Synergistic interaction between endothelium-derived NO and prostacyclin in pulmonary artery: Potential role for K+(ATP) channels

British Journal of Pharmacology

Volumn 121, Issue 2, 1997, Pages 271-279

  Gambone, Linda M ^a   Murray, Paul A ^b   Flavahan, Nicholas A ^a,c  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

A23187; Acetylcholine; Bradykinin; EDHF; Indomethacin; L NAME

Indexed keywords

ACETYLCHOLINE; BRADYKININ; CALCIMYCIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; GLIBENCLAMIDE; INDOMETACIN; LINSIDOMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; POTASSIUM CHANNEL; PROSTACYCLIN; PROSTAGLANDIN SYNTHASE;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; ENZYME INHIBITION; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; VASCULAR ENDOTHELIUM;

EID: 0031000110     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701082     Document Type: Article

References (46)

1. BOLTON, T.B., LANG, R.J. & TAKEWAKI, T. (1984). Mechanisms of action of noradrenaline and carbachol on smooth muscle of guinea-pig anterior mesenteric artery. J. Physiol., 351, 549-572.
2. COGHLAN, V.M., HAUSKEN, Z.E. & SCOTT, J.D. (1995). Subcellular targetting of kinases and phosphatases by association with bifunctional anchoring proteins. Biochem. Soc. Trans., 23, 592-596.
3. DAVIES, P.F. (1995). Flow-mediated endothelial mechanotransduction. Physiol. Rev., 75, 519-560.
4. ECKLY, A.E. & LUGNIER, C. (1994). Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway. Br. J. Pharmacol., 113, 445-450.
5. FLAVAHAN, N.A., ALESKOWITCH, T.D. & MURRAY, P.A. (1994). Endothelial and vascular smooth muscle responses are altered following left lung autotransplantation. Am. J. Physiol., 266, H2026-H2032.
6. FLAVAHAN, N.A. & VANHOUTTE, P.M. (1988). Threshold phenomena and interactions between receptors. J. Cardiovasc. Pharmacol., 11 (Suppl 1), S67-S72.
7. FLAVAHAN, N.A. & VANHOUTTE, P.M. (1995). Endothelial cell signaling and endothelial dysfunction. Am. J. Hypertens., 8, 28S-41S.
8. FURCHGOTT, R.F. & VANHOUTTE, P.M. (1989). Endothelium-derived relaxing and contracting factors. FASEB J., 3, 2007-2018.
9. GROVER, G.J., D'ALONZO, A.J., SLEPH, P.G., DZWONCZYK, S., HESS, T.A. & DARBENZIO, R.B. (1994). The cardioprotective and electrophysiological effects of cromakalim are attenuated by meclofenamate through a cyclooxygenase-independent mechanism. J. Pharmacol. Exp. Ther., 269, 536-540.
10. HECKER, M., BARA, A.T., BAUERSACHS, J. & BUSSE, R. (1994). Characterization of endothelium-derived hyperpolarizing factor as a cytochrome P450-derived arachidonic acid metabolite in mammals. J. Physiol., 481, 407-414.
11. + channels in follicular cells from Xenopus oocyte. Pflugers Arch., 424, 113-121.
12. IVORRA, M.D., LE BEC, A. & LUGNIER, C. (1992). Characterization of membrane-bound cyclic nucleotide phosphodiesterases from bovine aortic smooth muscle. J. Cardovasc. Pharmacol., 19, 532-540.
13. JACKSON, W.F., KONIG, A., DAMBACHER, T. & BUSSE, R. (1993). Prostacyclin-induced vasodilation in rabbit heart is mediated by ATP-sensitive potassium channels. Am. J. Physiol., 264, H238-H243.
14. + channels in rat aorta and brain microvascular endothelial cells. Am. J. Physiol., 265, C812-821.
15. KATNIK, C. & ADAMS, D.J. (1995). An ATP-sensitive potassium conductance in rabbit arterial endothelial cells. J. Physiol., 485, 595-606.
16. 2 receptors and cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA., 92, 12441-12445.
17. +-channels. Am. J. Physiol., 271, H1498-H1506.
18. KOVITZ, K.L., ALESKOWITCH, T.D., SYLVESTER, J.T. & FLAVAHAN, N.A. (1993). Endothelium derived contracting and relaxing factors contribute to hypoxic responses of pulmonary arteries. Am. J. Physiol., 256, H1139-H1148.
19. ω nitro-1-arginine methyl ester on electrical activity and ion channels of mouse pancreatic B cells. Biochem. Biophys. Res. Commun., 224, 199-205.
20. + channels in cultured vascular smooth muscle cells. Circ. Res., 74, 471-476.
