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Volumn 139, Issue 3, 1998, Pages 1013-1022

Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; TRANSCRIPTION FACTOR SP1;

EID: 0031770679     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.3.5792     Document Type: Article
Times cited : (130)

References (61)
  • 2
    • 0030902584 scopus 로고    scopus 로고
    • Leptin expression and action: New experimental paradigms
    • Flier JS 1997 Leptin expression and action: new experimental paradigms. Proc Natl Acad Sci USA 94:4242-4245
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4242-4245
    • Flier, J.S.1
  • 5
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • Coleman DL 1978 Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14:141-148
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 7
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P 1995 Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 9
    • 0029021599 scopus 로고
    • Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake
    • De Vos P, Saladin R, Auwerx J, Staels B 1995 Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem 270:15958-15961
    • (1995) J Biol Chem , vol.270 , pp. 15958-15961
    • De Vos, P.1    Saladin, R.2    Auwerx, J.3    Staels, B.4
  • 12
    • 0028849084 scopus 로고
    • The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein α
    • He Y, Chen H, Quon MJ, Reitman M 1995 The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein α. J Biol Chem 270:28887-28891
    • (1995) J Biol Chem , vol.270 , pp. 28887-28891
    • He, Y.1    Chen, H.2    Quon, M.J.3    Reitman, M.4
  • 14
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR 1989 Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 15
  • 17
    • 0030058221 scopus 로고    scopus 로고
    • Design of a C/EBP-specific, dominant-negative bZIP protein with both inhibitory and gain-of-function properties
    • Olive M, Williams SC, Dezan C, Johnson PF, Vinson C 1996 Design of a C/EBP-specific, dominant-negative bZIP protein with both inhibitory and gain-of-function properties. J Biol Chem 271:2040-2047
    • (1996) J Biol Chem , vol.271 , pp. 2040-2047
    • Olive, M.1    Williams, S.C.2    Dezan, C.3    Johnson, P.F.4    Vinson, C.5
  • 18
    • 0026052619 scopus 로고
    • A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro
    • Williams SC, Cantwell CA, Johnson PF 1991 A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. Genes Dev 5:1553-1567
    • (1991) Genes Dev , vol.5 , pp. 1553-1567
    • Williams, S.C.1    Cantwell, C.A.2    Johnson, P.F.3
  • 19
    • 0027284458 scopus 로고
    • Transfection of DNA into isolated rat adipose cells by electroporation: Evaluation of promoter activity in transfected adipose cells which are highly responsive to insulin after one day in culture
    • Quon MJ, Zarnowski MJ, Guerre-Millo M, de la Luz Sierra M, Taylor SI, Cushman SW 1993 Transfection of DNA into isolated rat adipose cells by electroporation: evaluation of promoter activity in transfected adipose cells which are highly responsive to insulin after one day in culture. Biochem Biophys Res Commun 194:338-346
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 338-346
    • Quon, M.J.1    Zarnowski, M.J.2    Guerre-Millo, M.3    De La Luz Sierra, M.4    Taylor, S.I.5    Cushman, S.W.6
  • 20
    • 0023553666 scopus 로고
    • A novel rapid assay for chloramphenicol acetyltransferase gene expression
    • Neuman JR, Morency CA, Russion KO 1987 A novel rapid assay for chloramphenicol acetyltransferase gene expression. Biotechniques 5:444-449
    • (1987) Biotechniques , vol.5 , pp. 444-449
    • Neuman, J.R.1    Morency, C.A.2    Russion, K.O.3
  • 21
    • 0029815091 scopus 로고    scopus 로고
    • Identification of functional elements of the chicken ∈-globin promoter involved in stage-specific interaction with the β/∈ enhancer
    • Mason MM, Grasso JA, Gavrilova O, Reitman M 1996 Identification of functional elements of the chicken ∈-globin promoter involved in stage-specific interaction with the β/∈ enhancer. J Biol Chem 271:25459-25467
    • (1996) J Biol Chem , vol.271 , pp. 25459-25467
    • Mason, M.M.1    Grasso, J.A.2    Gavrilova, O.3    Reitman, M.4
  • 22
    • 0028559221 scopus 로고
    • Enhancer activity of upstream hypersensitive site 2 of the chicken β-globin cluster is mediated by GATA sites
