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Volumn , Issue , 2012, Pages 373-415

PET and SPECT reporter gene imaging

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY;

EID: 84906864805     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1142/9789814293686_0013     Document Type: Chapter
Times cited : (3)

References (190)
  • 1
    • 13044260220 scopus 로고    scopus 로고
    • Imaging adenoviral- directed reporter gene expression in living animals with positron emission tomography
    • Gambhir SS, Barrio JR, Phelps ME, Iyer M, Namavari M, Satyamurthy N, et al. Imaging adenoviral- directed reporter gene expression in living animals with positron emission tomography. PNAS. 1999; 96: 2333–2338.
    • (1999) PNAS , vol.96 , pp. 2333-2338
    • Gambhir, S.S.1    Barrio, J.R.2    Phelps, M.E.3    Iyer, M.4    Namavari, M.5    Satyamurthy, N.6
  • 2
    • 0031742514 scopus 로고    scopus 로고
    • Imaging of adenoviral directed herpes simplex virus type 1 thymidine kinase gene expression in mice with ganciclovir
    • Gambhir SS, Barrio J, Wu L, Iyer M, Namavari M, Satyamurthy N, et al. Imaging of adenoviral directed herpes simplex virus type 1 thymidine kinase gene expression in mice with ganciclovir. J Nucl Med. 1998; 39: 2003–2011.
    • (1998) J Nucl Med , vol.39 , pp. 2003-2011
    • Gambhir, S.S.1    Barrio, J.2    Wu, L.3    Iyer, M.4    Namavari, M.5    Satyamurthy, N.6
  • 3
    • 9544242826 scopus 로고    scopus 로고
    • Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy
    • Tjuvajev JG, Finn R, Watanabe K, Joshi R, Oku T, Kennedy J, et al. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res. 1996; 56: 4087–4095.
    • (1996) Cancer Res , vol.56 , pp. 4087-4095
    • Tjuvajev, J.G.1    Finn, R.2    Watanabe, K.3    Joshi, R.4    Oku, T.5    Kennedy, J.6
  • 4
    • 17144471900 scopus 로고    scopus 로고
    • Imaging Herpes virus thymidine kinase gene transfer and expression by positron emission tomography
    • Tjuvajev JG, Avril N, Oku T, Sasajima T, Miyagawa T, Joshi R, et al. Imaging Herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res. 1998; 58: 4333–4341.
    • (1998) Cancer Res , vol.58 , pp. 4333-4341
    • Tjuvajev, J.G.1    Avril, N.2    Oku, T.3    Sasajima, T.4    Miyagawa, T.5    Joshi, R.6
  • 5
    • 0344564162 scopus 로고    scopus 로고
    • Imaging adenoviralmediated herpes virus thymidine kinase gene transfer and expression in vivo
    • Tjuvajev JG, Chen SH, Joshi A, Joshi R, Guo ZS, Balatoni J, et al. Imaging adenoviralmediated herpes virus thymidine kinase gene transfer and expression in vivo. Cancer Res. 1999; 59: 5186–5193.
    • (1999) Cancer Res , vol.59 , pp. 5186-5193
    • Tjuvajev, J.G.1    Chen, S.H.2    Joshi, A.3    Joshi, R.4    Guo, Z.S.5    Balatoni, J.6
  • 6
    • 0000773733 scopus 로고    scopus 로고
    • Imaging gene expression: Concepts and Future Outlook
    • Schiepers C, editor, New York: Springer-Verlag Berlin Heidelberg
    • Gambhir SS. Imaging gene expression: concepts and Future Outlook. In: Schiepers C, editor. Diagnostic nuclear medicine. New York: Springer-Verlag Berlin Heidelberg; 1999. p. 253–271.
    • (1999) Diagnostic Nuclear Medicine , pp. 253-271
    • Gambhir, S.S.1
  • 10
    • 0242385251 scopus 로고    scopus 로고
    • A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography
    • Gambhir SS, Bauer E, Black ME, Liang Q, Kokoris MS, Barrio JR, et al. A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. PNAS. 2000; 97: 2785–2790.
    • (2000) PNAS , vol.97 , pp. 2785-2790
    • Gambhir, S.S.1    Bauer, E.2    Black, M.E.3    Liang, Q.4    Kokoris, M.S.5    Barrio, J.R.6
  • 11
    • 70349248056 scopus 로고    scopus 로고
    • PET imaging of HSV1-tk mutants with acquired specificity toward pyrimidine- and acycloguanosine-based radiotracers
    • Likar Y, Dobrenkov K, Olszewska M, Shenker L, Cai S, Hricak H, et al. PET imaging of HSV1-tk mutants with acquired specificity toward pyrimidine- and acycloguanosine-based radiotracers. Eur J Nucl Med Mol Imaging. 2009; 36: 1273–1282.
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 1273-1282
    • Likar, Y.1    Dobrenkov, K.2    Olszewska, M.3    Shenker, L.4    Cai, S.5    Hricak, H.6
  • 12
    • 44149101969 scopus 로고    scopus 로고
    • A new acycloguanosine- specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs
    • Likar Y, Dobrenkov K, Olszewska M, Vider E, Shenker L, Cai S, et al. A new acycloguanosine- specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs. J Nucl Med. 2008; 49: 713–720.
    • (2008) J Nucl Med , vol.49 , pp. 713-720
    • Likar, Y.1    Dobrenkov, K.2    Olszewska, M.3    Vider, E.4    Shenker, L.5    Cai, S.6
  • 13
    • 0034746372 scopus 로고    scopus 로고
    • Nguyen K, et al. 8-[18F] Fluoropenciclovir: An improved reporter probe for imaging HSV1-tk reporter gene expression in vivo using PET
    • Iyer M, Barrio JR, Namavari M, Bauer E, Satyamurthy N, Nguyen K, et al. 8-[18F] Fluoropenciclovir: an improved reporter probe for imaging HSV1-tk reporter gene expression in vivo using PET. J Nucl Med. 2001; 42: 96–105.
    • (2001) J Nucl Med , vol.42 , pp. 96-105
    • Iyer, M.1    Barrio, J.R.2    Namavari, M.3    Bauer, E.4    Satyamurthy, N.5
  • 14
    • 0033625192 scopus 로고    scopus 로고
    • Synthesis of 8-[18F]Fluoroguanine derivatives: In vivo probes for imaging gene expression with positron emission tomography
    • Namavari M, Barrio J, Toyokuni T, Gambhir S, Cherry S, Herschman H, et al. Synthesis of 8-[18F]Fluoroguanine derivatives: in vivo probes for imaging gene expression with positron emission tomography. Nucl Med Biol. 2000; 27: 157–162.
    • (2000) Nucl Med Biol , vol.27 , pp. 157-162
    • Namavari, M.1    Barrio, J.2    Toyokuni, T.3    Gambhir, S.4    Cherry, S.5    Herschman, H.6
  • 15
    • 37649001958 scopus 로고    scopus 로고
    • Generation of destabilized herpes simplex virus type 1 thymidine kinase as transcription reporter for PET reporter systems in molecular-genetic imaging
    • Hsieh C, Chen F, Wang H, Hwang J, Chang C, Lee Y, et al. Generation of destabilized herpes simplex virus type 1 thymidine kinase as transcription reporter for PET reporter systems in molecular-genetic imaging. J Nucl Med. 2008; 49: 142–150.
    • (2008) J Nucl Med , vol.49 , pp. 142-150
    • Hsieh, C.1    Chen, F.2    Wang, H.3    Hwang, J.4    Chang, C.5    Lee, Y.6
  • 16
    • 0242355152 scopus 로고    scopus 로고
    • Comparison of [18F]FHBG and [14C]FIAU for imaging of HSV1-tk reporter gene expression: Adenoviral infection vs stable transfection
    • Min J, Iyer M, Gambhir SS. Comparison of [18F]FHBG and [14C]FIAU for imaging of HSV1-tk reporter gene expression: adenoviral infection vs stable transfection. Eur J Nucl Med Mol Imaging. 2003; 30: 1547–1560.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 1547-1560
    • Min, J.1    Iyer, M.2    Gambhir, S.S.3
  • 17
    • 6944256513 scopus 로고    scopus 로고
    • A tracer kinetic model for 18F-FHBG for quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using PET
    • Green LA, Nguyen K, Berenji B, Iyer M, Bauer E, Barrio JR, et al. A tracer kinetic model for 18F-FHBG for quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using PET. J Nucl Med. 2004; 45: 1560–1570.
    • (2004) J Nucl Med , vol.45 , pp. 1560-1570
    • Green, L.A.1    Nguyen, K.2    Berenji, B.3    Iyer, M.4    Bauer, E.5    Barrio, J.R.6
  • 18
    • 0035209394 scopus 로고    scopus 로고
    • Preclinical evaluation of the penciclovir analog 9-(4-[18F]fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET
    • Alauddin MA, Shahinian A, Gordon EM, Bading JR, Conti PS. Preclinical evaluation of the penciclovir analog 9-(4-[18F]fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET. J Nucl Med. 2001; 42: 1682–1690.
    • (2001) J Nucl Med , vol.42 , pp. 1682-1690
    • Alauddin, M.A.1    Shahinian, A.2    Gordon, E.M.3    Bading, J.R.4    Conti, P.S.5
  • 19
    • 4644294588 scopus 로고    scopus 로고
    • Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in human breast cancer model
    • Alauddin MA, Shahinian A, Gordon EM, Conti PS. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in human breast cancer model. Mol Imaging. 2004; 3: 76–84.
    • (2004) Mol Imaging , vol.3 , pp. 76-84
    • Alauddin, M.A.1    Shahinian, A.2    Gordon, E.M.3    Conti, P.S.4
  • 20
    • 18244428952 scopus 로고    scopus 로고
    • Synthesis and preliminary evaluation of 9-(4-[18F]-Fluoro-3- Hydroxymethylbutyl)Guanine ([18F]FHBG): A new potential imaging agent for viral infection and gene therapy using PET
    • Alauddin MM, Conti PS. Synthesis and preliminary evaluation of 9-(4-[18F]-Fluoro-3- Hydroxymethylbutyl)Guanine ([18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET. Nucl Med Biol. 1998; 25: 175–180.
    • (1998) Nucl Med Biol , vol.25 , pp. 175-180
    • Alauddin, M.M.1    Conti, P.S.2
  • 21
    • 33745806870 scopus 로고    scopus 로고
    • In vitro evaluation of herpes simplex virus type 1 thymidine kinase reporter system in dynamic studies of transcriptional gene regulation
    • Hsieh C, Liu R, Wang H, Hwang J, Deng W, Chen J, et al. In vitro evaluation of herpes simplex virus type 1 thymidine kinase reporter system in dynamic studies of transcriptional gene regulation. Nucl Med Biol. 2006; 33.
    • (2006) Nucl Med Biol , pp. 33
    • Hsieh, C.1    Liu, R.2    Wang, H.3    Hwang, J.4    Deng, W.5    Chen, J.6
  • 22
    • 0034898675 scopus 로고    scopus 로고
    • Human pharmacokinetic and dosimetry studies of [18F]FHBG: A reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression
    • Yaghoubi SS, Barrio JR, Dahlbom M, Iyer M, Namavari M, Satyamurthy N, et al. Human pharmacokinetic and dosimetry studies of [18F]FHBG: a reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression. J Nucl Med. 2001; 42: 1225–1234.
