Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo

Cancer Research

Volumn 59, Issue 20, 1999, Pages 5186-5193

  Tjuvajev, Juri G ^a   Chen, Shu Hsia ^b   Joshi, Arjun ^a   Joshi, Revathi ^a   Guo, Zong Sheng ^b   Balatoni, Julius ^a   Ballon, Douglas ^a   Koutcher, Jason ^a   Finn, Ronald ^a   Woo, Savio L ^b   Blasberg, Ronald G ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLEVUDINE; GANCICLOVIR; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; CANCER SCINTISCANNING; COLON CARCINOMA; CONTROLLED STUDY; GENE THERAPY; GENE TRANSFER; HERPES SIMPLEX VIRUS 1; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; ROUS SARCOMA ONCOVIRUS;

ADENOVIRIDAE; ANIMALS; ARABINOFURANOSYLURACIL; AUTORADIOGRAPHY; COLONIC NEOPLASMS; GANCICLOVIR; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER TECHNIQUES; IODINE RADIOISOTOPES; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED BALB C; SIMPLEXVIRUS; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

EID: 0344564162     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Tjuvajev, J., Stockhammer, G., Desai, R., Uehara, H., Watanabe, K., Gansbacher, B., and Blasberg, R. Imaging the expression of transfected genes in vivo. Cancer Res., 55: 6126-6132, 1995.
2. Tjuvajev, J., Finn, R., Watanabe, K., Joshi, R., Oku, T., Kennedy, J., Beattie, B., Koutcher, J., Larson, S., and Blasberg, R. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res., 56: 4087-4095, 1996.
3. Tjuvajev, J. G., Avril, N., Oku, T., Sasajima, T., Miyagava, T., Joshi, R., Safer, M., Beattie, B., DiResta, G., Daghighian, F., Augensen, F., Koutcher, J., Finn, R., Zweit, J., Humm, J., Larson, S. M., and Blasberg, R. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res., 58: 4333-4341, 1998.
4. Berkner, K. L. Expression of heterologous sequences in adenoviral vectors. Curr. Top. Microbiol. Immunol., 158: 39-66, 1992.
5. Kozarsky, K. F., and Wilson, J. M. Gene therapy: adenovirus vectors. Curr. Opin. Genet. Dev., 3: 499-503, 1993.
6. Ali, M., Lemoine, N. R., and Ring, C. J. The use of DNA viruses as vectors for gene therapy. Gene Ther., 1: 367-384, 1994.
7. Culver, K. W., and Blaese, R. M. Gene therapy for cancer. Trends Genet., 10: 174-178, 1994.
8. Herrmann F. Cancer gene therapy: principles, problems, and perspectives. J. Mol. Med., 73: 157-163, 1995.
9. Xu, Z. Z., Krougliak, V., Prevec, L., Graham, F. L., and Both, G. W. Investigation of promoter function in human and animal cells infected with human recombinant adenovirus expressing rotavirus antigen VP7sc. J. Gen. Virol., 76: 1971-1980, 1995.
10. Johnson, L. G., Pickles, R. J., Boyles, S. E., Morris, J. C., Ye, H., Zhou, Z., Olsen, J. C., and Boucher, R. C. In vitro assessment of variables affecting the efficiency and efficacy of adenovirus-mediated gene transfer to cystic fibrosis airway epithelia. Hum. Gene Ther., 7: 51-59, 1996.
11. Zabner, J., Wadsworth, S. C., Smith, A. E., and Welsh, M. J. Adenovirus-mediated generation of cAMP-stimulated Cl-transport in cystic fibrosis airway epithelia in vitro: effect of promoter and administration method. Gene Ther., 3: 458-465, 1996.
12. Guo, Z. S., Wang, L. H., Eisensmith, R. C., and Woo, S. L. Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer. Gene Ther., 3: 802-810, 1996.
13. Chen, S. H., Chen, X. H., Wang, Y., Kosai, K., Finegold, M. J., Rich, S. S., and Woo, S. L. Combination gene therapy for liver metastasis of colon carcinoma in vivo. Proc. Natl. Acad. Sci. USA, 92: 2577-2581, 1995.
14. Chen, S. H., Kosai, K., Xu, B., Pham-Nguyen, K., Contant, C., Finegold, M. J., and Woo, S. L. Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival. Cancer Res., 56: 3758-3762, 1996.
15. Corbett, T. H., Griswold, D. P., Jr., Roberts, B. J., Peckham, J. C., and Schabel, F. M., Jr. Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res., 35: 2434-2439, 1975.
16. Graham, F. L., Smiley, J., Russell, W. C., and Naim, R. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol., 36: 59-74, 1977.
17. Moolten, F. L., and Wells, J. M. Curability of tumors bearing herpes thymidine kinase genes transfected by retroviral vectors. J. Natl. Cancer Inst., 82: 297-300, 1990.
18. Chen, S. H., Shine, H. D., Goodman, J. C., Grossman, R. G., and Woo, S. L. Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc. Natl. Acad. Sci. USA, 91: 3054-3057, 1994.
19. Fang B., Eisensmith R. C., Li X. H., Finegold M. J., Shedlovsky A., Dove W., and Woo S. L. Gene therapy for phenylketonuria: phenotypic correction in a genetically deficient mouse model by adenovirus-mediated hepatic gene transfer. Gene Ther., 1: 247-254, 1994.
20. Graham, F. L., and van der Eb, A. J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology, 52: 456-467, 1973.
21. Ballon, D., Graham, M. C., and Koutcher, I. A. Doubly tuned solenoidal resonators for high spatial resolution small animal imaging and spectroscopy. Magn. Reson. Imaging, 7: 155-162, 1989.
22. Gambhir, S. S., Barrio, J. R., Wu, L., Iyer, M., Namavari, M., Satyamurthy, N., Bauer, E., Parrish, C., MacLaren, D. C., Borghei, A. R, Green, L. A., Sharfstein, S., Berk, A. J., Cherry, S. R., Phelps, M. E., and Herschman, H. R. Imaging of adenoviral-directed herpes simplex virus type I thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J. Nucl. Med., 39: 2003-2011, 1998.
23. Gambhir, S. S., Barrio, J. R., Phelps, M. E., Iyer, M., Namavari, M., Satyamurthy, N., Wu, L., Green, L. A., Bauer, E., MacLaren, D. C., Nguyen, K., Berk, A. J., Cherry, S. R., and Herschman, H. R. Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography. Proc. Natl. Acad. Sci. USA, 96: 2333-2338, 1999.
24. Gambhir, S. S., Barrio, J. R., Bauer, E., Iyer, M., Namavari, M., Satyamurthy, N , Shah, P. Toyokuni, T., Wu, L., Berk, A. J., Phelps, M. E., and Herschman, H. Radiolabeled penciclovir: a new reporter probe with improved imaging properties over ganciclovir for imaging herpes-simplex virus type 1 thymidine kinase reporter gene expression. J. Nucl. Med., 39 (Suppl.): 53P, 1998.