell Metab 2008, 8:437-445.
    • (2008) Cell Metab , vol.8 , pp. 437-445
    • Dray, C.1    Knauf, C.2    Daviaud, D.3    Waget, A.4    Boucher, J.5    Buleon, M.6
  • 110
    • 56349100059 scopus 로고    scopus 로고
    • Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion
    • Morishita M., Tanaka T., Shida T., Takayama K. Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion. J Control Release 2008, 132:99-104.
    • (2008) J Control Release , vol.132 , pp. 99-104
    • Morishita, M.1    Tanaka, T.2    Shida, T.3    Takayama, K.4
  • 111
    • 83055184091 scopus 로고    scopus 로고
    • 5-Hydroxy-eicosapentaenoic acid is an endogenous GPR119 agonist and enhances glucose-dependent insulin secretion
    • Kogure R., Toyama K., Hiyamuta S., Kojima I., Takeda S. 5-Hydroxy-eicosapentaenoic acid is an endogenous GPR119 agonist and enhances glucose-dependent insulin secretion. Biochem Biophys Res Commun 2011, 416:58-63.
    • (2011) Biochem Biophys Res Commun , vol.416 , pp. 58-63
    • Kogure, R.1    Toyama, K.2    Hiyamuta, S.3    Kojima, I.4    Takeda, S.5
  • 112
    • 0031005695 scopus 로고    scopus 로고
    • Docosahexanoic acid (DHA) improved glucose and lipid metabolism in KK-Ay mice with genetic non-insulin-dependent diabetes mellitus (NIDDM)
    • Shimura T., Miura T., Usami M., Ishihara E., Tanigawa K., Ishida H., et al. Docosahexanoic acid (DHA) improved glucose and lipid metabolism in KK-Ay mice with genetic non-insulin-dependent diabetes mellitus (NIDDM). Biol Pharm Bull 1997, 20:507-510.
    • (1997) Biol Pharm Bull , vol.20 , pp. 507-510
    • Shimura, T.1    Miura, T.2    Usami, M.3    Ishihara, E.4    Tanigawa, K.5    Ishida, H.6
  • 113
    • 36749024519 scopus 로고    scopus 로고
    • Docosahexaenoic acid (DHA) but not eicosapentaenoic acid (EPA) prevents trans-10, cis-12 conjugated linoleic acid (CLA)-induced insulin resistance in mice
    • Vemuri M., Kelley D.S., Mackey B.E., Rasooly R., Bartolini G. Docosahexaenoic acid (DHA) but not eicosapentaenoic acid (EPA) prevents trans-10, cis-12 conjugated linoleic acid (CLA)-induced insulin resistance in mice. Metab Syndr Relat Disord 2007, 5:315-322.
    • (2007) Metab Syndr Relat Disord , vol.5 , pp. 315-322
    • Vemuri, M.1    Kelley, D.S.2    Mackey, B.E.3    Rasooly, R.4    Bartolini, G.5
  • 114
    • 84865086635 scopus 로고    scopus 로고
    • Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA
    • Oliver E., McGillicuddy F.C., Harford K.A., Reynolds C.M., Phillips C.M., Ferguson J.F., et al. Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA. J Nutr Biochem 2012, 23:1192-1200.
    • (2012) J Nutr Biochem , vol.23 , pp. 1192-1200
    • Oliver, E.1    McGillicuddy, F.C.2    Harford, K.A.3    Reynolds, C.M.4    Phillips, C.M.5    Ferguson, J.F.6
  • 115
    • 73949159619 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRα
    • Howell G., Deng X., Yellaturu C., Park E.A., Wilcox H.G., Raghow R., et al. N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRα. Biochim Biophys Acta 2009, 1791:1190-1196.
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 1190-1196
    • Howell, G.1    Deng, X.2    Yellaturu, C.3    Park, E.A.4    Wilcox, H.G.5    Raghow, R.6
  • 116
    • 79961082162 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase: a vital checkpoint in the development and progression of obesity
    • Poudyal H., Brown L. Stearoyl-CoA desaturase: a vital checkpoint in the development and progression of obesity. Endocr Metab Immune Disord Drug Targets 2011, 11:217-231.
    • (2011) Endocr Metab Immune Disord Drug Targets , vol.11 , pp. 217-231
    • Poudyal, H.1    Brown, L.2
  • 117
    • 84877590178 scopus 로고    scopus 로고
    • Colonic delivery of docosahexaenoic acid improves impaired glucose tolerance via GLP-1 secretion and suppresses pancreatic islet hyperplasia in diabetic KK-A(y) mice
    • Shida T., Kamei N., Takeda-Morishita M., Isowa K., Takayama K. Colonic delivery of docosahexaenoic acid improves impaired glucose tolerance via GLP-1 secretion and suppresses pancreatic islet hyperplasia in diabetic KK-A(y) mice. Int J Pharm 2013, 450:63-69.
    • (2013) Int J Pharm , vol.450 , pp. 63-69
    • Shida, T.1    Kamei, N.2    Takeda-Morishita, M.3    Isowa, K.4    Takayama, K.5
  • 118
    • 13444263540 scopus 로고    scopus 로고
    • Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
    • Hirasawa A., Tsumaya K., Awaji T., Katsuma S., Adachi T., Yamada M., et al. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 2005, 11:90-94.
    • (2005) Nat Med , vol.11 , pp. 90-94
    • Hirasawa, A.1    Tsumaya, K.2    Awaji, T.3    Katsuma, S.4    Adachi, T.5    Yamada, M.6
  • 119
    • 0141448772 scopus 로고    scopus 로고
    • Adipokines, inflammation, and the endothelium in diabetes
    • Aldhahi W., Hamdy O. Adipokines, inflammation, and the endothelium in diabetes. Curr Diab Rep 2003, 3:293-298.
    • (2003) Curr Diab Rep , vol.3 , pp. 293-298
    • Aldhahi, W.1    Hamdy, O.2
  • 121
    • 84875529964 scopus 로고    scopus 로고
    • Metabolic syndrome and inflammation: a critical review of in vitro and clinical approaches for benefit assessment of plant food supplements
    • Di Lorenzo C., Dell'agli M., Colombo E., Sangiovanni E., Restani P. Metabolic syndrome and inflammation: a critical review of in vitro and clinical approaches for benefit assessment of plant food supplements. Evid Based Complement Alternat Med 2013, 2013:782461.
