Increased plasma levels of adrenomedullin, a vasoactive peptide, in patients with end-stage pulmonary disease

Regulatory Peptides

Volumn 124, Issue 1-3, 2005, Pages 187-193

  Vizza, C D ^a   Letizia, C ^a,c   Sciomer, S ^a   Naeije, R ^b   Della Rocca, G ^a   Di Roma, A ^a   Musaro S ^a   Quattrucci, S ^a   Gaudio, C ^a   Battagliese, A ^a   Badagliacca, R ^a   D'Erasmo, E ^a   Fedele, F ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

^c POLICLINICO UMBERTO I   (Italy)

Author keywords

Adrenomedullin; End stage pulmonary disease; Pulmonary hemodynamics; Pulmonary hypertension

Indexed keywords

ADRENOMEDULLIN; PEPTIDE;

ADULT; ARTICLE; BLOOD ANALYSIS; BLOOD CHEMISTRY; BLOOD GAS ANALYSIS; CASE CONTROL STUDY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYSTIC FIBROSIS; DISEASE SEVERITY; DOPPLER ECHOGRAPHY; FEMALE; HEART HEMODYNAMICS; HEART RATE; HUMAN; LUNG ARTERY PRESSURE; LUNG CLEARANCE; LUNG DISEASE; LUNG FIBROSIS; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY HYPERTENSION; SYSTEMIC VASCULAR RESISTANCE; TRANSTHORACIC ECHOCARDIOGRAPHY; TWO DIMENSIONAL ECHOCARDIOGRAPHY;

ADRENOMEDULLIN; ADULT; CYSTIC FIBROSIS; ECHOCARDIOGRAPHY; FEMALE; HUMANS; LUNG DISEASES; MALE; MIDDLE AGED; PEPTIDES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY FIBROSIS;

EID: 8444233995     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2004.07.021     Document Type: Article

References (28)