    • (2001) J Nucl Med , vol.42 , pp. 1225-1234
    • Yaghoubi, S.S.1    Barrio, J.R.2    Dahlbom, M.3    Iyer, M.4    Namavari, M.5    Satyamurthy, N.6
  • 23
    • 33745080072 scopus 로고    scopus 로고
    • Preclinical safety evaluation of 18F-FHBG: A PET reporter probe for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk’s expression
    • Yaghoubi SS, Couto MA, Chen C, Polavaram L, Cui G, Sen L, et al. Preclinical safety evaluation of 18F-FHBG: a PET reporter probe for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk’s expression. J Nucl Med. 2006; 47: 706–715.
    • (2006) J Nucl Med , vol.47 , pp. 706-715
    • Yaghoubi, S.S.1    Couto, M.A.2    Chen, C.3    Polavaram, L.4    Cui, G.5    Sen, L.6
  • 24
    • 0036880269 scopus 로고    scopus 로고
    • A fully automated one pot synthesis of 9-(4-[18F]Fluoro-3-Hydroxymethylbutyl)Guanine for gene therapy studies
    • Penuelas I, Boan JF, Marti-Climent JM, Barajas MA, Narvaiza I, Satyamurthy N, et al. A fully automated one pot synthesis of 9-(4-[18F]Fluoro-3-Hydroxymethylbutyl)Guanine for gene therapy studies. Mol Imaging Biol. 2003; 4: 415–424.
    • (2003) Mol Imaging Biol , vol.4 , pp. 415-424
    • Penuelas, I.1    Boan, J.F.2    Marti-Climent, J.M.3    Barajas, M.A.4    Narvaiza, I.5    Satyamurthy, N.6
  • 26
    • 0034813752 scopus 로고    scopus 로고
    • A simplified one-pot synthesis of 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]FHPG) and 9-(4- [18F]Fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG) for gene therapy
    • Shiue GG, Shiue C, Lee RL, MacDonald D, Hustinx R, Eck SL, et al. A simplified one-pot synthesis of 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]FHPG) and 9-(4- [18F]Fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG) for gene therapy. Nucl Med Biol. 2001; 28: 875–883.
    • (2001) Nucl Med Biol , vol.28 , pp. 875-883
    • Shiue, G.G.1    Shiue, C.2    Lee, R.L.3    Macdonald, D.4    Hustinx, R.5    Eck, S.L.6
  • 27
    • 33645214648 scopus 로고    scopus 로고
    • 18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: In-vitro comparison with other PET tracers
    • Buursma AR, Rutgers V, Hospers GAP, Mulder NH, Vaalburg W, de Vries EFJ. 18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers. Nucl Med Commun. 2006; 27: 25–30.
    • (2006) Nucl Med Commun , vol.27 , pp. 25-30
    • Buursma, A.R.1    Rutgers, V.2    Hospers, G.3    Mulder, N.H.4    Vaalburg, W.5    De Vries, E.6
  • 28
    • 62449145537 scopus 로고    scopus 로고
    • Molecular-genetic PET imaging using an HSV1-tk mutant reporter gene with enhanced specificity to acycloguanosine nucleoside analogs
    • Najjar AM, Nishii R, Maxwell DS, Volgin A, Mukhopadhyay U, Bornmann WG, et al. Molecular-genetic PET imaging using an HSV1-tk mutant reporter gene with enhanced specificity to acycloguanosine nucleoside analogs. J Nucl Med. 2009; 50: 409–416.
    • (2009) J Nucl Med , vol.50 , pp. 409-416
    • Najjar, A.M.1    Nishii, R.2    Maxwell, D.S.3    Volgin, A.4    Mukhopadhyay, U.5    Bornmann, W.G.6
  • 29
    • 34248677836 scopus 로고    scopus 로고
    • Measuring herpes simplex virus thymidine kinase reporter gene expression in vitro
    • Yaghoubi SS, Gambhir SS. Measuring herpes simplex virus thymidine kinase reporter gene expression in vitro. Nat Protoc. 2006; 1: 2137–2142.
    • (2006) Nat Protoc , vol.1 , pp. 2137-2142
    • Yaghoubi, S.S.1    Gambhir, S.S.2
  • 30
    • 34548864644 scopus 로고    scopus 로고
    • PET imaging of herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk reporter gene expression in mice and humans using [18F]FHBG
    • Yaghoubi SS, Gambhir SS. PET imaging of herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk reporter gene expression in mice and humans using [18F]FHBG. Nat Protoc. 2007; 1: 3069–3075.
    • (2007) Nat Protoc , vol.1 , pp. 3069-3075
    • Yaghoubi, S.S.1    Gambhir, S.S.2
  • 31
    • 34548567871 scopus 로고    scopus 로고
    • Studying the biodistribution of positron emission tomography reporter probes in mice
    • Yaghoubi SS, Berger F, Gambhir SS. Studying the biodistribution of positron emission tomography reporter probes in mice. Nat Protoc. 2007; 2: 1752–1755.
    • (2007) Nat Protoc , vol.2 , pp. 1752-1755
    • Yaghoubi, S.S.1    Berger, F.2    Gambhir, S.S.3
  • 32
    • 0002401455 scopus 로고    scopus 로고
    • Evaluation of F-18 9-(4-fluoro-3-hydroxymethylbutyl) guanine ([F-18]FHBG as a PET imaging agent for gene expression in tumor bearing nude mice [Abstract #103]
    • Alauddin MM, Shahinian A, Gordon EM, Conti PS. Evaluation of F-18 9-(4-fluoro-3-hydroxymethylbutyl) guanine [F-18]FHBG as a PET imaging agent for gene expression in tumor bearing nude mice [Abstract #103]. J Nucl Med. 1999; 40: 26P.
    • (1999) J Nucl Med , vol.40 , pp. 26
    • Alauddin, M.M.1    Shahinian, A.2    Gordon, E.M.3    Conti, P.S.4
  • 33
    • 0036324348 scopus 로고    scopus 로고
    • Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression
    • Tjuvajev JG, Doubrovin M, Akhurst T, Cai S, Balatoni J, Alauddin MA, et al. Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression. J Nucl Med. 2002; 43: 1072–1083.
    • (2002) J Nucl Med , vol.43 , pp. 1072-1083
    • Tjuvajev, J.G.1    Doubrovin, M.2    Akhurst, T.3    Cai, S.4    Balatoni, J.5    Alauddin, M.A.6
  • 34
    • 33747062746 scopus 로고    scopus 로고
    • [131I]FIAU labeling of genetically transduced, tumor-reactive lymphocytes: Cell-level dosimetry and dosedependent toxicity
    • Zanzonico P, Koehne G, Gallardo HF, Doubrovin M, Doubrovina E, Finn R, et al. [131I]FIAU labeling of genetically transduced, tumor-reactive lymphocytes: cell-level dosimetry and dosedependent toxicity. Eur J Nucl Med Mol Imaging. 2006; 33: 988–997.
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , pp. 988-997
    • Zanzonico, P.1    Koehne, G.2    Gallardo, H.F.3    Doubrovin, M.4    Doubrovina, E.5    Finn, R.6
  • 35
    • 39549086787 scopus 로고    scopus 로고
    • Semiautomated radiosynthesis and biological evaluation of [18F]FEAU: A novel PET imaging agent for HSV1-tk/sr39tk reporter gene expression
    • Chin FT, Namavari M, Levi J, Subbarayan M, Ray P, chen X, et al. Semiautomated radiosynthesis and biological evaluation of [18F]FEAU: a novel PET imaging agent for HSV1-tk/sr39tk reporter gene expression. Mol Imaging Biol. 2008; 10: 82–91.
    • (2008) Mol Imaging Biol , vol.10 , pp. 82-91
    • Chin, F.T.1    Namavari, M.2    Levi, J.3    Subbarayan, M.4    Ray, P.5    Chen, X.6
  • 36
    • 34248529804 scopus 로고    scopus 로고
    • Biodistribution, PET, and radiation dosimetry estimates of HSV1-tk gene expression imaging agent 1-(2'-deoxy-2'-18Ffluoro- ?-D-arabinofuranosyl_-5-iodouracil in normal dogs
    • Nimmagadda S, Mangner TJ, Douglas KA, Muzik O, Shields AF. Biodistribution, PET, and radiation dosimetry estimates of HSV1-tk gene expression imaging agent 1-2'-deoxy-2'-18Ffluoro- ?-D-arabinofuranosyl_-5-iodouracil in normal dogs. J Nucl Med. 2007; 48: 655–660.
    • (2007) J Nucl Med , vol.48 , pp. 655-660
    • Nimmagadda, S.1    Mangner, T.J.2    Douglas, K.A.3    Muzik, O.4    Shields, A.F.5
  • 37
    • 37849009406 scopus 로고    scopus 로고
    • Syntheis and evaluation of cis-1-[4-(Hydroxymethyl)-2-cyclopenten-1-yl]5-[124I]iodouracil: A potential PET imaging agent foe HSV1-tk expression
    • Ahn H, Choi TH, De Castro K, Lee KC, Kim B, Moon BS, et al. Syntheis and evaluation of cis-1-[4-(hydroxymethyl)-2-cyclopenten-1-yl]5-[124I]iodouracil: a potential PET imaging agent foe HSV1-tk expression. J Med Chem. 2007; 50: 6032–6028.
    • (2007) J Med Chem , vol.50 , pp. 6028-6032
    • Ahn, H.1    Choi, T.H.2    De Castro, K.3    Lee, K.C.4    Kim, B.5    Moon, B.S.6
  • 38
    • 52449126958 scopus 로고    scopus 로고
    • Synthesis and in vitro evaluation of 5-[18F]fluoroalkyl pyrimidine nucleosides for molecular imaging of Herpes Simplex virus type 1 thymidine kinase reporter gene expression
    • Chacko A, Qu W, Kung HF. Synthesis and in vitro evaluation of 5-[18F]fluoroalkyl pyrimidine nucleosides for molecular imaging of Herpes Simplex virus type 1 thymidine kinase reporter gene expression. J Med Chem. 2008; 51: 5690–5701.
    • (2008) J Med Chem , vol.51 , pp. 5690-5701
    • Chacko, A.1    Qu, W.2    Kung, H.F.3
  • 39
    • 33645578117 scopus 로고    scopus 로고
    • Synthesis and characterization of a C(6) nucleoside analogue for the in vivo imaging of the gene expression of Herpes Simplex virus type-1 thymidine kinase
    • Johayem A, Raic-Malic S, Lazzati K, Schubiger PA, Scapozza L, Ametamey SM. Synthesis and characterization of a C(6) nucleoside analogue for the in vivo imaging of the gene expression of Herpes Simplex virus type-1 thymidine kinase. Chemistry and Biodiversity. 2006; 3: 274–282.
    • (2006) Chemistry and Biodiversity , vol.3 , pp. 274-282
    • Johayem, A.1    Raic-Malic, S.2    Lazzati, K.3    Schubiger, P.A.4    Scapozza, L.5    Ametamey, S.M.6
  • 41
    • 20444466384 scopus 로고    scopus 로고
    • Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients
    • Penuelas I, Mazzolini G, Boan JF, Sangro B, Marti-Climent J, Ruiz M, et al. Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients. Gastroenterology. 2005; 128: 1787–1795.
    • (2005) Gastroenterology , vol.128 , pp. 1787-1795
    • Penuelas, I.1    Mazzolini, G.2    Boan, J.F.3    Sangro, B.4    Marti-Climent, J.5    Ruiz, M.6
  • 42
    • 14644408765 scopus 로고    scopus 로고
    • Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography
    • Yaghoubi SS, Barrio JR, Namavari M, Satyamurthy N, Phelps ME, Herschman HR, et al. Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography. Cancer Gene Ther. 2005; 12: 329–339.
