-
1
-
-
0028229508
-
Insulin resistance or insulin deficiency. Which is the primary cause of NIDDM?
-
Taylor SI, Accili D, Imai Y (1994) Insulin resistance or insulin deficiency. Which is the primary cause of NIDDM? Diabetes 43:735-740
-
(1994)
Diabetes
, vol.43
, pp. 735-740
-
-
Taylor, S.I.1
Accili, D.2
Imai, Y.3
-
2
-
-
0026572747
-
Pathogenesis of type 2 (non-insulin dependent) diabetes mellitus: A balanced overview
-
DeFronzo RA (1992) Pathogenesis of type 2 (non-insulin dependent) diabetes mellitus: a balanced overview. Diabetologia 35:389-397
-
(1992)
Diabetologia
, vol.35
, pp. 389-397
-
-
DeFronzo, R.A.1
-
3
-
-
0026110135
-
Banting lecture 1990. Beta-cells in type II diabetes mellitus
-
Porte D Jr (1991) Banting lecture 1990. Beta-cells in type II diabetes mellitus. Diabetes 40:166-180
-
(1991)
Diabetes
, vol.40
, pp. 166-180
-
-
Porte Jr., D.1
-
4
-
-
0028997729
-
Lilly Lecture 1994. The beta-cell in diabetes: From molecular genetics to clinical research
-
Polonsky KS (1995) Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research. Diabetes 44:705-717
-
(1995)
Diabetes
, vol.44
, pp. 705-717
-
-
Polonsky, K.S.1
-
5
-
-
0029888870
-
Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat
-
Stein DT, Esser V, Stevenson BE et al (1996) Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. J Clin Invest 97:2728-2735
-
(1996)
J Clin Invest
, vol.97
, pp. 2728-2735
-
-
Stein, D.T.1
Esser, V.2
Stevenson, B.E.3
-
6
-
-
0034090489
-
Fatty acids and insulin secretion
-
Grill V, Qvigstad E (2000) Fatty acids and insulin secretion. Br J Nutr 83 (Suppl 1):S79-S84
-
(2000)
Br J Nutr
, vol.83
, Issue.1 SUPPL.
-
-
Grill, V.1
Qvigstad, E.2
-
7
-
-
0036217052
-
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
-
Lewis GF, Carpentier A, Adeli K, Giacca A (2002) Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 23:201-229
-
(2002)
Endocr Rev
, vol.23
, pp. 201-229
-
-
Lewis, G.F.1
Carpentier, A.2
Adeli, K.3
Giacca, A.4
-
8
-
-
0141755328
-
A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes
-
Kashyap S, Belfort R, Gastaldelli A et al (2003) A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes. Diabetes 52:2461-2474
-
(2003)
Diabetes
, vol.52
, pp. 2461-2474
-
-
Kashyap, S.1
Belfort, R.2
Gastaldelli, A.3
-
9
-
-
0036896505
-
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: Role in beta-cell adaptation and failure in the etiology of diabetes
-
Prentki M, Joly E, El Assaad W, Roduit R (2002) Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. Diabetes 51 (Suppl 3):S405-S413
-
(2002)
Diabetes
, vol.51
, Issue.3 SUPPL.
-
-
Prentki, M.1
Joly, E.2
El Assaad, W.3
Roduit, R.4
-
10
-
-
0030876806
-
The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation
-
Stein DT, Stevenson BE, Chester MW et al (1997) The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation. J Clin Invest 100:398-403
-
(1997)
J Clin Invest
, vol.100
, pp. 398-403
-
-
Stein, D.T.1
Stevenson, B.E.2
Chester, M.W.3
-
11
-
-
0036434385
-
Interaction between specific fatty acids, GLP-1 and insulin secretion in humans
-
Beysen C, Karpe F, Fielding BA, Clark A, Levy JC, Frayn KN (2002) Interaction between specific fatty acids, GLP-1 and insulin secretion in humans. Diabetologia 45:1533-1541
-
(2002)
Diabetologia
, vol.45
, pp. 1533-1541
-
-
Beysen, C.1
Karpe, F.2
Fielding, B.A.3
Clark, A.4
Levy, J.C.5
Frayn, K.N.6
-
12
-
-
0347990354
-
Direct and indirect mechanisms regulating secretion of glucagon-like peptide-1 and glucagon-like peptide-2
-
Brubaker PL, Anini Y (2003) Direct and indirect mechanisms regulating secretion of glucagon-like peptide-1 and glucagon-like peptide-2. Can J Physiol Pharmacol 81:1005-1012
-
(2003)
Can J Physiol Pharmacol
, vol.81
, pp. 1005-1012
-
-
Brubaker, P.L.1
Anini, Y.2
-
13
-
-
0034005968
-
Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes
-
Carpentier A, Mittelman SD, Bergman RN, Giacca A, Lewis GF (2000) Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes 49:399-408
-
(2000)
