5-Hydroxy-eicosapentaenoic acid is an endogenous GPR119 agonist and enhances glucose-dependent insulin secretion

Biochemical and Biophysical Research Communications

Volumn 416, Issue 1-2, 2011, Pages 58-63

  Kogure, Ryouta ^a   Toyama, Kazuya ^a   Hiyamuta, Shuichi ^b   Kojima, Itaru ^a   Takeda, Shigeki ^a  

^a GUNMA UNIVERSITY   (Japan)

^b IDEMITSU KOSAN CO LTD   (Japan)

Author keywords

5 HEPE; G protein coupled receptor; GLP 1; GPR119; Insulin; Omega 3 unsaturated fatty acids

Indexed keywords

5 HYDROXY EICOSAPENTAENOIC ACID; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 119; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; ICOSAPENTAENOIC ACID; INSULIN; OMEGA 3 FATTY ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; HUMAN; HUMAN CELL; INSULIN RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION;

ANIMALS; CELL LINE, TUMOR; CYCLIC AMP; DIABETES MELLITUS; EICOSAPENTAENOIC ACID; GLUCOSE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MICE; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING;

EID: 83055184091     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.10.141     Document Type: Article

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