    • (2005) Cancer Gene Ther , vol.12 , pp. 329-339
    • Yaghoubi, S.S.1    Barrio, J.R.2    Namavari, M.3    Satyamurthy, N.4    Phelps, M.E.5    Herschman, H.R.6
  • 43
    • 37549025341 scopus 로고    scopus 로고
    • Multimodality imaging of T-cell hybridoma trafficking in collagen-induced arthritic mice: Image-based estimation of the number of cells accumulating in mouse paws
    • Yaghoubi SS, Creusot RJ, Ray P, Fathman CG, Gambhir SS. Multimodality imaging of T-cell hybridoma trafficking in collagen-induced arthritic mice: image-based estimation of the number of cells accumulating in mouse paws. Journal of Biomedical Optics. 2007; 12: 064025_1–11.
    • (2007) Journal of Biomedical Optics , vol.12 , pp. 1-11
    • Yaghoubi, S.S.1    Creusot, R.J.2    Ray, P.3    Fathman, C.G.4    Gambhir, S.S.5
  • 45
    • 0034785946 scopus 로고    scopus 로고
    • Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors
    • Yaghoubi SS, Wu L, Liang Q, Toyokuni T, Barrio JR, Namavari M, et al. Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors. Gene Ther. 2001; 8: 1072–1080.
    • (2001) Gene Ther , vol.8 , pp. 1072-1080
    • Yaghoubi, S.S.1    Wu, L.2    Liang, Q.3    Toyokuni, T.4    Barrio, J.R.5    Namavari, M.6
  • 46
    • 66149127014 scopus 로고    scopus 로고
    • Titration of variant HSV1-tk gene expression to determine the sensitivity of 18F-FHBG PET imaging in a prostate tumor
    • Johnson M, Karanikolas BD, Priceman SJ, Powell R, Black ME, Wu HM, et al. Titration of variant HSV1-tk gene expression to determine the sensitivity of 18F-FHBG PET imaging in a prostate tumor. J Nucl Med. 2009; 50: 757–764.
    • (2009) J Nucl Med , vol.50 , pp. 757-764
    • Johnson, M.1    Karanikolas, B.D.2    Priceman, S.J.3    Powell, R.4    Black, M.E.5    Wu, H.M.6
  • 47
    • 57349101092 scopus 로고    scopus 로고
    • Comparison between adenoviral and retroviral vectors for the transduction of the thymidine kinase PET reporter gene in rat mesenchymal stem cells
    • Roelants V, Labar D, de Meester C, Havaux X, Tabilio A, Gambhir SS, et al. Comparison between adenoviral and retroviral vectors for the transduction of the thymidine kinase PET reporter gene in rat mesenchymal stem cells. J Nucl Med. 2008; 49: 1836–1844.
    • (2008) J Nucl Med , vol.49 , pp. 1836-1844
    • Roelants, V.1    Labar, D.2    De Meester, C.3    Havaux, X.4    Tabilio, A.5    Gambhir, S.S.6
  • 48
    • 34248136542 scopus 로고    scopus 로고
    • Positron emission tomography of herpes simplex virus 1 oncolysis
    • Kuruppu D, Brownell AL, Zhu A, Yu M, Wang X, Kulu Y, et al. Positron emission tomography of herpes simplex virus 1 oncolysis. Cancer Res. 2007; 67: 3295–3300.
    • (2007) Cancer Res , vol.67 , pp. 3295-3300
    • Kuruppu, D.1    Brownell, A.L.2    Zhu, A.3    Yu, M.4    Wang, X.5    Kulu, Y.6
  • 49
    • 33846432737 scopus 로고    scopus 로고
    • Second-generation triple reporter for bioluminescence, micro-positron emission tomography, and fluorescence imaging
    • Kesarwala AH, Prior JL, Sun J, Harpstrite SE, Sharma V, Piwnica-Worms D. Second-generation triple reporter for bioluminescence, micro-positron emission tomography, and fluorescence imaging. Mol Imaging. 2006; 5: 465–474.
    • (2006) Mol Imaging , vol.5 , pp. 465-474
    • Kesarwala, A.H.1    Prior, J.L.2    Sun, J.3    Harpstrite, S.E.4    Sharma, V.5    Piwnica-Worms, D.6
  • 51
    • 0037076289 scopus 로고    scopus 로고
    • Noninvasive imaging of protein-protein interactions in living animals
    • Luker GD, Sharma V, Pica CM, Dahlheimer JL, Li W, Ochesky J, et al. Noninvasive imaging of protein-protein interactions in living animals. PNAS. 2002; 99: 6961–6966.
    • (2002) PNAS , vol.99 , pp. 6961-6966
    • Luker, G.D.1    Sharma, V.2    Pica, C.M.3    Dahlheimer, J.L.4    Li, W.5    Ochesky, J.6
  • 52
    • 0344897661 scopus 로고    scopus 로고
    • Imaging the spatial distribution of transgene expression in the lungs with positron emission tomography
    • Richard J-C, Factor P, Welch LC, Schuster DP. Imaging the spatial distribution of transgene expression in the lungs with positron emission tomography. Gene Ther. 2003; 10: 2074–2080.
    • (2003) Gene Ther , vol.10 , pp. 2074-2080
    • Richard, J.-C.1    Factor, P.2    Welch, L.C.3    Schuster, D.P.4
  • 54
    • 34250155318 scopus 로고    scopus 로고
    • Positron emission tomography imaging of conditional gene activation in the heart
    • Chang GY, Cao F, Krishnan M, Huang M, Li Z, Xie X, et al. Positron emission tomography imaging of conditional gene activation in the heart. J Mol Cell Cardiol. 2007; 43: 18–26.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 18-26
    • Chang, G.Y.1    Cao, F.2    Krishnan, M.3    Huang, M.4    Li, Z.5    Xie, X.6
  • 55
    • 33645079671 scopus 로고    scopus 로고
    • In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery
    • Cao F, Lin S, Xie X, Ray P, Patel M, Zhang X, et al. In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation. 2006; 113: 1005–1014.
    • (2006) Circulation , vol.113 , pp. 1005-1014
    • Cao, F.1    Lin, S.2    Xie, X.3    Ray, P.4    Patel, M.5    Zhang, X.6
  • 56
    • 1642329864 scopus 로고    scopus 로고
    • Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vectormediated gene delivery
    • Chen IY, Wu JC, Min J, Sundaresan G, Lewis X, Liang Q, et al. Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vectormediated gene delivery. Circulation. 2004; 109: 1415–1420.
    • (2004) Circulation , vol.109 , pp. 1415-1420
    • Chen, I.Y.1    Wu, J.C.2    Min, J.3    Sundaresan, G.4    Lewis, X.5    Liang, Q.6
  • 57
    • 34047218964 scopus 로고    scopus 로고
    • Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, smallanimal CT, and bioluminescence imaging
    • Deroose CM, De A, Loening AM, Chow PL, Ray P, Chatziioannou AF, et al. Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, smallanimal CT, and bioluminescence imaging. J Nucl Med. 2007; 48: 295–303.
    • (2007) J Nucl Med , vol.48 , pp. 295-303
    • Deroose, C.M.1    De, A.2    Loening, A.M.3    Chow, P.L.4    Ray, P.5    Chatziioannou, A.F.6
  • 58
    • 0036211595 scopus 로고    scopus 로고
    • Indirect monitoring of endogenous gene expression by positron emission tomography (PET) imaging of reporter gene expression in transgenic mice
    • Green LA, Yap C, Nguyen KN, Barrio JR, Namavari M, Satyamurthy N, et al. Indirect monitoring of endogenous gene expression by positron emission tomography (PET) imaging of reporter gene expression in transgenic mice. Mol Imaging Biol. 2002; 4: 71–81.
    • (2002) Mol Imaging Biol , vol.4 , pp. 71-81
    • Green, L.A.1    Yap, C.2    Nguyen, K.N.3    Barrio, J.R.4    Namavari, M.5    Satyamurthy, N.6
  • 59
    • 33845532052 scopus 로고    scopus 로고
    • Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival
    • Kim S, Doudet DJ, Studenov AR, Nian C, Ruth TJ, Gambhir SS, et al. Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival. Nat Med. 2006; 12: 1423–1428.
    • (2006) Nat Med , vol.12 , pp. 1423-1428
    • Kim, S.1    Doudet, D.J.2    Studenov, A.R.3    Nian, C.4    Ruth, T.J.5    Gambhir, S.S.6
  • 60
    • 0036665466 scopus 로고    scopus 로고
    • Noninvasive, rePETitive, quantitative measurement of gene expression from a bicistronic message by positron emission tomography, following gene transfer with adenovirus
    • Liang Q, Gotts J, Satyamurthy N, Barrio JR, Phelps ME, Gambhir SS, et al. Noninvasive, rePETitive, quantitative measurement of gene expression from a bicistronic message by positron emission tomography, following gene transfer with adenovirus. Mol Ther. 2002; 6: 73–82.
    • (2002) Mol Ther , vol.6 , pp. 73-82
    • Liang, Q.1    Gotts, J.2    Satyamurthy, N.3    Barrio, J.R.4    Phelps, M.E.5    Gambhir, S.S.6
  • 61
    • 0036717714 scopus 로고    scopus 로고
    • CL1-SR39: A noninvasive molecular imaging model of prostate cancer suicide gene therapy using positron emission tomography
    • Pantuck AJ, Berger F, Zisman A, Nguyen D, Tso CL, Matherly J, et al. CL1-SR39: a noninvasive molecular imaging model of prostate cancer suicide gene therapy using positron emission tomography. J Urol. 2002; 168: 1193–1198.
    • (2002) J Urol , vol.168 , pp. 1193-1198
    • Pantuck, A.J.1    Berger, F.2    Zisman, A.3    Nguyen, D.4    Tso, C.L.5    Matherly, J.6
  • 62
    • 0036252491 scopus 로고    scopus 로고
    • Optimizing prostate cancer suicide gene therapy using herpes simplex virus thymidine kinase active site variants
    • Pantuck AJ, Matherly J, Zisman A, Nguyen D, Berger F, Gambhir SS, et al. Optimizing prostate cancer suicide gene therapy using herpes simplex virus thymidine kinase active site variants. Hum Gene Ther. 2002; 13: 777–789.
    • (2002) Hum Gene Ther , vol.13 , pp. 777-789
    • Pantuck, A.J.1    Matherly, J.2    Zisman, A.3    Nguyen, D.4    Berger, F.5    Gambhir, S.S.6
  • 63
    • 1842429022 scopus 로고    scopus 로고
    • MicroPET imaging of Cre-loxP-mediated conditional activation of a herpes simplex virus type 1 thymidine kinase reporter gene
    • Sundaresan G, Paulmurugan R, Berger F, Stiles B, Nagayama Y, Wu H, et al. MicroPET imaging of Cre-loxP-mediated conditional activation of a herpes simplex virus type 1 thymidine kinase reporter gene. Gene Ther. 2004; 11: 609–618.
    • (2004) Gene Ther , vol.11 , pp. 609-618
    • Sundaresan, G.1    Paulmurugan, R.2    Berger, F.3    Stiles, B.4    Nagayama, Y.5    Wu, H.6
  • 64
    • 20844440770 scopus 로고    scopus 로고
    • Noninvasive imaging of ex vivo intracoronarily delivered nonviral therapeutic transgene expression in heart
    • Sen L, Gambhir SS, Furukawa H, Stout DB, Lam AL, Laks H, et al. Noninvasive imaging of ex vivo intracoronarily delivered nonviral therapeutic transgene expression in heart. Mol Ther. 2005; 12: 49–57.
