-
1
-
-
0036682273
-
Inhaled iloprost for severe pulmonary hypertension
-
DOI 10.1056/NEJMoa020204
-
Olschewski H, Simonneau G, Galie N, Higenbottam T, Naeije R, Rubin LJ, Nikkho S, Speich R, Hoeper MM, Behr J, et al. Inhaled iloprost for severe pulmonary hypertension. N Engl J Med 2002;347:322-329. (Pubitemid 34815354)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.5
, pp. 322-329
-
-
Olschewski, H.1
Simonneau, G.2
Galie, N.3
Higenbottam, T.4
Naeije, R.5
Rubin, L.J.6
Nikkho, S.7
Speich, R.8
Hoeper, M.M.9
Behr, J.10
Winkler, J.11
Sitbon, O.12
Popov, W.13
Ardeschir, G.H.14
Manes, A.15
Kiely, D.G.16
Ewert, R.17
Meyer, A.18
Corris, P.A.19
Delcroix, M.20
Gomez-Sanchez, M.21
Siedentop, H.22
Seeger, W.23
more..
-
2
-
-
42949166212
-
Prostacyclin therapies for the treatment of pulmonary arterial hypertension
-
Gomberg-Maitland M, Olschewski H. Prostacyclin therapies for the treatment of pulmonary arterial hypertension. Eur Respir J 2008;31:891-901.
-
(2008)
Eur Respir J
, vol.31
, pp. 891-901
-
-
Gomberg-Maitland, M.1
Olschewski, H.2
-
3
-
-
78649721519
-
Treprostinil inhibits the recruitment of bone marrow derived circulating fibrocytes in chronic hypoxic pulmonary hypertension
-
Nikam VS, Schermuly RT, Dumitrascu R, Weissmann N, Kwapiszewska G, Morrell N, Klepetko W, Fink L, Seeger W, Voswinckel R. Treprostinil inhibits the recruitment of bone marrow derived circulating fibrocytes in chronic hypoxic pulmonary hypertension. Eur Respir J 2010;36:1302-1314.
-
(2010)
Eur Respir J
, vol.36
, pp. 1302-1314
-
-
Nikam, V.S.1
Schermuly, R.T.2
Dumitrascu, R.3
Weissmann, N.4
Kwapiszewska, G.5
Morrell, N.6
Klepetko, W.7
Fink, L.8
Seeger, W.9
Voswinckel, R.10
-
4
-
-
3242786247
-
Prostacyclin release and receptor activation: Differential control of human pulmonary venous and arterial tone
-
DOI 10.1038/sj.bjp.0705843
-
Norel X, Walch L, Gascard JP, deMontpreville V, Brink C. Prostacyclin release and receptor activation: differential control of human pulmonary venous and arterial tone. Br J Pharmacol 2004;142:788-796. (Pubitemid 38969674)
-
(2004)
British Journal of Pharmacology
, vol.142
, Issue.4
, pp. 788-796
-
-
Norel, X.1
Walch, L.2
Gascard, J.-P.3
De Montpreville, V.4
Brink, C.5
-
5
-
-
0029108913
-
Physiological roles and properties of potassium channels in arterial smooth muscle
-
Nelson MT, Quayle JM. Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 1995;268:C799-C822.
-
(1995)
Am J Physiol
, vol.268
-
-
Nelson, M.T.1
Quayle, J.M.2
-
6
-
-
0036119950
-
Potassium channels underlying the resting potential of pulmonary artery smooth muscle cells
-
DOI 10.1046/j.1440-1681.2002.03653.x
-
Gurney AM, Osipenko ON, MacMillan D, Kempsill FE. Potassium channels underlying the resting potential of pulmonary artery smooth muscle cells. Clin Exp Pharmacol Physiol 2002;29:330-333. (Pubitemid 34227069)
-
(2002)
Clinical and Experimental Pharmacology and Physiology
, vol.29
, Issue.4
, pp. 330-333
-
-
Gurney, A.M.1
Osipenko, O.N.2
MacMillan, D.3
Kempsill, F.E.J.4
-
7
-
-
33646816053
-
Impact of TASK-1 in human pulmonary artery smooth muscle cells
-
Olschewski A, Li Y, Tang B, Hanze J, Eul B, Bohle RM, Wilhelm J, Morty RE, Brau ME, Weir EK, et al. Impact of TASK-1 in human pulmonary artery smooth muscle cells. Circ Res 2006;98:1072-1080.
