-
1
-
-
0031984952
-
Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats
-
Anai M., Funaki M., Ogihara T., Terasaki J., Inukai K., Katagiri H., Fukushima Y., Yazaki Y., Kikuchi M., Oka Y., Asano T. Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats. Diabetes. 47:1998;13-23.
-
(1998)
Diabetes
, vol.47
, pp. 13-23
-
-
Anai, M.1
Funaki, M.2
Ogihara, T.3
Terasaki, J.4
Inukai, K.5
Katagiri, H.6
Fukushima, Y.7
Yazaki, Y.8
Kikuchi, M.9
Oka, Y.10
Asano, T.11
-
2
-
-
0026953735
-
Muscle glucose transport, GLUT4 content and degree of exercise training in obese Zucker rats
-
Banks E.A., Brozinick J.T. Jr., Yaspelkis B.B. III, Kang H.Y., Ivy J.L. Muscle glucose transport, GLUT4 content and degree of exercise training in obese Zucker rats. Am. J. Physiol. Endocrinol. Metab. 263:1992;E1010-E1015.
-
(1992)
Am. J. Physiol. Endocrinol. Metab.
, vol.263
-
-
Banks, E.A.1
Brozinick Jr., J.T.2
Yaspelkis III, B.B.3
Kang, H.Y.4
Ivy, J.L.5
-
3
-
-
0031944104
-
Diet-induced insulin resistance precedes other aspects of the metabolic syndrome
-
Barnard R.J., Roberts C.K., Varon S.M., Berger J.J. Diet-induced insulin resistance precedes other aspects of the metabolic syndrome. J. Appl. Physiol. 84(4):1998;1311-1315.
-
(1998)
J. Appl. Physiol.
, vol.84
, Issue.4
, pp. 1311-1315
-
-
Barnard, R.J.1
Roberts, C.K.2
Varon, S.M.3
Berger, J.J.4
-
4
-
-
0031439778
-
Leptin selectively decreases visceral adiposity and enhances insulin action
-
Barzilai N., Wang J., Massilon D., Vuguin P., Hawkins M., Rossetti L. Leptin selectively decreases visceral adiposity and enhances insulin action. J. Clin. Invest. 100(12):1997;3105-3110.
-
(1997)
J. Clin. Invest.
, vol.100
, Issue.12
, pp. 3105-3110
-
-
Barzilai, N.1
Wang, J.2
Massilon, D.3
Vuguin, P.4
Hawkins, M.5
Rossetti, L.6
-
6
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
7
-
-
0027425174
-
Effects of exercise training on muscle GLUT4 protein content and translocation in obese Zucker rats
-
Brozinick J.T. Jr., Etgen G.J. Jr., Yaspelkis B.B. III, Kang H.Y., Ivy J.L. Effects of exercise training on muscle GLUT4 protein content and translocation in obese Zucker rats. Am. J. Physiol. Endocrinol. Metab. 265:1993;E419-E427.
-
(1993)
Am. J. Physiol. Endocrinol. Metab.
, vol.265
-
-
Brozinick Jr., J.T.1
Etgen Jr., G.J.2
Yaspelkis III, B.B.3
Kang, H.Y.4
Ivy, J.L.5
-
8
-
-
0034061685
-
Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia
-
Buettner R., Newgard C.B., Rhodes C.J., O'Doherty R.M. Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia. Am. J. Physiol. Endocrinol. Metabol. 278:2000;E563-E569.
-
(2000)
Am. J. Physiol. Endocrinol. Metabol.
, vol.278
-
-
Buettner, R.1
Newgard, C.B.2
Rhodes, C.J.3
O'Doherty, R.M.4
-
9
-
-
0035914388
-
Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
-
Cho H., Thorvaldsen J.L., Chu Q., Feng F., Birnbaum M.J. Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem. 276(42):2001;38349-38352.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.42
, pp. 38349-38352
-
-
Cho, H.1
Thorvaldsen, J.L.2
Chu, Q.3
Feng, F.4
Birnbaum, M.J.5
-
10
-
-
0036081022
-
Glucose transport rate and glycogen synthase activity both limit skeletal muscle glycogen accumulation
-
Fisher J.S., Nolte L.A., Kawanaka K., Han D.H., Jones T.E., Holloszy J.O. Glucose transport rate and glycogen synthase activity both limit skeletal muscle glycogen accumulation. Am. J. Physiol. Endocrinol. Metabol. 282:2002;E1214-E1221.
