Localization and distribution of endothelin receptor subtypes in pulmonary vasculature of normal and hypoxia-exposed rats

American Journal of Respiratory Cell and Molecular Biology

Volumn 20, Issue 4, 1999, Pages 620-630

  Soma, Sanae ^a   Takahashi, Hideki ^a   Muramatsu, Masashi ^a   Oka, Masahiko ^a   Fukuchi, Yoshinosuke ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR;

ANIMAL; ANOXIA; ARTICLE; BIOSYNTHESIS; BRONCHUS; DNA PROBE; GENETICS; INTIMA; LUNG; LUNG ALVEOLUS; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PULMONARY ARTERY; RAT; SMOOTH MUSCLE; SPRAGUE DAWLEY RAT; TUNICA MEDIA; UPREGULATION; VASCULARIZATION;

ANIMALS; ANOXIA; BRONCHI; DNA PROBES; LUNG; MALE; MUSCLE, SMOOTH; PULMONARY ALVEOLI; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; TUNICA INTIMA; TUNICA MEDIA; UP-REGULATION;

EID: 0033110922     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.20.4.3356     Document Type: Article

References (36)

1. Levine, E. R. 1995. Endothelins. N. Engl. J. Med. 333:356-363.
2. Michael, J. R., and B. A. Markewitz. 1996. Endothelins and the lung. Am. J. Respir. Crit. Care Med. 154:555-581.
3. Haussoun, P. M., V. Thappa, M. J. Landman, and B. L. Fanburg. 1992. Endothelin 1: mitogenic activity on pulmonary artery smooth muscle cells and release from hypoxic endothelial cells. Proc. Soc. Exp. Biol. Med. 199:165-170.
4. Janakidevi, K. M., A. Fisher, P. J. Del Vecchio, C. Tiruppathi, J. Figge, and A. B. Malik. 1992. Endothelin-1 stimulates DNA synthesis and proliferation of pulmonary artery smooth muscle cells. Am. J. Physiol. 263:C1295-C1301.
5. Zamora, M. R., E. C. Dempsey, S. J. Walchak, and T. J. Stelzner. 1993. BQ123, an ETA receptor antagonist, inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 9:429-433.
6. Shymala, V., T. H. M. Moulthrop, J. Stratton-Thomas, and P. Tekamp-Olson. 1994. Two distinct human endothelin B receptors generated by alternative splicing from a single gene. Cell. Mol. Biol. Res. 40:285-296.
7. Power, R. F., J. Wharton, Y. Zhao, S. R. Bloom, and J. M. Polak. 1989. Autoradiographic localization of endothelin-1 binding sites in the cardiovascular and respiratory system. J. Cardiovasc. Pharmacol. 13(Suppl. 5):S50-S56.
8. 1.3.11.15] ET-1. Biochem. Biophys. Res. Commun. 182:144-150.
9. Durham, S. K., N. L. Goller, J. S. Lynch, S. M. Fisher, and P. M. Rose. 1993. Endothelin receptor B expression in the rat and rabbit lung as determined by in situ hybridization using nonisotopic probes. J. Cardiovasc. Pharmacol. 22(Suppl. 8):S1-S3.
10. B receptor. Am. J. Physiol. 264:R777-R783.
11. Goldie, R. G., A. C. D'Aprile, G. J. Self, P. J. Rigby, and P. J. Henry. 1996. The distribution and density of receptor subtypes for endothelin-1 in peripheral lung of rat, guinea-pig and pig. Br. J. Pharmacol. 117:729-735.
12. Li, H., T. S. Elton, Y. F. Chen, and S. Oparil. 1994. Increased endothelin receptor gene expression in hypoxic rat lung. Am. J. Physiol. 266:L553-L560.
13. Li, H., S. J. Chen, Y. F. Chen, Q. Cheng, J. Durand, S. Oparil, and T. S. Elton. 1994. Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia. J. Appl. Physiol. 77:1452-1459.
14. Gosselin, R., J. Gutkowska, J. Baribeau, and T. Perreault. 1997. Endothelin receptor changes in hypoxia-induced pulmonary hypertension in the newborn piglet. Am. J. Physiol. 273:L72-L79.
15. Fulton, R. M., E. C. Hucthinson, and A. M. Jones. 1952. Ventricular weight in cardiac hypertrophy. Br. Heart J. 14:413-420.
16. Sasaki, S. L, N. Kobayashi, T. Dambara, S. Kira, and T. Sakai. 1995. Structural organization of pulmonary arteries in the rat lung. Anat. Embryol. 191:477-489.
