Changes in α1-adrenergic vascular reactivity in monocrotaline-treated rats

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 365, Issue 2, 2002, Pages 87-95

  Dhein, Stefan ^a   Giessler, Christine ^a   Heinroth Hoffmann, Ingrid ^a   Leineweber, Kirsten ^a   Seyfarth, Torsten ^a   Brodde, Otto Erich ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Alpha adrenoceptors; Endothelium; Monocrotaline; Pulmonary hypertension; Rat

Indexed keywords

5 METHYLURAPIDIL; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; CARBACHOL; CHLOROETHYLCLONIDINE; MONOCROTALINE; NORADRENALIN; RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY OCCLUSION; ARTICLE; BLOOD VESSEL REACTIVITY; CALCULATION; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SELECTIVITY; ENDOTHELIUM INJURY; HEART RIGHT VENTRICLE FAILURE; HEART RIGHT VENTRICLE PRESSURE; LUNG INFILTRATE; MALE; MESENTERIC ARTERY; NONHUMAN; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; THORACIC AORTA;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CLONIDINE; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MESENTERIC ARTERIES; MONOCROTALINE; NOREPINEPHRINE; PIPERAZINES; PULMONARY ARTERY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; THORACIC ARTERIES; VASOCONSTRICTION;

EID: 0036210437     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-001-0515-9     Document Type: Article

References (42)

1. Altered pulmonary vascular smooth muscle responsiveness in monocrotaline-induced pulmonary hypertension
2. Cardiac and vascular responses after monocrotaline-induced hypertrophy in rats
3. Aorta and skeletal muscle NO synthase expression in experimental heart failure
4. q/11-coupled receptor stimulation
5. Rat models of hypertension, cardiac hypertrophy and failure
6. 1-adrenoceptors mediating contractions of rabbit isolated ear artery: Comparison with rat isolated thoracic aorta
7. Vascular hyperresponsiveness in perfused lungs from monocrotaline-treated rats
8. 1-adrenoceptors
9. 5-Methylurapidil discriminates between subtypes of the α1-adrenoceptor
10. Vascular adrenoceptors: An update
11. Subclassification of α1-adrenoceptor recognition sites by urapidil derivatives and other selective antagonists
12. Increased vascular responsiveness in lungs of rats with pulmonary hypertension induced by monocrotaline pyrrol
13. Characterization of alpha1-adrenoceptor subtypes mediating contraction to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery
14. Biventricular down-regulation of beta-adrenergic receptors in right ventricular hypertrophy induced by monocrotaline
15. Alterations of endothelium and smooth muscle function in monocrotaline-induced pulmonary hypertensive arteries
16. Role of 5-hydroxytryptamine in the progression of monocrotaline-induced pulmonary hypertension in rats
17. Pulmonary hypertension in rats produced by the ingestion of Crotolaria spectabilis seeds
18. Altered artery mechanics and structure in monocrotaline pulmonary hypertension
19. 1) in right ventricles of monocrotaline-treated rats
20. An electron microscopic study of pulmonary vasculitis induced by monocrotaline
21. 2-adrenoceptor subtypes
22. Classification of α1-adrenoceptor subtypes
23. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats
24. Red blood cells augment transport of reactive metabolites of monocrotaline from liver to lung in isolated and tandem liver and lung preparations
25. Endothelial injury and vascular reactivity in monocrotaline pulmonary hypertension
26. The cardiac β-adrenoceptor-G-protein(s)-adenylyl cyclase system in monocrotaline-treated rats
27. +-adenosine trisphosphatase activity of pulmonary arteries after intoxication with the pyrrolizine alkaloid, monocrotaline
28. 1L-adrenoceptor pharmacology in rat small mesenteric artery
29. 1B-adrenoceptor subtype
30. Variable expression of endothelial NP synthase in three forms of rat pulmonary hypertension
31. Alterations in pulmonary alveoli after a single injection of monocrotaline
32. Isoproterenol sensitivity of isolated cardiac myocytes from rats with monocrotaline-induced right-sided hypertrophy and heart failure
33. 1A subtypes
34. Primary pulmonary hypertension
35. Endothelin and 5-hydroxytryptamine on rat pulmonary artery in pulmonary hypertension
36. Increased relaxation by felodipine on pulmonary artery from rats with monocrotaline-induced pulmonary hypertension does not reflect functional impairment of the endothelium
37. Diagnosis and management of primary pulmonary hypertension
38. Progressive inflammatory and structural changes in the pulmonary vasculature of monocrotaline-treated rats
39. Quantification of mRNAs for three α1-adrenoceptor subtypes in rat aorta by solution hybridisation
40. The relationship between the concentration of the pyrrolizidine alkaloid moncrotaline and the pattern of metabolites released from the isolated liver
41. 1D-adrenoceptor protein detectable in rat tissues?
42. 1-adrenoceptors