-
(2002)
Am. J. Physiol. Endocrinol. Metabol.
, vol.282
-
-
Fisher, J.S.1
Nolte, L.A.2
Kawanaka, K.3
Han, D.H.4
Jones, T.E.5
Holloszy, J.O.6
-
11
-
-
0025299343
-
Exercise training increases glucose transporter GLUT-4 in skeletal muscle of obese Zucker (fa/fa) rats
-
Friedman J.E., Sherman W.M., Reed M.J., Elton C.W., Dohm G.L. Exercise training increases glucose transporter GLUT-4 in skeletal muscle of obese Zucker (fa/fa) rats. FEBS Lett. 268:1990;13-16.
-
(1990)
FEBS Lett.
, vol.268
, pp. 13-16
-
-
Friedman, J.E.1
Sherman, W.M.2
Reed, M.J.3
Elton, C.W.4
Dohm, G.L.5
-
12
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas J.L., Gajiwala K.S., Maffei M., Cohen S.L., Chait B.T., Rabinowitz D., Lallone R.L., Burley S.K., Friedman J.F. Weight-reducing effects of the plasma protein encoded by the obese gene. Science. 269:1995;543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.F.9
-
13
-
-
0033667852
-
Limitation to basal and insulin-stimulated skeletal muscle glucose uptake in the high-fat-fed rat
-
Halseth A.E., Bracy D.P., Wasserman D.H. Limitation to basal and insulin-stimulated skeletal muscle glucose uptake in the high-fat-fed rat. Am. J. Physiol. Endocrinol. Metab. 279:2000;E1064-E1071.
-
(2000)
Am. J. Physiol. Endocrinol. Metab.
, vol.279
-
-
Halseth, A.E.1
Bracy, D.P.2
Wasserman, D.H.3
-
14
-
-
3543121117
-
A high fat diet impairs stimulation of glucose transport in muscle. Functional evaluation of potential mechanisms
-
Hansen P.A., Han D.H., Marshall B.A., Nolte L.A., Chen M.M., Mueckler M., Holloszy J.O. A high fat diet impairs stimulation of glucose transport in muscle. Functional evaluation of potential mechanisms. J. Biol. Chem. 273(40):1998;26157-26163.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.40
, pp. 26157-26163
-
-
Hansen, P.A.1
Han, D.H.2
Marshall, B.A.3
Nolte, L.A.4
Chen, M.M.5
Mueckler, M.6
Holloszy, J.O.7
-
15
-
-
0013856940
-
L(+)lactic acid and the steady state of cellular red/ox-systems
-
Hohorst H.J., Arese P., Bartels H., Stratmann D., Talke H. L(+)lactic acid and the steady state of cellular red/ox-systems. Ann. NY Acad. Sci. 119:1965;974-994.
-
(1965)
Ann. NY Acad. Sci.
, vol.119
, pp. 974-994
-
-
Hohorst, H.J.1
Arese, P.2
Bartels, H.3
Stratmann, D.4
Talke, H.5
-
16
-
-
0024347560
-
Skeletal muscle glucose transport in obese Zucker rats after exercise training
-
Ivy J.L., Brozinick J.T. Jr., Torgan C.E., Kastello G.M. Skeletal muscle glucose transport in obese Zucker rats after exercise training. J. Appl. Physiol. 66:1989;2635-2641.
-
(1989)
J. Appl. Physiol.
, vol.66
, pp. 2635-2641
-
-
Ivy, J.L.1
Brozinick Jr., J.T.2
Torgan, C.E.3
Kastello, G.M.4
-
18
-
-
0032698470
-
Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes
-
Kim Y.-B., Nikoulina S.E., Ciaraldi T.P., Henry R.R., Kahn B.K. Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes. J. Clin. Invest. 104:1999;733-741.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 733-741
-
-
Kim, Y.-B.1
Nikoulina, S.E.2
Ciaraldi, T.P.3
Henry, R.R.4
Kahn, B.K.5
-
19
-
-
0030720085
-
Tissue triglycerides, insulin resistance, and insulin production: Implications for hyperinsulinemia of obesity
-
Koyama K., Chen G., Lee Y., Unger R.H. Tissue triglycerides, insulin resistance, and insulin production: implications for hyperinsulinemia of obesity. Am. J. Physiol. Endocrinol. Metab. 273:1997;E708-E713.