21. LIDBURY, P.S., ANTUNES, E., DE NUCCI, G. & VANE, J.R. (1989). Interactions of iloprost and sodium nitroprusside on vascular smooth muscle and platelet aggregation. Br. J. Pharmacol., 98, 1275-1280.
22. + channel opening by stimulation of adenylyl cyclase in rat isolated aorta. Br. J. Pharmacol., 115, 515-521.
23. ATP-channels. Br. J. Pharmacol., (in press).
24. LOSCALZO, J. & WELCH, G. (1995). Nitric oxide and its role in the cardiovascular system. Prog. Cardiovasc Dis., 38, 87-104.
25. LUCKHOFF, A., POHL, U., MÜLSCH, A. & BUSSE, R. (1988). Differential role of extra- and intracellular calcium in the release of EDRF and prostacyclin from cultured endothelial cells. Br. J. Pharmacol., 95, 189-196.
26. LUGNIER, C. & KOMAS, N. (1993). Modulation of vascular cyclic nucleotide phosphodiesterases by cyclic GMP: role in vasodilatation. Eur. Heart J., 14 (suppl. I), 141-148.
27. MAURICE, D.H., CRANKSHAW, D. & HASLAM, R.J. (1991). Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle. Eur. J. Pharmacol., 192, 235-242.
28. MAURICE D.H. & HASLAM, R.J. (1990). Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: Inhibition of cyclic AMP breakdown by cyclic GMP. Mol. Pharmacol., 37, 671-681.
29. MCCULLOCH, A.I. & RANDALL, M.D. (1996). Modulation of vasorelaxant responses to potassium channel openers by basal nitric oxide in the rat isolated superior mesenteric arterial bed. Br. J. Pharmacol., 117, 859-866.
30. + channel activity involves phosphorylation processes. Proc. Natl. Acad. Sci. U.S.A., 91, 8077-8081.
31. + channels in insulinoma cells are activated by nonesterified fatty acids. Biochemistry, 31, 4656-4661.
32. MURPHY, M. & BRAYDEN, J.E. (1995). Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels. J. Physiol., 486, 47-58.
33. NAGAO, T. & VANHOUTTE, P.M. (1992). Hyperpolarization as a mechanism for endothelium-dependent relaxations in the porcine coronary artery. J. Physiol., 445, 355-367.
34. PARKINGTON, H.C., TARE, M., TONTA, M.A. & COLEMAN, H.A. (1993). Stretch revealed three components in the hyperpolarization of guinea-pig coronary artery in response to acetylcholine. J. Physiol., 465, 459-476.
35. PARKINGTON, H.C., TONTA, M.A., COLEMAN, H.A. & TARE, M. (1995). Role of membrane potential in endothelium-dependent relaxation of guinea-pig coronary arterial smooth muscle. J. Physiol., 484, 469-480.
36. PARSAEE, H., MCEWAN, J.R., JOSEPH, S. & MACDERMOT, J. (1992). Differential sensitivities of the prostacyclin and nitric oxide biosynthetic pathways to cytosolic calcium in bovine aortic endothelial cells. Br. J. Pharmacol., 107, 1013-1019.
37. RABE, K.F., TENOR, H., DENT, C., SCHUDT, C., NAKASHIMA, M. & MAGNUSSEN, H. (1994). Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors. Am. J. Physiol., 266, L536-L543.
38. RAND, V.E. & GARLAND, C.J. (1992). Endothelium-dependent relaxation to acetylcholine in the rabbit basilar artery: importance of membrane hyperpolarization. Br. J. Pharmacol., 106, 143-150.
39. SHIMOKAWA, H., FLAVAHAN, N.A., LORENZ, R.R. & VANHOUTTE, P.M. (1988). Prostacyclin releases endothelium-derived relaxing factor and potentiates its action in coronary arteries of the pig. Br. J. Pharmacol., 95, 1197-1203.
40. + channels in arterial smooth muscle. Science, 245, 177-180.
41. G-monomethyl l-arginine paradoxically relaxes preconstricted canine intrapulmonary arteries. J. Appl. Physiol., 74, 5549-5558.
42. VANHOUTTE, P.M. (1993). Other endothelium-derived vasoactive factors. Circulation, 87, V9-V17.
43. + channel of the rat cortical collecting duct. J. Gen. Physiol., 98, 35-61.
44. + current of coronary smooth muscle cells. Am. J. Physiol., 270, H1957-H1962.
45. + channel, ROMK, by cyclic AMP-dependent protein kinase. J. Biol. Chem., 271, 9313-9319.
46. ZAKHARY, R., GAINE, S.P., DINERMAN, J.L., FLAVAHAN, N.A. & SNYDER, S.H. (1996). Heme oxygenase-2: Endothelial and neuronal localization and role in endothelium-dependent relaxation. Proc. Natl. Acad. Sci. U.S.A., 93, 795-798.