Pulmonary artery smooth muscle cells from normal subjects and IPAH patients show divergent cAMP-mediated effects on TRPC expression and capacitative Ca2+ entry

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 5, 2007, Pages

  Zhang, Shen ^a   Patel, Hemal H ^a   Murray, Fiona ^a   Remillard, Carmelle V ^a   Schach, Christian ^a   Thistlethwaite, Patricia A ^a   Insel, Paul A ^a,b   Yuan, Jason X J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenosine 3 ,5 cyclic monophosphate; Idiopathic pulmonary arterial hypertension; Pulmonary vascular remodeling; Transient receptor potential channel

Indexed keywords

ADENYLATE CYCLASE; CALCIUM; CATION CHANNEL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; FORSKOLIN; ILOPROST; ISOBUTYLMETHYLXANTHINE; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ATTENUATION; CASE REPORT; CELL ACTIVITY; CELL PROLIFERATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IDIOPATHIC PULMONARY HYPERTENSION; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; SMOOTH MUSCLE FIBER; UPREGULATION;

ADULT; CALCIUM; CALCIUM SIGNALING; CYCLIC AMP; FEMALE; GENE EXPRESSION REGULATION; HUMANS; HYPERTENSION, PULMONARY; MALE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; PULMONARY ARTERY; TRPC CATION CHANNELS;

EID: 34447286761     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00214.2006     Document Type: Article

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