    • Abruzzo LV, Reitman M 1994 Enhancer activity of upstream hypersensitive site 2 of the chicken β-globin cluster is mediated by GATA sites. J Biol Chem 269:32565-32571
    • (1994) J Biol Chem , vol.269 , pp. 32565-32571
    • Abruzzo, L.V.1    Reitman, M.2
  • 23
    • 0025851174 scopus 로고
    • The mitochondrial uncoupling protein gene in brown fat: Correlation between DNase I hypersensitivity and expression in transgenic mice
    • Boyer BB, Kozak LP 1991 The mitochondrial uncoupling protein gene in brown fat: correlation between DNase I hypersensitivity and expression in transgenic mice. Mol Cell Biol 11:4147-4156
    • (1991) Mol Cell Biol , vol.11 , pp. 4147-4156
    • Boyer, B.B.1    Kozak, L.P.2
  • 24
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG 1983 Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 25
    • 0024728988 scopus 로고
    • Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes
    • Christy RJ, Yang VW, Ntambi JM, Geiman DE, Landschulz WH, Friedman AD, Nakabeppu Y, Kelly TJ, Lane MD 1989 Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes. Genes Dev 3:1323-1335
    • (1989) Genes Dev , vol.3 , pp. 1323-1335
    • Christy, R.J.1    Yang, V.W.2    Ntambi, J.M.3    Geiman, D.E.4    Landschulz, W.H.5    Friedman, A.D.6    Nakabeppu, Y.7    Kelly, T.J.8    Lane, M.D.9
  • 28
    • 46149139074 scopus 로고
    • Promoter-specific activation of RNA polymerase II transcription by Sp1
    • Kadonaga JT, Jones KA, Tjian R 1986 Promoter-specific activation of RNA polymerase II transcription by Sp1. Trends Biochem Sci 11:20-23
    • (1986) Trends Biochem Sci , vol.11 , pp. 20-23
    • Kadonaga, J.T.1    Jones, K.A.2    Tjian, R.3
  • 29
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR γ 2, a lipid-activated transcription factor
    • Tontonoz P, Hu E, Spiegelman BM 1994 Stimulation of adipogenesis in fibroblasts by PPAR γ 2, a lipid-activated transcription factor. Cell 79:1147-1156
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 30
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor α (PPAR α)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA 1995 An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor α (PPAR α). J Biol Chem 270:12953-12956
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 32
    • 0029894050 scopus 로고    scopus 로고
    • Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes
    • Kallen CB, Lazar MA 1996 Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes. Proc Natl Acad Sci USA 93:5793-5796
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5793-5796
    • Kallen, C.B.1    Lazar, M.A.2
  • 33
    • 0029795431 scopus 로고    scopus 로고
    • Effect of troglitazone on leptin production. Studies in vitro and in human subjects
    • Nolan JJ, Olefsky JM, Nyce MR, Considine RV, Caro JF 1996 Effect of troglitazone on leptin production. Studies in vitro and in human subjects. Diabetes 45:1276-1278
    • (1996) Diabetes , vol.45 , pp. 1276-1278
    • Nolan, J.J.1    Olefsky, J.M.2    Nyce, M.R.3    Considine, R.V.4    Caro, J.F.5
  • 36
    • 0028225462 scopus 로고
    • SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
    • Wang X, Sato R, Brown MS, Hua X, Goldstein JL 1994 SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77:53-62
    • (1994) Cell , vol.77 , pp. 53-62
    • Wang, X.1    Sato, R.2    Brown, M.S.3    Hua, X.4    Goldstein, J.L.5
  • 37
    • 0028360111 scopus 로고
    • Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1)
    • Sato R, Yang J, Wang X, Evans MJ, Ho YK, Goldstein JL, Brown MS 1994 Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1). J Biol Chem 269:17267-17273
    • (1994) J Biol Chem , vol.269 , pp. 17267-17273
    • Sato, R.1    Yang, J.2    Wang, X.3    Evans, M.J.4    Ho, Y.K.5    Goldstein, J.L.6    Brown, M.S.7
  • 38
    • 0029083859 scopus 로고
    • Increased obese mRNA expression in omental fat cells from massively obese humans
    • Hamilton BS, Paglia D, Kwan AY, Deitel M 1995 Increased obese mRNA expression in omental fat cells from massively obese humans. Nat Med 1:953-956
    • (1995) Nat Med , vol.1 , pp. 953-956
    • Hamilton, B.S.1    Paglia, D.2    Kwan, A.Y.3    Deitel, M.4
  • 39
    • 0030813619 scopus 로고    scopus 로고
    • Identification of a placental enhancer for the human leptin gene