-
(2006)
Circ Res
, vol.98
, pp. 1072-1080
-
-
Olschewski, A.1
Li, Y.2
Tang, B.3
Hanze, J.4
Eul, B.5
Bohle, R.M.6
Wilhelm, J.7
Morty, R.E.8
Brau, M.E.9
Weir, E.K.10
-
8
-
-
0036716140
-
Minireview: A novel pathway of prostacyclin signaling - Hanging out with nuclear receptors
-
DOI 10.1210/en.2002-220159
-
Lim H, Dey SK. A novel pathway of prostacyclin signaling: hanging out with nuclear receptors. Endocrinology 2002;143:3207-3210. (Pubitemid 34925693)
-
(2002)
Endocrinology
, vol.143
, Issue.9
, pp. 3207-3210
-
-
Hyunjung, L.1
Dey, S.K.2
-
9
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne B, Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 1999;20:649-688. (Pubitemid 30650602)
-
(1999)
Endocrine Reviews
, vol.20
, Issue.5
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
11
-
-
65549087101
-
Antiplatelet actions of statins and fibrates are mediated by PPARs
-
Ali FY, Armstrong PC, Dhanji AR, Tucker AT, Paul-Clark MJ, Mitchell JA, Warner TD. Antiplatelet actions of statins and fibrates are mediated by PPARs. Arterioscler Thromb Vasc Biol 2009;29:706-711.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 706-711
-
-
Ali, F.Y.1
Armstrong, P.C.2
Dhanji, A.R.3
Tucker, A.T.4
Paul-Clark, M.J.5
Mitchell, J.A.6
Warner, T.D.7
-
12
-
-
32044471323
-
Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts
-
DOI 10.1165/rcmb.2005-0289OC
-
Ali FY, Egan K, FitzGerald GA, Desvergne B, Wahli W, Bishop-Bailey D, Warner TD, Mitchell JA. Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts. Am J Respir Cell Mol Biol 2006;34:242-246. (Pubitemid 43202472)
-
(2006)
American Journal of Respiratory Cell and Molecular Biology
, vol.34
, Issue.2
, pp. 242-246
-
-
Ali, F.Y.1
Egan, K.2
FitzGerald, G.A.3
Desvergne, B.4
Wahli, W.5
Bishop-Balley, D.6
Warner, T.D.7
Mitchell, J.A.8
-
13
-
-
33644883024
-
Role of nuclear receptor signaling in platelets: Antithrombotic effects of PPARbeta
-
DOI 10.1096/fj.05-4395fje
-
Ali FY, Davidson SJ, Moraes LA, Traves SL, Paul-Clark M, Bishop-Bailey D, Warner TD, Mitchell JA. Role of nuclear receptor signaling in platelets: antithrombotic effects of PPARbeta. FASEB J 2006;20:326-328. (Pubitemid 46671159)
-
(2006)
FASEB Journal
, vol.20
, Issue.2
, pp. 326-328
-
-
Ali, F.Y.1
Davidson, S.J.2
Moraes, L.A.3
Traves, S.L.4
Paul-Clark, M.5
Bishop-Bailey, D.6
Warner, T.D.7
Mitchell, J.A.8
-
14
-
-
77949663350
-
The PPARbeta/delta agonist GW0742 relaxespulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension
-
Harrington LS, Moreno L, Reed A, Wort SJ, Desvergne B, Garland C, Zhao L, Mitchell JA. The PPARbeta/delta agonist GW0742 relaxespulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension. PLoS ONE 2010;5:e9526.
-
(2010)
PLoS ONE
, vol.5
-
-
Harrington, L.S.1
Moreno, L.2
Reed, A.3
Wort, S.J.4
Desvergne, B.5
Garland, C.6
Zhao, L.7
Mitchell, J.A.8
-
16
-
-
75749129360
-
Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C
-
Auer-Grumbach M, Olschewski A, Papic L, Kremer H, McEntagart ME, Uhrig S, Fischer C, Frohlich E, Balint Z, Tang B, et al. Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C. Nat Genet 2010;42:160-164.
-
(2010)
Nat Genet
, vol.42
, pp. 160-164
-
-
Auer-Grumbach, M.1
Olschewski, A.2
Papic, L.3
Kremer, H.4
McEntagart, M.E.5
Uhrig, S.6
Fischer, C.7
Frohlich, E.8
Balint, Z.9
Tang, B.10
-
17
-
-
70349084966
-
Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells
-
Tang B, Li Y, Nagaraj C, Morty RE, Gabor S, Stacher E, Voswinckel R, Weissmann N, Leithner K, Olschewski H, et al. Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol 2009;41:476-483.
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 476-483
-
-
Tang, B.1
Li, Y.2
Nagaraj, C.3
Morty, R.E.4
Gabor, S.5
Stacher, E.6
Voswinckel, R.7
Weissmann, N.8
Leithner, K.9
Olschewski, H.10
-
18
-
-
0026628265
-
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension
-
Christman BW, McPherson CD, Newman JH, King GA, Bernard GR, Groves BM, Loyd JE. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Engl J Med 1992;327:70-75.