    • (2013) Evid Based Complement Alternat Med , vol.2013 , pp. 782461
    • Di Lorenzo, C.1    Dell'agli, M.2    Colombo, E.3    Sangiovanni, E.4    Restani, P.5
  • 122
    • 0029866219 scopus 로고    scopus 로고
    • Control of endothelial leukocyte adhesion molecules by fatty acids
    • [Suppl]
    • De Caterina R., Libby P. Control of endothelial leukocyte adhesion molecules by fatty acids. Lipids 1996, 31:S57-S63. [Suppl].
    • (1996) Lipids , vol.31 , pp. S57-S63
    • De Caterina, R.1    Libby, P.2
  • 123
    • 0031409193 scopus 로고    scopus 로고
    • Docosahexaenoic and eicosapentaenoic acids inhibit in vitro human endothelial cell production of interleukin-6
    • Khalfoun B., Thibault F., Watier H., Bardos P., Lebranchu Y. Docosahexaenoic and eicosapentaenoic acids inhibit in vitro human endothelial cell production of interleukin-6. Adv Exp Med Biol 1997, 400B:589-597.
    • (1997) Adv Exp Med Biol , vol.400 B , pp. 589-597
    • Khalfoun, B.1    Thibault, F.2    Watier, H.3    Bardos, P.4    Lebranchu, Y.5
  • 124
    • 0030038986 scopus 로고    scopus 로고
    • The effect on human tumor necrosis factor α and interleukin 1 β production of diets enriched in n-3 fatty acids from vegetable oil or fish oil
    • Caughey G.E., Mantzioris E., Gibson R.A., Cleland L.G., James M.J. The effect on human tumor necrosis factor α and interleukin 1 β production of diets enriched in n-3 fatty acids from vegetable oil or fish oil. Am J Clin Nutr 1996, 63:116-122.
    • (1996) Am J Clin Nutr , vol.63 , pp. 116-122
    • Caughey, G.E.1    Mantzioris, E.2    Gibson, R.A.3    Cleland, L.G.4    James, M.J.5
  • 125
    • 0031900287 scopus 로고    scopus 로고
    • Dietary α-linolenic acid increases TNF-α, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice
    • Chavali S.R., Zhong W.W., Forse R.A. Dietary α-linolenic acid increases TNF-α, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice. Prostaglandins Leukot Essent Fatty Acids 1998, 58:185-191.
    • (1998) Prostaglandins Leukot Essent Fatty Acids , vol.58 , pp. 185-191
    • Chavali, S.R.1    Zhong, W.W.2    Forse, R.A.3
  • 126
    • 84655174598 scopus 로고    scopus 로고
    • (n-3) Fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights
    • Kalupahana N.S., Claycombe K.J., Moustaid-Moussa N. (n-3) Fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights. Adv Nutr 2011, 2:304-316.
    • (2011) Adv Nutr , vol.2 , pp. 304-316
    • Kalupahana, N.S.1    Claycombe, K.J.2    Moustaid-Moussa, N.3
  • 127
  • 128
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky J.M., Glass C.K. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 2010, 72:219-246.
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 130
    • 38949106690 scopus 로고    scopus 로고
    • Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases
    • Tilg H., Moschen A.R. Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases. Clin Sci (Lond) 2008, 114:275-288.
    • (2008) Clin Sci (Lond) , vol.114 , pp. 275-288
    • Tilg, H.1    Moschen, A.R.2
  • 131
  • 132
    • 60149088612 scopus 로고    scopus 로고
    • Inflammation in obesity-related diseases
    • O'Rourke R.W. Inflammation in obesity-related diseases. Surgery 2009, 145:255-259.
    • (2009) Surgery , vol.145 , pp. 255-259
    • O'Rourke, R.W.1
  • 133
    • 84903474732 scopus 로고    scopus 로고
    • Role of anti-inflammatory adipokines in obesity-related diseases
    • Ohashi K., Shibata R., Murohara T., Ouchi N. Role of anti-inflammatory adipokines in obesity-related diseases. Trends Endocrinol Metab 2014, 25:348-355.
    • (2014) Trends Endocrinol Metab , vol.25 , pp. 348-355
    • Ohashi, K.1    Shibata, R.2    Murohara, T.3    Ouchi, N.4
  • 134
    • 84897114276 scopus 로고    scopus 로고
    • Adipokines - removing road blocks to obesity and diabetes therapy
    • Bluher M. Adipokines - removing road blocks to obesity and diabetes therapy. Mol Metab 2014, 3:230-240.
    • (2014) Mol Metab , vol.3 , pp. 230-240
    • Bluher, M.1
  • 135
    • 0030013679 scopus 로고    scopus 로고
    • Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men
    • Segal K.R., Landt M., Klein S. Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. Diabetes 1996, 45:988-991.
    • (1996) Diabetes , vol.45 , pp. 988-991
    • Segal, K.R.1    Landt, M.2    Klein, S.3
  • 136
    • 78049513522 scopus 로고    scopus 로고
    • Weight regain after a diet-induced loss is predicted by higher baseline leptin and lower ghrelin plasma levels
    • Crujeiras A.B., Goyenechea E., Abete I., Lage M., Carreira M.C., Martinez J.A., et al. Weight regain after a diet-induced loss is predicted by higher baseline leptin and lower ghrelin plasma levels. J Clin Endocrinol Metab 2010, 95:5037-5044.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 5037-5044
    • Crujeiras, A.B.1    Goyenechea, E.2    Abete, I.3    Lage, M.4    Carreira, M.C.5    Martinez, J.A.6
  • 138
    • 0031606279 scopus 로고    scopus 로고
    • Chronic leptin infusion increases arterial pressure
    • Shek E.W., Brands M.W., Hall J.E. Chronic leptin infusion increases arterial pressure. Hypertension 1998, 31:409-414.
    • (1998) Hypertension , vol.31 , pp. 409-414
    • Shek, E.W.1    Brands, M.W.2    Hall, J.E.3
  • 140
    • 1842484296 scopus 로고    scopus 로고
    • AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
    • Minokoshi Y., Alquier T., Furukawa N., Kim Y.B., Lee A., Xue B., et al. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004, 428:569-574.
    • (2004) Nature , vol.428 , pp. 569-574
    • Minokoshi, Y.1    Alquier, T.2    Furukawa, N.3    Kim, Y.B.4    Lee, A.5    Xue, B.6
  • 141
    • 34548362074 scopus 로고    scopus 로고
    • Hypothalamic leptin regulation of energy homeostasis and glucose metabolism
    • Morton G.J. Hypothalamic leptin regulation of energy homeostasis and glucose metabolism. J Physiol 2007, 583:437-443.