    • Bi S, Gavrilova O, Gong D-W, Mason MM, Reitman M 1997 Identification of a placental enhancer for the human leptin gene. J Biol Chem 272:30583-30588
    • (1997) J Biol Chem , vol.272 , pp. 30583-30588
    • Bi, S.1    Gavrilova, O.2    Gong, D.-W.3    Mason, M.M.4    Reitman, M.5
  • 40
    • 0028980389 scopus 로고
    • C/EBP α: A critical regulator of genes governing integrative metabolic processes
    • Darlington GJ, Wang N, Hanson RW 1995 C/EBP α: a critical regulator of genes governing integrative metabolic processes. Curr Opin Genet Dev 5:565-570
    • (1995) Curr Opin Genet Dev , vol.5 , pp. 565-570
    • Darlington, G.J.1    Wang, N.2    Hanson, R.W.3
  • 42
    • 0028129499 scopus 로고
    • Ectopic expression of the CCAAT/ enhancer-binding protein a promotes the adipogenic program in a variety of mouse fibroblastic cells
    • Freytag SO, Paielli DL, Gilbert JD 1994 Ectopic expression of the CCAAT/ enhancer-binding protein a promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev 8:1654-1663
    • (1994) Genes Dev , vol.8 , pp. 1654-1663
    • Freytag, S.O.1    Paielli, D.L.2    Gilbert, J.D.3
  • 43
    • 0028564903 scopus 로고
    • CCAAT/enhancer binding protein a is sufficient to initiate the 3T3-L1 adipocyte differentiation program
    • Lin FT, Lane MD 1994 CCAAT/enhancer binding protein a is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci USA 91:8757-8761
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8757-8761
    • Lin, F.T.1    Lane, M.D.2
  • 45
    • 0029062839 scopus 로고
    • Transcriptional regulation of gene expression during adipocyte differentiation
    • MacDougald OA, Lane MD 1995 Transcriptional regulation of gene expression during adipocyte differentiation. Annu Rev Biochem 64:345-373
    • (1995) Annu Rev Biochem , vol.64 , pp. 345-373
    • MacDougald, O.A.1    Lane, M.D.2
  • 46
    • 0025177338 scopus 로고
    • Mouse insulin-responsive glucose transporter gene: Characterization of the gene and trans-activation by the CCAAT/enhancer binding protein
    • Kaestner KH, Christy RJ, Lane MD 1990 Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding protein. Proc Natl Acad Sci USA 87:251-255
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 251-255
    • Kaestner, K.H.1    Christy, R.J.2    Lane, M.D.3
  • 47
    • 0028140275 scopus 로고
    • A novel as-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP β and an Sp1 factor
    • Lee YH, Yano M, Liu SY, Matsunaga E, Johnson PF, Gonzalez FJ 1994 A novel as-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP β and an Sp1 factor. Mol Cell Biol 14:1383-1394
    • (1994) Mol Cell Biol , vol.14 , pp. 1383-1394
    • Lee, Y.H.1    Yano, M.2    Liu, S.Y.3    Matsunaga, E.4    Johnson, P.F.5    Gonzalez, F.J.6
  • 48
    • 0026029709 scopus 로고
    • CCAAT/enhancer binding protein gene promoter: Binding of nuclear factors during differentiation of 3T3-L1 preadipocytes
    • Christy RJ, Kaestner KH, Geiman DE, Lane MD 1991 CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci USA 88:2593-2597
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2593-2597
    • Christy, R.J.1    Kaestner, K.H.2    Geiman, D.E.3    Lane, M.D.4
  • 49
    • 0027304780 scopus 로고
    • CCAAT/enhancer binding protein α (C/ EBP α) undifferentiated protein: A developmentally regulated nuclear protein that binds to the C/EBP α gene promoter
    • Vasseur-Cognet M, Lane MD 1993 CCAAT/enhancer binding protein α (C/ EBP α) undifferentiated protein: a developmentally regulated nuclear protein that binds to the C/EBP α gene promoter. Proc Natl Acad Sci USA 90:7312-7316
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7312-7316
    • Vasseur-Cognet, M.1    Lane, M.D.2
  • 50
    • 0029059484 scopus 로고
    • Fatty genotype-induced increase in GLUT4 promoter activity in transfected adipocytes: Delineation of two faresponsive regions and glucose effect
    • Hainault, I, Hajduch E, Lavau M 1995 Fatty genotype-induced increase in GLUT4 promoter activity in transfected adipocytes: delineation of two faresponsive regions and glucose effect. Biochem Biophys Res Commun 209:1053-1061
    • (1995) Biochem Biophys Res Commun , vol.209 , pp. 1053-1061
    • Hainault, I.1    Hajduch, E.2    Lavau, M.3
  • 51
    • 0028815382 scopus 로고
