메뉴 건너뛰기




Volumn 24, Issue 4, 2004, Pages 615-623

Brief adrenomedullin inhalation leads to sustained reduction of pulmonary artery pressure

Author keywords

Acute respiratory distress syndrome; Adrenomedullin; Aerosol; Endothelin 1; Pulmonary hypertension

Indexed keywords

ADRENOMEDULLIN; CYCLIC AMP; ENDOTHELIN 1; MESSENGER RNA; SODIUM CHLORIDE; VASODILATOR AGENT;

EID: 6444241135     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.04.00016103     Document Type: Article
Times cited : (19)

References (28)
  • 1
    • 0033694964 scopus 로고    scopus 로고
    • The role of endogenous lung neuropeptides in regulation of the pulmonary circulation
    • Keith IM. The role of endogenous lung neuropeptides in regulation of the pulmonary circulation. Physiol Res 2000; 49: 519-537.
    • (2000) Physiol. Res. , vol.49 , pp. 519-537
    • Keith, I.M.1
  • 2
    • 0027324745 scopus 로고
    • Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
    • Giaid A, Yanagisawa M, Langleben D, et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med 1993; 328: 1732-1739.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1732-1739
    • Giaid, A.1    Yanagisawa, M.2    Langleben, D.3
  • 3
    • 0028954392 scopus 로고
    • Interleukin-1, tumour necrosis factor and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells
    • Sugo S, Minamino N, Shoji H, et al. Interleukin-1, tumour necrosis factor and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells. Biochem Biophys Res Commun 1995; 207: 25-32.
    • (1995) Biochem. Biophys. Res. Commun. , vol.207 , pp. 25-32
    • Sugo, S.1    Minamino, N.2    Shoji, H.3
  • 4
    • 0034674021 scopus 로고    scopus 로고
    • Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature
    • Shindo T, Kurihara H, Maemura K, et al. Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature. Circulation 2000; 101: 2309-2316.
    • (2000) Circulation , vol.101 , pp. 2309-2316
    • Shindo, T.1    Kurihara, H.2    Maemura, K.3
  • 5
    • 0035688596 scopus 로고    scopus 로고
    • Human adrenomedullin gene delivery protects against cardiovascular remodeling and renal injury
    • Chao J, Kato K, Zhang JJ, et al. Human adrenomedullin gene delivery protects against cardiovascular remodeling and renal injury. Peptides 2001; 22: 1731-1737.
    • (2001) Peptides , vol.22 , pp. 1731-1737
    • Chao, J.1    Kato, K.2    Zhang, J.J.3
  • 6
    • 0035895276 scopus 로고    scopus 로고
    • Extreme hydrops foetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
    • Caron KM, Smithies O. Extreme hydrops foetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proc Natl Acad Sci USA 2001; 98: 615-619.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 615-619
    • Caron, K.M.1    Smithies, O.2
  • 7
    • 0035899895 scopus 로고    scopus 로고
    • Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene
    • Shindo T, Kurihara Y, Nishimatsu H, et al. Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene. Circulation 2001; 104: 1964-1971.
    • (2001) Circulation , vol.104 , pp. 1964-1971
    • Shindo, T.1    Kurihara, Y.2    Nishimatsu, H.3
  • 8
    • 0036140729 scopus 로고    scopus 로고
    • Adrenomedullin, an endogenous peptide, counteracts cardiovascular damage
    • Shimosawa T, Shibagaki Y, Ishibashi K, et al. Adrenomedullin, an endogenous peptide, counteracts cardiovascular damage. Circulation 2002; 105: 106-111.
    • (2002) Circulation , vol.105 , pp. 106-111
    • Shimosawa, T.1    Shibagaki, Y.2    Ishibashi, K.3
  • 9
    • 0033659044 scopus 로고    scopus 로고
    • Haemodynamic and hormonal effects of adrenomedullin in patients with pulmonary hypertension