    • (2005) Mol Ther , vol.12 , pp. 49-57
    • Sen, L.1    Gambhir, S.S.2    Furukawa, H.3    Stout, D.B.4    Lam, A.L.5    Laks, H.6
  • 65
    • 0344951190 scopus 로고    scopus 로고
    • MicroPET imaging of prostate cancer in LNCaP-sr39tk-gfp mouse xenografts
    • Yang H, Berger F, Tran C, Gambhir SS, Sawyers CL. MicroPET imaging of prostate cancer in LNCaP-sr39tk-gfp mouse xenografts. The Prostate. 2003; 55: 39–47.
    • (2003) The Prostate , vol.55 , pp. 39-47
    • Yang, H.1    Berger, F.2    Tran, C.3    Gambhir, S.S.4    Sawyers, C.L.5
  • 66
    • 0037047039 scopus 로고    scopus 로고
    • Positron emission tomog-raphy imaging of cardiac reporter gene expression in living rats
    • Wu JC, Inubushi M, Sundaresan G, Schelbert HR, Gambhir SS. Positron emission tomog-raphy imaging of cardiac reporter gene expression in living rats. Circulation. 2002; 106: 180–183.
    • (2002) Circulation , vol.106 , pp. 180-183
    • Wu, J.C.1    Inubushi, M.2    Sundaresan, G.3    Schelbert, H.R.4    Gambhir, S.S.5
  • 67
    • 33746781077 scopus 로고    scopus 로고
    • Imaging chemically modified adenovirus for targeting tumors expressing integrin avß3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene
    • Xiong Z, Cheng Z, Zhang X, Patel M, Wu JC, Gambhir SS, et al. Imaging chemically modified adenovirus for targeting tumors expressing integrin avß3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene. J Nucl Med. 2006; 47: 130–139.
    • (2006) J Nucl Med , vol.47 , pp. 130-139
    • Xiong, Z.1    Cheng, Z.2    Zhang, X.3    Patel, M.4    Wu, J.C.5    Gambhir, S.S.6
  • 68
    • 19644398835 scopus 로고    scopus 로고
    • Noninvasive monitoring of target gene expression by imaging reporter gene expression in living animals using improved bicistronic vectors
    • Wang Y, Iyer M, Annala AJ, Chappell S, Mauro V, Gambhir SS. Noninvasive monitoring of target gene expression by imaging reporter gene expression in living animals using improved bicistronic vectors. J Nucl Med. 2005; 46: 667–674.
    • (2005) J Nucl Med , vol.46 , pp. 667-674
    • Wang, Y.1    Iyer, M.2    Annala, A.J.3    Chappell, S.4    Mauro, V.5    Gambhir, S.S.6
  • 69
    • 4043081927 scopus 로고    scopus 로고
    • Molecular Imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium
    • Wu JC, Chen IY, Wang Y, Tseng JR, Chhabra A, Salek M, et al. Molecular Imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium. Circulation. 2004; 110: 685–691.
    • (2004) Circulation , vol.110 , pp. 685-691
    • Wu, J.C.1    Chen, I.Y.2    Wang, Y.3    Tseng, J.R.4    Chhabra, A.5    Salek, M.6
  • 70
    • 0141653938 scopus 로고    scopus 로고
    • Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography
    • Wu JC, chen IY, Sundaresan G, Min J, De A, Qiao J, et al. Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation. 2003; 108: 1302–1305.
    • (2003) Circulation , vol.108 , pp. 1302-1305
    • Wu, J.C.1    Chen, I.Y.2    Sundaresan, G.3    Min, J.4    De, A.5    Qiao, J.6
  • 71
    • 1242338786 scopus 로고    scopus 로고
    • Imaging tri-fusion multimodality reporter gene expression in living subjects
    • Ray P, De A, Min J, Tsien RY, Gambhir SS. Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res. 2004; 64: 1323–1330.
    • (2004) Cancer Res , vol.64 , pp. 1323-1330
    • Ray, P.1    De, A.2    Min, J.3    Tsien, R.Y.4    Gambhir, S.S.5
  • 72
    • 34248169598 scopus 로고    scopus 로고
    • Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects
    • Ray P, Tsien R, Gambhir SS. Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects. Cancer Res. 2007; 67: 3085–3093.
    • (2007) Cancer Res , vol.67 , pp. 3085-3093
    • Ray, P.1    Tsien, R.2    Gambhir, S.S.3
  • 73
    • 0037444158 scopus 로고    scopus 로고
    • Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice
    • Ray P, Wu AM, Gambhir SS. Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice. Cancer Res. 2003; 63: 1160–1165.
    • (2003) Cancer Res , vol.63 , pp. 1160-1165
    • Ray, P.1    Wu, A.M.2    Gambhir, S.S.3
  • 74
    • 34548077489 scopus 로고    scopus 로고
    • Replication-comPETent adenovirus-mediated suicide gene therapy with radiation in a preclinical model of pancreatic cancer
    • Freytag SO, Barton KN, Brown SL, Narra V, Zhang Y, Tyson D, et al. Replication-comPETent adenovirus-mediated suicide gene therapy with radiation in a preclinical model of pancreatic cancer. Mol Ther. 2007; 15: 1600–1606.
    • (2007) Mol Ther , vol.15 , pp. 1600-1606
    • Freytag, S.O.1    Barton, K.N.2    Brown, S.L.3    Narra, V.4    Zhang, Y.5    Tyson, D.6
  • 75
    • 11144307071 scopus 로고    scopus 로고
    • Coexpression of herpesviral thymidine kinase reporter gene and VEGF gene for noninvasive monitoring of therapeutic gene transfer: An in vitro evaluation
    • Anton M, Wittermann C, Haubner R, Simoes M, Reder S, Essien B, et al. Coexpression of herpesviral thymidine kinase reporter gene and VEGF gene for noninvasive monitoring of therapeutic gene transfer: an in vitro evaluation J Nucl Med. 2004; 45: 1743–1746.
    • (2004) J Nucl Med , vol.45 , pp. 1743-1746
    • Anton, M.1    Wittermann, C.2    Haubner, R.3    Simoes, M.4    Reder, S.5    Essien, B.6
  • 76
    • 33845788246 scopus 로고    scopus 로고
    • Fetal gene transfer using lentiviral vectors: In vivo detection of gene expression by microPET and optical imaging in fetal and infant monkeys
    • Tarantal AF, Lee CCI, Jimenez DF, Cherry SR. Fetal gene transfer using lentiviral vectors: in vivo detection of gene expression by microPET and optical imaging in fetal and infant monkeys. Hum Gene Ther. 2006; 17: 1254–1261.
    • (2006) Hum Gene Ther , vol.17 , pp. 1254-1261
    • Tarantal, A.F.1    Lee, C.2    Jimenez, D.F.3    Cherry, S.R.4
  • 77
    • 49149086250 scopus 로고    scopus 로고
    • Adenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer
    • Burton JB, Johnson M, Sato M, Koh SBS, Mulholland DJ, Stout D, et al. Adenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer. Nat Med. 2008; 14: 882–888.
    • (2008) Nat Med , vol.14 , pp. 882-888
    • Burton, J.B.1    Johnson, M.2    Sato, M.3    Koh, S.4    Mulholland, D.J.5    Stout, D.6
  • 78
    • 33646058046 scopus 로고    scopus 로고
    • Monitoring the antitumor response of naive and memory CD8 T cells in RAG1-/- mice by positron-emission tomography
    • Su H, Chang DS, Gambhir SS, Braun J. Monitoring the antitumor response of naive and memory CD8 T cells in RAG1-/- mice by positron-emission tomography. J Immunol. 2006; 176: 4459–4467
    • (2006) J Immunol , vol.176 , pp. 4459-4467
    • Su, H.1    Chang, D.S.2    Gambhir, S.S.3    Braun, J.4
  • 79
    • 4544316108 scopus 로고    scopus 로고
    • Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene
    • Kim YJ, Dubey P, Ray P, Gambhir SS, Witte ON. Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene. Mol Imaging Biol. 2004; 6: 331–340.
    • (2004) Mol Imaging Biol , vol.6 , pp. 331-340
    • Kim, Y.J.1    Dubey, P.2    Ray, P.3    Gambhir, S.S.4    Witte, O.N.5
  • 80
    • 33746631642 scopus 로고    scopus 로고
    • Noninvasive imaging of islet grafts using positron-emission tomography
    • Lu Y, Dang H, Middleton B, Zhang Z, Washburn L, Stout DB, et al. Noninvasive imaging of islet grafts using positron-emission tomography. PNAS. 2006; 103: 11294–11299.
    • (2006) PNAS , vol.103 , pp. 11294-11299
    • Lu, Y.1    Dang, H.2    Middleton, B.3    Zhang, Z.4    Washburn, L.5    Stout, D.B.6
  • 81
    • 2942652709 scopus 로고    scopus 로고
    • Quantitation of cell number by a positron emission tomography reporter gene strategy
    • Su H, Forbes A, Gambhir SS, Braun J. Quantitation of cell number by a positron emission tomography reporter gene strategy. Mol Imaging Biol. 2004; 6: 139–148.
    • (2004) Mol Imaging Biol , vol.6 , pp. 139-148
    • Su, H.1    Forbes, A.2    Gambhir, S.S.3    Braun, J.4
  • 82
    • 28444432657 scopus 로고    scopus 로고
    • Visualization of a primary antitumor immune response by positron emission tomography
    • Shu CJ, Guo S, Kim YJ, Shelly SM, Nijagal A, Ray P, et al. Visualization of a primary antitumor immune response by positron emission tomography. PNAS. 2005; 102: 17412–17417.
    • (2005) PNAS , vol.102 , pp. 17412-17417
    • Shu, C.J.1    Guo, S.2    Kim, Y.J.3    Shelly, S.M.4    Nijagal, A.5    Ray, P.6
  • 83
    • 0037418009 scopus 로고    scopus 로고
    • Quantitative imaging of T cell antitumor response by positron-emission tomography
    • Dubey P, Su H, Adonai N, Du S, Rosato A, Braun J, et al. Quantitative imaging of T cell antitumor response by positron-emission tomography. PNAS. 2003; 100: 1232–1237.
    • (2003) PNAS , vol.100 , pp. 1232-1237
    • Dubey, P.1    Su, H.2    Adonai, N.3    Du, S.4    Rosato, A.5    Braun, J.6
  • 84
    • 34247385404 scopus 로고    scopus 로고
    • Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation
    • Cao F, Drukker M, Lin S, Sheikh A, Xie X, Li Z, et al. Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation. Cloning and Stem Cells. 2007; 9: 107–117.
    • (2007) Cloning and Stem Cells , vol.9 , pp. 107-117
    • Cao, F.1    Drukker, M.2    Lin, S.3    Sheikh, A.4    Xie, X.5    Li, Z.6
  • 85
    • 9544242826 scopus 로고    scopus 로고
    • Noninvasive imaging of Herpes Simplex virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy
    • Tjuvajev JG, Finn R, Watanabe K, Joshi R, Oku T, Kennedy J, et al. Noninvasive imaging of Herpes Simplex virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res. 1996; 56: 4087–4095.