    • (2007) J Physiol , vol.583 , pp. 437-443
    • Morton, G.J.1
  • 142
    • 0032904873 scopus 로고    scopus 로고
    • Comparing effects of leptin and insulin on glucose metabolism in skeletal muscle: evidence for an effect of leptin on glucose uptake and decarboxylation
    • Ceddia R.B., William W.N., Curi R. Comparing effects of leptin and insulin on glucose metabolism in skeletal muscle: evidence for an effect of leptin on glucose uptake and decarboxylation. Int J Obes Relat Metab Disord 1999, 23:75-82.
    • (1999) Int J Obes Relat Metab Disord , vol.23 , pp. 75-82
    • Ceddia, R.B.1    William, W.N.2    Curi, R.3
  • 143
    • 0032971214 scopus 로고    scopus 로고
    • Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats
    • Minokoshi Y., Haque M.S., Shimazu T. Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats. Diabetes 1999, 48:287-291.
    • (1999) Diabetes , vol.48 , pp. 287-291
    • Minokoshi, Y.1    Haque, M.S.2    Shimazu, T.3
  • 144
    • 0030965884 scopus 로고    scopus 로고
    • Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
    • Emilsson V., Liu Y.L., Cawthorne M.A., Morton N.M., Davenport M. Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 1997, 46:313-316.
    • (1997) Diabetes , vol.46 , pp. 313-316
    • Emilsson, V.1    Liu, Y.L.2    Cawthorne, M.A.3    Morton, N.M.4    Davenport, M.5
  • 146
    • 33746886648 scopus 로고    scopus 로고
    • Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice
    • Ueno N., Inui A., Kalra P.S., Kalra S.P. Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice. Peptides 2006, 27:2332-2342.
    • (2006) Peptides , vol.27 , pp. 2332-2342
    • Ueno, N.1    Inui, A.2    Kalra, P.S.3    Kalra, S.P.4
  • 147
    • 18344374382 scopus 로고    scopus 로고
    • Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats
    • Hidaka S., Yoshimatsu H., Kondou S., Tsuruta Y., Oka K., Noguchi H., et al. Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats. FASEB J 2002, 16:509-518.
    • (2002) FASEB J , vol.16 , pp. 509-518
    • Hidaka, S.1    Yoshimatsu, H.2    Kondou, S.3    Tsuruta, Y.4    Oka, K.5    Noguchi, H.6
  • 148
    • 1642441980 scopus 로고    scopus 로고
    • Chronic leptin treatment enhances insulin-stimulated glucose disposal in skeletal muscle of high-fat fed rodents
    • Yaspelkis B.B., Singh M.K., Krisan A.D., Collins D.E., Kwong C.C., Bernard J.R., et al. Chronic leptin treatment enhances insulin-stimulated glucose disposal in skeletal muscle of high-fat fed rodents. Life Sci 2004, 74:1801-1816.
    • (2004) Life Sci , vol.74 , pp. 1801-1816
    • Yaspelkis, B.B.1    Singh, M.K.2    Krisan, A.D.3    Collins, D.E.4    Kwong, C.C.5    Bernard, J.R.6
  • 149
    • 0030895726 scopus 로고    scopus 로고
    • Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect
    • Berti L., Kellerer M., Capp E., Haring H.U. Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect. Diabetologia 1997, 40:606-609.
    • (1997) Diabetologia , vol.40 , pp. 606-609
    • Berti, L.1    Kellerer, M.2    Capp, E.3    Haring, H.U.4
  • 150
    • 84855486959 scopus 로고    scopus 로고
    • Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice
    • Sainz N., Rodriguez A., Catalan V., Becerril S., Ramirez B., Lancha A., et al. Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice. PLoS One 2012, 7:e29389.
    • (2012) PLoS One , vol.7 , pp. e29389
    • Sainz, N.1    Rodriguez, A.2    Catalan, V.3    Becerril, S.4    Ramirez, B.5    Lancha, A.6
  • 151
    • 33645883249 scopus 로고    scopus 로고
    • Insulin and leptin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3-kinase-dependent mechanism
    • Benomar Y., Naour N., Aubourg A., Bailleux V., Gertler A., Djiane J., et al. Insulin and leptin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3-kinase-dependent mechanism. Endocrinology 2006, 147:2550-2556.
    • (2006) Endocrinology , vol.147 , pp. 2550-2556
    • Benomar, Y.1    Naour, N.2    Aubourg, A.3    Bailleux, V.4    Gertler, A.5    Djiane, J.6
  • 152
    • 84863753016 scopus 로고    scopus 로고
    • Effects of an in-patient treatment program based on regular exercise and a balanced diet on high molecular weight adiponectin, resistin levels, and insulin resistance in adolescents with severe obesity
    • Gueugnon C., Mougin F., Simon-Rigaud M.L., Regnard J., Negre V., Dumoulin G. Effects of an in-patient treatment program based on regular exercise and a balanced diet on high molecular weight adiponectin, resistin levels, and insulin resistance in adolescents with severe obesity. Appl Physiol Nutr Metab 2012, 37:672-679.
    • (2012) Appl Physiol Nutr Metab , vol.37 , pp. 672-679
    • Gueugnon, C.1    Mougin, F.2    Simon-Rigaud, M.L.3    Regnard, J.4    Negre, V.5    Dumoulin, G.6
  • 153
    • 0034096988 scopus 로고    scopus 로고
    • Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
    • Hotta K., Funahashi T., Arita Y., Takahashi M., Matsuda M., Okamoto Y., et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000, 20:1595-1599.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1595-1599
    • Hotta, K.1    Funahashi, T.2    Arita, Y.3    Takahashi, M.4    Matsuda, M.5    Okamoto, Y.6
  • 154
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • Kadowaki T., Yamauchi T., Kubota N., Hara K., Ueki K., Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 2006, 116:1784-1792.
    • (2006) J Clin Invest , vol.116 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3    Hara, K.4    Ueki, K.5    Tobe, K.6
  • 155
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin
    • Ouchi N., Kihara S., Arita Y., Maeda K., Kuriyama H., Okamoto Y., et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999, 100:2473-2476.
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 156
    • 34248187069 scopus 로고    scopus 로고
    • Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease
    • Menzaghi C., Trischitta V., Doria A. Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease. Diabetes 2007, 56:1198-1209.
    • (2007) Diabetes , vol.56 , pp. 1198-1209
    • Menzaghi, C.1    Trischitta, V.2    Doria, A.3
  • 157
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002, 8:1288-1295.
    • (2002) Nat Med , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3    Ito, Y.4    Waki, H.5    Uchida, S.6
  • 158
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
    • Tomas E., Tsao T.S., Saha A.K., Murrey H.E., Zhang Cc C., Itani S.I., et al. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci U S A 2002, 99:16309-16313.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3    Murrey, H.E.4    Zhang Cc, C.5    Itani, S.I.6
  • 159
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg A.H., Combs T.P., Du X., Brownlee M., Scherer P.E. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001, 7:947-953.
