Preferential expression and function of voltage-gated, O 2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: Ionic diversity in smooth muscle cells

Circulation Research

Volumn 95, Issue 3, 2004, Pages 308-318

  Archer, Stephen L ^a   Wu, Xi Chen ^a   Thébaud, Bernard ^a   Nsair, Ali ^a   Bonnet, Sebastien ^a   Tyrrell, Ben ^a   McMurtry, M Sean ^a   Hashimoto, Kyoko ^a   Harry, Gwyneth ^a   Michelakis, Evangelos D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Adenoviral gene transfer; Immunoelectropharmacology; Laser capture microdissection; Pulmonary circulation; Voltage gated channels

Indexed keywords

4 AMINOPYRIDINE; ADENOVIRUS VECTOR; ANTIBODY; CORREOLIDE; IBERIOTOXIN; ION; MESSENGER RNA; OXYGEN; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT; TITYUS TOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ADOLESCENT; ANIMAL TISSUE; ARTERY DIAMETER; ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; EXTRAPULMONARY ARTERY; GENE TRANSFER; HYPERPOLARIZATION; HYPOXIC LUNG VASOCONSTRICTION; LASER CAPTURE MICRODISSECTION; LUNG ARTERY; LUNG CIRCULATION; MALE; MEMBRANE POTENTIAL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESISTANCE BLOOD VESSEL; SMOOTH MUSCLE FIBER; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VOLTAGE GATED OXYGEN SENSITIVE POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL SUBUNIT KV1.1B; VOLTAGE GATED POTASSIUM CHANNEL SUBUNIT KV1.2; VOLTAGE GATED POTASSIUM CHANNEL SUBUNIT KV1.5; VOLTAGE GATED POTASSIUM CHANNEL SUBUNIT KV2.1; VOLTAGE GATED POTASSIUM CHANNEL SUBUNIT KV4.3; VOLTAGE GATED POTASSIUM CHANNEL SUBUNIT KV9.3;

4-AMINOPYRIDINE; ACETYLCHOLINE; ANIMALS; ANOXIA; CELL HYPOXIA; CELLS, CULTURED; GENE EXPRESSION REGULATION; HUMANS; ION CHANNEL GATING; ION TRANSPORT; KV1.5 POTASSIUM CHANNEL; MALE; MEMBRANE POTENTIALS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXYGEN; PATCH-CLAMP TECHNIQUES; PEPTIDES; POTASSIUM; POTASSIUM CHANNELS, VOLTAGE-GATED; PULMONARY ARTERY; PULMONARY CIRCULATION; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; SCORPION VENOMS; SHAB POTASSIUM CHANNELS; TRANSDUCTION, GENETIC; TRITERPENES; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 4043123181     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000137173.42723.fb     Document Type: Article

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