KCNQ modulators reveal a key role for KCNQ potassium channels in regulating the tone of rat pulmonary artery smooth muscle

Journal of Pharmacology and Experimental Therapeutics

Volumn 329, Issue 1, 2009, Pages 368-376

  Joshi, Shreena ^a   Sedivy, Vojtech ^b   Hodyc, Daniel ^b   Herget, Jan ^b   Gurney, Alison M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

10,10 BIS(4 PYRIDINYLMETHYL) 9(10H) ANTHRACENONE; FLUPIRTINE; LINOPIRDINE; POTASSIUM CHANNEL KCNQ1; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCNQ3; POTASSIUM CHANNEL KCNQ4; POTASSIUM CHANNEL KCNQ5; RETIGABINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DRUG EFFECT; LUNG ARTERY PRESSURE; LUNG VASOCONSTRICTION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY ARTERY; RAT; SMOOTH MUSCLE FIBER MEMBRANE POTENTIAL; SMOOTH MUSCLE TONE;

ANIMALS; CELL MEMBRANE; ELECTROPHYSIOLOGY; HEMODYNAMICS; KCNQ POTASSIUM CHANNELS; LUNG; MALE; MEMBRANE POTENTIALS; MUSCLE TONUS; MUSCLE, SMOOTH, VASCULAR; MYOGRAPHY; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; PULMONARY ARTERY; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASODILATION;

EID: 63849294626     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.147785     Document Type: Article

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