    • Nagaya N, Nishikimi T, Uematsu M, et al. Haemodynamic and hormonal effects of adrenomedullin in patients with pulmonary hypertension. Heart 2000; 84: 653-658.
    • (2000) Heart , vol.84 , pp. 653-658
    • Nagaya, N.1    Nishikimi, T.2    Uematsu, M.3
  • 11
    • 0041430870 scopus 로고    scopus 로고
    • Pilot intervention: Aerosolized adrenomedullin reduces pulmonary hypertension
    • Kandler MA, von der Hardt K, Mahfoud S, et al. Pilot intervention: aerosolized adrenomedullin reduces pulmonary hypertension. J Pharmacol Exp Ther 2003; 306: 1021-1026.
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 1021-1026
    • Kandler, M.A.1    von der Hardt, K.2    Mahfoud, S.3
  • 12
    • 0037073597 scopus 로고    scopus 로고
    • Aerosolized adrenomedullin suppresses pulmonary transforming growth factor-beta1 and interleukin-1 beta gene expression in vivo
    • von der Hardt K, Kandler MA, Popp K, et al. Aerosolized adrenomedullin suppresses pulmonary transforming growth factor-beta1 and interleukin-1 beta gene expression in vivo. Eur J Pharmacol 2002; 457: 71-76.
    • (2002) Eur. J. Pharmacol. , vol.457 , pp. 71-76
    • von der Hardt, K.1    Kandler, M.A.2    Popp, K.3
  • 13
    • 0028233752 scopus 로고
    • Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells
    • Ishizaka Y, Ishizaka Y, Tanaka M, et al. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem Biophys Res Commun 1994; 200: 642-646.
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , pp. 642-646
    • Ishizaka, Y.1    Ishizaka, Y.2    Tanaka, M.3
  • 14
    • 0028922340 scopus 로고
    • Adrenomedullin stimulates two signal transduction pathways, cAMP accumulation and Ca2+ mobilization, in bovine aortic endothelial cells
    • Shimekake Y, Nagata K, Ohta S, et al. Adrenomedullin stimulates two signal transduction pathways, cAMP accumulation and Ca2+ mobilization, in bovine aortic endothelial cells. J Biol Chem 1995; 270: 4412-4417.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4412-4417
    • Shimekake, Y.1    Nagata, K.2    Ohta, S.3
  • 15
    • 0025644508 scopus 로고
    • Nitroprusside enhances isoprenaline-induced increases in cAMP in rat aortic smooth muscle
    • Maurice DH, Haslam RJ. Nitroprusside enhances isoprenaline-induced increases in cAMP in rat aortic smooth muscle. Eur J Pharmacol 1990; 191: 471-475.
    • (1990) Eur. J. Pharmacol. , vol.191 , pp. 471-475
    • Maurice, D.H.1    Haslam, R.J.2
  • 16
    • 0028149065 scopus 로고
    • Endothelin secretion is regulated by cyclic AMP and phosphatase 2A in endothelial cells
    • Magnusson A, Halldorsson H, Thorgeirsson G, Kjeld M. Endothelin secretion is regulated by cyclic AMP and phosphatase 2A in endothelial cells. J Cell Physiol 1994; 161: 429-434.
    • (1994) J. Cell Physiol. , vol.161 , pp. 429-434
    • Magnusson, A.1    Halldorsson, H.2    Thorgeirsson, G.3    Kjeld, M.4
  • 18
    • 0033308651 scopus 로고    scopus 로고
    • Leptin and neuropeptide Y gene expression in human placenta: Ontogeny and evidence for similarities to hypothalamic regulation
    • Dötsch J, Nusken KD, Knerr I, Kirschbaum M, Repp R, Rascher W. Leptin and neuropeptide Y gene expression in human placenta: ontogeny and evidence for similarities to hypothalamic regulation. J Clin Endocrinol Metab 1999; 84: 2755-2758.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 2755-2758
    • Dötsch, J.1    Nusken, K.D.2    Knerr, I.3    Kirschbaum, M.4    Repp, R.5    Rascher, W.6
  • 19
    • 0032990183 scopus 로고    scopus 로고
    • Respiratory and haemodynamic effects of the prone position at two different levels of PEEP in a canine acute lung injury model