Diabetes
, vol.49
, pp. 399-408
-
-
Carpentier, A.1
Mittelman, S.D.2
Bergman, R.N.3
Giacca, A.4
Lewis, G.F.5
-
14
-
-
1042302780
-
Diagnosis and classification of diabetes mellitus
-
American Diabetes Association (2004) Diagnosis and classification of diabetes mellitus. Diabetes Care 27:S5-S10
-
(2004)
Diabetes Care
, vol.27
-
-
-
15
-
-
0032999260
-
Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation
-
Carpentier A, Mittelman SD, Lamarche B, Bergman RN, Giacca A, Lewis GF (1999) Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. Am J Physiol 276:E1055-E1066
-
(1999)
Am J Physiol
, vol.276
-
-
Carpentier, A.1
Mittelman, S.D.2
Lamarche, B.3
Bergman, R.N.4
Giacca, A.5
Lewis, G.F.6
-
16
-
-
0028284103
-
Interactions of lipoprotein lipase with the active-site inhibitor tetrahydrolipstatin (Orlistat)
-
Lookene A, Skottova N, Olivecrona G (1994) Interactions of lipoprotein lipase with the active-site inhibitor tetrahydrolipstatin (Orlistat). Eur J Biochem 222:395-403
-
(1994)
Eur J Biochem
, vol.222
, pp. 395-403
-
-
Lookene, A.1
Skottova, N.2
Olivecrona, G.3
-
17
-
-
0018520840
-
Glucose clamp technique: A method for quantifying insulin secretion and resistance
-
DeFronzo RA, Tobin JD, Andres R (1979) Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223
-
(1979)
Am J Physiol
, vol.237
-
-
DeFronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
18
-
-
0026504160
-
Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance
-
Van Cauter E, Mestrez F, Sturis J, Polonsky KS (1992) Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 41:368-377
-
(1992)
Diabetes
, vol.41
, pp. 368-377
-
-
Van Cauter, E.1
Mestrez, F.2
Sturis, J.3
Polonsky, K.S.4
-
19
-
-
0036330904
-
Plasma total and free fatty acids composition in human non-alcoholic steatohepatitis
-
de Almeida IT, Cortez-Pinto H, Fidalgo G, Rodrigues D, Camilo ME (2002) Plasma total and free fatty acids composition in human non-alcoholic steatohepatitis. Clin Nutr 21:219-223
-
(2002)
Clin Nutr
, vol.21
, pp. 219-223
-
-
De Almeida, I.T.1
Cortez-Pinto, H.2
Fidalgo, G.3
Rodrigues, D.4
Camilo, M.E.5
-
20
-
-
0029046673
-
Effects of a 48-h fat infusion on insulin secretion and glucose utilization
-
Boden G, Chen X, Rosner J, Barton M (1995) Effects of a 48-h fat infusion on insulin secretion and glucose utilization. Diabetes 44:1239-1242
-
(1995)
Diabetes
, vol.44
, pp. 1239-1242
-
-
Boden, G.1
Chen, X.2
Rosner, J.3
Barton, M.4
-
21
-
-
0035195976
-
Effect of increased plasma non-esterified fatty acids (NEFA) on arginine-stimulated insulin secretion in obese humans
-
Carpentier A, Giacca A, Lewis GF (2001) Effect of increased plasma non-esterified fatty acids (NEFA) on arginine-stimulated insulin secretion in obese humans. Diabetologia 44:1989-1997
-
(2001)
Diabetologia
, vol.44
, pp. 1989-1997
-
-
Carpentier, A.1
Giacca, A.2
Lewis, G.F.3
-
22
-
-
0038321316
-
Free fatty acid-mediated impairment of glucose-stimulated insulin secretion in nondiabetic Oji-Cree individuals from the Sandy Lake community of Ontario, Canada: A population at very high risk for developing type 2 diabetes
-
Carpentier A, Zinman B, Leung N et al (2003) Free fatty acid-mediated impairment of glucose-stimulated insulin secretion in nondiabetic Oji-Cree individuals from the Sandy Lake community of Ontario, Canada: a population at very high risk for developing type 2 diabetes. Diabetes 52:1485-1495
-
(2003)
Diabetes
, vol.52
, pp. 1485-1495
-
-
Carpentier, A.1
Zinman, B.2
Leung, N.3
-
23
-
-
1542285102
-
Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men
-
Leung N, Sakaue T, Carpentier A, Uffelman K, Giacca A, Lewis GF (2004) Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men. Diabetologia 47:204-213
-
(2004)
Diabetologia
, vol.47
, pp. 204-213
-
-
Leung, N.1
Sakaue, T.2
Carpentier, A.3
Uffelman, K.4
Giacca, A.5
Lewis, G.F.6
-
24
-
-
19944392882
-
Comparison of predictive equations for resting metabolic rate in healthy nonobese and obese adults: A systematic review