-
(1997)
Am. J. Physiol. Endocrinol. Metab.
, vol.273
-
-
Koyama, K.1
Chen, G.2
Lee, Y.3
Unger, R.H.4
-
20
-
-
0022628695
-
In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: Assessment by euglycaemic clamp plus deoxyglucose administration
-
Kraegen E.W., James D.E., Storlein L.H., Burleigh K.M., Chisholm D.J. In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: assessment by euglycaemic clamp plus deoxyglucose administration. Diabetologia. 29(3):1986;192-198.
-
(1986)
Diabetologia
, vol.29
, Issue.3
, pp. 192-198
-
-
Kraegen, E.W.1
James, D.E.2
Storlein, L.H.3
Burleigh, K.M.4
Chisholm, D.J.5
-
21
-
-
0343314906
-
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients
-
Krook A., Bjornholm M., Galuska D., Jiang X.J., Fahlman R., Myers M.G. Jr., Wallberg-Henriksson H., Zierath J.R. Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients. Diabetes. 49:2000;284-292.
-
(2000)
Diabetes
, vol.49
, pp. 284-292
-
-
Krook, A.1
Bjornholm, M.2
Galuska, D.3
Jiang, X.J.4
Fahlman, R.5
Myers Jr., M.G.6
Wallberg-Henriksson, H.7
Zierath, J.R.8
-
22
-
-
0031852665
-
Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
-
Krook A., Roth R.A., Jiang X.J., Zierath J.R., Wallberg-Henriksson H. Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects. Diabetes. 47:1998;1281-1286.
-
(1998)
Diabetes
, vol.47
, pp. 1281-1286
-
-
Krook, A.1
Roth, R.A.2
Jiang, X.J.3
Zierath, J.R.4
Wallberg-Henriksson, H.5
-
23
-
-
0036148471
-
Fatty acid-induced insulin resistance: Decreased muscle PI3K activation but unchanged Akt phosphorylation
-
Kruszynska Y.T., Worrall D.S., Ofrecio J., Frias J.P., Macaraeg G., Olefsky J.M. Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation. J. Clin. Endocrinol. Metabol. 87(1):2002;226-234.
-
(2002)
J. Clin. Endocrinol. Metabol.
, vol.87
, Issue.1
, pp. 226-234
-
-
Kruszynska, Y.T.1
Worrall, D.S.2
Ofrecio, J.3
Frias, J.P.4
MacAraeg, G.5
Olefsky, J.M.6
-
24
-
-
0014738371
-
Determination of glycogen in small tissue samples
-
Lo S., Russell J.C., Taylor A.W. Determination of glycogen in small tissue samples. J. Appl. Physiol. 28:1970;234-236.
-
(1970)
J. Appl. Physiol.
, vol.28
, pp. 234-236
-
-
Lo, S.1
Russell, J.C.2
Taylor, A.W.3
-
25
-
-
1842405349
-
Leptin directly alters lipid partitioning in skeletal muscle
-
Muoio D.M., Dohm G.L., Fiedorek F.T. Jr., Tapscott E.B., Coleman R.A. Leptin directly alters lipid partitioning in skeletal muscle. Diabetes. 46:1997;1360-1363.
-
(1997)
Diabetes
, vol.46
, pp. 1360-1363
-
-
Muoio, D.M.1
Dohm, G.L.2
Fiedorek Jr., F.T.3
Tapscott, E.B.4
Coleman, R.A.5
-
26
-
-
0035658486
-
Normal Akt/PKB with reduced PI3K activation in insulin-resistant mice
-
Nadler S.T., Stoehr J.P., Rabaglia M.E., Schueler K.L., Birnbaum M.J., Attie A.D. Normal Akt/PKB with reduced PI3K activation in insulin-resistant mice. Am J Physiol Endocrinol Metab. 281:2001;E1249-E1254.