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 160
    • 0035663963 scopus 로고    scopus 로고
    • Endogenous glucose production is inhibited by the adipose-derived protein Acrp30
    • Combs T.P., Berg A.H., Obici S., Scherer P.E., Rossetti L. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J Clin Invest 2001, 108:1875-1881.
    • (2001) J Clin Invest , vol.108 , pp. 1875-1881
    • Combs, T.P.1    Berg, A.H.2    Obici, S.3    Scherer, P.E.4    Rossetti, L.5
  • 161
    • 0037462684 scopus 로고    scopus 로고
    • Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis
    • Yamauchi T., Kamon J., Waki H., Imai Y., Shimozawa N., Hioki K., et al. Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis. J Biol Chem 2003, 278:2461-2468.
    • (2003) J Biol Chem , vol.278 , pp. 2461-2468
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Imai, Y.4    Shimozawa, N.5    Hioki, K.6
  • 162
    • 63849103057 scopus 로고    scopus 로고
    • Role of resistin in insulin sensitivity in rodents and humans
    • Barnes K.M., Miner J.L. Role of resistin in insulin sensitivity in rodents and humans. Curr Protein Pept Sci 2009, 10:96-107.
    • (2009) Curr Protein Pept Sci , vol.10 , pp. 96-107
    • Barnes, K.M.1    Miner, J.L.2
  • 163
    • 24144475705 scopus 로고    scopus 로고
    • Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action
    • Graveleau C., Zaha V.G., Mohajer A., Banerjee R.R., Dudley-Rucker N., Steppan C.M., et al. Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action. J Biol Chem 2005, 280:31679-31685.
    • (2005) J Biol Chem , vol.280 , pp. 31679-31685
    • Graveleau, C.1    Zaha, V.G.2    Mohajer, A.3    Banerjee, R.R.4    Dudley-Rucker, N.5    Steppan, C.M.6
  • 166
    • 1842479689 scopus 로고    scopus 로고
    • Modest weight loss and reduction in waist circumference after medical treatment are associated with favorable changes in serum adipocytokines
    • Valsamakis G., McTernan P.G., Chetty R., Al Daghri N., Field A., Hanif W., et al. Modest weight loss and reduction in waist circumference after medical treatment are associated with favorable changes in serum adipocytokines. Metabolism 2004, 53:430-434.
    • (2004) Metabolism , vol.53 , pp. 430-434
    • Valsamakis, G.1    McTernan, P.G.2    Chetty, R.3    Al Daghri, N.4    Field, A.5    Hanif, W.6
  • 168
    • 70350340829 scopus 로고    scopus 로고
    • High serum resistin level may be an indicator of the severity of coronary disease in acute coronary syndrome
    • Wang H., Chen D.Y., Cao J., He Z.Y., Zhu B.P., Long M. High serum resistin level may be an indicator of the severity of coronary disease in acute coronary syndrome. Chin Med Sci J 2009, 24:161-166.
    • (2009) Chin Med Sci J , vol.24 , pp. 161-166
    • Wang, H.1    Chen, D.Y.2    Cao, J.3    He, Z.Y.4    Zhu, B.P.5    Long, M.6
  • 169
    • 0037241112 scopus 로고    scopus 로고
    • Adipose-derived resistin and gut-derived resistin-like molecule-β selectively impair insulin action on glucose production
    • Rajala M.W., Obici S., Scherer P.E., Rossetti L. Adipose-derived resistin and gut-derived resistin-like molecule-β selectively impair insulin action on glucose production. J Clin Invest 2003, 111:225-230.
    • (2003) J Clin Invest , vol.111 , pp. 225-230
    • Rajala, M.W.1    Obici, S.2    Scherer, P.E.3    Rossetti, L.4
  • 172
    • 70349570571 scopus 로고    scopus 로고
    • Resistin induces insulin resistance by both AMPK-dependent and AMPK-independent mechanisms in HepG2 cells
    • Luo Z., Zhang Y., Li F., He J., Ding H., Yan L., et al. Resistin induces insulin resistance by both AMPK-dependent and AMPK-independent mechanisms in HepG2 cells. Endocrine 2009, 36:60-69.
    • (2009) Endocrine , vol.36 , pp. 60-69
    • Luo, Z.1    Zhang, Y.2    Li, F.3    He, J.4    Ding, H.5    Yan, L.6
  • 173
    • 35549002189 scopus 로고    scopus 로고
    • Nampt/PBEF/Visfatin regulates insulin secretion in β cells as a systemic NAD biosynthetic enzyme
    • Revollo J.R., Korner A., Mills K.F., Satoh A., Wang T., Garten A., et al. Nampt/PBEF/Visfatin regulates insulin secretion in β cells as a systemic NAD biosynthetic enzyme. Cell Metab 2007, 6:363-375.
    • (2007) Cell Metab , vol.6 , pp. 363-375
    • Revollo, J.R.1    Korner, A.2    Mills, K.F.3    Satoh, A.4    Wang, T.5    Garten, A.6
  • 174
    • 25844491778 scopus 로고    scopus 로고
    • Plasma visfatin concentrations and fat depot-specific mRNA expression in humans
    • Berndt J., Kloting N., Kralisch S., Kovacs P., Fasshauer M., Schon M.R., et al. Plasma visfatin concentrations and fat depot-specific mRNA expression in humans. Diabetes 2005, 54:2911-2916.
    • (2005) Diabetes , vol.54 , pp. 2911-2916
    • Berndt, J.1    Kloting, N.2    Kralisch, S.3    Kovacs, P.4    Fasshauer, M.5    Schon, M.R.6
  • 175
    • 33646052892 scopus 로고    scopus 로고
    • Increased plasma visfatin concentrations in morbidly obese subjects are reduced after gastric banding
    • Haider D.G., Schindler K., Schaller G., Prager G., Wolzt M., Ludvik B. Increased plasma visfatin concentrations in morbidly obese subjects are reduced after gastric banding. J Clin Endocrinol Metab 2006, 91:1578-1581.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1578-1581
    • Haider, D.G.1    Schindler, K.2    Schaller, G.3    Prager, G.4    Wolzt, M.5    Ludvik, B.6
  • 177
    • 67649911291 scopus 로고    scopus 로고
    • Influence of visfatin on histopathological changes of non-alcoholic fatty liver disease
    • Aller R., de Luis D.A., Izaola O., Sagrado M.G., Conde R., Velasco M.C., et al. Influence of visfatin on histopathological changes of non-alcoholic fatty liver disease. Dig Dis Sci 2009, 54:1772-1777.