    • (1996) Cancer Res , vol.56 , pp. 4087-4095
    • Tjuvajev, J.G.1    Finn, R.2    Watanabe, K.3    Joshi, R.4    Oku, T.5    Kennedy, J.6
  • 86
    • 62849100440 scopus 로고    scopus 로고
    • Imaging of lymph node micrometastases using an oncolytic herpes virus and [18F]FEAU PET
    • Brader P, Kelly K, Gang S, Shah JP, Wong RJ, Hricak H, et al. Imaging of lymph node micrometastases using an oncolytic herpes virus and [18F]FEAU PET. PLOS ONE. 2009; 4: e4789.
    • (2009) PLOS ONE , vol.4789 , pp. 4
    • Brader, P.1    Kelly, K.2    Gang, S.3    Shah, J.P.4    Wong, R.J.5    Hricak, H.6
  • 87
    • 0034924079 scopus 로고    scopus 로고
    • Positron emission tomography imaging for herpes virus infection: Implications for oncolytic viral treatments of cancer
    • Bennett JJ, Tjuvajev J, Johnson P, Doubrovin M, Akhurst T, Malholtra S, et al. Positron emission tomography imaging for herpes virus infection: implications for oncolytic viral treatments of cancer. Nat Med. 2001; 7: 859–863.
    • (2001) Nat Med , vol.7 , pp. 859-863
    • Bennett, J.J.1    Tjuvajev, J.2    Johnson, P.3    Doubrovin, M.4    Akhurst, T.5    Malholtra, S.6
  • 88
    • 0035300468 scopus 로고    scopus 로고
    • Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic Herpes Simplex virus type 1 mutant vectors in vivo
    • Jacobs A, Tjuvajev JG, Dubrovin M, Akhurst T, Balatoni J, Beattie B, et al. Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic Herpes Simplex virus type 1 mutant vectors in vivo. Cancer Res. 2001; 61: 2983–2995.
    • (2001) Cancer Res , vol.61 , pp. 2983-2995
    • Jacobs, A.1    Tjuvajev, J.G.2    Dubrovin, M.3    Akhurst, T.4    Balatoni, J.5    Beattie, B.6
  • 90
    • 0035979208 scopus 로고    scopus 로고
    • Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo
    • Doubrovin M, Ponomarev V, Beresten T, Balatoni J, Bornmann W, Finn R, et al. Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo. PNAS. 2001; 98: 9300–9305.
    • (2001) PNAS , vol.98 , pp. 9300-9305
    • Doubrovin, M.1    Ponomarev, V.2    Beresten, T.3    Balatoni, J.4    Bornmann, W.5    Finn, R.6
  • 91
    • 54249165055 scopus 로고    scopus 로고
    • Noninvasive molecular imaging of hypoxia in human xenografts: Comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers
    • Fuqiu H, Deng X, Wen B, Liu Y, Sun X, Xing L, et al. Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers. Cancer Res. 2008; 68: 8597–8606.
    • (2008) Cancer Res , vol.68 , pp. 8597-8606
    • Fuqiu, H.1    Deng, X.2    Wen, B.3    Liu, Y.4    Sun, X.5    Xing, L.6
  • 92
    • 0033205584 scopus 로고    scopus 로고
    • A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase
    • Tjuvajev JG, Joshi A, Callegari J, Lindsley L, Joshi R, Balatoni J, et al. A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase. Neoplasia. 1999; 1: 315–320.
    • (1999) Neoplasia , vol.1 , pp. 315-320
    • Tjuvajev, J.G.1    Joshi, A.2    Callegari, J.3    Lindsley, L.4    Joshi, R.5    Balatoni, J.6
  • 93
    • 0035448565 scopus 로고    scopus 로고
    • Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas
    • Jacobs A, Voges J, Reszka R, Lercher M, Grossmann A, Kracht L, et al. Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas. Lancet. 2001; 358: 727–729.
    • (2001) Lancet , vol.358 , pp. 727-729
    • Jacobs, A.1    Voges, J.2    Reszka, R.3    Lercher, M.4    Grossmann, A.5    Kracht, L.6
  • 94
    • 33748110630 scopus 로고    scopus 로고
    • Assessment of 123I-FIAU imaging of herpes simplex viral gene expression in the treatment of glioma
    • Dempsey MF, Wyper D, Owens J, Pimlott S, Papanastassiou V, Patterson J, et al. Assessment of 123I-FIAU imaging of herpes simplex viral gene expression in the treatment of glioma. Nucl Med Commun. 2006; 27: 611–617.
    • (2006) Nucl Med Commun , vol.27 , pp. 611-617
    • Dempsey, M.F.1    Wyper, D.2    Owens, J.3    Pimlott, S.4    Papanastassiou, V.5    Patterson, J.6
  • 95
    • 1642512319 scopus 로고    scopus 로고
    • Non-invasive in vivo imaging with radiolabelled FIAU for monitoring cancer gene therapy using herpes simplex virus type 1 thymidine kinase and ganciclovir
    • Deng W, Yang WK, Lai W, Liu R, Hwang J, Yang D, et al. Non-invasive in vivo imaging with radiolabelled FIAU for monitoring cancer gene therapy using herpes simplex virus type 1 thymidine kinase and ganciclovir. Eur J Nucl Med Mol Imaging. 2004; 31: 99–109.
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 99-109
    • Deng, W.1    Yang, W.K.2    Lai, W.3    Liu, R.4    Hwang, J.5    Yang, D.6
  • 97
    • 33745552227 scopus 로고    scopus 로고
    • Serial in vivo imaging of lung metastases model and gene therapy using HSV1-tk and Ganciclovir
    • Deng W, Wu C, Lee C, Yang WK, Wang H, Liu R, et al. Serial in vivo imaging of lung metastases model and gene therapy using HSV1-tk and Ganciclovir. J Nucl Med. 2006; 47: 877–884.
    • (2006) J Nucl Med , vol.47 , pp. 877-884
    • Deng, W.1    Wu, C.2    Lee, C.3    Yang, W.K.4    Wang, H.5    Liu, R.6
  • 98
    • 33747125144 scopus 로고    scopus 로고
    • Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring Herpes Simplex virus type 1 thymidine kinase and Ganciclovir prodrug activation gene therapy of cancer
    • Wang H, Yu H, Liu R, Lin M, Gelovani JG, Hwang J, et al. Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring Herpes Simplex virus type 1 thymidine kinase and Ganciclovir prodrug activation gene therapy of cancer. J Nucl Med. 2006; 47: 1161–1171.
    • (2006) J Nucl Med , vol.47 , pp. 1161-1171
    • Wang, H.1    Yu, H.2    Liu, R.3    Lin, M.4    Gelovani, J.G.5    Hwang, J.6
  • 99
    • 12244310130 scopus 로고    scopus 로고
    • Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes
    • Koehne G, Doubrovin M, Doubrovina E, Zanzonico P, Gallardo HF, Ivanova A, et al. Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes. Nat Biotechnol. 2003; 21: 405–413.
    • (2003) Nat Biotechnol , vol.21 , pp. 405-413
    • Koehne, G.1    Doubrovin, M.2    Doubrovina, E.3    Zanzonico, P.4    Gallardo, H.F.5    Ivanova, A.6
  • 100
    • 46749106001 scopus 로고    scopus 로고
    • Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging
    • Dobrenkov K, Olszewska M, Likar Y, Shenker L, Gunset G, Cai S, et al. Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging. J Nucl Med. 2008; 49: 1162–1170.
    • (2008) J Nucl Med , vol.49 , pp. 1162-1170
    • Dobrenkov, K.1    Olszewska, M.2    Likar, Y.3    Shenker, L.4    Gunset, G.5    Cai, S.6
  • 101
    • 37649007920 scopus 로고    scopus 로고
    • Imaging of gene expression in live pancreatic islet cell lines using dual-isotope SPECT
    • Tai JH, Nguyen B, Wells RG, Kovacs MS, McGirr R, Prato FS, et al. Imaging of gene expression in live pancreatic islet cell lines using dual-isotope SPECT. J Nucl Med. 2008; 49: 94–102.
    • (2008) J Nucl Med , vol.49 , pp. 94-102
    • Tai, J.H.1    Nguyen, B.2    Wells, R.G.3    Kovacs, M.S.4    McGirr, R.5    Prato, F.S.6
  • 102
    • 0035300565 scopus 로고    scopus 로고
    • Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing
    • Black ME, Kokoris MS, Sabo P. Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing. Cancer Res. 2001; 61: 3022–3026.
    • (2001) Cancer Res , vol.61 , pp. 3022-3026
    • Black, M.E.1    Kokoris, M.S.2    Sabo, P.3
  • 104
    • 16544372457 scopus 로고    scopus 로고
    • PET of cardiac transgene expression: Comparison of 2 approaches based on Herpesviral thymidine kinase reporter gene
    • Miyagawa M, Anton M, Haubner R, Simoes MV, Stadele C, Erhardt W, et al. PET of cardiac transgene expression: comparison of 2 approaches based on Herpesviral thymidine kinase reporter gene. J Nucl Med. 2004; 45: 1917–1923.
    • (2004) J Nucl Med , vol.45 , pp. 1917-1923
    • Miyagawa, M.1    Anton, M.2    Haubner, R.3    Simoes, M.V.4    Stadele, C.5    Erhardt, W.6
  • 105
    • 42049104749 scopus 로고    scopus 로고
    • Imaging of HSV-tk reporter gene expression: Comparison between [18F]FEAU, [18F]FFEAU, and other imaging probes
    • Miyagawa T, Gogiberidze G, Serganova I, Cai S, Balatoni JA, Thaler HT, et al. Imaging of HSV-tk reporter gene expression: comparison between [18F]FEAU, [18F]FFEAU, and other imaging probes. J Nucl Med. 2008; 49: 637–648.
    • (2008) J Nucl Med , vol.49 , pp. 637-648
    • Miyagawa, T.1    Gogiberidze, G.2    Serganova, I.3    Cai, S.4    Balatoni, J.A.5    Thaler, H.T.6
  • 107
    • 34250672869 scopus 로고    scopus 로고
    • A humanderived reporter gene for noninvasive imaging in humans: Mitochondrial thymidine kinase type 2
    • Ponomarev V, Doubrovin M, Shavrin A, Serganova I, Beresten T, Ageyeva L, et al. A humanderived reporter gene for noninvasive imaging in humans: mitochondrial thymidine kinase type 2. J Nucl Med. 2007; 48: 819–826.
    • (2007) J Nucl Med , vol.48 , pp. 819-826
    • Ponomarev, V.1    Doubrovin, M.2    Shavrin, A.3    Serganova, I.4    Beresten, T.5    Ageyeva, L.6
  • 108
    • 0029888564 scopus 로고    scopus 로고
    • Phosphorylation of the anti-hepatitis B nucleoside analog 1-(2'-deoxy-2'- fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) by human cytosolic and mitochondrial thymidine kinase and implications for cytotoxicity
    • Wang J, Eriksson S. Phosphorylation of the anti-hepatitis B nucleoside analog 1-(2'-deoxy-2'- fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) by human cytosolic and mitochondrial thymidine kinase and implications for cytotoxicity. Antimicrob Agents Chemother. 1996; 40: 1555–1557.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1555-1557
    • Wang, J.1    Eriksson, S.2
  • 109
    • 33847783726 scopus 로고    scopus 로고
    • Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging Varicella-Zoster virus thymidine kinase gene expression using positron emission tomography
    • Chitneni SK, Deroose CM, Balzarini J, Gijsbers R, Celen SJL, de Groot TJ, et al. Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging Varicella-Zoster virus thymidine kinase gene expression using positron emission tomography. J Med Chem. 2007; 50: 1041–1049.