-
(2001)
Am J Physiol Endocrinol Metab.
, vol.281
-
-
Nadler, S.T.1
Stoehr, J.P.2
Rabaglia, M.E.3
Schueler, K.L.4
Birnbaum, M.J.5
Attie, A.D.6
-
27
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pellymounter M.A., Cullen M.J., Baker M.B., Hecht R., Winters D., Boone T., Collins F. Effects of the obese gene product on body weight regulation in ob/ob mice. Science. 269:1995;540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pellymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
28
-
-
0015117034
-
Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism
-
Ruderman N.B., Houghton C.R.S., Helms R. Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism. Biochem. J. 124:1971;639-651.
-
(1971)
Biochem. J.
, vol.124
, pp. 639-651
-
-
Ruderman, N.B.1
Houghton, C.R.S.2
Helms, R.3
-
29
-
-
0141459344
-
High-fat diet and leptin treatment alter skeletal muscle insulin-stimulated phosphatidylinositol 3-kinase activity and glucose transport
-
Singh M.K., Krisan A.D., Crain A.M., Collins D.E., Yaspelkis B.B. III High-fat diet and leptin treatment alter skeletal muscle insulin-stimulated phosphatidylinositol 3-kinase activity and glucose transport. Metabol. 52(9):2003;1196-1205.
-
(2003)
Metabol.
, vol.52
, Issue.9
, pp. 1196-1205
-
-
Singh, M.K.1
Krisan, A.D.2
Crain, A.M.3
Collins, D.E.4
Yaspelkis III, B.B.5
-
30
-
-
0030737573
-
Effects of leptin on insulin sensitivity in normal rats
-
Sivitz W.I., Walsh S.A., Morgan D.A., Thomas M.J., Haynes W.G. Effects of leptin on insulin sensitivity in normal rats. Endocrinol. 138(8):1997;3395-3401.
-
(1997)
Endocrinol.
, vol.138
, Issue.8
, pp. 3395-3401
-
-
Sivitz, W.I.1
Walsh, S.A.2
Morgan, D.A.3
Thomas, M.J.4
Haynes, W.G.5
-
31
-
-
0005828771
-
Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats
-
Song X.M., Kawano Y., Krook A., Ryder J.W., Efendic S., Roth R.A., Wallberg-Henriksson H., Zierath J.R. Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats. Diabetes. 48:1999;664-670.
-
(1999)
Diabetes
, vol.48
, pp. 664-670
-
-
Song, X.M.1
Kawano, Y.2
Krook, A.3
Ryder, J.W.4
Efendic, S.5
Roth, R.A.6
Wallberg-Henriksson, H.7
Zierath, J.R.8
-
32
-
-
0037088653
-
Chronic leptin treatment decreases fatty acid uptake and fatty acid transporters in rat skeletal muscle
-
Steinberg G.R., Dyck D.J., Calles-Escandon J., Tandon N.N., Luiken J.J.F.P., Glatz J.F.C., Bonen A. Chronic leptin treatment decreases fatty acid uptake and fatty acid transporters in rat skeletal muscle. J. Biol. Chem. 277:2002;8854-8860.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8854-8860
-
-
Steinberg, G.R.1
Dyck, D.J.2
Calles-Escandon, J.3
Tandon, N.N.4
Luiken, J.J.F.P.5
Glatz, J.F.C.6
Bonen, A.7
-
33
-
-
0034091792
-
Selective interaction between leptin and insulin signaling pathways in a hepatic cell line
-
Szanto I., Kahn C.R. Selective interaction between leptin and insulin signaling pathways in a hepatic cell line. Proc. Natl. Acad. Sci. 97:2000;2355-2360.
-
(2000)
Proc. Natl. Acad. Sci.
, vol.97
, pp. 2355-2360
-
-
Szanto, I.1
Kahn, C.R.2
-
35
-
-
0025014823
-
Intracellular glucose oxidation and glycogen synthase activity are reduced in non-insulin-dependent (Type II) diabetes independent of impaired glucose uptake
-
Thorburn A.W., Gumbiner B., Bulacan F., Wallace P., Henry R.R. Intracellular glucose oxidation and glycogen synthase activity are reduced in non-insulin-dependent (Type II) diabetes independent of impaired glucose uptake. J. Clin. Invest. 85:1990;522-529.