    • (2009) Dig Dis Sci , vol.54 , pp. 1772-1777
    • Aller, R.1    de Luis, D.A.2    Izaola, O.3    Sagrado, M.G.4    Conde, R.5    Velasco, M.C.6
  • 178
    • 33947247655 scopus 로고    scopus 로고
    • Association between plasma visfatin and vascular endothelial function in patients with type 2 diabetes mellitus
    • Takebayashi K., Suetsugu M., Wakabayashi S., Aso Y., Inukai T. Association between plasma visfatin and vascular endothelial function in patients with type 2 diabetes mellitus. Metabolism 2007, 56:451-458.
    • (2007) Metabolism , vol.56 , pp. 451-458
    • Takebayashi, K.1    Suetsugu, M.2    Wakabayashi, S.3    Aso, Y.4    Inukai, T.5
  • 179
    • 30344471828 scopus 로고    scopus 로고
    • Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus
    • Chen M.P., Chung F.M., Chang D.M., Tsai J.C., Huang H.F., Shin S.J., et al. Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 2006, 91:295-299.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 295-299
    • Chen, M.P.1    Chung, F.M.2    Chang, D.M.3    Tsai, J.C.4    Huang, H.F.5    Shin, S.J.6
  • 180
    • 33846930861 scopus 로고    scopus 로고
    • Plasma visfatin levels in patients with newly diagnosed and untreated type 2 diabetes mellitus and impaired glucose tolerance
    • Dogru T., Sonmez A., Tasci I., Bozoglu E., Yilmaz M.I., Genc H., et al. Plasma visfatin levels in patients with newly diagnosed and untreated type 2 diabetes mellitus and impaired glucose tolerance. Diabetes Res Clin Pract 2007, 76:24-29.
    • (2007) Diabetes Res Clin Pract , vol.76 , pp. 24-29
    • Dogru, T.1    Sonmez, A.2    Tasci, I.3    Bozoglu, E.4    Yilmaz, M.I.5    Genc, H.6
  • 181
    • 77955907509 scopus 로고    scopus 로고
    • Resistin and visfatin: regulators of insulin sensitivity, inflammation and immunity
    • Stofkova A. Resistin and visfatin: regulators of insulin sensitivity, inflammation and immunity. Endocr Regul 2010, 44:25-36.
    • (2010) Endocr Regul , vol.44 , pp. 25-36
    • Stofkova, A.1
  • 184
    • 39649100626 scopus 로고    scopus 로고
    • Serum visfatin concentrations in obese adolescents and its correlation with age and high-density lipoprotein cholesterol
    • Jin H., Jiang B., Tang J., Lu W., Wang W., Zhou L., et al. Serum visfatin concentrations in obese adolescents and its correlation with age and high-density lipoprotein cholesterol. Diabetes Res Clin Pract 2008, 79:412-418.
    • (2008) Diabetes Res Clin Pract , vol.79 , pp. 412-418
    • Jin, H.1    Jiang, B.2    Tang, J.3    Lu, W.4    Wang, W.5    Zhou, L.6
  • 185
    • 34548857700 scopus 로고    scopus 로고
    • SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
    • Sun C., Zhang F., Ge X., Yan T., Chen X., Shi X., et al. SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab 2007, 6:307-319.
    • (2007) Cell Metab , vol.6 , pp. 307-319
    • Sun, C.1    Zhang, F.2    Ge, X.3    Yan, T.4    Chen, X.5    Shi, X.6
  • 186
    • 70349849659 scopus 로고    scopus 로고
    • Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity
    • Romacho T., Azcutia V., Vazquez-Bella M., Matesanz N., Cercas E., Nevado J., et al. Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity. Diabetologia 2009, 52:2455-2463.
    • (2009) Diabetologia , vol.52 , pp. 2455-2463
    • Romacho, T.1    Azcutia, V.2    Vazquez-Bella, M.3    Matesanz, N.4    Cercas, E.5    Nevado, J.6
  • 187
    • 67650327064 scopus 로고    scopus 로고
    • Association of plasma visfatin levels with inflammation, atherosclerosis and acute coronary syndromes (ACS) in humans
    • Liu S.W., Qiao S.B., Yuan J.S., Liu D.Q. Association of plasma visfatin levels with inflammation, atherosclerosis and acute coronary syndromes (ACS) in humans. Clin Endocrinol (Oxf) 2009, 71:202-207.
    • (2009) Clin Endocrinol (Oxf) , vol.71 , pp. 202-207
    • Liu, S.W.1    Qiao, S.B.2    Yuan, J.S.3    Liu, D.Q.4
  • 188
    • 49649128362 scopus 로고    scopus 로고
    • Increased serum visfatin in patients with metabolic syndrome and carotid atherosclerosis
    • Zhong M., Tan H.W., Gong H.P., Wang S.F., Zhang Y., Zhang W. Increased serum visfatin in patients with metabolic syndrome and carotid atherosclerosis. Clin Endocrinol (Oxf) 2008, 69:878-884.
    • (2008) Clin Endocrinol (Oxf) , vol.69 , pp. 878-884
    • Zhong, M.1    Tan, H.W.2    Gong, H.P.3    Wang, S.F.4    Zhang, Y.5    Zhang, W.6
  • 189
    • 69149100440 scopus 로고    scopus 로고
    • Elevated visfatin/pre-B-cell colony-enhancing factor plasma concentration in ischemic stroke
    • Lu L.F., Yang S.S., Wang C.P., Hung W.C., Yu T.H., Chiu C.A., et al. Elevated visfatin/pre-B-cell colony-enhancing factor plasma concentration in ischemic stroke. J Stroke Cerebrovasc Dis 2009, 18:354-359.
    • (2009) J Stroke Cerebrovasc Dis , vol.18 , pp. 354-359
    • Lu, L.F.1    Yang, S.S.2    Wang, C.P.3    Hung, W.C.4    Yu, T.H.5    Chiu, C.A.6
  • 190
    • 84899476892 scopus 로고    scopus 로고
    • Extracellular visfatin activates gluconeogenesis in HepG2 cells through the classical PKA/CREB-dependent pathway
    • Choi Y.J., Choi S.E., Ha E.S., Kang Y., Han S.J., Kim D.J., et al. Extracellular visfatin activates gluconeogenesis in HepG2 cells through the classical PKA/CREB-dependent pathway. Horm Metab Res 2014, 46:233-239.