    • (2007) J Med Chem , vol.50 , pp. 1041-1049
    • Chitneni, S.K.1    Deroose, C.M.2    Balzarini, J.3    Gijsbers, R.4    Celen, S.5    De Groot, T.J.6
  • 111
    • 34249716871 scopus 로고    scopus 로고
    • Developing MR reporter genes: Promises and pitfalls
    • Gilad AA, Winnard Jr PT, Van Zijl PCM, Bulte JWM. Developing MR reporter genes: promises and pitfalls. NMR Biomed. 2007; 20: 275–290.
    • (2007) NMR Biomed , vol.20 , pp. 275-290
    • Gilad, A.A.1    Winnard, P.T.2    Van Zijl, P.3    Bulte, J.4
  • 112
    • 67650080279 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of 11C-labeled Beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging
    • Celen S, Cleynhens J, Deroose C, De Groot T, Ibrahimi A, Gijsbers R, et al. Synthesis and biological evaluation of 11C-labeled Beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging. Bioorg Med Chem Lett. 2009; 17: 5117–5125.
    • (2009) Bioorg Med Chem Lett , vol.17 , pp. 5117-5125
    • Celen, S.1    Cleynhens, J.2    Deroose, C.3    De Groot, T.4    Ibrahimi, A.5    Gijsbers, R.6
  • 113
    • 6544233317 scopus 로고    scopus 로고
    • RePETitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals
    • MacLaren DC, Gambhir SS, Satyamurthy N, Barrio JR, Sharfstein S, Toyokuni T, et al. RePETitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals. Gene Ther. 1999; 6: 785–791.
    • (1999) Gene Ther , vol.6 , pp. 785-791
    • Maclaren, D.C.1    Gambhir, S.S.2    Satyamurthy, N.3    Barrio, J.R.4    Sharfstein, S.5    Toyokuni, T.6
  • 114
    • 0033827201 scopus 로고    scopus 로고
    • Quantification of target gene expression by imaging reporter gene expression in living animals
    • Yu Y, Annala AJ, Barrio JR, Toyokuni T, Satyamurthy N, Namavari M, et al. Quantification of target gene expression by imaging reporter gene expression in living animals. Nat Med. 2000; 6: 933–937.
    • (2000) Nat Med , vol.6 , pp. 933-937
    • Yu, Y.1    Annala, A.J.2    Barrio, J.R.3    Toyokuni, T.4    Satyamurthy, N.5    Namavari, M.6
  • 116
    • 0034772465 scopus 로고    scopus 로고
    • Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction
    • Liang Q, Satyamurthy N, Barrio JR, Toyokuni T, Phelps ME, Gambhir SS, et al. Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction. Gene Ther. 2001; 8: 1490–1498.
    • (2001) Gene Ther , vol.8 , pp. 1490-1498
    • Liang, Q.1    Satyamurthy, N.2    Barrio, J.R.3    Toyokuni, T.4    Phelps, M.E.5    Gambhir, S.S.6
  • 117
    • 34248531774 scopus 로고    scopus 로고
    • Development of a dual membrane protein reporter system using sodium iodide symporter and mutant dopamine D2 receptor transgenes
    • Hwang DW, Kang JH, Chang YS, Jeong JM, Chung J, Lee MC, et al. Development of a dual membrane protein reporter system using sodium iodide symporter and mutant dopamine D2 receptor transgenes. J Nucl Med. 2007; 48: 588–595.
    • (2007) J Nucl Med , vol.48 , pp. 588-595
    • Hwang, D.W.1    Kang, J.H.2    Chang, Y.S.3    Jeong, J.M.4    Chung, J.5    Lee, M.C.6
  • 118
    • 31844444853 scopus 로고    scopus 로고
    • Potential of the FES–hERL PET reporter gene system — Basic evaluation for gene therapy monitoring
    • Furukawa T, Lohith TG, Takamatsu S, Mori T, Tanaka T, Fujibayashi Y. Potential of the FES–hERL PET reporter gene system — Basic evaluation for gene therapy monitoring. Nucl Med Biol. 2006; 33: 145–151.
    • (2006) Nucl Med Biol , vol.33 , pp. 145-151
    • Furukawa, T.1    Lohith, T.G.2    Takamatsu, S.3    Mori, T.4    Tanaka, T.5    Fujibayashi, Y.6
  • 119
    • 49149132066 scopus 로고    scopus 로고
    • Basic evaluation of FES-hERL PET tracer-reporter gene system for in vivo monitoring of adenoviral-mediated gene therapy
    • Lohith TG, Furukawa T, Mori T, Kobayashi M, Fujibayashi Y. Basic evaluation of FES-hERL PET tracer-reporter gene system for in vivo monitoring of adenoviral-mediated gene therapy. Mol Imaging Biol. 2008; 10: 245–252.
    • (2008) Mol Imaging Biol , vol.10 , pp. 245-252
    • Lohith, T.G.1    Furukawa, T.2    Mori, T.3    Kobayashi, M.4    Fujibayashi, Y.5
  • 120
    • 0034759663 scopus 로고    scopus 로고
    • A noninvasive reporter system to image adenoviral-mediated gene transfer to ovarian cancer xenografts
    • Chaudhuri TR, Rogers BE, Buchsbaum DJ, Mountz JM, Zinn KR. A noninvasive reporter system to image adenoviral-mediated gene transfer to ovarian cancer xenografts. Gynecol Oncol. 2001; 83: 432–438.
    • (2001) Gynecol Oncol , vol.83 , pp. 432-438
    • Chaudhuri, T.R.1    Rogers, B.E.2    Buchsbaum, D.J.3    Mountz, J.M.4    Zinn, K.R.5
  • 122
    • 0034019279 scopus 로고    scopus 로고
    • Noninvasive monitoring of gene transfer using a reporter receptor imaged with a high-affinity peptide radiolabeled with 99mTc or 188Re
    • Zinn KR, Buchsbaum DJ, chaudhuri TR, Mountz JM, Grizzle WE, Rogers BE. Noninvasive monitoring of gene transfer using a reporter receptor imaged with a high-affinity peptide radiolabeled with 99mTc or 188Re. J Nucl Med. 2000; 41: 887–895.
    • (2000) J Nucl Med , vol.41 , pp. 887-895
    • Zinn, K.R.1    Buchsbaum, D.J.2    Chaudhuri, T.R.3    Mountz, J.M.4    Grizzle, W.E.5    Rogers, B.E.6
  • 123
    • 0037264051 scopus 로고    scopus 로고
    • Non-invasive gamma camera imaging of gene transfer using an adenoviral vector encoding an epitope-tagged receptor as a reporter
    • Rogers BE, chaudhuri TR, Reynolds PN, Manna DD, Zinn KR. Non-invasive gamma camera imaging of gene transfer using an adenoviral vector encoding an epitope-tagged receptor as a reporter. Gene Ther. 2003; 10: 105–114.
    • (2003) Gene Ther , vol.10 , pp. 105-114
    • Rogers, B.E.1    Chaudhuri, T.R.2    Reynolds, P.N.3    Manna, D.D.4    Zinn, K.R.5
  • 125
    • 57349114294 scopus 로고    scopus 로고
    • Engineered antibody fragments with infinite affinity as reporter genes for PET imaging
    • Wei LH, Olafsen T, Radu CG, Hildebrandt IJ, McCoy MR, Phelps ME, et al. Engineered antibody fragments with infinite affinity as reporter genes for PET imaging. J Nucl Med. 2008; 49: 1828–1835.
    • (2008) J Nucl Med , vol.49 , pp. 1828-1835
    • Wei, L.H.1    Olafsen, T.2    Radu, C.G.3    Hildebrandt, I.J.4    McCoy, M.R.5    Phelps, M.E.6
  • 126
    • 0036732003 scopus 로고    scopus 로고
    • Sodium iodide symporter: Its role in nuclear medicine
    • Chung J. Sodium iodide symporter: its role in nuclear medicine. J Nucl Med. 2002; 43: 1188–1200.
    • (2002) J Nucl Med , vol.43 , pp. 1188-1200
    • Chung, J.1
  • 128
    • 0036714719 scopus 로고    scopus 로고
    • In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas
    • Cho J-Y, Shen DHY, Yang W, Williams B, Buckwalter TLF, La Perle KMD, et al. In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas. Gene Ther. 2002; 9: 1139–1145.
    • (2002) Gene Ther , vol.9 , pp. 1139-1145
    • Cho, J.-Y.1    Shen, D.2    Yang, W.3    Williams, B.4    Buckwalter, T.5    La Perle, K.6
  • 129
    • 1342304015 scopus 로고    scopus 로고
    • A transporter gene (Sodium iodide symporter) for dual purposes in gene therapy: Imaging and therapy
    • Cho J-Y. A transporter gene (sodium iodide symporter) for dual purposes in gene therapy: imaging and therapy. Curr Gene Ther. 2002; 2: 393–402.
    • (2002) Curr Gene Ther , vol.2 , pp. 393-402
    • Cho, J.-Y.1
  • 130
    • 34948830701 scopus 로고    scopus 로고
    • Radioiodide imaging and radiovirotherapy of multiple myeloma using VSV(Delta51)-NIS, an attenuated vesicular stomatitis virus encoding the sodium iodide symporter gene
    • Goel A, Carlson SK, Classic KL, Greiner S, Naik S, Power AT, et al. Radioiodide imaging and radiovirotherapy of multiple myeloma using VSV(delta51)-NIS, an attenuated vesicular stomatitis virus encoding the sodium iodide symporter gene. Blood. 2007; 110: 2342–2350.
    • (2007) Blood , vol.110 , pp. 2342-2350
    • Goel, A.1    Carlson, S.K.2    Classic, K.L.3    Greiner, S.4    Naik, S.5    Power, A.T.6
  • 131
    • 1642525140 scopus 로고    scopus 로고
    • Quantitative imaging of Na/I symporter transgene expression using positron emission tomography in the living animal
    • Groot-Wassink T, Aboagye EO, Wang Y, Lemoine NR, Reader AJ, Vassaux G. Quantitative imaging of Na/I symporter transgene expression using positron emission tomography in the living animal. Mol Ther. 2004; 9: 436–442.
    • (2004) Mol Ther , vol.9 , pp. 436-442
    • Groot-Wassink, T.1    Aboagye, E.O.2    Wang, Y.3    Lemoine, N.R.4    Reader, A.J.5    Vassaux, G.6
  • 132
    • 1542318458 scopus 로고    scopus 로고
    • Feasibility of sodium/iodide symporter gene as a new imaging reporter gene: Comparison with HSV1-tk
    • Shin JH, chung J, Kang JH, Lee YJ, Kim K, Kim CW, et al. Feasibility of sodium/iodide symporter gene as a new imaging reporter gene: comparison with HSV1-tk. Eur J Nucl Med Mol Imaging. 2004; 31: 425–432.
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 425-432
    • Shin, J.H.1    Chung, J.2    Kang, J.H.3    Lee, Y.J.4    Kim, K.5    Kim, C.W.6
  • 133
    • 34247240603 scopus 로고    scopus 로고
    • Enhanced expression of adenovirusmediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment
    • Lim SJ, Paeng JC, Kim SJ, Kim SY, Lee H, Moon DH. Enhanced expression of adenovirusmediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment. J Nucl Med. 2007; 48: 398–404.