17. Hislop, A., and L. Reid. 1978. Normal structure and dimensions of the pulmonary arteries in the rat. J. Anat. 125:71-83.
18. Arai, H., S. Hori, I. Aramori, H. Ohkubo, and S. Nakanishi. 1990. Cloning and expression of cDNA encoding an endothelin receptor. Nature 348:730-732.
19. Sakurai, T., M. Yanagisawa, Y. Takuwa, H. Miyazaki, S. Kimura, G. Katsuloshi, and T. Masaki. 1990. Cloning of a cDNA encoding a non-isopeptide-selectivc subtype of the endothelin receptor. Nature 348:732-735.
20. Takahashi, H., K. Ishodo, D. Muno, A. Ohwada, T. Nukiwa, E. Kominami, and S. Kira. 1993. Cathepsin L activity is increased in alveolar macrophages and bronchoalveolar lavage fluid of smokers. Am. Rev. Respir. Dis. 147: 1562-1568.
21. Hislop, A., and L. Reid. 1976. New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. Br. J. Exp. Pathol. 57:542-554.
22. A receptor antagonist, attenuates endothelin-1-induced vasoconstriction in rat pulmonary circulation. J. Cardiovasc. Pharmacol. 22:39-43.
23. B-receptor-mediated vasoconstriction in rat pulmonary arteries and arterioles. J. Cardiovasc. Pharmacol. 23:838-845.
24. MacLean, M. R., K. M. McCullock, and M. Baird. 1995. Effects of pulmonary hypertension on vasoconstrictor responses to endothelin-1 and sarafotoxin S6C and on inherent tone in rat pulmonary arteries. J. Cardiovasc. Pharmacol. 26:822-830.
25. Hasunuma, K., D. M. Rodman, R. F. O'Brien, and I. F. McMurtry. 1990. Endothelin 1 causes pulmonary vasodilation in rats. Am. J. Physiol. 259: H48-H54.
26. Lippton, H. L., G. A. Cohen, I. F. McMurtry, and A. L. Hyman. 1991. Pulmonary vasodilation to endothelin isopeptides in vivo is mediated by potassium channel. J. Appl. Physiol. 70:947-952.
27. Wong, J., P. A. Vanderford, J. Winters, S. J. Soifer, and J. R. Fineman. 1995. Endothelin receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension. J. Cardiovasc. Pharmacol. 25:207-215.
28. Rodman, D. M., T. J. Stelzner, M. R. Zamora, S. T. Bonvallet, M. Oka, K. Sato, R. F. O'Brien, and I. F. McMurtry. 1992. Endothelin-1 increases the pulmonary microvascular pressure and causes pulmonary edema in salt solution but not blood perfused rat lungs. J. Cardiovasc. Pharmacol. 20:658-663.
29. Fukuroda, T., T. Fujikawa, S. Ozaki, K. Ishikawa, M. Yano, and M. Nishikibe. 1994. Clearance of circulating endothelin-1 by ETB receptors in rats. Biochem. Biophys. Res. Commun. 199:1461-1465.
30. B blockade on ET-1-induced constriction in perfused rat lungs. Am. J. Physiol. 269:L668-L672.
31. A-receptor antagonist, attenuates hypoxic pulmonary hypertension in rats. Am. J. Physiol. 266:H1327-H1331.
32. A-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in rat. Am. J. Physiol. 269:L690-L697.
33. Resta, T. C, and B. R. Walker. 1996. Chronic hypoxia selectively augments endothelium-dependent pulmonary arterial vasodilation. Am. J. Physiol. 270:H888-H896.
34. Mallat, A., L. Fouassier, A. M. Preaux, C. S. Gal, D. Raufaste, J. Rosenbaum, D. Dhumeaux, C. Jouneaux, P. Mavier, and S. Lotersztajn. 1995. Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. J. Clin. Invest. 96:42-49.
35. Eddahibi, S., B. Raffestin, M. Clozel, M. Levame, and S. Adnot. 1995. Protection from pulmonary hypertension with an orally active endothelin receptor antagonist in hypoxic rats. Am. J Physiol. 268:H828-H835.
36. Muramatsu, M., D. M. Rodman, M. Oka, and I. F. McMurtry. 1997. Endothelin-1 mediates nitro-L-arginine vasoconstriction of hypertensive rat lungs. Am. J. Physiol. 272:L807-L812.