    • (2014) Horm Metab Res , vol.46 , pp. 233-239
    • Choi, Y.J.1    Choi, S.E.2    Ha, E.S.3    Kang, Y.4    Han, S.J.5    Kim, D.J.6
  • 192
    • 84855483237 scopus 로고    scopus 로고
    • Lipid redistribution by α-linolenic acid-rich chia seed inhibits stearoyl-CoA desaturase-1 and induces cardiac and hepatic protection in diet-induced obese rats
    • Poudyal H., Panchal S.K., Waanders J., Ward L., Brown L. Lipid redistribution by α-linolenic acid-rich chia seed inhibits stearoyl-CoA desaturase-1 and induces cardiac and hepatic protection in diet-induced obese rats. J Nutr Biochem 2012, 23:153-162.
    • (2012) J Nutr Biochem , vol.23 , pp. 153-162
    • Poudyal, H.1    Panchal, S.K.2    Waanders, J.3    Ward, L.4    Brown, L.5
  • 193
    • 79955695959 scopus 로고    scopus 로고
    • Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design
    • Rhee Y., Brunt A. Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design. Nutr J 2011, 10:44.
    • (2011) Nutr J , vol.10 , pp. 44
    • Rhee, Y.1    Brunt, A.2
  • 195
    • 0036845378 scopus 로고    scopus 로고
    • The impact of dietary fat composition on serum leptin concentrations in healthy nonobese men and women
    • Kratz M., von Eckardstein A., Fobker M., Buyken A., Posny N., Schulte H., et al. The impact of dietary fat composition on serum leptin concentrations in healthy nonobese men and women. J Clin Endocrinol Metab 2002, 87:5008-5014.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5008-5014
    • Kratz, M.1    von Eckardstein, A.2    Fobker, M.3    Buyken, A.4    Posny, N.5    Schulte, H.6
  • 196
    • 34547687656 scopus 로고    scopus 로고
    • Adiponectin levels are reduced, independent of polymorphisms in the adiponectin gene, after supplementation with α-linolenic acid among healthy adults
    • Nelson T.L., Stevens J.R., Hickey M.S. Adiponectin levels are reduced, independent of polymorphisms in the adiponectin gene, after supplementation with α-linolenic acid among healthy adults. Metabolism 2007, 56:1209-1215.
    • (2007) Metabolism , vol.56 , pp. 1209-1215
    • Nelson, T.L.1    Stevens, J.R.2    Hickey, M.S.3
  • 197
    • 84888043856 scopus 로고    scopus 로고
    • An acute intake of a walnut-enriched meal improves postprandial adiponectin response in healthy young adults
    • Lozano A., Perez-Martinez P., Marin C., Tinahones F.J., Delgado-Lista J., Cruz-Teno C., et al. An acute intake of a walnut-enriched meal improves postprandial adiponectin response in healthy young adults. Nutr Res 2013, 33:1012-1018.
    • (2013) Nutr Res , vol.33 , pp. 1012-1018
    • Lozano, A.1    Perez-Martinez, P.2    Marin, C.3    Tinahones, F.J.4    Delgado-Lista, J.5    Cruz-Teno, C.6
  • 198
    • 67649515581 scopus 로고    scopus 로고
    • The metabolic syndrome of ω3-depleted rats. II. Body weight, adipose tissue mass and glycemic homeostasis
    • Sener A., Zhang Y., Bulur N., Louchami K., Malaisse W.J., Carpentier Y.A. The metabolic syndrome of ω3-depleted rats. II. Body weight, adipose tissue mass and glycemic homeostasis. Int J Mol Med 2009, 24:125-129.
    • (2009) Int J Mol Med , vol.24 , pp. 125-129
    • Sener, A.1    Zhang, Y.2    Bulur, N.3    Louchami, K.4    Malaisse, W.J.5    Carpentier, Y.A.6
  • 199
    • 63849205389 scopus 로고    scopus 로고
    • Alpha-linolenic acid-rich flaxseed oil ingestion increases plasma adiponectin level in rats
    • Sekine S., Sasanuki S., Murano Y., Aoyama T., Takeuchi H. Alpha-linolenic acid-rich flaxseed oil ingestion increases plasma adiponectin level in rats. Int J Vitam Nutr Res 2008, 78:223-229.
    • (2008) Int J Vitam Nutr Res , vol.78 , pp. 223-229
    • Sekine, S.1    Sasanuki, S.2    Murano, Y.3    Aoyama, T.4    Takeuchi, H.5
  • 200
    • 84876799918 scopus 로고    scopus 로고
    • Leptin, resistin and visfatin: the missing link between endocrine metabolic disorders and immunity
    • Al-Suhaimi E.A., Shehzad A. Leptin, resistin and visfatin: the missing link between endocrine metabolic disorders and immunity. Eur J Med Res 2013, 18:12.
    • (2013) Eur J Med Res , vol.18 , pp. 12
    • Al-Suhaimi, E.A.1    Shehzad, A.2
  • 201
    • 83555174339 scopus 로고    scopus 로고
    • The alpha linolenic acid content of flaxseed is associated with an induction of adipose leptin expression
    • McCullough R.S., Edel A.L., Bassett C.M., Lavallee R.K., Dibrov E., Blackwood D.P., et al. The alpha linolenic acid content of flaxseed is associated with an induction of adipose leptin expression. Lipids 2011, 46:1043-1052.
    • (2011) Lipids , vol.46 , pp. 1043-1052
    • McCullough, R.S.1    Edel, A.L.2    Bassett, C.M.3    Lavallee, R.K.4    Dibrov, E.5    Blackwood, D.P.6
  • 202
    • 84891034184 scopus 로고    scopus 로고
    • Alpha-Linolenic acid suppresses cholesterol and triacylglycerol biosynthesis pathway by suppressing SREBP-2, SREBP-1a and -1c expression
    • Fukumitsu S., Villareal M.O., Onaga S., Aida K., Han J., Isoda H. alpha-Linolenic acid suppresses cholesterol and triacylglycerol biosynthesis pathway by suppressing SREBP-2, SREBP-1a and -1c expression. Cytotechnology 2013, 65:899-907.
    • (2013) Cytotechnology , vol.65 , pp. 899-907
    • Fukumitsu, S.1    Villareal, M.O.2    Onaga, S.3    Aida, K.4    Han, J.5    Isoda, H.6
  • 203
    • 79956160797 scopus 로고    scopus 로고
    • Opposing effects of omega-3 and omega-6 long chain polyunsaturated fatty acids on the expression of lipogenic genes in omental and retroperitoneal adipose depots in the rat
    • Muhlhausler B.S., Cook-Johnson R., James M., Miljkovic D., Duthoit E., Gibson R. Opposing effects of omega-3 and omega-6 long chain polyunsaturated fatty acids on the expression of lipogenic genes in omental and retroperitoneal adipose depots in the rat. J Nutr Metab 2010, 2010:927836.