-
(1992)
N Engl J Med
, vol.327
, pp. 70-75
-
-
Christman, B.W.1
McPherson, C.D.2
Newman, J.H.3
King, G.A.4
Bernard, G.R.5
Groves, B.M.6
Loyd, J.E.7
-
19
-
-
0031697797
-
Lipid mediator dysregulation in primary pulmonary hypertension
-
Christman BW. Lipid mediator dysregulation in primary pulmonary hypertension. Chest 1998;114:205S-207S. (Pubitemid 28435969)
-
(1998)
Chest
, vol.114
, Issue.3 SUPPL.
-
-
Christman, B.W.1
-
20
-
-
0033032949
-
Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension
-
Tuder RM, Cool CD, Geraci MW, Wang J, Abman SH, Wright L, Badesch D, Voelkel NF. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension. Am J Respir Crit Care Med 1999;159:1925-1932. (Pubitemid 29275065)
-
(1999)
American Journal of Respiratory and Critical Care Medicine
, vol.159
, Issue.6
, pp. 1925-1932
-
-
Tuder, R.M.1
Cool, C.D.2
Geraci, M.W.3
Wang, J.4
Abman, S.H.5
Wright, L.6
Badesch, D.7
Voelkel, N.F.8
-
21
-
-
70349634397
-
Guidelines for the diagnosis and treatment of pulmonary hypertension
-
Galie N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, Beghetti M, Corris P, Gaine S, Gibbs JS, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J 2009;34:1219-1263.
-
(2009)
Eur Respir J
, vol.34
, pp. 1219-1263
-
-
Galie, N.1
Hoeper, M.M.2
Humbert, M.3
Torbicki, A.4
Vachiery, J.L.5
Barbera, J.A.6
Beghetti, M.7
Corris, P.8
Gaine, S.9
Gibbs, J.S.10
-
22
-
-
33646590328
-
Ca channel alpha- and beta-subunits
-
DOI 10.1152/ajplung.00283.2005
-
Resnik E, Herron J, Fu R, Ivy DD, Cornfield DN. Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta-subunits. Am J Physiol Lung Cell Mol Physiol 2006;290:L761-L768. (Pubitemid 43725082)
-
(2006)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.290
, Issue.4
-
-
Resnik, E.1
Herron, J.2
Fu, R.3
Ivy, D.D.4
Cornfield, D.N.5
-
23
-
-
55249099291
-
Expression of BK(Ca) channels in human pulmonary arteries: Relationship with remodeling and hypoxic pulmonary vasoconstriction
-
Peinado VI, Paris R, Ramirez J, Roca J, Rodriguez-Roisin R, Barbera JA. Expression of BK(Ca) channels in human pulmonary arteries: relationship with remodeling and hypoxic pulmonary vasoconstriction. Vascul Pharmacol 2008;49:178-184.
-
(2008)
Vascul Pharmacol
, vol.49
, pp. 178-184
-
-
Peinado, V.I.1
Paris, R.2
Ramirez, J.3
Roca, J.4
Rodriguez-Roisin, R.5
Barbera, J.A.6
-
24
-
-
0032934180
-
Prostanoid receptors involved in the relaxation of human pulmonary vessels
-
Walch L, Labat C, Gascard JP, de Montpreville V, Brink C, Norel X. Prostanoid receptors involved in the relaxation of human pulmonary vessels. Br J Pharmacol 1999;126:859-866. (Pubitemid 29103701)
-
(1999)
British Journal of Pharmacology
, vol.126
, Issue.4
, pp. 859-866
-
-
Walch, L.1
Labat, C.2
Gascard, J.-P.3
De Montpreville, V.4
Brink, C.5
Norel, X.6
-
25
-
-
32244442817
-
RO1138452 and RO3244794: Characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists
-
DOI 10.1038/sj.bjp.0706554, PII 0706554
-
Bley KR, Bhattacharya A, Daniels DV, Gever J, Jahangir A, O'Yang C, Smith S, Srinivasan D, Ford AP, Jett MF. RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists. Br J Pharmacol 2006;147:335-345. (Pubitemid 43214691)
-
(2006)
British Journal of Pharmacology
, vol.147
, Issue.3
, pp. 335-345
-
-
Bley, K.R.1
Bhattacharya, A.2
Daniels, D.V.3
Gever, J.4
Jahangir, A.5
O'Yang, C.6
Smith, S.7
Srinivasan, D.8
Ford, A.P.D.W.9
Jett, M.-F.10
-
26
-
-
38749152401
-
Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist
-
DOI 10.1210/me.2007-0190
-
Shearer BG, Steger DJ, Way JM, Stanley TB, Lobe DC, Grillot DA, Iannone MA, Lazar MA, Willson TM, Billin AN. Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist. Mol Endocrinol 2008;22:523-529. (Pubitemid 351185947)
-
(2008)
Molecular Endocrinology
, vol.22
, Issue.2
, pp. 523-529
-
-
Shearer, B.G.1
Steger, D.J.2
Way, J.M.3
Stanley, T.B.4
Lobe, D.C.5
Grillot, D.A.6
Iannone, M.A.7
Lazar, M.A.8
Willson, T.M.9
Billin, A.N.10
|