-
Frankenfield D, Roth-Yousey L, Compher C (2005) Comparison of predictive equations for resting metabolic rate in healthy nonobese and obese adults: a systematic review. J Am Diet Assoc 105:775-789
-
(2005)
J Am Diet Assoc
, vol.105
, pp. 775-789
-
-
Frankenfield, D.1
Roth-Yousey, L.2
Compher, C.3
-
25
-
-
0036260039
-
Sensitivity to acute insulin-mediated suppression of plasma free fatty acids is not a determinant of fasting VLDL triglyceride secretion in healthy humans
-
Carpentier A, Patterson BW, Leung N, Lewis GF (2002) Sensitivity to acute insulin-mediated suppression of plasma free fatty acids is not a determinant of fasting VLDL triglyceride secretion in healthy humans. Diabetes 51:1867-1875
-
(2002)
Diabetes
, vol.51
, pp. 1867-1875
-
-
Carpentier, A.1
Patterson, B.W.2
Leung, N.3
Lewis, G.F.4
-
26
-
-
27144472377
-
On the suppression of plasma nonesterified fatty acids by insulin during enhanced intravascular lipolysis in humans
-
Carpentier AC, Frisch F, Cyr D et al (2005) On the suppression of plasma nonesterified fatty acids by insulin during enhanced intravascular lipolysis in humans. Am J Physiol Endocrinol Metab 289:E849-E856
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
-
-
Carpentier, A.C.1
Frisch, F.2
Cyr, D.3
-
27
-
-
0033587626
-
Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion
-
Warnotte C, Nenquin M, Henquin JC (1999) Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. Mol Cell Endocrinol 153:147-153
-
(1999)
Mol Cell Endocrinol
, vol.153
, pp. 147-153
-
-
Warnotte, C.1
Nenquin, M.2
Henquin, J.C.3
-
28
-
-
0028268936
-
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
-
Zhou YP, Grill VE (1994) Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93:870-876
-
(1994)
J Clin Invest
, vol.93
, pp. 870-876
-
-
Zhou, Y.P.1
Grill, V.E.2
-
29
-
-
0031054064
-
Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1
-
Brun T, Assimacopoulos-Jeannet F, Corkey BE, Prentki M (1997) Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1. Diabetes 46:393-400
-
(1997)
Diabetes
, vol.46
, pp. 393-400
-
-
Brun, T.1
Assimacopoulos-Jeannet, F.2
Corkey, B.E.3
Prentki, M.4
-
30
-
-
0033042342
-
Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats
-
Mason TM, Goh T, Tchipashvili V et al (1999) Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats. Diabetes 48:524-530
-
(1999)
Diabetes
, vol.48
, pp. 524-530
-
-
Mason, T.M.1
Goh, T.2
Tchipashvili, V.3
-
31
-
-
0036260126
-
The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats
-
Dobbins RL, Szczepaniak LS, Myhill J et al (2002) The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats. Diabetes 51:1825-1833
-
(2002)
Diabetes
, vol.51
, pp. 1825-1833
-
-
Dobbins, R.L.1
Szczepaniak, L.S.2
Myhill, J.3
-
32
-
-
0035123646
-
Evidence for gene-nutrient interaction at the PPARgamma locus
-
Luan J, Browne PO, Harding AH et al (2001) Evidence for gene-nutrient interaction at the PPARgamma locus. Diabetes 50:686-689
-
(2001)
Diabetes
, vol.50
, pp. 686-689
-
-
Luan, J.1
Browne, P.O.2
Harding, A.H.3
-
33
-
-
0033524415
-
Ligand selectivity of the peroxisome proliferator-activated receptor alpha
-
Lin Q, Ruuska SE, Shaw NS, Dong D, Noy N (1999) Ligand selectivity of the peroxisome proliferator-activated receptor alpha. Biochemistry 38:185-190
-
(1999)
Biochemistry
, vol.38
, pp. 185-190
-
-
Lin, Q.1
Ruuska, S.E.2
Shaw, N.S.3
Dong, D.4
Noy, N.5
-
34
-
-
0033587626
-
Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion
-
Warnotte C, Nenquin M, Henquin JC (1999) Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. Mol Cell Endocrinol 153:147-153
-
(1999)
Mol Cell Endocrinol
, vol.153
, pp. 147-153
-
-
Warnotte, C.1
Nenquin, M.2
Henquin, J.C.3
-
35
-
-
0032991716
-
Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets
-
Chan CB, MacDonald PE, Saleh MC, Johns DC, Marban E, Wheeler MB (1999) Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets. Diabetes 48:1482-1486
-
(1999)
Diabetes
, vol.48
, pp. 1482-1486
-
-
