Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin

Circulation

Volumn 100, Issue 25, 1999, Pages 2473-2476

  Ouchi, Noriyuki ^a,b   Kihara, Shinji ^a   Arita, Yukio ^a   Maeda, Kazuhisa ^a   Kuriyama, Hiroshi ^a   Okamoto, Yoshihisa ^a   Hotta, Kikuko ^a   Nishida, Makoto ^a   Takahashi, Masahiko ^a   Nakamura, Tadashi ^a   Yamashita, Shizuya ^a   Funahashi, Tohru ^a   Matsuzawa, Yuji ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Adiponectin; Cell adhesion molecules; Coronary disease; Endothelium

Indexed keywords

CELL ADHESION MOLECULE; DRUG VEHICLE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; PLASMA PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ADIPOCYTE; ANTIGEN EXPRESSION; ARTICLE; CARDIOVASCULAR DISEASE; CELL ADHESION; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY RISK; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; MALE; MONOCYTE; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT;

EID: 0033613545     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.100.25.2473     Document Type: Article

References (15)

1. Matsuzawa Y, Nakamura T, Shimomura I, Kotani K. Visceral fat accumulation and cardiovascular disease. Obes Res. 1995;3(suppl 5): 645S-647S.
2. Jensen NS. Obesity and cardiovascular disease: is body structure a factor? Curr Opin Lipidol. 1997;8:200-204.
3. Nakamura T, Tokunaga K, Shimomura I, Nishida M, Yoshida S, Kotani K, Islam AHM, Keno Y, Kobatake T, Nagai Y, Fujioka S, Tarui S, Matsuzawa Y. Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men. Atherosclerosis. 1994;107:239-246.
4. Maeda K, Okubo K, Shimomura I, Mizuno K, Matsuzawa Y, Matsubara K. Analysis of an expression profile of genes in the human adipose tissue. Gene. 1997;190:227-235.
5. Spiegelman BM, Choy L, Hotamisligil GS, Graves R, Tontonoz P. Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes. J Biol Chem. 1993;268:6823-6826.
6. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994;372:425-432.
7. Shimomura I, Funahashi T, Takahashi M, Maeda K, Kotani K, Nakamura T, Yamashita S, Miura M, Fukuda Y, Takemura K, Tokunaga K, Matsuzawa Y. Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med. 1996;2:800-803.
8. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259:87-91.
9. Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apMl (adipose most abundant gene transcript 1). Biochem Biophys Res Commun. 1996;221:286-289.
10. Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun. 1999; 257:79-83.
11. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
12. Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 1991;251: 788-791.
13. Davies MJ, Gordon JL, Gearing AJ, Pigott R, Woolf N, Katz D, Kyriakopoulos A. The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis. J Pathol. 1993;171:223-229.
14. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 1994;76:301-314.
15. Vora DK, Fang ZT, Liva SM, Tyner TR, Parhami F, Watson AD, Drake TA, Territo MC, Berliner JA. Induction of P-selectin by oxidized lipoproteins: separate effects on synthesis and surface expression. Circ Res. 1997;80:810-818.