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 522-529
-
-
Thorburn, A.W.1
Gumbiner, B.2
Bulacan, F.3
Wallace, P.4
Henry, R.R.5
-
36
-
-
0035432971
-
Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/Protein Kinase B and atypical Protein Kinase C (ζ/λ) activities
-
Tremblay F., Lavigne C., Jacques H., Marette A. Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/Protein Kinase B and atypical Protein Kinase C (ζ/λ) activities. Diabetes. 50:2001;1901-1910.
-
(2001)
Diabetes
, vol.50
, pp. 1901-1910
-
-
Tremblay, F.1
Lavigne, C.2
Jacques, H.3
Marette, A.4
-
37
-
-
0033306791
-
Differential effects of leptin in regulation of tissue glucose utilization in vivo
-
Wang J.L., Chinookoswong N., Scully S., Qi M., Shi Z.Q. Differential effects of leptin in regulation of tissue glucose utilization in vivo. Endocrinol. 140:1999;2117-2124.
-
(1999)
Endocrinol.
, vol.140
, pp. 2117-2124
-
-
Wang, J.L.1
Chinookoswong, N.2
Scully, S.3
Qi, M.4
Shi, Z.Q.5
-
38
-
-
0031741575
-
A modified high-fat diet induces insulin resistance in rat skeletal muscle but not adipocytes
-
Wilkes J.J., Bonen A., Bell R.C. A modified high-fat diet induces insulin resistance in rat skeletal muscle but not adipocytes. Am. J. Physiol. Endocrinol. Metab. 275:1998;E679-E686.
-
(1998)
Am. J. Physiol. Endocrinol. Metab.
, vol.275
-
-
Wilkes, J.J.1
Bonen, A.2
Bell, R.C.3
-
39
-
-
0032948427
-
Chronic leptin administration increases insulin-stimulated skeletal muscle glucose uptake and transport
-
Yaspelkis B.B. III, Ansari L., Ramey E.A., Loy S.F. Chronic leptin administration increases insulin-stimulated skeletal muscle glucose uptake and transport. Metabol. 48(5):1999;671-676.
-
(1999)
Metabol.
, vol.48
, Issue.5
, pp. 671-676
-
-
Yaspelkis III, B.B.1
Ansari, L.2
Ramey, E.A.3
Loy, S.F.4
-
40
-
-
0035013923
-
Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats
-
Yaspelkis B.B. III, Davis J.R., Saberi M., Smith T.L., Jazayeri R., Singh M., Fernandez V., Trevino B., Chinookoswong N., Wang J., Shi Z.Q., Levin N. Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats. Am. J. Physiol. Endocrinol. Metab. 280:2001;E130-E142.
-
(2001)
Am. J. Physiol. Endocrinol. Metab.
, vol.280
-
-
Yaspelkis III, B.B.1
Davis, J.R.2
Saberi, M.3
Smith, T.L.4
Jazayeri, R.5
Singh, M.6
Fernandez, V.7
Trevino, B.8
Chinookoswong, N.9
Wang, J.10
Shi, Z.Q.11
Levin, N.12
-
41
-
-
0036062215
-
Chronic leptin treatment normalizes basal glucose transport in a fiber type-specific manner in high-fat-fed rats
-
Yaspelkis B.B. III, Saberi M., Singh M.K., Trevino B., Smith T.L. Chronic leptin treatment normalizes basal glucose transport in a fiber type-specific manner in high-fat-fed rats. Metabol. 51(7):2002;859-863.
-
(2002)
Metabol.
, vol.51
, Issue.7
, pp. 859-863
-
-
Yaspelkis III, B.B.1
Saberi, M.2
Singh, M.K.3
Trevino, B.4
Smith, T.L.5
-
42
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature. 372:1994;425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
43
-
-
0030987889
-
High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect
-
Zierath J.R., Houseknecht K.L., Gnudi L., Kahn B.B. High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect. Diabetes. 46(2):1997;215-223.
-
(1997)
Diabetes
, vol.46
, Issue.2
, pp. 215-223
-
-
Zierath, J.R.1
Houseknecht, K.L.2
Gnudi, L.3
Kahn, B.B.4
|