1. K. Kitamura, K. Kangawa, M. Kawamoto, Y. Ichiki, S. Nakamura, and H. Matsuo Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma Biochem. Biophys. Res. Commun. 192 1993 553 560
2. I.P. Hinson, S. Kapas, and D.M. Smith Adrenomedullin a multifunctional regulatory peptide Endocr. Rev. 21 2000 138 167
3. S. Sugo, N. Minamino, K. Kangawa, K. Miyamoto, K. Kitamura, and J. Sakata Endothelial cells actively sinthetize and secrete adrenomedullin Biochem. Biophys. Res. Commun. 201 1994 642 646
4. T. Nishikimi, M. Kitamura, Y. Saito, K. Shimada, T. Ishimitsu, and M. Takamiya Clinical studies for the site of production and clearance of circulating adrenomedullin in human subjects Hypertension 24 1994 600 604
5. T. Nishikimi, H. Matsuoka, K. Shimada, H. Matsuo, and K. Kangawa Production and clearance sites of two molecular forms of adrenomedullin in human plasma Am. J. Hypertens. 13 2000 1032 1034
6. T. Hishimitsu, T. Nishikimi, Y. Saito, K. Kitamura, T. Eto, and W. Kanga Plasma levels of adrenomedullin a newly identified hypotensive peptide in patients with hypertension and renal failure J. Clin. Invest. 94 1994 2158 2161
7. N. Khono, T. Hanemira, H. Kano, T. Horio, K. Yokokawa, and M. Ikeda Plasma adrenomedullin concentration in essential hypertension Hypertension 27 1996 102 107
8. C. Letizia, G. De Toma, S. Cerci, R. Massa, S. Coassin, and S. Subioli Adrenomedullin levels are high in primary aldosteronism due to adenoma before and after surgical cure Blood Pressure 7 1998 19 23
9. C. Letizia, G. De Toma, C. Caliumi, S. Cerci, R. Massa, and R. Di Iorio Plasma adrenomedullin in patients with adrenal pheochromocytoma Horm. Metab. Res. 33 2001 290 294
10. T. Nishikimi, Y. Saito, K. Kitamura, T. Ishimitsu, T. Eto, and K. Kangawa Increased plasma levels of adrenomedullin in patients with heart failure J. Am. Coll. Cardiol. 26 1995 1424 1431
11. Y. Miyao, T. Nishikimi, Y. Goto, S. Miyazaki, S. Daikoku, and I. Morii Increased plasma levels of adrenomedullin in patients with acute myocardial infarction in proportion to the clinical severity Heart 79 1998 39 44
12. M. Jougusaki, R.J. Rodeheffer, M.M. Redfield, K. Yamamoto, C. Wei, and L.J. McKinley Cardiac secretion of adrenomedullin in human heart failure J. Clin. Invest. 97 1996 2370 2376
13. M. Yoshibayashi, T. Kamiya, K. Kitamura, Y. Saito, K. Kangawa, and T. Nishikimi Plasma levels of adremomedullin in primary and secondary pulmonary hypertension in patients <20 years of age Am. J. Cardiol. 79 1997 1556 1558
14. M. Kakishita, T. Nishikimi, Y. Okano, T. Satoh, S. Kyotani, and N. Nagaya Increased plasma levels of adrenomedullin in patients with pulmonary hypertension Clin. Sci. 96 1999 33 39
15. T. Nishikimi, S. Nagata, T. Sasaki, F. Yoshihara, N. Nagaya, and T. Horio The active molecular form of plasma adrenomedullin is extracted in the pulmonary circle in patients with mitral stenosis: possible role of adrenomedullin in pulmonary hypertension Clin. Sci. 100 2001 61 66
16. F. Yoshihara, T. Nishikimi, T. Horio, C. Yutani, S. Takishita, and H. Matsuo Chronic infusion of adrenomedullin reduces pulmonary hypertension and lessens right ventricular hypertrophy in rats administered monocrotaline Eur. J. Pharmacol. 355 1 1998 33 39
17. N. Nagaya, T. Nishikimi, M. Uematsu, T. Satoh, H. Oya, and S. Kyotani Haemodynamic and hormonal effects of adrenomedullin in patients with pulmonary hypertension Heart 84 2000 653 658
18. American Thoracic Society Standardization of spirometry-1987 update Am. Rev. Respir. Dis. 136 1987 1285 1298
19. A. Ribeiro, P. Lindmarker, A. Juhlin-Dannfelt, H. Johnsson, and L. Jorfeldt Echocardiography Doppler in pulmonary embolism: right ventricular dysfunction as a predictor of mortality rate Am. Heart J. 134 1997 479 487
20. C. Letizia, S. Cerci, M. Centanni, G. De Toma, S. Subioli, and C. Scuro Circulating levels of adrenomedullin in patients with Addison's disease before and after corticosteroid treatment Clin. Endocrinol. 48 1998 145 148
21. P. Vijay, L. Szekely, T. Sharp, A. Miller, K. Bando, and J.W. Brown Adrenomedullin in patients at high risk for pulmonary hypertension Ann. Thorac. Surg. 66 1998 500 505
22. C.R. Benedict, C.D. Johnstone, D.H. Weiner, M.G. Bourassa, V. Bittner, and R. Kay Relation of neurohormonal activation to clinical variables and degree of ventricular dysfunction: a report from the Registry of Studies of Left Ventricular Dysfunction J. Am. Coll. Cardiol. 23 1994 1410 1423
23. M. Jougasaki, C. Wei, L.J. McKinley, and C. Burnett Elevation of circulating and ventricualr adrenomedullin in human congestive heart failure Circulation 92 1995 286 289
24. I.S. Anand, Y. Chandrashekhar, R. Ferrari, R. Sarma, R. Guleira, and Sk Jindal Pathogenesis of congestive state in chronic obstructive pulmonary disease. Studies of body water and sodium, renal function, hemodynamics, and plasma hormones during edema and recovery Circulation 86 1992 12 21
25. Y. Mitani, J. Maruyama, A. Yokochi, K. Maruyama, T. Yoshimoto, and M. Naruse Modulated vasodilator responses to natriuretic peptides in rats exposed to chronic hypoxia Eur. Respir. J. 15 2000 (Feb.) 400 406
26. L. Zhao, L.A. Brown, A.A. Owji, D.J. Nunez, D.M. Smith, and M.A. Ghatei Adrenomedullin activity in chronically hypoxic rat lungs Am. J. Physiol. 271 1996 H622 H629
27. M. Nootens, E. Kaufmann, T. Rector, C. Toher, D. Judd, and G.S. Francis Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: relation to hemodynamic variables and endothelin levels J. Am. Coll. Cardiol. 26 1995 1581 1585
28. I.M. Keith The role of endogenous lung neuropeptides in regulation of the pulmonary circulation Physiol. Res. 49 2000 519 537