Reversal of chronic hypoxia-induced alterations in pulmonary artery smooth muscle electromechanical coupling upon air breathing

Cardiovascular Research

Volumn 53, Issue 4, 2002, Pages 1019-1028

  Bonnet, Sébastien ^a   Dubuis, Eric ^b   Vandier, Christophe ^b   Martin, Stéphanie ^b   Marthan, Roger ^a   Savineau, Jean Pierre ^a  

^a INSERM   (France)

^b UNIVERSITÉ DE TOURS   (France)

Author keywords

Arteries; Hypertension; Hypoxia anoxia; K channel; Pulmonary circulation

Indexed keywords

4 AMINOPYRIDINE; CALCIUM; POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY MUSCLE; ARTERY TONE; ARTICLE; BREATHING; CALCIUM CELL LEVEL; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; DEPOLARIZATION; EXCITATION CONTRACTION COUPLING; HYPERSENSITIVITY; HYPOBARISM; HYPOXIA; MALE; MICROELECTRODE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER;

4-AMINOPYRIDINE; ANIMALS; ANOXIA; BLOOD PRESSURE; CALCIUM; CELLS, CULTURED; CHRONIC DISEASE; ELECTROPHYSIOLOGY; HOMEOSTASIS; HYPERTENSION, PULMONARY; MALE; MEMBRANE POTENTIALS; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; PULMONARY ARTERY; RATS; RATS, WISTAR;

EID: 0036199403     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(01)00548-X     Document Type: Article

References (37)

1. Physiological effects of high altitude on the pulmonary circulation
2. Rat pulmonary circulation after chronic hypoxia: Hemodynamic and structural features
3. Effects of chronic hypoxia on structure and reactivity of rat lung microvessels
4. Cellular and molecular mechanisms of pulmonary vascular remodeling
5. Persistence, re expression, and induction of pulmonary arterial fibronectin, tropoelastin, and type 1 procollagen mRNA expression in neonatal hypoxic pulmonary hypertension
6. Alterations in structure of elastic laminae of rat pulmonary arteries in hypoxic hypertension
7. Pathophysiology and clinical effects of chronic hypoxia
8. Influence of chronic hypoxia on the contributions of non-inactivating and delayed rectifier K currents to the resting potential and tone of rat pulmonary artery smooth muscle
9. Membrane potential-dependent and independent vasodilation in small pulmonaries arteries from chronically hypoxic rats
10. Chronic hypoxia-induced spontaneous and rhythmic contractions in the rat main pulmonary artery
11. i, and ET-1-induced responses in chronically hypoxic pulmonary myocytes
12. Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction
13. + current in rat pulmonary artery muscle cells
14. + channel α subunits in pulmonary artery smooth muscle cells
15. + currents in pulmonary arterial myocytes
16. v channel expression and function in pulmonary artery myocytes
17. + channels
18. + current that is active at resting potential in rabbit pulmonary artery smooth muscle cells
19. Regression of hypoxic hypertension-induced changes in the elastic laminea of rat pulmonary arteries
20. Modulation of angiotensin II receptor expression during development and regression of hypoxic pulmonary hypertension
21. Inhibition of tissue angiotensin-converting enzyme with quinapril reduces hypoxic pulmonary hypertension and pulmonary vascular remodeling
22. 2+-oscillations in vascular myocytes from the rat pulmonary artery
23. Enzymatic isolation and characterization of single vascular smooth muscle cells from cremaster arterioles
24. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
25. Purification and characterization of a unique, potent, peptidyl probe for high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamalus
26. 2+ indicators with greatly improved fluorescence properties
27. 2+ dependence and physiological implication
28. Influence of temperature on contractile activation and isometric force production in mechanically skinned muscle fibers of the frog
29. Effect of chronic hypoxia on agonist-induced tone and calcium signaling in rat pulmonary artery
30. + channel in oxygen sensitive pulmonary artery myocytes
31. + channels, Kv1.5 and Kv2.1 in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes
32. Alterations in a redox oxygen sensing mechanism in chronic hypoxia
33. Potential role for Kv3.1b channels as oxygen sensors
34. Mechanisms by which oxygen regulates gene expression and cell-cell interaction in vasculature
35. 2 tension
36. Cellular mechanisms of oxygen sensing
37. Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia