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Volumn 21, Issue 3, 2014, Pages 259-271

Calcium homeostasis and sensitization in pulmonary arterial smooth muscle

Author keywords

Actin polymerization; Calcium entry; Calcium sensitization; Hypoxia; Pulmonary hypertension; Vascular smooth muscle

Indexed keywords

CALCIUM; CATION CHANNEL; PROTEIN KINASE C; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; VOLTAGE GATED CALCIUM CHANNEL; ACTIN; CALCIUM CHANNEL;

EID: 84898027147     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1111/micc.12096     Document Type: Article
Times cited : (41)

References (114)
  • 1
    • 84859607472 scopus 로고    scopus 로고
    • Targeting RhoA/ROCK pathway in pulmonary arterial hypertension
    • Antoniu S. Targeting RhoA/ROCK pathway in pulmonary arterial hypertension. Expert Opin Ther Targets 16: 355-363, 2012.
    • (2012) Expert Opin Ther Targets , vol.16 , pp. 355-363
    • Antoniu, S.1
  • 2
    • 74949129817 scopus 로고    scopus 로고
    • Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA
    • Broughton BRS, Jernigan NL, Norton CE, Walker BR, Resta TC. Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA. Am J Physiol Lung Cellular Mol Physiol 298: L232-L242, 2010.
    • (2010) Am J Physiol Lung Cellular Mol Physiol , vol.298
    • Broughton, B.R.S.1    Jernigan, N.L.2    Norton, C.E.3    Walker, B.R.4    Resta, T.C.5
  • 3
    • 42049083338 scopus 로고    scopus 로고
    • Chronic hypoxia induces Rho kinase-dependent myogenic tone in small pulmonary arteries
    • Broughton BRS, Walker BR, Resta TC. Chronic hypoxia induces Rho kinase-dependent myogenic tone in small pulmonary arteries. Am J Physiol Lung Cell Mol Physiol 294: L797-L806, 2008.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294
    • Broughton, B.R.S.1    Walker, B.R.2    Resta, T.C.3
  • 5
    • 0036135875 scopus 로고    scopus 로고
    • Pressure-induced actin polymerization in vascular smooth muscle as a mechanism underlying myogenic behavior
    • Cipolla MJ, Gokina NI, Osol G. Pressure-induced actin polymerization in vascular smooth muscle as a mechanism underlying myogenic behavior. FASEB J 16: 72-76, 2002.
    • (2002) FASEB J , vol.16 , pp. 72-76
    • Cipolla, M.J.1    Gokina, N.I.2    Osol, G.3
  • 6
    • 84884285662 scopus 로고    scopus 로고
    • Hypoxic pulmonary vasoconstriction in the absence of pretone: essential role for intracellular Ca2+ release
    • Connolly MJ, Prieto-Lloret J, Becker S, Ward JP, Aaronson P. Hypoxic pulmonary vasoconstriction in the absence of pretone: essential role for intracellular Ca2+ release. J Physiol 591(Pt 18): 4473-4498, 2013.
    • (2013) J Physiol , vol.591 , Issue.PART 18 , pp. 4473-4498
    • Connolly, M.J.1    Prieto-Lloret, J.2    Becker, S.3    Ward, J.P.4    Aaronson, P.5
  • 7
    • 84868350310 scopus 로고    scopus 로고
    • Implication of the ryanodine receptor in TRPV4-induced calcium response in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats
    • Dahan D, Ducret T, Quignard J-F, Marthan R, Savineau J-P, Estève E. Implication of the ryanodine receptor in TRPV4-induced calcium response in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats. Am J Physiol Lung Cellular Mol Physiol 303: L824-L833, 2012.
    • (2012) Am J Physiol Lung Cellular Mol Physiol , vol.303
    • Dahan, D.1    Ducret, T.2    Quignard, J.-F.3    Marthan, R.4    Savineau, J.-P.5    Estève, E.6
  • 8
    • 27544460168 scopus 로고    scopus 로고
    • Regulation of pulmonary arterial myosin phosphatase activity in neonatal circulatory transition and in hypoxic pulmonary hypertension: a role for CPI-17
    • Dakshinamurti S, Mellow L, Stephens NL. Regulation of pulmonary arterial myosin phosphatase activity in neonatal circulatory transition and in hypoxic pulmonary hypertension: a role for CPI-17. Pediatr Pulmonol 40: 398-407, 2005.
    • (2005) Pediatr Pulmonol , vol.40 , pp. 398-407
    • Dakshinamurti, S.1    Mellow, L.2    Stephens, N.L.3
  • 9
    • 77952492039 scopus 로고    scopus 로고
    • New therapies for pulmonary arterial hypertension: an update on current bench to bedside translation
    • Dewachter L, Dewachter C, Naeije R. New therapies for pulmonary arterial hypertension: an update on current bench to bedside translation. Expert Opin Investig Drugs 19: 469-488, 2010.
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 469-488
    • Dewachter, L.1    Dewachter, C.2    Naeije, R.3
  • 10
    • 30144440518 scopus 로고    scopus 로고
    • Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction
    • Du W, Frazier M, McMahon TJ, Eu JP. Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction. Chest 128: S556-S558, 2005.
    • (2005) Chest , vol.128
    • Du, W.1    Frazier, M.2    McMahon, T.J.3    Eu, J.P.4
  • 14
    • 0032887933 scopus 로고    scopus 로고
    • Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs
    • Fike CD, Kaplowitz MR. Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs. Am J Physiol Lung Cellular Mol Physiol 277: L449-L456, 1999.
    • (1999) Am J Physiol Lung Cellular Mol Physiol , vol.277
    • Fike, C.D.1    Kaplowitz, M.R.2
  • 15
    • 57049088175 scopus 로고    scopus 로고
    • Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension
    • Fike CD, Slaughter JC, Kaplowitz MR, Zhang Y, Aschner JL. Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cellular Mol Physiol 295: L881-L888, 2008.
    • (2008) Am J Physiol Lung Cellular Mol Physiol , vol.295
    • Fike, C.D.1    Slaughter, J.C.2    Kaplowitz, M.R.3    Zhang, Y.4    Aschner, J.L.5
  • 17
    • 0031956106 scopus 로고    scopus 로고
    • Hypoxic pulmonary endothelial cells release a diffusible contractile factor distinct from endothelin
    • Gaine SP, Hales MA, Flavahan NA. Hypoxic pulmonary endothelial cells release a diffusible contractile factor distinct from endothelin. Am J Physiol Lung Cellular Mol Physiol 274: L657-L664, 1998.
    • (1998) Am J Physiol Lung Cellular Mol Physiol , vol.274
    • Gaine, S.P.1    Hales, M.A.2    Flavahan, N.A.3
  • 18
    • 79958753913 scopus 로고    scopus 로고
    • The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ
    • Grassie ME, Moffat LD, Walsh MP, MacDonald JA. The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ. Arch Biochem Biophys 510: 147-159, 2011.
    • (2011) Arch Biochem Biophys , vol.510 , pp. 147-159
    • Grassie, M.E.1    Moffat, L.D.2    Walsh, M.P.3    MacDonald, J.A.4
  • 19
    • 53449100875 scopus 로고    scopus 로고
    • Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction
    • Gunst SJ, Zhang W. Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction. Am J Physiol Cell Physiol 295: C576-C587, 2008.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Gunst, S.J.1    Zhang, W.2
  • 20
    • 34250810128 scopus 로고    scopus 로고
    • Current topics in the regulatory mechanism underlying the Ca2+ sensitization of the contractile apparatus in vascular smooth muscle
    • Hirano K. Current topics in the regulatory mechanism underlying the Ca2+ sensitization of the contractile apparatus in vascular smooth muscle. J Pharmacol Sci 104: 109-115, 2007.
    • (2007) J Pharmacol Sci , vol.104 , pp. 109-115
    • Hirano, K.1
  • 22
    • 0037440743 scopus 로고    scopus 로고
    • Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation
    • Howell K, Preston RJ, McLoughlin P. Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation. J Physiol 547: 133-145, 2003.
    • (2003) J Physiol , vol.547 , pp. 133-145
    • Howell, K.1    Preston, R.J.2    McLoughlin, P.3
  • 23
    • 22744455284 scopus 로고    scopus 로고
    • Inhibition of Rho-Kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation
    • Hyvelin J-M, Howell K, Nichol A, Costello CM, Preston RJ, McLoughlin P. Inhibition of Rho-Kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation. Circ Res 97: 185-191, 2005.
    • (2005) Circ Res , vol.97 , pp. 185-191
    • Hyvelin, J.-M.1    Howell, K.2    Nichol, A.3    Costello, C.M.4    Preston, R.J.5    McLoughlin, P.6
  • 24
    • 0030870880 scopus 로고    scopus 로고
    • Prominent role of intracellular Ca2+ release in hypoxic vasoconstriction of canine pulmonary artery
    • Jabr RI, Toland H, Gelband CH, Xia Wang X, Hume JR. Prominent role of intracellular Ca2+ release in hypoxic vasoconstriction of canine pulmonary artery. Br J Pharmacol 122: 21-30, 1997.
    • (1997) Br J Pharmacol , vol.122 , pp. 21-30
    • Jabr, R.I.1    Toland, H.2    Gelband, C.H.3    Xia Wang, X.4    Hume, J.R.5
  • 25
    • 0034995874 scopus 로고    scopus 로고
    • Heterogeneity of calcium stores and elementary release events in canine pulmonary arterial smooth muscle cells
    • Janiak R, Wilson SM, Montague S, Hume JR. Heterogeneity of calcium stores and elementary release events in canine pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol 280: C22-C33, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Janiak, R.1    Wilson, S.M.2    Montague, S.3    Hume, J.R.4
  • 26
    • 39149119639 scopus 로고    scopus 로고
    • Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats
    • Jankov RP, Kantores C, Pan J, Belik J. Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats. Am J Physiol Lung Cellular Mol Physiol 294: L233-L245, 2008.
    • (2008) Am J Physiol Lung Cellular Mol Physiol , vol.294
    • Jankov, R.P.1    Kantores, C.2    Pan, J.3    Belik, J.4
  • 27
    • 84858176258 scopus 로고    scopus 로고
    • Chronic hypoxia upregulates pulmonary arterial ASIC1: a novel mechanism of enhanced store-operated Ca2+ entry and receptor-dependent vasoconstriction
    • Jernigan NL, Herbert LM, Walker BR, Resta TC. Chronic hypoxia upregulates pulmonary arterial ASIC1: a novel mechanism of enhanced store-operated Ca2+ entry and receptor-dependent vasoconstriction. Am J Physiol Cell Physiol 302: C931-C940, 2012.
    • (2012) Am J Physiol Cell Physiol , vol.302
    • Jernigan, N.L.1    Herbert, L.M.2    Walker, B.R.3    Resta, T.C.4
  • 29
    • 52649126946 scopus 로고    scopus 로고
    • Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia
    • Jernigan NL, Walker BR, Resta TC. Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia. Am J Physiol Lung Cell Mol Physiol 295: L515-L529, 2008.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295
    • Jernigan, N.L.1    Walker, B.R.2    Resta, T.C.3
  • 30
    • 0035661773 scopus 로고    scopus 로고
    • Regulation of cardiac and smooth muscle Ca2+ channels (CaV1.2a, b) by protein kinases
    • Keef KD, Hume JR, Zhong J. Regulation of cardiac and smooth muscle Ca2+ channels (CaV1.2a, b) by protein kinases. Am J Physiol Cell Physiol 281: C1743-C1756, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Keef, K.D.1    Hume, J.R.2    Zhong, J.3
  • 31
    • 0021917682 scopus 로고
    • Calcium channel blockers in hypoxic pulmonary hypertension
    • Kennedy TP, Michael JR, Summer W. Calcium channel blockers in hypoxic pulmonary hypertension. Am J Med 78: 18-26, 1985.
    • (1985) Am J Med , vol.78 , pp. 18-26
    • Kennedy, T.P.1    Michael, J.R.2    Summer, W.3
  • 32
    • 53449101190 scopus 로고    scopus 로고
    • Cytoskeletal remodeling in differentiated vascular smooth muscle is actin isoform dependent and stimulus dependent
    • Kim HR, Gallant C, Leavis PC, Gunst SJ, Morgan KG. Cytoskeletal remodeling in differentiated vascular smooth muscle is actin isoform dependent and stimulus dependent. Am J Physiol Cell Physiol 295: C768-C778, 2008.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Kim, H.R.1    Gallant, C.2    Leavis, P.C.3    Gunst, S.J.4    Morgan, K.G.5
  • 36
    • 58649106653 scopus 로고    scopus 로고
    • Genetic evidence for functional role of ryanodine receptor 1 in pulmonary artery smooth muscle cells
    • Li X-Q, Zheng Y-M, Rathore R, Ma J, Takeshima H, Wang Y-X. Genetic evidence for functional role of ryanodine receptor 1 in pulmonary artery smooth muscle cells. Pflugers Arch 457: 771-783, 2009.
    • (2009) Pflugers Arch , vol.457 , pp. 771-783
    • Li, X.-Q.1    Zheng, Y.-M.2    Rathore, R.3    Ma, J.4    Takeshima, H.5    Wang, Y.-X.6
  • 37
    • 78649479405 scopus 로고    scopus 로고
    • Hypoxia induces intracellular Ca2+ release by causing reactive oxygen species-mediated dissociation of FK506-binding protein 12.6 from ryanodine receptor 2 in pulmonary artery myocytes
    • Liao B, Zheng YM, Yadav VR, Korde AS, Wang YX. Hypoxia induces intracellular Ca2+ release by causing reactive oxygen species-mediated dissociation of FK506-binding protein 12.6 from ryanodine receptor 2 in pulmonary artery myocytes. Antioxid Redox Signal 14: 37-47, 2011.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 37-47
    • Liao, B.1    Zheng, Y.M.2    Yadav, V.R.3    Korde, A.S.4    Wang, Y.X.5
  • 38
    • 4444352981 scopus 로고    scopus 로고
    • Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension
    • Lin M-J, Leung GPH, Zhang W-M, Yang X-R, Yip K-P, Tse C-M, Sham JSK. Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension. Circ Res 95: 496-505, 2004.
    • (2004) Circ Res , vol.95 , pp. 496-505
    • Lin, M.-J.1    Leung, G.P.H.2    Zhang, W.-M.3    Yang, X.-R.4    Yip, K.-P.5    Tse, C.-M.6    Sham, J.S.K.7
  • 43
    • 84861140168 scopus 로고    scopus 로고
    • Kinase-dependent activation of voltage-gated Ca2+ channels by ET-1 in pulmonary arterial myocytes during chronic hypoxia
    • Luke T, Maylor J, Undem C, Sylvester JT, Shimoda LA. Kinase-dependent activation of voltage-gated Ca2+ channels by ET-1 in pulmonary arterial myocytes during chronic hypoxia. Am J Physiol Lung Cellular Mol Physiol 302: L1128-L1139, 2012.
    • (2012) Am J Physiol Lung Cellular Mol Physiol , vol.302
    • Luke, T.1    Maylor, J.2    Undem, C.3    Sylvester, J.T.4    Shimoda, L.A.5
  • 44
    • 0022362903 scopus 로고
    • Hypoxia-induced activation in small isolated pulmonary arteries from the cat
    • Madden JA, Dawson CA, Harder DR. Hypoxia-induced activation in small isolated pulmonary arteries from the cat. J Appl Physiol 59: 113-118, 1985.
    • (1985) J Appl Physiol , vol.59 , pp. 113-118
    • Madden, J.A.1    Dawson, C.A.2    Harder, D.R.3
  • 47
    • 0036606183 scopus 로고    scopus 로고
    • Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase
    • Mita M, Yanagihara H, Hishinuma S, Saito M, Walsh MP. Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase. Biochem J 364: 431-440, 2002.
    • (2002) Biochem J , vol.364 , pp. 431-440
    • Mita, M.1    Yanagihara, H.2    Hishinuma, S.3    Saito, M.4    Walsh, M.P.5
  • 48
    • 80052317552 scopus 로고    scopus 로고
    • Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels
    • Mungai PT, Waypa GB, Jairaman A, Prakriya M, Dokic D, Ball MK, Schumacker PT. Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels. Mol Cell Biol 31: 3531-3545, 2011.
    • (2011) Mol Cell Biol , vol.31 , pp. 3531-3545
    • Mungai, P.T.1    Waypa, G.B.2    Jairaman, A.3    Prakriya, M.4    Dokic, D.5    Ball, M.K.6    Schumacker, P.T.7
  • 51
    • 14144251789 scopus 로고    scopus 로고
    • Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction
    • Naik JS, Earley S, Resta TC, Walker BR. Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction. J Appl Physiol 98: 1119-1124, 2005.
    • (2005) J Appl Physiol , vol.98 , pp. 1119-1124
    • Naik, J.S.1    Earley, S.2    Resta, T.C.3    Walker, B.R.4
  • 52
  • 55
    • 84875943954 scopus 로고    scopus 로고
    • Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2
    • Norton CE, Broughton BR, Jernigan NL, Walker BR, Resta TC. Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2. Antioxid Redox Signal 18: 1777-1788, 2013.
    • (2013) Antioxid Redox Signal , vol.18 , pp. 1777-1788
    • Norton, C.E.1    Broughton, B.R.2    Jernigan, N.L.3    Walker, B.R.4    Resta, T.C.5
  • 57
    • 0025304799 scopus 로고
    • Protein kinase C influences rat pulmonary vascular reactivity
    • Orton EC, Raffestin B, McMurtry IF. Protein kinase C influences rat pulmonary vascular reactivity. Am Rev Respir Dis 141: 654-658, 1990.
    • (1990) Am Rev Respir Dis , vol.141 , pp. 654-658
    • Orton, E.C.1    Raffestin, B.2    McMurtry, I.F.3
  • 59
    • 0026560976 scopus 로고
    • Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction
    • Post JM, Hume JR, Archer SL, Weir EK. Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction. Am J Physiol Cell Physiol 262: C882-C890, 1992.
    • (1992) Am J Physiol Cell Physiol , vol.262
    • Post, J.M.1    Hume, J.R.2    Archer, S.L.3    Weir, E.K.4
  • 60
    • 84863551553 scopus 로고    scopus 로고
    • Evaluation of clinical efficacy of fasudil for the treatment of pulmonary arterial hypertension
    • Raja SG. Evaluation of clinical efficacy of fasudil for the treatment of pulmonary arterial hypertension. Recent Pat Cardiovasc Drug Discov 7: 100-104, 2012.
    • (2012) Recent Pat Cardiovasc Drug Discov , vol.7 , pp. 100-104
    • Raja, S.G.1
  • 61
    • 53449086013 scopus 로고    scopus 로고
    • Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCe{open} signaling axis in pulmonary artery smooth muscle cells
    • Rathore R, Zheng Y-M, Niu C-F, Liu Q-H, Korde A, Ho Y-S, Wang Y-X. Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCe{open} signaling axis in pulmonary artery smooth muscle cells. Free Radical Biol Med 45: 1223-1231, 2008.
    • (2008) Free Radical Biol Med , vol.45 , pp. 1223-1231
    • Rathore, R.1    Zheng, Y.-M.2    Niu, C.-F.3    Liu, Q.-H.4    Korde, A.5    Ho, Y.-S.6    Wang, Y.-X.7
  • 63
    • 0033822011 scopus 로고    scopus 로고
    • Inhibition of sustained hypoxic vasoconstriction by Y-27632 in isolated intrapulmonary arteries and perfused lung of the rat
    • Robertson TP, Dipp M, Ward JPT, Aaronson PI, Evans AM. Inhibition of sustained hypoxic vasoconstriction by Y-27632 in isolated intrapulmonary arteries and perfused lung of the rat. Br J Pharmacol 131: 5-9, 2000.
    • (2000) Br J Pharmacol , vol.131 , pp. 5-9
    • Robertson, T.P.1    Dipp, M.2    Ward, J.P.T.3    Aaronson, P.I.4    Evans, A.M.5
  • 64
    • 0034659397 scopus 로고    scopus 로고
    • Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat
    • Robertson TP, Hague D, Aaronson PI, Ward JPT. Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat. J Physiol 525: 669-680, 2000.
    • (2000) J Physiol , vol.525 , pp. 669-680
    • Robertson, T.P.1    Hague, D.2    Aaronson, P.I.3    Ward, J.P.T.4
  • 67
    • 0141794500 scopus 로고    scopus 로고
    • Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction
    • Sakurada S, Takuwa N, Sugimoto N, Wang Y, Seto M, Sasaki Y, Takuwa Y. Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction. Circ Res 93: 548-556, 2003.
    • (2003) Circ Res , vol.93 , pp. 548-556
    • Sakurada, S.1    Takuwa, N.2    Sugimoto, N.3    Wang, Y.4    Seto, M.5    Sasaki, Y.6    Takuwa, Y.7
  • 68
    • 0033697035 scopus 로고    scopus 로고
    • l-type Ca(2+) channels, resting [Ca(2+)](i), and ET-1-induced responses in chronically hypoxic pulmonary myocytes
    • Shimoda LA, Sham JS, Shimoda TH, Sylvester JT. l-type Ca(2+) channels, resting [Ca(2+)](i), and ET-1-induced responses in chronically hypoxic pulmonary myocytes. Am J Physiol Lung Cell Mol Physiol 279: L884-L894, 2000.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Shimoda, L.A.1    Sham, J.S.2    Shimoda, T.H.3    Sylvester, J.T.4
  • 69
    • 0028011920 scopus 로고
    • Chronic hypoxia is associated with reduced delayed rectifier K+ current in rat pulmonary artery muscle cells
    • Smirnov S, Robertson T, Ward J, Aaronson P. Chronic hypoxia is associated with reduced delayed rectifier K+ current in rat pulmonary artery muscle cells. Am J Physiol 266: H365-H370, 1994.
    • (1994) Am J Physiol , vol.266
    • Smirnov, S.1    Robertson, T.2    Ward, J.3    Aaronson, P.4
  • 70
    • 0141841763 scopus 로고    scopus 로고
    • Capacitative calcium entry as a pulmonary specific vasoconstrictor mechanism in small muscular arteries of the rat
    • Snetkov VA, Aaronson PI, Ward JP, Knock GA, Robertson TP. Capacitative calcium entry as a pulmonary specific vasoconstrictor mechanism in small muscular arteries of the rat. Br J Pharmacol 140: 97-106, 2003.
    • (2003) Br J Pharmacol , vol.140 , pp. 97-106
    • Snetkov, V.A.1    Aaronson, P.I.2    Ward, J.P.3    Knock, G.A.4    Robertson, T.P.5
  • 72
    • 78649448297 scopus 로고    scopus 로고
    • Rat strain differences in pulmonary artery smooth muscle Ca(2+) Entry following chronic hypoxia
    • Snow JB, Kanagy NL, Walker BR, Resta TC. Rat strain differences in pulmonary artery smooth muscle Ca(2+) Entry following chronic hypoxia. Microcirculation 22: 1-12, 2009.
    • (2009) Microcirculation , vol.22 , pp. 1-12
    • Snow, J.B.1    Kanagy, N.L.2    Walker, B.R.3    Resta, T.C.4
  • 74
    • 84898033404 scopus 로고    scopus 로고
    • Role of mitochondrial reactive oxygen species and actin polymerization in PKC-dependent constriction of small pulmonary but not mesenteric arteries
    • Snow J, Sands M, Gonzalez Bosc LV, Walker BR, Resta TC. Role of mitochondrial reactive oxygen species and actin polymerization in PKC-dependent constriction of small pulmonary but not mesenteric arteries. FASEB J 26: 873.15, 2012.
    • (2012) FASEB J , vol.26 , pp. 87315
    • Snow, J.1    Sands, M.2    Gonzalez Bosc, L.V.3    Walker, B.R.4    Resta, T.C.5
  • 75
    • 0141751697 scopus 로고    scopus 로고
    • Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase
    • Somlyo AP, Somlyo AV. Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83: 1325-1358, 2003.
    • (2003) Physiol Rev , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 76
    • 84858184804 scopus 로고    scopus 로고
    • STIM2 contributes to enhanced store-operated Ca2+ entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension
    • Song M, Makino A, Yuan JXJ. STIM2 contributes to enhanced store-operated Ca2+ entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. J Cell Mol Med 14: 1890-1903, 2010.
    • (2010) J Cell Mol Med , vol.14 , pp. 1890-1903
    • Song, M.1    Makino, A.2    Yuan, J.X.J.3
  • 77
    • 33749345684 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms
    • Stenmark KR, Fagan KA, Frid MG. Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res 99: 675-691, 2006.
    • (2006) Circ Res , vol.99 , pp. 675-691
    • Stenmark, K.R.1    Fagan, K.A.2    Frid, M.G.3
  • 78
    • 84875370485 scopus 로고    scopus 로고
    • Evidence for the role of phosphatidylcholine-specific phospholipase C in sustained hypoxic pulmonary vasoconstriction
    • Strielkov IV, Kizub IV, Khromov AS, Soloviev AI. Evidence for the role of phosphatidylcholine-specific phospholipase C in sustained hypoxic pulmonary vasoconstriction. Vascul Pharmacol 58: 292-298, 2013.
    • (2013) Vascul Pharmacol , vol.58 , pp. 292-298
    • Strielkov, I.V.1    Kizub, I.V.2    Khromov, A.S.3    Soloviev, A.I.4
  • 79
    • 84864297897 scopus 로고    scopus 로고
    • Chronic hypoxia-induced upregulation of Ca2+-activated Cl- channel in pulmonary arterial myocytes: a mechanism contributing to enhanced vasoreactivity
    • Sun H, Xia Y, Paudel O, Yang X-R, Sham JSK. Chronic hypoxia-induced upregulation of Ca2+-activated Cl- channel in pulmonary arterial myocytes: a mechanism contributing to enhanced vasoreactivity. J Physiol 590: 3507-3521, 2012.
    • (2012) J Physiol , vol.590 , pp. 3507-3521
    • Sun, H.1    Xia, Y.2    Paudel, O.3    Yang, X.-R.4    Sham, J.S.K.5
  • 80
    • 0020135694 scopus 로고
    • Membrane properties of smooth muscle cells in pulmonary hypertensive rats
    • Suzuki H, Twarog BM. Membrane properties of smooth muscle cells in pulmonary hypertensive rats. Am J Physiol Heart Circ Physiol 242: H907-H915, 1982.
    • (1982) Am J Physiol Heart Circ Physiol , vol.242
    • Suzuki, H.1    Twarog, B.M.2
  • 83
    • 0036087476 scopus 로고    scopus 로고
    • Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscle
    • Tang W-X, Chen Y-F, Zou A-P, Campbell WB, Li P-L. Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscle. Am J Physiol Heart Circ Physiol 282: H1304-H1310, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Tang, W.-X.1    Chen, Y.-F.2    Zou, A.-P.3    Campbell, W.B.4    Li, P.-L.5
  • 84
    • 37549033243 scopus 로고    scopus 로고
    • A USA-based registry for pulmonary arterial hypertension: 1982-2006
    • Thenappan T, Shah SJ, Rich S, Gomberg-Maitland M. A USA-based registry for pulmonary arterial hypertension: 1982-2006. Eur Respir J 30: 1103-1110, 2007.
    • (2007) Eur Respir J , vol.30 , pp. 1103-1110
    • Thenappan, T.1    Shah, S.J.2    Rich, S.3    Gomberg-Maitland, M.4
  • 85
    • 8644286380 scopus 로고    scopus 로고
    • Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C
    • Tsai BM, Wang M, Pitcher JM, Meldrum KK, Meldrum DR. Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C. Am J Physiol Lung Cellular Mol Physiol 287: L1215-L1219, 2004.
    • (2004) Am J Physiol Lung Cellular Mol Physiol , vol.287
    • Tsai, B.M.1    Wang, M.2    Pitcher, J.M.3    Meldrum, K.K.4    Meldrum, D.R.5
  • 86
    • 0242594742 scopus 로고    scopus 로고
    • K+ depolarization induces RhoA kinase translocation to caveolae and Ca2+ sensitization of arterial muscle
    • Urban NH, Berg KM, Ratz PH. K+ depolarization induces RhoA kinase translocation to caveolae and Ca2+ sensitization of arterial muscle. Am J Physiol Cell Physiol 285: C1377-C1385, 2003.
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Urban, N.H.1    Berg, K.M.2    Ratz, P.H.3
  • 87
    • 79251509290 scopus 로고    scopus 로고
    • Effects of acute Rho kinase inhibition on chronic hypoxia-induced changes in proximal and distal pulmonary arterial structure and function
    • Vanderpool RR, Kim AR, Molthen R, Chesler NC. Effects of acute Rho kinase inhibition on chronic hypoxia-induced changes in proximal and distal pulmonary arterial structure and function. J Appl Physiol 110: 188-198, 2011.
    • (2011) J Appl Physiol , vol.110 , pp. 188-198
    • Vanderpool, R.R.1    Kim, A.R.2    Molthen, R.3    Chesler, N.C.4
  • 89
    • 84871919065 scopus 로고    scopus 로고
    • The role of actin filament dynamics in the myogenic response of cerebral resistance arteries
    • Walsh MP, Cole WC. The role of actin filament dynamics in the myogenic response of cerebral resistance arteries. J Cereb Blood Flow Metab 33: 1-12, 2013.
    • (2013) J Cereb Blood Flow Metab , vol.33 , pp. 1-12
    • Walsh, M.P.1    Cole, W.C.2
  • 92
    • 84863897408 scopus 로고    scopus 로고
    • Ca2+ responses of pulmonary arterial myocytes to acute hypoxia require release from ryanodine and inositol trisphosphate receptors in sarcoplasmic reticulum
    • Wang J, Shimoda LA, Sylvester JT. Ca2+ responses of pulmonary arterial myocytes to acute hypoxia require release from ryanodine and inositol trisphosphate receptors in sarcoplasmic reticulum. Am J Physiol Lung Cellular Mol Physiol 303: L161-L168, 2012.
    • (2012) Am J Physiol Lung Cellular Mol Physiol , vol.303
    • Wang, J.1    Shimoda, L.A.2    Sylvester, J.T.3
  • 93
    • 33746543743 scopus 로고    scopus 로고
    • Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells
    • Wang J, Weigand L, Lu W, Sylvester JT, Semenza GL, Shimoda LA. Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells. Circ Res 98: 1528-1537, 2006.
    • (2006) Circ Res , vol.98 , pp. 1528-1537
    • Wang, J.1    Weigand, L.2    Lu, W.3    Sylvester, J.T.4    Semenza, G.L.5    Shimoda, L.A.6
  • 97
    • 20844432485 scopus 로고    scopus 로고
    • Inhibition of hypoxic pulmonary vasoconstriction by antagonists of store-operated Ca2+ and nonselective cation channels
    • Weigand L, Foxson J, Wang J, Shimoda LA, Sylvester JT. Inhibition of hypoxic pulmonary vasoconstriction by antagonists of store-operated Ca2+ and nonselective cation channels. Am J Physiol Lung Cell Mol Physiol 289: L5-L13, 2005.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.289
    • Weigand, L.1    Foxson, J.2    Wang, J.3    Shimoda, L.A.4    Sylvester, J.T.5
  • 98
    • 33644837177 scopus 로고    scopus 로고
    • Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats
    • Weigand L, Sylvester JT, Shimoda LA. Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 290: L284-L290, 2006.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290
    • Weigand, L.1    Sylvester, J.T.2    Shimoda, L.A.3
  • 100
    • 0034105359 scopus 로고    scopus 로고
    • Effects of protein tyrosine kinase inhibitors on voltage-operated calcium channel currents in vascular smooth muscle cells and pp60c-src kinase activity
    • Wijetunge S, Lymn JS, Hughes AD. Effects of protein tyrosine kinase inhibitors on voltage-operated calcium channel currents in vascular smooth muscle cells and pp60c-src kinase activity. Br J Pharmacol 129: 1347-1354, 2000.
    • (2000) Br J Pharmacol , vol.129 , pp. 1347-1354
    • Wijetunge, S.1    Lymn, J.S.2    Hughes, A.D.3
  • 102
    • 33744508706 scopus 로고    scopus 로고
    • Agonist- and depolarization-induced signals for myosin light chain phosphorylation and force generation of cultured vascular smooth muscle cells
    • Woodsome TP, Polzin A, Kitazawa K, Eto M, Kitazawa T. Agonist- and depolarization-induced signals for myosin light chain phosphorylation and force generation of cultured vascular smooth muscle cells. J Cell Sci 119: 1769-1780, 2006.
    • (2006) J Cell Sci , vol.119 , pp. 1769-1780
    • Woodsome, T.P.1    Polzin, A.2    Kitazawa, K.3    Eto, M.4    Kitazawa, T.5
  • 106
    • 84865604742 scopus 로고    scopus 로고
    • Deciphering actin cytoskeletal function in the contractile vascular smooth muscle cell
    • Yamin R, Morgan KG. Deciphering actin cytoskeletal function in the contractile vascular smooth muscle cell. J Physiol 590: 4145-4154, 2012.
    • (2012) J Physiol , vol.590 , pp. 4145-4154
    • Yamin, R.1    Morgan, K.G.2
  • 109
    • 34447506708 scopus 로고    scopus 로고
    • Upregulation of Na+/Ca2+ exchanger contributes to the enhanced Ca2+ entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension
    • Zhang S, Dong H, Rubin LJ, Yuan JX-J. Upregulation of Na+/Ca2+ exchanger contributes to the enhanced Ca2+ entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Am J Physiol Cell Physiol 292: C2297-C2305, 2007.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Zhang, S.1    Dong, H.2    Rubin, L.J.3    Yuan, J.-J.4
  • 114
    • 68749101239 scopus 로고    scopus 로고
    • Original research: role of phosphodiesterases in modulation of BKCa channels in hypertensive pulmonary arterial smooth muscle
    • Zhu S, White RE, Barman SA. Original research: role of phosphodiesterases in modulation of BKCa channels in hypertensive pulmonary arterial smooth muscle. Ther Adv Respir Dis 2: 119-127, 2008.
    • (2008) Ther Adv Respir Dis , vol.2 , pp. 119-127
    • Zhu, S.1    White, R.E.2    Barman, S.A.3


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