Chan, C.B.1
MacDonald, P.E.2
Saleh, M.C.3
Johns, D.C.4
Marban, E.5
Wheeler, M.B.6
-
36
-
-
0031686714
-
Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals
-
Pamplona R, Portero-Otin M, Riba D et al (1998) Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals. J Lipid Res 39:1989-1994
-
(1998)
J Lipid Res
, vol.39
, pp. 1989-1994
-
-
Pamplona, R.1
Portero-Otin, M.2
Riba, D.3
-
37
-
-
0036796875
-
Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
-
Evans JL, Goldfme ID, Maddux BA, Grodsky GM (2002) Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 23:599-622
-
(2002)
Endocr Rev
, vol.23
, pp. 599-622
-
-
Evans, J.L.1
Goldfme, I.D.2
Maddux, B.A.3
Grodsky, G.M.4
-
38
-
-
0027395358
-
The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids
-
Borkman M, Storlien LH, Pan DA, Jenkins AB, Chisholm DJ, Campbell LV (1993) The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. N Engl J Med 328:238-244
-
(1993)
N Engl J Med
, vol.328
, pp. 238-244
-
-
Borkman, M.1
Storlien, L.H.2
Pan, D.A.3
Jenkins, A.B.4
Chisholm, D.J.5
Campbell, L.V.6
-
39
-
-
0026087478
-
Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid
-
Storlien LH, Jenkins AB, Chisholm DJ, Pascoe WS, Khouri S, Kraegen EW (1991) Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid. Diabetes 40:280-289
-
(1991)
Diabetes
, vol.40
, pp. 280-289
-
-
Storlien, L.H.1
Jenkins, A.B.2
Chisholm, D.J.3
Pascoe, W.S.4
Khouri, S.5
Kraegen, E.W.6
-
40
-
-
0035081372
-
Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study
-
Vessby B, Unsitupa M, Hermansen K et al (2001) Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: the KANWU Study. Diabetologia 44:312-319
-
(2001)
Diabetologia
, vol.44
, pp. 312-319
-
-
Vessby, B.1
Unsitupa, M.2
Hermansen, K.3
-
41
-
-
0019810028
-
Physiologic evaluation of factors controlling glucose tolerance in man: Measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose
-
Bergman RN, Phillips LS, Cobelli C (1981) Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 68:1456-1467
-
(1981)
J Clin Invest
, vol.68
, pp. 1456-1467
-
-
Bergman, R.N.1
Phillips, L.S.2
Cobelli, C.3
-
42
-
-
0141446228
-
Enhancing incretin action for the treatment of type 2 diabetes
-
Drucker DJ (2003) Enhancing incretin action for the treatment of type 2 diabetes. Diabetes Care 26:2929-2940
-
(2003)
Diabetes Care
, vol.26
, pp. 2929-2940
-
-
Drucker, D.J.1
-
43
-
-
0035095031
-
Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1
-
Rocca AS, LaGreca J, Kalitsky J, Brubaker PL (2001) Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1. Endocrinology 142:1148-1155
-
(2001)
Endocrinology
, vol.142
, pp. 1148-1155
-
-
Rocca, A.S.1
LaGreca, J.2
Kalitsky, J.3
Brubaker, P.L.4
-
44
-
-
0033028489
-
Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans
-
Xiao Q, Boushey RP, Drucker DJ, Brubaker PL (1999) Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans. Gastroenterology 117:99-105
-
(1999)
Gastroenterology
, vol.117
, pp. 99-105
-
-
Xiao, Q.1
Boushey, R.P.2
Drucker, D.J.3
Brubaker, P.L.4
-
45
-
-
0032999369
-
Free fatty acids impair hepatic insulin extraction in vivo
-
Wiesenthal SR, Sandhu H, McCall RH et al (1999) Free fatty acids impair hepatic insulin extraction in vivo. Diabetes 48:766-774
-
(1999)
Diabetes
, vol.48
, pp. 766-774
-
-
Wiesenthal, S.R.1
Sandhu, H.2
McCall, R.H.3
-
46
-
-
0036772294
-
Pathogenesis and prediction of diabetes mellitus: Lessons from integrative physiology
-
Bergman RN (2002) Pathogenesis and prediction of diabetes mellitus: lessons from integrative physiology. Mt Sinai J Med 69:280-290
-
(2002)
Mt Sinai J Med
, vol.69
, pp. 280-290
-
-
Bergman, R.N.1
-
47
-
-
0028849148
-
Opposite effects of short- And long-term fatty acid infusion on insulin secretion in healthy subjects
-
Paolisso G, Gambardella A, Amato L et al (1995) Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects. Diabetologia 38:1295-1299
-
(1995)
Diabetologia
, vol.38
, pp. 1295-1299
-
-
Paolisso, G.1
Gambardella, A.2
Amato, L.3
|