    • (2007) J Nucl Med , vol.48 , pp. 398-404
    • Lim, S.J.1    Paeng, J.C.2    Kim, S.J.3    Kim, S.Y.4    Lee, H.5    Moon, D.H.6
  • 134
    • 66249138868 scopus 로고    scopus 로고
    • Effects of theophylline on radioiodide uptake in MCF-7 breast cancer and NIS gene-transduced SNU-C5 colon cancer cells
    • Yoon J, Park B, Paik J, Jung K, Ko B, Lee K. Effects of theophylline on radioiodide uptake in MCF-7 breast cancer and NIS gene-transduced SNU-C5 colon cancer cells. Cancer Biotherapy and Radiopharmaceuticals. 2009; 24: 201–208.
    • (2009) Cancer Biotherapy and Radiopharmaceuticals , vol.24 , pp. 201-208
    • Yoon, J.1    Park, B.2    Paik, J.3    Jung, K.4    Ko, B.5    Lee, K.6
  • 138
    • 29444443670 scopus 로고    scopus 로고
    • Applications of molecular imaging in cancer gene therapy
    • Iyer M, Sato M, Johnson M, Gambhir SS, Wu L. Applications of molecular imaging in cancer gene therapy. Curr Gene Ther. 2005; 5: 607–618.
    • (2005) Curr Gene Ther , vol.5 , pp. 607-618
    • Iyer, M.1    Sato, M.2    Johnson, M.3    Gambhir, S.S.4    Wu, L.5
  • 143
    • 0033139768 scopus 로고    scopus 로고
    • Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: Implications for noninvasive imaging of transgene expression
    • Jacobs A, Dubrovin M, Hewett J, Sena-Esteves M, Tan CW, Slack M, et al. Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression. Neoplasia. 1999; 1: 154–161.
    • (1999) Neoplasia , vol.1 , pp. 154-161
    • Jacobs, A.1    Dubrovin, M.2    Hewett, J.3    Sena-Esteves, M.4    Tan, C.W.5    Slack, M.6
  • 144
    • 2442562277 scopus 로고    scopus 로고
    • A novel triplemodality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging
    • Ponomarev V, Doubrovin M, Serganova I, Vider J, Shavrin A, Beresten T, et al. A novel triplemodality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging. Eur J Nucl Med Mol Imaging. 2004; 31: 740–751.
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 740-751
    • Ponomarev, V.1    Doubrovin, M.2    Serganova, I.3    Vider, J.4    Shavrin, A.5    Beresten, T.6
  • 145
    • 25144519183 scopus 로고    scopus 로고
    • Viral oncolysis by herpes simplex virus and other viruses
    • Kuruppu D, Tanabe KK. Viral oncolysis by herpes simplex virus and other viruses. Cancer Biology and Therapy. 2005; 4: 524–531.
    • (2005) Cancer Biology and Therapy , vol.4 , pp. 524-531
    • Kuruppu, D.1    Tanabe, K.K.2
  • 146
    • 33947419410 scopus 로고    scopus 로고
    • Virus-associated tumor imaging by induction of viral gene expression
    • Fu D, Tanhehco YC, Chen J, Foss CA, Fox JJ, Lemas V, et al. Virus-associated tumor imaging by induction of viral gene expression. Clin Cancer Res. 2007; 13: 1453–1458.
    • (2007) Clin Cancer Res , vol.13 , pp. 1453-1458
    • Fu, D.1    Tanhehco, Y.C.2    Chen, J.3    Foss, C.A.4    Fox, J.J.5    Lemas, V.6
  • 147
    • 66649123890 scopus 로고    scopus 로고
    • Imaging a genetically engineered oncolytic vaccinia virus (GLV-1h99) using a human norepinephrine transporter reporter gene
    • Brader P, Kelly KJ, Chen N, Yu YA, Zhang Q, Zanzonico P, et al. Imaging a genetically engineered oncolytic vaccinia virus (GLV-1h99) using a human norepinephrine transporter reporter gene. Clin Cancer Res. 2009; 15: 3791–3801.
    • (2009) Clin Cancer Res , vol.15 , pp. 3791-3801
    • Brader, P.1    Kelly, K.J.2    Chen, N.3    Yu, Y.A.4    Zhang, Q.5    Zanzonico, P.6
  • 148
    • 36949007391 scopus 로고    scopus 로고
    • SPECT/CT imaging of oncolytic adenovirus propagation in tumours in vivo using the Na/I symporter as a reporter gene
    • Merron A, Peerlinck I, Martin-Duque P, Burnet J, Quintanilla M, Mather S, et al. SPECT/CT imaging of oncolytic adenovirus propagation in tumours in vivo using the Na/I symporter as a reporter gene. Gene Ther. 2007; 14: 1731–1738.
    • (2007) Gene Ther , vol.14 , pp. 1731-1738
    • Merron, A.1    Peerlinck, I.2    Martin-Duque, P.3    Burnet, J.4    Quintanilla, M.5    Mather, S.6
  • 149
    • 58149269201 scopus 로고    scopus 로고
    • Quantitative molecular imaging of viral therapy for pancreatic cancer using an engineered measles virus expressing the sodium-iodide symporter reporter gene
    • Carlson SK, Classic KL, Hadac EM, Dingli D, Bender CE, Kemp BJ, et al. Quantitative molecular imaging of viral therapy for pancreatic cancer using an engineered measles virus expressing the sodium-iodide symporter reporter gene. Am J Roentgenol. 2009; 192: 279–287.
    • (2009) Am J Roentgenol , vol.192 , pp. 279-287
    • Carlson, S.K.1    Classic, K.L.2    Hadac, E.M.3    Dingli, D.4    Bender, C.E.5    Kemp, B.J.6
  • 150
    • 34248678300 scopus 로고    scopus 로고
    • Visualization of telomerase reverse transcriptase (HTERT) promoter activity using a trimodality fusion reporter construct
    • Padmanabhan P, Otero J, Ray P, Paulmurugan R, Hoffman AR, Gambhir SS, et al. Visualization of telomerase reverse transcriptase (hTERT) promoter activity using a trimodality fusion reporter construct. J Nucl Med. 2006; 47: 270–277.
    • (2006) J Nucl Med , vol.47 , pp. 270-277
    • Padmanabhan, P.1    Otero, J.2    Ray, P.3    Paulmurugan, R.4    Hoffman, A.R.5    Gambhir, S.S.6
  • 151
    • 33748741534 scopus 로고    scopus 로고
    • Evaluation of transcriptional activity of the oestrogen receptor with sodium iodide symporter as an imaging reporter gene
    • Kang HJ, Chung J, Lee YJ, Kim K, Jeong JM, Lee DS, et al. Evaluation of transcriptional activity of the oestrogen receptor with sodium iodide symporter as an imaging reporter gene. Nucl Med Commun. 2006; 27: 773–777.
    • (2006) Nucl Med Commun , vol.27 , pp. 773-777
    • Kang, H.J.1    Chung, J.2    Lee, Y.J.3    Kim, K.4    Jeong, J.M.5    Lee, D.S.6
  • 152
    • 46749093827 scopus 로고    scopus 로고
    • Noninvasive imaging of cell-mediated therapy for treatment of cancer
    • Akins EJ, Dubey P. Noninvasive imaging of cell-mediated therapy for treatment of cancer. J Nucl Med. 2008; 49: 180S–195S.
    • (2008) J Nucl Med , vol.49 , pp. 180S-195S
    • Akins, E.J.1    Dubey, P.2
  • 156
    • 33751513037 scopus 로고    scopus 로고
    • Nuclear imaging in cardiac cell therapy
    • Bengel FM. Nuclear imaging in cardiac cell therapy. Heart Failure Reviews. 2006; 11: 325–332.
    • (2006) Heart Failure Reviews , vol.11 , pp. 325-332
    • Bengel, F.M.1
  • 159
    • 0032918091 scopus 로고    scopus 로고
    • Migration of human dendritic cells after injection in patients with metastatic malignancies
    • Morse MA, Coleman RE, Akabani G, Niehaus N, Coleman D, Lyerly HK. Migration of human dendritic cells after injection in patients with metastatic malignancies. Cancer Res. 1999; 59: 56–58.
    • (1999) Cancer Res , vol.59 , pp. 56-58
    • Morse, M.A.1    Coleman, R.E.2    Akabani, G.3    Niehaus, N.4    Coleman, D.5    Lyerly, H.K.6
  • 160
    • 23444432500 scopus 로고    scopus 로고
    • In vivo imaging platform for tracking immunotherapeutic cells
    • Ahrens ET, Flores R, Xu H, Morel PA. In vivo imaging platform for tracking immunotherapeutic cells. Nat Biotechnol. 2005; 23: 983–987.
    • (2005) Nat Biotechnol , vol.23 , pp. 983-987
    • Ahrens, E.T.1    Flores, R.2    Xu, H.3    Morel, P.A.4
  • 162
    • 0023838007 scopus 로고
    • Migration patterns of dendritic cells in the mouse: Homing to T cell-dependent areas of spleen and binding within marginal zone
    • Austyn JM, Kupiec-Weglinski JW, Hankins DF, Morris PJ. Migration patterns of dendritic cells in the mouse: homing to T cell-dependent areas of spleen and binding within marginal zone. J Exp Med. 1988; 167: 646–651.
    • (1988) J Exp Med , vol.167 , pp. 646-651
    • Austyn, J.M.1    Kupiec-Weglinski, J.W.2    Hankins, D.F.3    Morris, P.J.4
  • 163
    • 0036469805 scopus 로고    scopus 로고
    • Fluorine-18 labeled mouse bone marrow-derived dendritic cells can be detected in vivo by high resolution projection imaging
    • Olasz EB, Lang L, Seidel J, Green MV, Eckelman WC, Katz SI. Fluorine-18 labeled mouse bone marrow-derived dendritic cells can be detected in vivo by high resolution projection imaging. J Immunol Methods. 2002; 260: 137–148.
    • (2002) J Immunol Methods , vol.260 , pp. 137-148
    • Olasz, E.B.1    Lang, L.2    Seidel, J.3    Green, M.V.4    Eckelman, W.C.5    Katz, S.I.6
  • 164
    • 33749185306 scopus 로고    scopus 로고
    • Iron particles for noninvasive monitoring of bone marrow stromal cell engraftment into, and isolation of viable engrafted donor cells from, the heart
    • Stuckey DJ, Carr CA, Martin-Rendon E, Tyler DJ, Willmott C, Cassidy PJ, et al. Iron particles for noninvasive monitoring of bone marrow stromal cell engraftment into, and isolation of viable engrafted donor cells from, the heart. Stem Cells. 2006; 24: 1968–1975.
    • (2006) Stem Cells , vol.24 , pp. 1968-1975
    • Stuckey, D.J.1    Carr, C.A.2    Martin-Rendon, E.3    Tyler, D.J.4    Willmott, C.5    Cassidy, P.J.6
  • 166
    • 33646488229 scopus 로고    scopus 로고
    • Tracking transplanted cells using dual-radionuclide SPECT
    • Stodilka RZ, Blackwood KJ, Prato FS. Tracking transplanted cells using dual-radionuclide SPECT. Phys Med Biol. 2006; 51: 2619–2632.
    • (2006) Phys Med Biol , vol.51 , pp. 2619-2632
    • Stodilka, R.Z.1    Blackwood, K.J.2    Prato, F.S.3
  • 167
    • 0142188700 scopus 로고    scopus 로고
    • In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors
    • Kircher MF, Allport JR, Graves EE, Love V, Josephson L, Lichtman AH, et al. In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors. Cancer Res. 2003; 63: 6838–6846.