    • Evidence of increased glyceraldehyde-3-phosphate dehydrogenase and fatty acid synthetase promoter activities in transiently transfected adipocytes from genetically obese rats
    • Rolland V, Dugail I, Le Liepvre X, Lavau M 1995 Evidence of increased glyceraldehyde-3-phosphate dehydrogenase and fatty acid synthetase promoter activities in transiently transfected adipocytes from genetically obese rats. J Biol Chem 270:1102-1106
    • (1995) J Biol Chem , vol.270 , pp. 1102-1106
    • Rolland, V.1    Dugail, I.2    Le Liepvre, X.3    Lavau, M.4
  • 52
    • 9544232631 scopus 로고    scopus 로고
    • A GC-rich region containing Sp1 and Sp1-like binding sites is a crucial regulatory motif for fatty acid synthase gene promoter activity in adipocytes. Implication in the over-activity of FAS promoter in obese Zucker rats
    • Rolland V, Liepvre XL, Jump DB, Lavau M, Dugail I 1996 A GC-rich region containing Sp1 and Sp1-like binding sites is a crucial regulatory motif for fatty acid synthase gene promoter activity in adipocytes. Implication In the over-activity of FAS promoter in obese Zucker rats. J Biol Chem 271:21297-21302
    • (1996) J Biol Chem , vol.271 , pp. 21297-21302
    • Rolland, V.1    Liepvre, X.L.2    Jump, D.B.3    Lavau, M.4    Dugail, I.5
  • 53
    • 0028263634 scopus 로고
    • Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein α and δ genes in 3T3-L1 adipocytes and white adipose tissue
    • MacDougald OA, Cornelius P, Lin FT, Chen SS, Lane MD 1994 Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein α and δ genes in 3T3-L1 adipocytes and white adipose tissue. J Biol Chem 269:19041-19047
    • (1994) J Biol Chem , vol.269 , pp. 19041-19047
    • MacDougald, O.A.1    Cornelius, P.2    Lin, F.T.3    Chen, S.S.4    Lane, M.D.5
  • 54
    • 0028950216 scopus 로고
    • Insulin regulates transcription of the CCAAT/enhancer binding protein (C/EBP) α, β, and δ genes in fully-differentiated 3T3-L1 adipocytes
    • MacDougald OA, Cornelius P, Liu R, Lane MD 1995 Insulin regulates transcription of the CCAAT/enhancer binding protein (C/EBP) α, β, and δ genes in fully-differentiated 3T3-L1 adipocytes. J Biol Chem 270:647-654
    • (1995) J Biol Chem , vol.270 , pp. 647-654
    • MacDougald, O.A.1    Cornelius, P.2    Liu, R.3    Lane, M.D.4
  • 55
    • 0029017604 scopus 로고
    • Induction of Sp1 phosphorylation and NF-kappa B-independent HIV promoter domain activity in T lymphocytes stimulated by okadaic acid
    • Vlach J, Garcia A, Jacque JM, Rodriguez MS, Michelson S, Virelizier JL 1995 Induction of Sp1 phosphorylation and NF-kappa B-independent HIV promoter domain activity in T lymphocytes stimulated by okadaic acid. Virology 208:753-761
    • (1995) Virology , vol.208 , pp. 753-761
    • Vlach, J.1    Garcia, A.2    Jacque, J.M.3    Rodriguez, M.S.4    Michelson, S.5    Virelizier, J.L.6
  • 56
    • 0028789622 scopus 로고
    • Sp1 is phosphorylated and its DNA binding activity down-regulated upon terminal differentiation of the liver
    • Leggett RW, Armstrong SA, Barry D, Mueller CR 1995 Sp1 is phosphorylated and its DNA binding activity down-regulated upon terminal differentiation of the liver. J Biol Chem 270:25879-25884
    • (1995) J Biol Chem , vol.270 , pp. 25879-25884
    • Leggett, R.W.1    Armstrong, S.A.2    Barry, D.3    Mueller, C.R.4
  • 58
    • 0028972025 scopus 로고
    • 15-Deoxy-Δ2,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR γ
    • Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM 1995 15-Deoxy-Δ2,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR γ. Cell 83:803-812
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 59
    • 0026517010 scopus 로고
    • Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer C, Krey G, Keller H, Givel F, Helftenbein G, Wahli W 1992 Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell 68:879-887
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1    Krey, G.2    Keller, H.3    Givel, F.4    Helftenbein, G.5    Wahli, W.6
  • 61
    • 0025270737 scopus 로고
    • Nuclear receptor that identifies a novel retinoic acid response pathway
    • Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM 1990 Nuclear receptor that identifies a novel retinoic acid response pathway. Nature 345:224-229
    • (1990) Nature , vol.345 , pp. 224-229
    • Mangelsdorf, D.J.1    Ong, E.S.2    Dyck, J.A.3    Evans, R.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.