Ion channels and transporters as therapeutic targets in the pulmonary circulation

Pharmacology and Therapeutics

Volumn 144, Issue 3, 2014, Pages 349-368

  Olschewski, Andrea ^a,b   Papp, Rita ^a   Nagaraj, Chandran ^a   Olschewski, Horst ^a,b  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Endothelin receptor antagonists; Ion channels; Prostacyclin; Pulmonary hypertension; Soluble guanylate cyclase stimulators; Sympathetic neurotransmitter

Indexed keywords

ANESTHETIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; CALSEQUESTRIN; CHLORIDE CHANNEL; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; GUANYLATE CYCLASE ACTIVATOR; ILOPROST; ION CHANNEL; NEUROTRANSMITTER; NITRIC OXIDE; PHOSPHODIESTERASE INHIBITOR; PHOSPHOLAMBAN; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNQ; PROSTACYCLIN; PROTEIN TYROSINE KINASE; SEROTONIN; SEROTONIN ANTAGONIST; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TREPROSTINIL; UNINDEXED DRUG; VANILLOID RECEPTOR 4; VASOACTIVE INTESTINAL POLYPEPTIDE; VOLTAGE GATED CALCIUM CHANNEL; AGENTS AFFECTING WATER, MOLECULE OR ION TRANSPORT; ION TRANSPORT;

ANTIPROLIFERATIVE ACTIVITY; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CELL ORGANELLE; DRUG TARGETING; HUMAN; HYPERPOLARIZATION; HYPOXIA; LUNG BLOOD VESSEL; LUNG CIRCULATION; LUNG VASCULAR RESISTANCE; LUNG VASOCONSTRICTION; MEMBRANE STEADY POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PATHOPHYSIOLOGY; PULMONARY ARTERY; PULMONARY HYPERTENSION; REPOLARIZATION; REVIEW; SMOOTH MUSCLE FIBER; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; HYPERTENSION, PULMONARY; ION TRANSPORT; METABOLISM; MOLECULARLY TARGETED THERAPY; VASCULAR REMODELING;

HUMANS; HYPERTENSION, PULMONARY; ION CHANNELS; ION PUMPS; MEMBRANE TRANSPORT MODULATORS; MOLECULAR TARGETED THERAPY; PULMONARY CIRCULATION; VASCULAR REMODELING;

EID: 84910040051     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2014.08.001     Document Type: Review

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