    • Lim CM, Koh Y, Chin JY, et al. Respiratory and haemodynamic effects of the prone position at two different levels of PEEP in a canine acute lung injury model. Eur Respir J 1999; 13: 163-168.
    • (1999) Eur. Respir. J. , vol.13 , pp. 163-168
    • Lim, C.M.1    Koh, Y.2    Chin, J.Y.3
  • 20
    • 0036796403 scopus 로고    scopus 로고
    • Prone position in acute respiratory distress syndrome
    • Pelosi P, Brazzi L, Gattinoni L. Prone position in acute respiratory distress syndrome. Eur Respir J 2002; 20: 1017-1028.
    • (2002) Eur. Respir. J. , vol.20 , pp. 1017-1028
    • Pelosi, P.1    Brazzi, L.2    Gattinoni, L.3
  • 22
    • 0029850521 scopus 로고    scopus 로고
    • Inhaled nitric oxide in neonatal and paediatric acute respiratory distress syndrome: Dose response, prolonged inhalation, and weaning
    • Demirakca S, Dotsch J, Knothe C, et al. Inhaled nitric oxide in neonatal and paediatric acute respiratory distress syndrome: dose response, prolonged inhalation, and weaning. Crit Care Med 1996; 24: 1913-1919.
    • (1996) Crit. Care Med. , vol.24 , pp. 1913-1919
    • Demirakca, S.1    Dotsch, J.2    Knothe, C.3
  • 23
    • 0034696634 scopus 로고    scopus 로고
    • Inhaled iloprost to treat severe pulmonary hypertension. An uncontrolled trial
    • German PPH Study Group
    • Olschewski H, Ghofrani HA, Schmehl T, et al. Inhaled iloprost to treat severe pulmonary hypertension. An uncontrolled trial. German PPH Study Group. Ann Intern Med 2000; 132: 435-443.
    • (2000) Ann. Intern. Med. , vol.132 , pp. 435-443
    • Olschewski, H.1    Ghofrani, H.A.2    Schmehl, T.3
  • 24
    • 0033215263 scopus 로고    scopus 로고
    • Adrenomedullin augments nitric oxide and tetrahydrobioptein synthesis in cytokine-stimulated vascular smooth muscle cells
    • Hattori Y, Nakanishi N, Gross SS, Kasai K. Adrenomedullin augments nitric oxide and tetrahydrobioptein synthesis in cytokine-stimulated vascular smooth muscle cells. Cardiovasc Res 1999; 44: 207-214.
    • (1999) Cardiovasc. Res. , vol.44 , pp. 207-214
    • Hattori, Y.1    Nakanishi, N.2    Gross, S.S.3    Kasai, K.4
  • 26
    • 6444219645 scopus 로고    scopus 로고
    • Aerosolized adrenomedullin improves pulmonary hypertension and oxygenation and reduces fibrotic response
    • von der Hardt K, Kandler MA, Schoof E, Dötsch J, Rascher W. Aerosolized adrenomedullin improves pulmonary hypertension and oxygenation and reduces fibrotic response. Eur J Pediatr 2002: 161.
    • (2002) Eur. J. Pediatr. , pp. 161
    • von der Hardt, K.1    Kandler, M.A.2    Schoof, E.3    Dötsch, J.4    Rascher, W.5
  • 27
    • 0028088778 scopus 로고
    • L-NAME modulates responses to adrenomedullin in the hindquarters vascular bed of the rat
    • Feng CJ, Kang B, Kaye AD, Kadowitz PJ, Nossaman BD. L-NAME modulates responses to adrenomedullin in the hindquarters vascular bed of the rat. Life Sci 1994; 55: 433-438.
    • (1994) Life Sci. , vol.55 , pp. 433-438
    • Feng, C.J.1    Kang, B.2    Kaye, A.D.3    Kadowitz, P.J.4    Nossaman, B.D.5
  • 28
    • 18444409941 scopus 로고    scopus 로고
    • Genomic organization and regulation of a human 7-helix transmembrane receptor which is expressed in pulmonary epithelial cells and induced in hypoxia
    • Hänze J, Groneberg DA, Rose F, et al. Genomic organization and regulation of a human 7-helix transmembrane receptor which is expressed in pulmonary epithelial cells and induced in hypoxia. Biochem Biophys Res Commun 2002; 291: 1160-1165.
    • (2002) Biochem. Biophys. Res. Commun. , vol.291 , pp. 1160-1165
    • Hänze, J.1    Groneberg, D.A.2    Rose, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.