    • (2010) J Nutr Metab , vol.2010 , pp. 927836
    • Muhlhausler, B.S.1    Cook-Johnson, R.2    James, M.3    Miljkovic, D.4    Duthoit, E.5    Gibson, R.6
  • 204
    • 53249103670 scopus 로고    scopus 로고
    • Id3, E47, and SREBP-1c: fat factors controlling adiponectin expression
    • Rahmouni K., Sigmund C.D. Id3, E47, and SREBP-1c: fat factors controlling adiponectin expression. Circ Res 2008, 103:565-567.
    • (2008) Circ Res , vol.103 , pp. 565-567
    • Rahmouni, K.1    Sigmund, C.D.2
  • 205
    • 0031770679 scopus 로고    scopus 로고
    • Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor
    • Mason M.M., He Y., Chen H., Quon M.J., Reitman M. Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor. Endocrinology 1998, 139:1013-1022.
    • (1998) Endocrinology , vol.139 , pp. 1013-1022
    • Mason, M.M.1    He, Y.2    Chen, H.3    Quon, M.J.4    Reitman, M.5
  • 206
    • 84886948316 scopus 로고    scopus 로고
    • Dietary Salba (Salvia hispanica L) seed rich in α-linolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats
    • Oliva M.E., Ferreira M.R., Chicco A., Lombardo Y.B. Dietary Salba (Salvia hispanica L) seed rich in α-linolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats. Prostaglandins Leukot Essent Fatty Acids 2013, 89:279-289.
    • (2013) Prostaglandins Leukot Essent Fatty Acids , vol.89 , pp. 279-289
    • Oliva, M.E.1    Ferreira, M.R.2    Chicco, A.3    Lombardo, Y.B.4
  • 207
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001, 7:941-946.
    • (2001) Nat Med , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Terauchi, Y.4    Kubota, N.5    Hara, K.6
  • 208
    • 0842324682 scopus 로고    scopus 로고
    • Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes
    • Fasshauer M., Klein J., Kralisch S., Klier M., Lossner U., Bluher M., et al. Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes. FEBS Lett 2004, 558:27-32.
    • (2004) FEBS Lett , vol.558 , pp. 27-32
    • Fasshauer, M.1    Klein, J.2    Kralisch, S.3    Klier, M.4    Lossner, U.5    Bluher, M.6
  • 209
    • 33750578279 scopus 로고    scopus 로고
    • Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor α
    • Yoon M.J., Lee G.Y., Chung J.J., Ahn Y.H., Hong S.H., Kim J.B. Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor α. Diabetes 2006, 55:2562-2570.
    • (2006) Diabetes , vol.55 , pp. 2562-2570
    • Yoon, M.J.1    Lee, G.Y.2    Chung, J.J.3    Ahn, Y.H.4    Hong, S.H.5    Kim, J.B.6
  • 210
    • 7944228499 scopus 로고    scopus 로고
    • Dietary α-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women
    • Zhao G., Etherton T.D., Martin K.R., West S.G., Gillies P.J., Kris-Etherton P.M. Dietary α-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women. J Nutr 2004, 134:2991-2997.
    • (2004) J Nutr , vol.134 , pp. 2991-2997
    • Zhao, G.1    Etherton, T.D.2    Martin, K.R.3    West, S.G.4    Gillies, P.J.5    Kris-Etherton, P.M.6
  • 211
    • 71049173637 scopus 로고    scopus 로고
    • Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome
    • Satoh N., Shimatsu A., Kotani K., Himeno A., Majima T., Yamada K., et al. Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome. Hypertens Res 2009, 32:1004-1008.
    • (2009) Hypertens Res , vol.32 , pp. 1004-1008
    • Satoh, N.1    Shimatsu, A.2    Kotani, K.3    Himeno, A.4    Majima, T.5    Yamada, K.6
  • 212
    • 34548274430 scopus 로고    scopus 로고
    • Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects
    • Itoh M., Suganami T., Satoh N., Tanimoto-Koyama K., Yuan X., Tanaka M., et al. Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler Thromb Vasc Biol 2007, 27:1918-1925.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1918-1925
    • Itoh, M.1    Suganami, T.2    Satoh, N.3    Tanimoto-Koyama, K.4    Yuan, X.5    Tanaka, M.6
  • 214
    • 78149275191 scopus 로고    scopus 로고
    • Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation
    • Kalupahana N.S., Claycombe K., Newman S.J., Stewart T., Siriwardhana N., Matthan N., et al. Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation. J Nutr 2010, 140:1915-1922.
    • (2010) J Nutr , vol.140 , pp. 1915-1922
    • Kalupahana, N.S.1    Claycombe, K.2    Newman, S.J.3    Stewart, T.4    Siriwardhana, N.5    Matthan, N.6
  • 215
    • 79551501873 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid (EPA) treatment on insulin sensitivity in an animal model of diabetes: improvement of the inflammatory status
    • Figueras M., Olivan M., Busquets S., Lopez-Soriano F.J., Argiles J.M. Effects of eicosapentaenoic acid (EPA) treatment on insulin sensitivity in an animal model of diabetes: improvement of the inflammatory status. Obesity (Silver Spring) 2011, 19:362-369.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 362-369
    • Figueras, M.1    Olivan, M.2    Busquets, S.3    Lopez-Soriano, F.J.4    Argiles, J.M.5
  • 216
    • 77957606885 scopus 로고    scopus 로고
    • Antiobesity effect of eicosapentaenoic acid in high-fat/high-sucrose diet-induced obesity: importance of hepatic lipogenesis
    • Sato A., Kawano H., Notsu T., Ohta M., Nakakuki M., Mizuguchi K., et al. Antiobesity effect of eicosapentaenoic acid in high-fat/high-sucrose diet-induced obesity: importance of hepatic lipogenesis. Diabetes 2010, 59:2495-2504.
    • (2010) Diabetes , vol.59 , pp. 2495-2504
    • Sato, A.1    Kawano, H.2    Notsu, T.3    Ohta, M.4    Nakakuki, M.5    Mizuguchi, K.6
  • 218
    • 0034682474 scopus 로고    scopus 로고
    • Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets
    • Kakuma T., Lee Y., Higa M., Wang Z., Pan W., Shimomura I., et al. Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets. Proc Natl Acad Sci U S A 2000, 97:8536-8541.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8536-8541
    • Kakuma, T.1    Lee, Y.2    Higa, M.3    Wang, Z.4    Pan, W.5    Shimomura, I.6
  • 219
    • 33644821916 scopus 로고    scopus 로고
    • Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans
    • Hulver M.W., Berggren J.R., Carper M.J., Miyazaki M., Ntambi J.M., Hoffman E.P., et al. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab 2005, 2:251-261.