    • (2003) Cancer Res , vol.63 , pp. 6838-6846
    • Kircher, M.F.1    Allport, J.R.2    Graves, E.E.3    Love, V.4    Josephson, L.5    Lichtman, A.H.6
  • 169
    • 22644436414 scopus 로고    scopus 로고
    • Gadolinium-Rhodamine nanoparticles for cell labeling and tracking via magnetic resonance and optical imaging
    • Vuu K, Xie J, McDonald MA, Bernardo M, Hunter F, Zhang Y, et al. Gadolinium-Rhodamine nanoparticles for cell labeling and tracking via magnetic resonance and optical imaging. Bioconjug Chem. 2005; 16: 995–999.
    • (2005) Bioconjug Chem , vol.16 , pp. 995-999
    • Vuu, K.1    Xie, J.2    McDonald, M.A.3    Bernardo, M.4    Hunter, F.5    Zhang, Y.6
  • 170
    • 0037022647 scopus 로고    scopus 로고
    • Ex vivo cell labeling with 64Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for imaging cell trafficking in mice with positron-emission tomography
    • Adonai N, Nguyen KN, Walsh J, Iyer M, Toyokuni T, Phelps ME, et al. Ex vivo cell labeling with 64Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for imaging cell trafficking in mice with positron-emission tomography. PNAS. 2002; 99: 3030–3035.
    • (2002) PNAS , vol.99 , pp. 3030-3035
    • Adonai, N.1    Nguyen, K.N.2    Walsh, J.3    Iyer, M.4    Toyokuni, T.5    Phelps, M.E.6
  • 171
    • 37549066374 scopus 로고    scopus 로고
    • In vivo imaging and quantitation of adoptively transferred human antigen-specific T cells transduced to express a human norepinephrine transporter gene
    • Doubrovin MM, Doubrovina E, Zanzonico P, Sadelain M, Larson SM, O’Reilly RJ. In vivo imaging and quantitation of adoptively transferred human antigen-specific T cells transduced to express a human norepinephrine transporter gene. Cancer Res. 2007; 67: 11959–11969.
    • (2007) Cancer Res , vol.67 , pp. 11959-11969
    • Doubrovin, M.M.1    Doubrovina, E.2    Zanzonico, P.3    Sadelain, M.4    Larson, S.M.5    O’Reilly, R.J.6
  • 172
    • 51349141776 scopus 로고    scopus 로고
    • A novel cell-based therapy for contusion spinal cord injury using GDNF-delivering NIH3T3 cells with dual reporter genes monitored by molecular imaging
    • Lo W, Hsu C, Wu ATH, Yang L, Chen W, Chiu W, et al. A novel cell-based therapy for contusion spinal cord injury using GDNF-delivering NIH3T3 cells with dual reporter genes monitored by molecular imaging. J Nucl Med. 2008; 49: 1512–1519.
    • (2008) J Nucl Med , vol.49 , pp. 1512-1519
    • Lo, W.1    Hsu, C.2    Wu, A.3    Yang, L.4    Chen, W.5    Chiu, W.6
  • 173
    • 70349333986 scopus 로고    scopus 로고
    • RePETitive noninvasive monitoring of HSV1-tk-expressing T cells intravenously infused into nonhuman primates using positron emission tomography and computed tomography with 18F-FEAU
    • Dotti G, Tian M, Savoldo B, Najjar A, Cooper LJN, Jackson J, et al. RePETitive noninvasive monitoring of HSV1-tk-expressing T cells intravenously infused into nonhuman primates using positron emission tomography and computed tomography with 18F-FEAU. Mol Imaging. 2009; 8: 230–237.
    • (2009) Mol Imaging , vol.8 , pp. 230-237
    • Dotti, G.1    Tian, M.2    Savoldo, B.3    Najjar, A.4    Cooper, L.5    Jackson, J.6
  • 174
    • 34547521360 scopus 로고    scopus 로고
    • Monitoring the trafficking of adoptively transferred antigen-specific CD8-positive T cells in vivo, using non-invasive luminescence imaging
    • Kim D, Hung C, Wu T-C. Monitoring the trafficking of adoptively transferred antigen-specific CD8-positive T cells in vivo, using non-invasive luminescence imaging. Hum Gene Ther. 2007; 18: 575–588.
    • (2007) Hum Gene Ther , vol.18 , pp. 575-588
    • Kim, D.1    Hung, C.2    Wu, T.-C.3
  • 175
    • 22144494662 scopus 로고    scopus 로고
    • Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection and survival in transplantation
    • Cao Y, Bachmann MH, Beilhack A, Yang Y, Tanaka M, Swijnenburg R, et al. Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection and survival in transplantation. Transplantation. 2005; 80: 134–139.
    • (2005) Transplantation , vol.80 , pp. 134-139
    • Cao, Y.1    Bachmann, M.H.2    Beilhack, A.3    Yang, Y.4    Tanaka, M.5    Swijnenburg, R.6
  • 176
    • 27544508999 scopus 로고    scopus 로고
    • Ex vivo expanded dendritic cells home to T-cell zones of lymphoid organs and survive in vivo after allogeneic bone marrow transplantation
    • Schimmelpfennig CH, Schulz S, Arber C, Baker J, Tarner IH, McBride J, et al. Ex vivo expanded dendritic cells home to T-cell zones of lymphoid organs and survive in vivo after allogeneic bone marrow transplantation. Am J Pathol. 2005; 167: 1321–1331.
    • (2005) Am J Pathol , vol.167 , pp. 1321-1331
    • Schimmelpfennig, C.H.1    Schulz, S.2    Arber, C.3    Baker, J.4    Tarner, I.H.5    McBride, J.6
  • 177
    • 20844447232 scopus 로고    scopus 로고
    • Real-time in vivo imaging of stem cells following transgenesis by transposition
    • Tolar J, Osborn M, Bell S, McElmurry R, Xia L, Riddle M, et al. Real-time in vivo imaging of stem cells following transgenesis by transposition. Mol Ther. 2005; 12: 42–48.
    • (2005) Mol Ther , vol.12 , pp. 42-48
    • Tolar, J.1    Osborn, M.2    Bell, S.3    McElmurry, R.4    Xia, L.5    Riddle, M.6
  • 178
    • 55049116156 scopus 로고    scopus 로고
    • Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomography
    • Terrovitis J, Kwok KF, Lautamaki R, Engles JM, Barth AS, Kizana E, et al. Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomography. J Am Coll Cardiol. 2008; 52: 1652–1660.
    • (2008) J am Coll Cardiol , vol.52 , pp. 1652-1660
    • Terrovitis, J.1    Kwok, K.F.2    Lautamaki, R.3    Engles, J.M.4    Barth, A.S.5    Kizana, E.6
  • 179
    • 70350294615 scopus 로고    scopus 로고
    • Death and Proliferation Time Course of Stem Cells Transplanted in the Myocardium
    • Qiao H, Surti S, Choi SR, Raju K, Zhang H, Ponde DE, et al. Death and Proliferation Time Course of Stem Cells Transplanted in the Myocardium. Mol Imaging Biol. 2009; 11: 408–414.
    • (2009) Mol Imaging Biol , vol.11 , pp. 408-414
    • Qiao, H.1    Surti, S.2    Choi, S.R.3    Raju, K.4    Zhang, H.5    Ponde, D.E.6
  • 181
    • 36849015315 scopus 로고    scopus 로고
    • Noninvasive in vivo monitoring of neuronal differentiation using reporter driven by a neuronal promoter
    • Hwang DW, Kang JH, Jeong JM, Chung J, Lee MC, KIm S, et al. Noninvasive in vivo monitoring of neuronal differentiation using reporter driven by a neuronal promoter. Eur J Nucl Med Mol Imaging. 2008; 35: 135–145.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 135-145
    • Hwang, D.W.1    Kang, J.H.2    Jeong, J.M.3    Chung, J.4    Lee, M.C.5    Kim, S.6
  • 182
    • 33845400368 scopus 로고    scopus 로고
    • Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells
    • Wu JC, Cao F, Dutta S, Xie X, Kim E, Chungfat N, et al. Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells. Proteomics. 2006; 6: 6234–6249.
    • (2006) Proteomics , vol.6 , pp. 6234-6249
    • Wu, J.C.1    Cao, F.2    Dutta, S.3    Xie, X.4    Kim, E.5    Chungfat, N.6
  • 183
    • 66249088354 scopus 로고    scopus 로고
    • Transcriptional profiling of human mesenchymal stem cells transduced with reporter genes for imaging
    • Wang F, Dennis JE, Awadallah A, Solchaga LA, Molter J, Kuang Y, et al. Transcriptional profiling of human mesenchymal stem cells transduced with reporter genes for imaging. Physiol Genomics. 2009; 37: 23–34.
    • (2009) Physiol Genomics , vol.37 , pp. 23-34
    • Wang, F.1    Dennis, J.E.2    Awadallah, A.3    Solchaga, L.A.4    Molter, J.5    Kuang, Y.6
  • 184
    • 10644222780 scopus 로고    scopus 로고
    • Quantitation and visualization of tumor-specific T cells in the secondary lymphoid organs during and after tumor elimination by PET
    • Matsui K, Wang Z, McCarthy TJ, Allen PM, Reichert DE. Quantitation and visualization of tumor-specific T cells in the secondary lymphoid organs during and after tumor elimination by PET. Nucl Med Biol. 2004; 31: 1021–1031.
    • (2004) Nucl Med Biol , vol.31 , pp. 1021-1031
    • Matsui, K.1    Wang, Z.2    McCarthy, T.J.3    Allen, P.M.4    Reichert, D.E.5
  • 186
    • 70349646891 scopus 로고    scopus 로고
    • Radiolabeled humanized anti-CD3 monoclonal antibody Visilizumab for imaging human T-lymphocytes
    • Malviya G, D’ Alessandria C, Bonanno E, Vexler V, Massari R, Trotta C, et al. Radiolabeled humanized anti-CD3 monoclonal antibody Visilizumab for imaging human T-lymphocytes. J Nucl Med. 2009; 50: 1683–1691.
    • (2009) J Nucl Med , vol.50 , pp. 1683-1691
    • Malviya, G.1    D’ Alessandria, C.2    Bonanno, E.3    Vexler, V.4    Massari, R.5    Trotta, C.6
  • 187
    • 0037338436 scopus 로고    scopus 로고
    • Molecular imaging in living subjects: Seeing fundamental biological processes in a new light
    • Massoud TF, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. 2003; 17: 545–580.
    • (2003) Genes Dev , vol.17 , pp. 545-580
    • Massoud, T.F.1    Gambhir, S.S.2
  • 189
    • 54749122110 scopus 로고    scopus 로고
    • Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate
    • Barton KN, Stricker H, Brown SL, Elshaikh M, Aref I, Lu M, et al. Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate. Mol Ther. 2008; 16: 1761–1769.
    • (2008) Mol Ther , vol.16 , pp. 1761-1769
    • Barton, K.N.1    Stricker, H.2    Brown, S.L.3    Elshaikh, M.4    Aref, I.5    Lu, M.6
  • 190
    • 79955787256 scopus 로고    scopus 로고
    • Cell-specific imaging of reporter gene expression using a two-step transcriptional amplification strategy
    • Yaghoubi SS, Gambhir SS, editors
    • Figueiredo ML, Gambhir SS, Carey M, Wu L. Cell-specific imaging of reporter gene expression using a two-step transcriptional amplification strategy. In: Yaghoubi SS, Gambhir SS, editors. Molecular Imaging With Reporter Genes: Cambridge University Press, 2010; pp. 127–148.
    • (2010) Molecular Imaging with Reporter Genes: Cambridge University Press , pp. 127-148
    • Figueiredo, M.L.1    Gambhir, S.S.2    Carey, M.3    Wu, L.4


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