A soluble epoxide hydrolase inhibitor-8-HUDE increases pulmonary vasoconstriction through inhibition of K ATP channels

Pulmonary Pharmacology and Therapeutics

Volumn 25, Issue 1, 2012, Pages 69-76

  Liu, Yun ^a   Zhang, Jing ^b   Yu, Lei ^a   Cao, Fangyuan ^a   Rao, Jingjing ^a   Li, Jing ^a   Jiang, Chun ^c   Falck, J R ^d   Jacobs, Elizabeth R ^e   Zhu, Daling ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^c GEORGIA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

12 (3 hexylureido)dodec 8 enoic acid; 8 HUDE; ATP sensitive K + (K ATP) channels; Epoxyeicosatrienoic acids (EETs); Pulmonary arteries

Indexed keywords

12 (3 HEXYLUREIDO)DODEC 8 ENOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ARACHIDONIC ACID DERIVATIVE; GLIBENCLAMIDE; MESSENGER RNA; PINACIDIL; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; LUNG VASOCONSTRICTION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; RAT; REVIEW; TENSION; WHOLE CELL;

8,11,14-EICOSATRIENOIC ACID; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; CELLS, CULTURED; ENZYME INHIBITORS; EPOXIDE HYDROLASES; FATTY ACIDS, MONOUNSATURATED; FEMALE; HEK293 CELLS; HUMANS; KATP CHANNELS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PULMONARY ARTERY; PULMONARY CIRCULATION; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, DRUG; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 84856780301     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2011.11.005     Document Type: Review

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