α-Linolenic acid suppresses cholesterol and triacylglycerol biosynthesis pathway by suppressing SREBP-2, SREBP-1a and -1c expression

Cytotechnology

Volumn 65, Issue 6, 2013, Pages 899-907

  Fukumitsu, Satoshi ^a,b   Villareal, Myra O ^b   Onaga, Shoko ^b   Aida, Kazuhiko ^a   Han, Junkyu ^b   Isoda, Hiroko ^b  

^a Kanagawa 243 0041   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Linolenic acid; Adipocyte; Cholesterol biosynthesis; n 3 Polyunsaturated fatty acid; Triacylglycerol biosynthesis

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1A; CHOLESTEROL; DNA; FATTY ACID SYNTHASE; LEPTIN; LINOLENIC ACID; LIPID; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; CELL DIFFERENTIATION; CELL STRAIN 3T3; CHOLESTEROL SYNTHESIS; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; DNA MICROARRAY; DRUG EFFECT; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENE EXPRESSION; INTRACELLULAR MEMBRANE; LIPID METABOLISM; LIPID TRANSPORT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

EID: 84891034184     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-012-9510-x     Document Type: Conference Paper

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