    • (2005) Cell Metab , vol.2 , pp. 251-261
    • Hulver, M.W.1    Berggren, J.R.2    Carper, M.J.3    Miyazaki, M.4    Ntambi, J.M.5    Hoffman, E.P.6
  • 220
    • 43249083481 scopus 로고    scopus 로고
    • Free fatty acids and skeletal muscle insulin resistance
    • Kraegen E.W., Cooney G.J. Free fatty acids and skeletal muscle insulin resistance. Curr Opin Lipidol 2008, 19:235-241.
    • (2008) Curr Opin Lipidol , vol.19 , pp. 235-241
    • Kraegen, E.W.1    Cooney, G.J.2
  • 221
    • 33747034520 scopus 로고    scopus 로고
    • Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c
    • Biddinger S.B., Miyazaki M., Boucher J., Ntambi J.M., Kahn C.R. Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c. Diabetes 2006, 55:2032-2041.
    • (2006) Diabetes , vol.55 , pp. 2032-2041
    • Biddinger, S.B.1    Miyazaki, M.2    Boucher, J.3    Ntambi, J.M.4    Kahn, C.R.5
  • 222
    • 61449105003 scopus 로고    scopus 로고
    • Down-regulation in muscle and liver lipogenic genes: EPA ethyl ester treatment in lean and overweight (high-fat-fed) rats
    • Perez-Echarri N., Perez-Matute P., Marcos-Gomez B., Marti A., Martinez J.A., Moreno-Aliaga M.J. Down-regulation in muscle and liver lipogenic genes: EPA ethyl ester treatment in lean and overweight (high-fat-fed) rats. J Nutr Biochem 2009, 20:705-714.
    • (2009) J Nutr Biochem , vol.20 , pp. 705-714
    • Perez-Echarri, N.1    Perez-Matute, P.2    Marcos-Gomez, B.3    Marti, A.4    Martinez, J.A.5    Moreno-Aliaga, M.J.6
  • 223
  • 224
    • 79551499779 scopus 로고    scopus 로고
    • Eicosapentaenoic acid and rosiglitazone increase adiponectin in an additive and PPARγ-dependent manner in human adipocytes
    • Tishinsky J.M., Ma D.W., Robinson L.E. Eicosapentaenoic acid and rosiglitazone increase adiponectin in an additive and PPARγ-dependent manner in human adipocytes. Obesity (Silver Spring) 2011, 19:262-268.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 262-268
    • Tishinsky, J.M.1    Ma, D.W.2    Robinson, L.E.3
  • 225
    • 0033820422 scopus 로고    scopus 로고
    • 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes
    • Salt I.P., Connell J.M., Gould G.W. 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. Diabetes 2000, 49:1649-1656.
    • (2000) Diabetes , vol.49 , pp. 1649-1656
    • Salt, I.P.1    Connell, J.M.2    Gould, G.W.3
  • 227
    • 67449097764 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid ethyl ester on visfatin and apelin in lean and overweight (cafeteria diet-fed) rats
    • Perez-Echarri N., Perez-Matute P., Marcos-Gomez B., Martinez J.A., Moreno-Aliaga M.J. Effects of eicosapentaenoic acid ethyl ester on visfatin and apelin in lean and overweight (cafeteria diet-fed) rats. Br J Nutr 2009, 101:1059-1067.
    • (2009) Br J Nutr , vol.101 , pp. 1059-1067
    • Perez-Echarri, N.1    Perez-Matute, P.2    Marcos-Gomez, B.3    Martinez, J.A.4    Moreno-Aliaga, M.J.5
  • 228
    • 33846527541 scopus 로고    scopus 로고
    • Visfatin, an adipocytokine with proinflammatory and immunomodulating properties
    • Moschen A.R., Kaser A., Enrich B., Mosheimer B., Theurl M., Niederegger H., et al. Visfatin, an adipocytokine with proinflammatory and immunomodulating properties. J Immunol 2007, 178:1748-1758.
    • (2007) J Immunol , vol.178 , pp. 1748-1758
    • Moschen, A.R.1    Kaser, A.2    Enrich, B.3    Mosheimer, B.4    Theurl, M.5    Niederegger, H.6
  • 229
    • 0030700020 scopus 로고    scopus 로고
    • Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues
    • Raclot T., Groscolas R., Langin D., Ferre P. Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues. J Lipid Res 1997, 38:1963-1972.
    • (1997) J Lipid Res , vol.38 , pp. 1963-1972
    • Raclot, T.1    Groscolas, R.2    Langin, D.3    Ferre, P.4
  • 230
    • 27744482030 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce β-oxidation in white fat
    • Flachs P., Horakova O., Brauner P., Rossmeisl M., Pecina P., Franssen-van Hal N., et al. Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce β-oxidation in white fat. Diabetologia 2005, 48:2365-2375.
    • (2005) Diabetologia , vol.48 , pp. 2365-2375
    • Flachs, P.1    Horakova, O.2    Brauner, P.3    Rossmeisl, M.4    Pecina, P.5    Franssen-van Hal, N.6
  • 231
    • 0034789874 scopus 로고    scopus 로고
    • Chronic docosahexaenoic acid intake enhances expression of the gene for uncoupling protein 3 and affects pleiotropic mRNA levels in skeletal muscle of aged C57BL/6NJcl mice
    • Cha S.H., Fukushima A., Sakuma K., Kagawa Y. Chronic docosahexaenoic acid intake enhances expression of the gene for uncoupling protein 3 and affects pleiotropic mRNA levels in skeletal muscle of aged C57BL/6NJcl mice. J Nutr 2001, 131:2636-2642.
    • (2001) J Nutr , vol.131 , pp. 2636-2642
    • Cha, S.H.1    Fukushima, A.2    Sakuma, K.3    Kagawa, Y.4
  • 232
    • 84891153713 scopus 로고    scopus 로고
    • Differential effects of eicosapentaenoic acid and docosahexaenoic acid in promoting the differentiation of 3T3-L1 preadipocytes
    • Murali G., Desouza C.V., Clevenger M.E., Ramalingam R., Saraswathi V. Differential effects of eicosapentaenoic acid and docosahexaenoic acid in promoting the differentiation of 3T3-L1 preadipocytes. Prostaglandins Leukot Essent Fatty Acids 2014, 90:13-21.
    • (2014) Prostaglandins Leukot Essent Fatty Acids , vol.90 , pp. 13-21
    • Murali, G.1    Desouza, C.V.2    Clevenger, M.E.3    Ramalingam, R.4    Saraswathi, V.5


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